JP2021516242A5 - - Google Patents
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- Publication number
- JP2021516242A5 JP2021516242A5 JP2020547089A JP2020547089A JP2021516242A5 JP 2021516242 A5 JP2021516242 A5 JP 2021516242A5 JP 2020547089 A JP2020547089 A JP 2020547089A JP 2020547089 A JP2020547089 A JP 2020547089A JP 2021516242 A5 JP2021516242 A5 JP 2021516242A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- unsubstituted
- substituted
- compound according
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023100100A JP7614255B2 (ja) | 2018-03-09 | 2023-06-19 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2024229980A JP7726563B2 (ja) | 2018-03-09 | 2024-12-26 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2025128531A JP2025160419A (ja) | 2018-03-09 | 2025-07-31 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862641149P | 2018-03-09 | 2018-03-09 | |
| US62/641,149 | 2018-03-09 | ||
| US201862755163P | 2018-11-02 | 2018-11-02 | |
| US62/755,163 | 2018-11-02 | ||
| PCT/US2019/019557 WO2019173082A1 (en) | 2018-03-09 | 2019-02-26 | Substituted l,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023100100A Division JP7614255B2 (ja) | 2018-03-09 | 2023-06-19 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021516242A JP2021516242A (ja) | 2021-07-01 |
| JP2021516242A5 true JP2021516242A5 (enExample) | 2023-02-20 |
| JP7300460B2 JP7300460B2 (ja) | 2023-06-29 |
Family
ID=67845731
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020547089A Active JP7300460B2 (ja) | 2018-03-09 | 2019-02-26 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2023100100A Active JP7614255B2 (ja) | 2018-03-09 | 2023-06-19 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2024229980A Active JP7726563B2 (ja) | 2018-03-09 | 2024-12-26 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2025128531A Pending JP2025160419A (ja) | 2018-03-09 | 2025-07-31 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023100100A Active JP7614255B2 (ja) | 2018-03-09 | 2023-06-19 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2024229980A Active JP7726563B2 (ja) | 2018-03-09 | 2024-12-26 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
| JP2025128531A Pending JP2025160419A (ja) | 2018-03-09 | 2025-07-31 | 置換１，２－ジヒドロ－３Ｈ－ピラゾロ［３，４－ｄ］ピリミジン－３－オン |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US11261192B2 (enExample) |
| EP (2) | EP4566612A3 (enExample) |
| JP (4) | JP7300460B2 (enExample) |
| KR (2) | KR20250073542A (enExample) |
| CN (3) | CN117285532A (enExample) |
| AU (2) | AU2019231551B2 (enExample) |
| BR (1) | BR112020018286A2 (enExample) |
| CA (1) | CA3089746A1 (enExample) |
| DK (1) | DK3762385T3 (enExample) |
| ES (1) | ES3024692T3 (enExample) |
| FI (1) | FI3762385T3 (enExample) |
| HR (1) | HRP20250517T1 (enExample) |
| HU (1) | HUE071131T2 (enExample) |
| IL (2) | IL276802B2 (enExample) |
| LT (1) | LT3762385T (enExample) |
| MX (2) | MX2020009372A (enExample) |
| PL (1) | PL3762385T3 (enExample) |
| PT (1) | PT3762385T (enExample) |
| RS (1) | RS66798B1 (enExample) |
| SG (1) | SG11202006906XA (enExample) |
| SI (1) | SI3762385T1 (enExample) |
| TW (2) | TWI822733B (enExample) |
| WO (1) | WO2019173082A1 (enExample) |
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| EP3694861A4 (en) | 2017-10-09 | 2021-05-19 | Nuvation Bio Inc. | HETEROCYCLIC COMPOUNDS AND USES THEREOF |
| AU2018347307A1 (en) | 2017-10-09 | 2020-04-23 | Nuvation Bio Inc. | Heterocyclic compounds and uses thereof |
| EP4566612A3 (en) | 2018-03-09 | 2025-08-20 | Recurium IP Holdings, LLC | Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
| AU2020208644A1 (en) | 2019-01-18 | 2021-08-26 | Nuvation Bio Inc. | Heterocyclic compounds as adenosine antagonists |
| WO2020150676A1 (en) | 2019-01-18 | 2020-07-23 | Nuvation Bio Inc. | 1,8-naphthyridinone compounds and uses thereof |
| US20220220115A1 (en) * | 2019-04-09 | 2022-07-14 | Nuvation Bio Inc. | Heterocyclic compounds and uses thereof |
| JP2022526831A (ja) | 2019-04-09 | 2022-05-26 | ニューベイション・バイオ・インコーポレイテッド | ヘテロ環式化合物およびその使用 |
| US20220169646A1 (en) * | 2019-04-09 | 2022-06-02 | Nuvation Bio Inc. | Heterocyclic compounds and uses thereof |
| WO2020210320A1 (en) * | 2019-04-11 | 2020-10-15 | Recurium Ip Holdings, Llc | Substituted l,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
| BR112021026618A2 (pt) | 2019-06-28 | 2022-06-07 | Shanghai Pharmaceuticals Holding Co Ltd | Composto de pirazolpirimidina, método de preparação do mesmo e aplicações do mesmo |
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| AU2020384291A1 (en) * | 2019-11-15 | 2022-05-26 | Recurium Ip Holdings, Llc | Chiral synthesis of a tertiary alcohol |
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| KR20220119658A (ko) * | 2019-12-20 | 2022-08-30 | 리커리엄 아이피 홀딩스, 엘엘씨 | 조합물 |
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| CN116848118A (zh) * | 2021-02-09 | 2023-10-03 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的吡唑并[3,4-d]嘧啶-3-酮衍生物 |
| WO2022171126A1 (zh) * | 2021-02-09 | 2022-08-18 | 微境生物医药科技(上海)有限公司 | 作为Wee-1抑制剂的稠环化合物 |
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| AU2022259496A1 (en) * | 2021-04-12 | 2023-10-12 | Recurium Ip Holdings, Llc | Wee1 compound for treating uterine serous carcinoma |
| KR20240004539A (ko) | 2021-04-30 | 2024-01-11 | 위겐 바이오메더슨 테크널러지 (상하이) 컴퍼니 리미티드 | Wee-1 억제제로서의 축합 고리 화합물, 그를 위한 제조 방법 및 그의 용도 |
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| EP4566612A3 (en) * | 2018-03-09 | 2025-08-20 | Recurium IP Holdings, LLC | Substituted 1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
| KR102637792B1 (ko) | 2018-03-22 | 2024-02-19 | 삼성디스플레이 주식회사 | 유기 발광 소자 및 이를 포함한 전자 장치 |
| CN108794493B (zh) | 2018-04-28 | 2020-04-24 | 北京施安泰医药技术开发有限公司 | 四氢吡咯并[2,1-h]蝶啶-6(5H)-酮衍生物、其药物组合物、制备方法和应用 |
| CN108794484B (zh) | 2018-04-28 | 2020-04-24 | 北京施安泰医药技术开发有限公司 | [1,2,4]三唑并[4,3-a]吡嗪衍生物、其药物组合物、制备方法和应用 |
| KR102328435B1 (ko) | 2018-09-11 | 2021-11-18 | 재단법인 대구경북첨단의료산업진흥재단 | 신규 피리도-피리미딘 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 단백질 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물 |
| CN109651337A (zh) | 2018-12-30 | 2019-04-19 | 瑞声科技（南京）有限公司 | 发光组合物及包含该发光组合物的发光层和电致发光器件 |
| KR102860612B1 (ko) | 2019-03-25 | 2025-09-15 | 삼성전자주식회사 | 유기금속 화합물, 이를 포함한 유기 발광 소자 및 이를 포함한 진단용 조성물 |
| WO2020210320A1 (en) | 2019-04-11 | 2020-10-15 | Recurium Ip Holdings, Llc | Substituted l,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-ones |
| CN112142748B (zh) | 2019-06-28 | 2023-07-04 | 上海医药集团股份有限公司 | 一种吡唑酮并嘧啶类化合物、其制备方法及应用 |
| JP2023507797A (ja) | 2019-12-20 | 2023-02-27 | リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー | 組み合わせ |
| AU2020407070A1 (en) | 2019-12-20 | 2022-07-14 | Recurium Ip Holdings, Llc | Combinations |
| AU2020404996A1 (en) | 2019-12-20 | 2022-07-14 | Recurium Ip Holdings, Llc | Combinations |
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2019
- 2019-02-26 EP EP25156816.8A patent/EP4566612A3/en active Pending
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- 2019-02-26 EP EP19764330.7A patent/EP3762385B1/en active Active
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- 2019-02-26 CN CN201980021575.2A patent/CN111902413B/zh active Active
- 2019-02-26 RS RS20250397A patent/RS66798B1/sr unknown
- 2019-02-26 PT PT197643307T patent/PT3762385T/pt unknown
- 2019-02-26 DK DK19764330.7T patent/DK3762385T3/da active
- 2019-02-26 KR KR1020207028226A patent/KR102810102B1/ko active Active
- 2019-02-26 HR HRP20250517TT patent/HRP20250517T1/hr unknown
- 2019-02-26 FI FIEP19764330.7T patent/FI3762385T3/fi active
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