JP2021501781A5 - - Google Patents

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Publication number
JP2021501781A5
JP2021501781A5 JP2020524777A JP2020524777A JP2021501781A5 JP 2021501781 A5 JP2021501781 A5 JP 2021501781A5 JP 2020524777 A JP2020524777 A JP 2020524777A JP 2020524777 A JP2020524777 A JP 2020524777A JP 2021501781 A5 JP2021501781 A5 JP 2021501781A5
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JP
Japan
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alkyl
formula
compound
halo
group
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Pending
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JP2020524777A
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English (en)
Japanese (ja)
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JP2021501781A (ja
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Priority claimed from PCT/US2018/058963 external-priority patent/WO2019090081A1/en
Publication of JP2021501781A publication Critical patent/JP2021501781A/ja
Publication of JP2021501781A5 publication Critical patent/JP2021501781A5/ja
Pending legal-status Critical Current

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JP2020524777A 2017-11-02 2018-11-02 統合的ストレス経路の調節剤 Pending JP2021501781A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762580776P 2017-11-02 2017-11-02
US62/580,776 2017-11-02
US201862643071P 2018-03-14 2018-03-14
US62/643,071 2018-03-14
PCT/US2018/058963 WO2019090081A1 (en) 2017-11-02 2018-11-02 Modulators of the integrated stress pathway

Publications (2)

Publication Number Publication Date
JP2021501781A JP2021501781A (ja) 2021-01-21
JP2021501781A5 true JP2021501781A5 (https=) 2021-12-09

Family

ID=64650479

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020524777A Pending JP2021501781A (ja) 2017-11-02 2018-11-02 統合的ストレス経路の調節剤

Country Status (12)

Country Link
US (1) US20200347033A1 (https=)
EP (1) EP3704091B1 (https=)
JP (1) JP2021501781A (https=)
KR (1) KR20200096523A (https=)
CN (1) CN112218851A (https=)
AU (2) AU2018360850A1 (https=)
BR (1) BR112020008833A2 (https=)
CA (1) CA3080959A1 (https=)
IL (1) IL274406B2 (https=)
MX (1) MX2020004534A (https=)
SG (1) SG11202004009TA (https=)
WO (1) WO2019090081A1 (https=)

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JP2020522553A (ja) * 2017-06-07 2020-07-30 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Atf4経路阻害剤としての化合物
CA3071024A1 (en) 2017-08-09 2019-02-14 Denali Therapeutics Inc. Compounds, compositions and methods
CN111201245B (zh) 2017-09-01 2024-04-05 戴纳立制药公司 化合物、组合物和方法
WO2019090088A1 (en) 2017-11-02 2019-05-09 Calico Life Sciences Llc Modulators of the integrated stress pathway
CN111757739A (zh) 2017-12-13 2020-10-09 普拉西斯生物技术有限责任公司 整合应激反应路径抑制剂
AU2019282253A1 (en) 2018-06-05 2020-11-26 Altos Labs, Inc. Inhibitors of integrated stress response pathway
TW202545902A (zh) 2018-10-11 2025-12-01 美商嘉來克生命科學有限責任公司 整合應激路徑之前藥調節劑
EP3924341A4 (en) 2019-02-13 2022-11-02 Denali Therapeutics Inc. Compounds, compositions and methods
SG11202108552QA (en) 2019-02-13 2021-09-29 Denali Therapeutics Inc Compounds, compositions and methods
MX2021012904A (es) 2019-04-23 2022-01-18 Evotec Int Gmbh Moduladores de la via de respuesta al estres integrada.
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WO2020252207A1 (en) 2019-06-12 2020-12-17 Praxis Biotech LLC Modulators of integrated stress response pathway
JP7699595B2 (ja) 2020-01-28 2025-06-27 エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 統合的ストレス応答経路の調節因子
CN115190813B (zh) * 2020-03-11 2024-10-15 埃沃特克国际有限责任公司 整合应激反应途径的调节剂
EP4232153A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
EP4232447A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
RS66455B1 (sr) 2020-10-22 2025-02-28 Evotec Int Gmbh Modulatori puta integrisanog odgovora na stres
CN116768877B (zh) * 2022-05-30 2026-03-31 中国药科大学 Isr抑制剂及其制备方法和应用

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