JP2022105175A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2022105175A5 JP2022105175A5 JP2022076671A JP2022076671A JP2022105175A5 JP 2022105175 A5 JP2022105175 A5 JP 2022105175A5 JP 2022076671 A JP2022076671 A JP 2022076671A JP 2022076671 A JP2022076671 A JP 2022076671A JP 2022105175 A5 JP2022105175 A5 JP 2022105175A5
- Authority
- JP
- Japan
- Prior art keywords
- testosterone
- gel formulation
- pharmaceutically acceptable
- mixture
- testosterone gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 claims 122
- 239000000203 mixture Substances 0.000 claims 63
- 229960003604 testosterone Drugs 0.000 claims 61
- 238000009472 formulation Methods 0.000 claims 51
- 238000000034 method Methods 0.000 claims 13
- 239000003981 vehicle Substances 0.000 claims 9
- 238000009792 diffusion process Methods 0.000 claims 6
- 206010002261 Androgen deficiency Diseases 0.000 claims 5
- 206010058359 Hypogonadism Diseases 0.000 claims 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 5
- 238000009165 androgen replacement therapy Methods 0.000 claims 5
- 229940075614 colloidal silicon dioxide Drugs 0.000 claims 5
- 125000002811 oleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 5
- 239000002904 solvent Substances 0.000 claims 5
- 239000000651 prodrug Substances 0.000 claims 4
- 229940002612 prodrug Drugs 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 229940126601 medicinal product Drugs 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 229940127557 pharmaceutical product Drugs 0.000 claims 3
- 239000004359 castor oil Substances 0.000 claims 2
- 235000019438 castor oil Nutrition 0.000 claims 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 2
- 239000003906 humectant Substances 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161486324P | 2011-05-15 | 2011-05-15 | |
| US61/486,324 | 2011-05-15 | ||
| US201161486634P | 2011-05-16 | 2011-05-16 | |
| US61/486,634 | 2011-05-16 | ||
| JP2020012807A JP2020079257A (ja) | 2011-05-15 | 2020-01-29 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020012807A Division JP2020079257A (ja) | 2011-05-15 | 2020-01-29 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022105175A JP2022105175A (ja) | 2022-07-12 |
| JP2022105175A5 true JP2022105175A5 (enExample) | 2022-10-06 |
Family
ID=46579248
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510901A Expired - Fee Related JP6152092B2 (ja) | 2011-05-15 | 2012-05-15 | 経鼻投与のための徐放テストステロン鼻腔内ゲル、方法および複数回用量プレフィルアプリケーターシステム |
| JP2014510900A Pending JP2014513716A (ja) | 2011-05-15 | 2012-05-15 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2017056679A Expired - Fee Related JP6594924B2 (ja) | 2011-05-15 | 2017-03-22 | 経鼻投与のための徐放テストステロン鼻腔内ゲル、方法および複数回用量プレフィルアプリケーターシステム |
| JP2018158566A Pending JP2018199701A (ja) | 2011-05-15 | 2018-08-27 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2019173990A Active JP7017254B2 (ja) | 2011-05-15 | 2019-09-25 | 経鼻投与のための徐放テストステロン鼻腔内ゲル、方法および複数回用量プレフィルアプリケーターシステム |
| JP2020012807A Pending JP2020079257A (ja) | 2011-05-15 | 2020-01-29 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2020157216A Pending JP2021001206A (ja) | 2011-05-15 | 2020-09-18 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2022034334A Pending JP2022078222A (ja) | 2011-05-15 | 2022-03-07 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2022076671A Pending JP2022105175A (ja) | 2011-05-15 | 2022-05-06 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
Family Applications Before (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510901A Expired - Fee Related JP6152092B2 (ja) | 2011-05-15 | 2012-05-15 | 経鼻投与のための徐放テストステロン鼻腔内ゲル、方法および複数回用量プレフィルアプリケーターシステム |
| JP2014510900A Pending JP2014513716A (ja) | 2011-05-15 | 2012-05-15 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2017056679A Expired - Fee Related JP6594924B2 (ja) | 2011-05-15 | 2017-03-22 | 経鼻投与のための徐放テストステロン鼻腔内ゲル、方法および複数回用量プレフィルアプリケーターシステム |
| JP2018158566A Pending JP2018199701A (ja) | 2011-05-15 | 2018-08-27 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2019173990A Active JP7017254B2 (ja) | 2011-05-15 | 2019-09-25 | 経鼻投与のための徐放テストステロン鼻腔内ゲル、方法および複数回用量プレフィルアプリケーターシステム |
| JP2020012807A Pending JP2020079257A (ja) | 2011-05-15 | 2020-01-29 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2020157216A Pending JP2021001206A (ja) | 2011-05-15 | 2020-09-18 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
| JP2022034334A Pending JP2022078222A (ja) | 2011-05-15 | 2022-03-07 | 鼻腔内テストステロン生体付着性ゲル製剤および男性の性腺機能低下症の治療のためのその使用 |
Country Status (16)
| Country | Link |
|---|---|
| EP (3) | EP2709588B1 (enExample) |
| JP (9) | JP6152092B2 (enExample) |
| KR (10) | KR20190117803A (enExample) |
| CN (4) | CN110613679A (enExample) |
| AR (2) | AR089553A1 (enExample) |
| AU (11) | AU2012257490A1 (enExample) |
| BR (2) | BR112013029336B1 (enExample) |
| CA (3) | CA2836398C (enExample) |
| DK (1) | DK2714006T3 (enExample) |
| EA (1) | EA201391701A1 (enExample) |
| ES (1) | ES2859784T3 (enExample) |
| IL (2) | IL229400A0 (enExample) |
| MX (4) | MX363561B (enExample) |
| PL (1) | PL2714006T3 (enExample) |
| WO (2) | WO2012156820A1 (enExample) |
| ZA (2) | ZA201309264B (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR086400A1 (es) | 2011-05-13 | 2013-12-11 | Trimel Pharmaceuticals Corp | Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo |
| US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
| CA2836398C (en) * | 2011-05-15 | 2021-12-14 | Trimel Biopharma Srl | Intranasal testosterone bio-adhesive gel formulations and use thereof for treating male hypogonadism |
| US8971800B2 (en) * | 2011-05-31 | 2015-03-03 | Qualcomm Incorporated | Methods and apparatus for improving NFC activation and data exchange reporting mechanisms |
| BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| WO2014076569A2 (en) * | 2012-11-14 | 2014-05-22 | Trimel Biopharma Srl | Controlled release topical testosterone formulations and methods |
| US20140171918A1 (en) * | 2012-12-14 | 2014-06-19 | Bioject, Inc. | Use of a novel subcutaneous needle-free technique to deliver testosterone in hypogonadal men |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
| JP6338658B2 (ja) * | 2013-10-07 | 2018-06-06 | アンタレス・ファーマ・インコーポレーテッド | テストステロンの針補助ジェット注射を通じたヘマトクリット調節 |
| JP2017513809A (ja) | 2014-02-19 | 2017-06-01 | アンタレス・ファーマ・インコーポレーテッド | テストステロン組成物の針に補助されるジェット注射投与 |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| AU2015296609A1 (en) | 2014-07-29 | 2016-12-22 | Therapeuticsmd, Inc. | Transdermal cream |
| TW201636045A (zh) * | 2015-01-28 | 2016-10-16 | 波美西恩製藥有限責任公司 | 組成物、促進或增強受試者之局部毛髮飽滿度及厚度或毛髮生長之方法、包括該組成物之套組及裝置 |
| US20160374800A1 (en) * | 2015-06-29 | 2016-12-29 | Changcheng You | Implantable scaffolds for treatment of sinusitis |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| BR102015020878B1 (pt) * | 2015-08-28 | 2019-08-27 | F B M Ind Farmaceutica Ltda | formulação farmacêutica nasal de testosterona e “kit” em forma de cartela de dispositivos nasais unitários para aplicação de monodose de testosterona. |
| KR20180117103A (ko) * | 2016-01-07 | 2018-10-26 | 비라말 리미티드 | 각질층 및 혈청 중의 약물 농도를 최대로 하기 위한 경피 전달용 겔 조성물 및 그의 사용 방법 |
| KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| CN109069750B (zh) | 2016-04-25 | 2021-09-07 | 科斯卡家族有限公司 | 药物输送系统 |
| WO2017208072A2 (en) * | 2016-06-02 | 2017-12-07 | Acerus Pharmaceutical Corporation | Nasal cannabidiol compositions |
| EA201892595A1 (ru) | 2016-06-03 | 2019-06-28 | М Эт П Фарма Аг | Назальные фармацевтические композиции с пористым наполнителем |
| CA3050361A1 (en) * | 2017-01-20 | 2018-07-26 | M et P Pharma AG | Nasal pharmaceutical compositions for reducing the risks of exposure to air pollutants |
| EP3641424B1 (en) | 2017-06-17 | 2022-05-04 | LG Electronics Inc. | Method for registering a user equipment with a network slice in a wireless communication system and user equipment therefor |
| CN111615409A (zh) | 2017-11-17 | 2020-09-01 | 科斯卡家族有限公司 | 用于流体输送歧管的系统和方法 |
| US11234928B2 (en) * | 2017-11-27 | 2022-02-01 | Aska Pharmaceutical Co., Ltd. | Powder preparation for nasal administration |
| PL3710012T3 (pl) | 2018-02-02 | 2025-11-17 | Acerus Biopharma Inc. | Sposoby terapii testosteronem |
| WO2019175290A1 (en) | 2018-03-13 | 2019-09-19 | Beckley Canopy Therapeutics Limited | Cannabis or cannabis derived compositions for promoting cessation of chemical dependence |
| CN108771622B (zh) * | 2018-07-11 | 2022-01-07 | 尹振图 | 一种自闭式针形滴嘴及眼药水瓶 |
| BR112021007877A2 (pt) | 2018-10-26 | 2021-08-03 | Viramal Limited | composição em gel mucoadesiva |
| ES2948955T3 (es) | 2018-11-30 | 2023-09-22 | Viramal Ltd | Un método de preparación de un agente gelificante, el agente gelificante obtenido de este modo y el uso de dicho agente gelificante |
| US20200170962A1 (en) | 2018-11-30 | 2020-06-04 | F. Markus Leweke | Nasal cannabidiol compositions |
| MX2021007032A (es) * | 2018-12-14 | 2021-10-22 | Acerus Biopharma Inc | Derivados activos de éster de testosterona, composiciones y usos de los mismos. |
| USD1052082S1 (en) | 2020-06-01 | 2024-11-19 | Koska Family Limited | Sealed fluid container |
| CN112121049B (zh) * | 2020-08-28 | 2022-02-01 | 嘉兴市第一医院 | 顺式阿曲库铵在制备治疗男性性腺功能减退症的药物中的应用 |
| CN116600787A (zh) * | 2020-11-19 | 2023-08-15 | 阿库西亚医疗有限责任公司 | 非水性凝胶组合物 |
| GB202307501D0 (en) * | 2023-05-19 | 2023-07-05 | Lawley Pharmaceuticals Pty Ltd | Process for preparing dispensable testosterone cream |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4082881A (en) * | 1976-12-23 | 1978-04-04 | E. R. Squibb & Sons, Inc. | Topical and other type pharmaceutical formulations containing isosorbide carrier |
| DE4214953C2 (de) | 1992-05-06 | 1995-05-18 | Arrowdean Ltd | Arzneimittel zur Erhöhung des Testosteronspiegels |
| US5756071A (en) | 1992-06-03 | 1998-05-26 | Arrowdean Limited | Method for nasally administering aerosols of therapeutic agents to enhance penetration of the blood brain barrier |
| DE4405898A1 (de) * | 1994-02-18 | 1995-08-24 | Schering Ag | Transdermale therapeutische Systeme enthaltend Sexualsteroide |
| US5576071A (en) | 1994-11-08 | 1996-11-19 | Micron Technology, Inc. | Method of reducing carbon incorporation into films produced by chemical vapor deposition involving organic precursor compounds |
| JP2000514065A (ja) * | 1997-07-03 | 2000-10-24 | アルザ コーポレイション | ドラッグデリバリーディバイスとその製造法 |
| BR9814014B1 (pt) * | 1997-11-10 | 2014-10-07 | Strakan Int Ltd | Composição para aplicação tópica tendo propriedades de melhora da penetração |
| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| DE10064950A1 (de) * | 2000-12-23 | 2002-07-11 | Impetus Ag Basel | Thixotropes Nasenspray |
| JP2005505587A (ja) * | 2001-10-12 | 2005-02-24 | シーエヌエス・インコーポレーテッド | 含水性の点鼻ゲル及びその塗布装置 |
| MY139721A (en) * | 2002-04-19 | 2009-10-30 | Cpex Pharmaceuticals Inc | Pharmaceutical composition |
| IL152575A (en) * | 2002-10-31 | 2008-12-29 | Transpharma Medical Ltd | A skin-to-skin transmission system of water-insoluble drugs |
| ATE534373T1 (de) * | 2003-10-10 | 2011-12-15 | Antares Pharma Ipl Ag | Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut |
| DK1530965T3 (da) * | 2003-11-11 | 2006-07-17 | Mattern Udo | Kontrolleret frigivelsesleveringssystem til nasal applikation |
| WO2006061155A2 (de) * | 2004-12-09 | 2006-06-15 | Bayer Healthcare Ag | Stabilisierung von glucocorticoidestern mit säuren |
| EP1896038B1 (en) * | 2005-06-03 | 2016-11-09 | Acrux DDS Pty Ltd | Method and composition for testosterone transdermal delivery |
| EP1790343A1 (en) * | 2005-11-11 | 2007-05-30 | Emotional Brain B.V. | Pharmaceuticals formulations and uses thereof in the treatment of female sexual dysfunction |
| CN101099742A (zh) * | 2006-07-06 | 2008-01-09 | 上海富海科申药业有限公司 | 能够减少皮肤刺激的睾酮凝胶制剂 |
| ES2358619T3 (es) * | 2006-10-04 | 2011-05-12 | M & P PATENT AKTIENGESELLSCHAFT | Sistema de administración de liberación controlada para aplicación nasal de neurotransmisores. |
| AU2008231781B2 (en) * | 2007-03-23 | 2012-09-20 | Besins Healthcare Luxembourg Sarl | Compositions and method for treating pediatric hypogonadism |
| JP4825305B2 (ja) * | 2007-09-20 | 2011-11-30 | 株式会社 資生堂 | 経皮吸収製剤 |
| EP2949361B1 (en) * | 2007-11-13 | 2017-03-22 | Athenion AG | C-19 steroids for treating cellulite |
| GB0807605D0 (en) * | 2008-04-28 | 2008-06-04 | Diurnal Ltd | Lipid composition |
| CA2836398C (en) * | 2011-05-15 | 2021-12-14 | Trimel Biopharma Srl | Intranasal testosterone bio-adhesive gel formulations and use thereof for treating male hypogonadism |
-
2012
- 2012-05-15 CA CA2836398A patent/CA2836398C/en active Active
- 2012-05-15 BR BR112013029336-5A patent/BR112013029336B1/pt active IP Right Grant
- 2012-05-15 AU AU2012257490A patent/AU2012257490A1/en not_active Abandoned
- 2012-05-15 JP JP2014510901A patent/JP6152092B2/ja not_active Expired - Fee Related
- 2012-05-15 DK DK12748245.3T patent/DK2714006T3/da active
- 2012-05-15 EP EP12738595.3A patent/EP2709588B1/en active Active
- 2012-05-15 CA CA3034552A patent/CA3034552C/en active Active
- 2012-05-15 KR KR1020197029484A patent/KR20190117803A/ko not_active Ceased
- 2012-05-15 CN CN201910982324.2A patent/CN110613679A/zh active Pending
- 2012-05-15 CN CN201280035150.5A patent/CN103796636B/zh not_active Expired - Fee Related
- 2012-05-15 WO PCT/IB2012/001112 patent/WO2012156820A1/en not_active Ceased
- 2012-05-15 KR KR1020207028301A patent/KR20200118228A/ko not_active Ceased
- 2012-05-15 CN CN201811198846.5A patent/CN109481394B/zh active Active
- 2012-05-15 BR BR112013029332-2A patent/BR112013029332A2/pt not_active Application Discontinuation
- 2012-05-15 MX MX2013013388A patent/MX363561B/es unknown
- 2012-05-15 MX MX2020008599A patent/MX395212B/es unknown
- 2012-05-15 KR KR1020137033180A patent/KR20140033408A/ko not_active Ceased
- 2012-05-15 KR KR1020187038088A patent/KR102088038B1/ko active Active
- 2012-05-15 CA CA2836405A patent/CA2836405C/en active Active
- 2012-05-15 WO PCT/IB2012/001127 patent/WO2012156822A1/en not_active Ceased
- 2012-05-15 KR KR1020217036024A patent/KR20210135003A/ko not_active Ceased
- 2012-05-15 KR KR1020237008221A patent/KR20230041081A/ko not_active Ceased
- 2012-05-15 EP EP21191386.8A patent/EP3977982A1/en not_active Withdrawn
- 2012-05-15 KR KR1020137033181A patent/KR20140045400A/ko not_active Ceased
- 2012-05-15 KR KR1020217007047A patent/KR102568894B1/ko active Active
- 2012-05-15 PL PL12748245T patent/PL2714006T3/pl unknown
- 2012-05-15 CN CN201280035162.8A patent/CN103813784A/zh active Pending
- 2012-05-15 KR KR1020207006630A patent/KR20200028503A/ko not_active Ceased
- 2012-05-15 KR KR1020247037387A patent/KR20240162608A/ko active Pending
- 2012-05-15 MX MX2013013369A patent/MX2013013369A/es unknown
- 2012-05-15 EP EP12748245.3A patent/EP2714006B1/en active Active
- 2012-05-15 AU AU2012257492A patent/AU2012257492A1/en not_active Abandoned
- 2012-05-15 EA EA201391701A patent/EA201391701A1/ru unknown
- 2012-05-15 MX MX2019003340A patent/MX374398B/es active IP Right Grant
- 2012-05-15 JP JP2014510900A patent/JP2014513716A/ja active Pending
- 2012-05-15 ES ES12748245T patent/ES2859784T3/es active Active
- 2012-05-16 AR ARP120101721A patent/AR089553A1/es not_active Application Discontinuation
- 2012-05-16 AR ARP120101720A patent/AR086409A1/es not_active Application Discontinuation
-
2013
- 2013-11-11 IL IL229400A patent/IL229400A0/en unknown
- 2013-11-11 IL IL229401A patent/IL229401A0/en unknown
- 2013-12-09 ZA ZA2013/09264A patent/ZA201309264B/en unknown
- 2013-12-09 ZA ZA2013/09265A patent/ZA201309265B/en unknown
-
2017
- 2017-03-22 JP JP2017056679A patent/JP6594924B2/ja not_active Expired - Fee Related
- 2017-05-24 AU AU2017203470A patent/AU2017203470A1/en not_active Abandoned
- 2017-06-20 AU AU2017204182A patent/AU2017204182A1/en not_active Abandoned
-
2018
- 2018-08-27 JP JP2018158566A patent/JP2018199701A/ja active Pending
-
2019
- 2019-03-08 AU AU2019201618A patent/AU2019201618A1/en not_active Abandoned
- 2019-04-30 AU AU2019203067A patent/AU2019203067A1/en not_active Abandoned
- 2019-05-15 AU AU2019203400A patent/AU2019203400A1/en not_active Abandoned
- 2019-09-25 JP JP2019173990A patent/JP7017254B2/ja active Active
-
2020
- 2020-01-29 JP JP2020012807A patent/JP2020079257A/ja active Pending
- 2020-07-29 AU AU2020210227A patent/AU2020210227A1/en not_active Abandoned
- 2020-09-18 JP JP2020157216A patent/JP2021001206A/ja active Pending
- 2020-11-09 AU AU2020267162A patent/AU2020267162B2/en not_active Ceased
-
2022
- 2022-03-07 JP JP2022034334A patent/JP2022078222A/ja active Pending
- 2022-04-12 AU AU2022202402A patent/AU2022202402A1/en not_active Abandoned
- 2022-05-06 JP JP2022076671A patent/JP2022105175A/ja active Pending
-
2024
- 2024-08-23 AU AU2024216312A patent/AU2024216312A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022105175A5 (enExample) | ||
| ES2314408T3 (es) | Formulaciones de hfc en solucion que contienen un anticolinergico. | |
| RU2228177C2 (ru) | Назальная композиция и способ профилактики и лечения простуды и гриппа вирусного происхождения | |
| JP6063094B2 (ja) | 経皮送達を促進するためのペプチド | |
| JP6112867B2 (ja) | サキシトキシン誘導体での触覚の喪失の処置 | |
| KR20150136077A (ko) | 국소 조성물 및 국소 질환의 치료 방법 | |
| CA2883751A1 (en) | Methods of treating alzheimer's disease and pharmaceutical compositions thereof | |
| TW201105334A (en) | Topical formulation containing a tetracycline and a method of treating skin infections using the same | |
| JP2016527188A5 (enExample) | ||
| ES3029560T3 (en) | 5-amino-2,3-dihydro-1,4-phthalazinedione as glucocorticoid-sparing agent | |
| UA75059C2 (uk) | Фармацевтична композиція, що містить золмітриптан, спосіб її приготування, пристрій для інтраназального введення та застосування золмітриптану для приготування композиції | |
| JP2018520198A5 (enExample) | ||
| JPH09176013A (ja) | 急性鼻炎を処置するための医薬製剤 | |
| US20160339026A1 (en) | Topical compositions comprising modulators of trpm8 | |
| WO2005000287A1 (ja) | 水虫治療用外用剤 | |
| KR20250143851A (ko) | 신규한 다기능성 올리고펩타이드 | |
| CN101505797A (zh) | 用于真菌感染的治疗的药物组合物 | |
| JP2005531612A (ja) | ネフォパムの製剤および痛みの治療におけるその使用 | |
| US20220395577A1 (en) | Methods and materials for modulating nrf2 pathway | |
| JP2017516829A5 (enExample) | ||
| JPH10502628A (ja) | 長時間作用オキシテトラサイクリン組成物 | |
| US20220202737A1 (en) | Treatment of hidradenitis suppurativa with tapinarof compositions | |
| JP2011524366A (ja) | 鼻内投与のためのケトロラクの薬学的処方物 | |
| CN108721215A (zh) | 艾氟康唑微乳组合物 | |
| WO2024044674A1 (en) | Dna origami vaccines |