JP2023508142A5 - - Google Patents
Info
- Publication number
- JP2023508142A5 JP2023508142A5 JP2022538727A JP2022538727A JP2023508142A5 JP 2023508142 A5 JP2023508142 A5 JP 2023508142A5 JP 2022538727 A JP2022538727 A JP 2022538727A JP 2022538727 A JP2022538727 A JP 2022538727A JP 2023508142 A5 JP2023508142 A5 JP 2023508142A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- acrylic acid
- oxadiazole
- phenyl
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025077120A JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19219531.1 | 2019-12-23 | ||
| EP19219531 | 2019-12-23 | ||
| EP20162545.6 | 2020-03-11 | ||
| EP20162545 | 2020-03-11 | ||
| EP20189623 | 2020-08-05 | ||
| EP20189623.0 | 2020-08-05 | ||
| EP20205768 | 2020-11-04 | ||
| EP20205768.3 | 2020-11-04 | ||
| PCT/GB2020/053357 WO2021130492A1 (en) | 2019-12-23 | 2020-12-23 | Carboxy derivatives with antiinflammatory properties |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077120A Division JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023508142A JP2023508142A (ja) | 2023-03-01 |
| JP2023508142A5 true JP2023508142A5 (https=) | 2023-12-22 |
| JP7679384B2 JP7679384B2 (ja) | 2025-05-19 |
Family
ID=74104118
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022538727A Active JP7679384B2 (ja) | 2019-12-23 | 2020-12-23 | 抗炎症特性を有するカルボン酸誘導体 |
| JP2025077120A Pending JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025077120A Pending JP2025131581A (ja) | 2019-12-23 | 2025-05-07 | 抗炎症特性を有するカルボン酸誘導体 |
Country Status (29)
| Country | Link |
|---|---|
| EP (2) | EP4081511B3 (https=) |
| JP (2) | JP7679384B2 (https=) |
| KR (1) | KR20220119425A (https=) |
| CN (1) | CN115066418B (https=) |
| AU (1) | AU2020412853A1 (https=) |
| BR (1) | BR112022011933A2 (https=) |
| CA (2) | CA3161424C (https=) |
| CL (1) | CL2022001722A1 (https=) |
| CO (1) | CO2022008652A2 (https=) |
| CR (1) | CR20220300A (https=) |
| DK (1) | DK4081511T3 (https=) |
| EC (1) | ECSP22049370A (https=) |
| ES (1) | ES2987014T3 (https=) |
| FI (1) | FI4081511T3 (https=) |
| HR (1) | HRP20241378T1 (https=) |
| HU (1) | HUE068571T2 (https=) |
| IL (1) | IL293982B2 (https=) |
| JO (1) | JOP20220162A1 (https=) |
| LT (1) | LT4081511T (https=) |
| MA (1) | MA58170B1 (https=) |
| MD (1) | MD4081511T2 (https=) |
| MX (1) | MX2022007846A (https=) |
| PE (1) | PE20221584A1 (https=) |
| PH (1) | PH12022551546A1 (https=) |
| PL (1) | PL4081511T4 (https=) |
| RS (1) | RS66019B1 (https=) |
| SI (1) | SI4081511T1 (https=) |
| TW (1) | TWI891696B (https=) |
| WO (1) | WO2021130492A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021013299A (es) | 2019-04-30 | 2022-01-31 | Sitryx Therapeutics Ltd | Derivados de acido itaconico y usos de estos en el tratamiento de una enfermedad inflamatoria asociada con una respuesta inmunitaria indeseable. |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| EP4192821A1 (en) | 2020-08-05 | 2023-06-14 | Sitryx Therapeutics Limited | Alpha,beta unsaturated methacrylic esters with anti-inflammatory properties |
| EP4330231A1 (en) * | 2021-04-26 | 2024-03-06 | Sitryx Therapeutics Limited | 2-methylene-4-oxo-butanoic acid drivatives for the treatment of inflammation |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を治療するための方法 |
| EP4359390A1 (en) * | 2021-06-22 | 2024-05-01 | Sitryx Therapeutics Limited | Acrylamide derivatives useful as anti-inflammatory agents |
| CN113499453B (zh) * | 2021-07-20 | 2022-10-21 | 徐州医科大学 | 自噬抑制及抗炎联合温合光热诊疗剂及其制备方法与应用 |
| US20240360067A1 (en) | 2021-08-11 | 2024-10-31 | Sitryx Therapeutics Limited | Derivatives of itaconic acid and their use as anti-inflammatory agents |
| AU2023287566A1 (en) | 2022-06-22 | 2025-01-16 | Sitryx Therapeutics Limited | Oxadiazole derivatives, preparation process thereof and their use in treating inflammatory diseases |
| WO2024089421A1 (en) | 2022-10-25 | 2024-05-02 | Sitryx Therapeutics Limited | Tetrazole derivatives |
| CN120712258A (zh) | 2022-12-15 | 2025-09-26 | 西特瑞治疗有限公司 | 用于治疗或预防炎性疾病或与不良免疫反应相关的疾病的取代吡啶类化合物 |
| KR102864655B1 (ko) * | 2023-01-19 | 2025-09-29 | 대한민국 | 뎅기바이러스 감염에 의한 질환의 예방 또는 치료용 약학적 조성물 |
| CN115819186B (zh) * | 2023-02-14 | 2023-05-16 | 广东银珠医药科技有限公司 | 一种3,5-二氯苯甲醇的新型制备方法 |
| CN117205194A (zh) * | 2023-05-10 | 2023-12-12 | 苏州大学 | 衣康酸或其衍生物在制备预防或治疗急性移植物抗宿主病药物中的应用 |
| CN116725998A (zh) * | 2023-07-20 | 2023-09-12 | 中国科学技术大学 | 特立氟胺在抑制nlrp3炎症小体活化中的应用 |
| CN119792264B (zh) * | 2025-03-14 | 2025-06-10 | 华中科技大学同济医学院附属同济医院 | 丁酰肼在制备预防或治疗copd的药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995011235A1 (en) * | 1993-10-20 | 1995-04-27 | The Upjohn Company | Pyrimidinones as antiarthritic and anti-inflammatories |
| US6566384B1 (en) * | 1996-08-07 | 2003-05-20 | Darwin Discovery Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| TW201206429A (en) * | 2010-07-08 | 2012-02-16 | Merck Serono Sa | Substituted oxadiazole derivatives |
| KR101861883B1 (ko) * | 2010-12-06 | 2018-05-28 | 글락소 그룹 리미티드 | Lp-PLA₂에 의해 매개되는 질환 또는 상태의 치료에 사용하기 위한 피리미디논 화합물 |
| KR102085557B1 (ko) | 2013-03-14 | 2020-03-06 | 엘커메스 파마 아일랜드 리미티드 | 푸마레이트의 프로드럭 및 다양한 질환을 치료하는데 있어서의 이들의 용도 |
| WO2014152263A1 (en) * | 2013-03-15 | 2014-09-25 | Karyopharm Therapeutics Inc. | Exo olefin-containing nuclear transport modulators and uses thereof |
| AU2014290368B2 (en) * | 2013-07-18 | 2019-07-11 | Baylor College Of Medicine | Methods and compositions for treatment of muscle wasting, muscle weakness, and/or cachexia |
| CN103923105B (zh) * | 2014-04-17 | 2016-08-24 | 北京大学 | 2-中氮茚甲酰胺类化合物及其制备和用途 |
| EP3416634A4 (en) | 2016-02-15 | 2019-10-09 | Artyomov, Maxim | IMMUNOMODULATORY AGENTS AND METHOD FOR USE THEREOF |
| WO2019036509A1 (en) | 2017-08-14 | 2019-02-21 | Washington University | METHODS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH CANCER, INFLAMMATION OR IMMUNE RESPONSE |
| CN110731955B (zh) | 2019-10-28 | 2023-05-02 | 中山大学 | 衣康酸二甲酯在预防和治疗溃疡性结肠炎及其癌变中的应用 |
-
2020
- 2020-12-23 MX MX2022007846A patent/MX2022007846A/es unknown
- 2020-12-23 EP EP20830293.5A patent/EP4081511B3/en active Active
- 2020-12-23 CR CR20220300A patent/CR20220300A/es unknown
- 2020-12-23 TW TW109145642A patent/TWI891696B/zh active
- 2020-12-23 LT LTEPPCT/GB2020/053357T patent/LT4081511T/lt unknown
- 2020-12-23 CA CA3161424A patent/CA3161424C/en active Active
- 2020-12-23 PH PH1/2022/551546A patent/PH12022551546A1/en unknown
- 2020-12-23 MD MDE20221214T patent/MD4081511T2/ro unknown
- 2020-12-23 MA MA58170A patent/MA58170B1/fr unknown
- 2020-12-23 AU AU2020412853A patent/AU2020412853A1/en active Pending
- 2020-12-23 JP JP2022538727A patent/JP7679384B2/ja active Active
- 2020-12-23 SI SI202030480T patent/SI4081511T1/sl unknown
- 2020-12-23 IL IL293982A patent/IL293982B2/en unknown
- 2020-12-23 DK DK20830293.5T patent/DK4081511T3/da active
- 2020-12-23 KR KR1020227024819A patent/KR20220119425A/ko active Pending
- 2020-12-23 CN CN202080083315.0A patent/CN115066418B/zh active Active
- 2020-12-23 RS RS20241087A patent/RS66019B1/sr unknown
- 2020-12-23 PE PE2022001159A patent/PE20221584A1/es unknown
- 2020-12-23 HU HUE20830293A patent/HUE068571T2/hu unknown
- 2020-12-23 EP EP24183456.3A patent/EP4442319A3/en not_active Withdrawn
- 2020-12-23 ES ES20830293T patent/ES2987014T3/es active Active
- 2020-12-23 CA CA3280359A patent/CA3280359A1/en active Pending
- 2020-12-23 FI FIEP20830293.5T patent/FI4081511T3/fi active
- 2020-12-23 WO PCT/GB2020/053357 patent/WO2021130492A1/en not_active Ceased
- 2020-12-23 BR BR112022011933A patent/BR112022011933A2/pt unknown
- 2020-12-23 HR HRP20241378TT patent/HRP20241378T1/hr unknown
- 2020-12-23 PL PL20830293.5T patent/PL4081511T4/pl unknown
-
2022
- 2022-06-21 CO CONC2022/0008652A patent/CO2022008652A2/es unknown
- 2022-06-21 EC ECSENADI202249370A patent/ECSP22049370A/es unknown
- 2022-06-21 JO JOP/2022/0162A patent/JOP20220162A1/ar unknown
- 2022-06-22 CL CL2022001722A patent/CL2022001722A1/es unknown
-
2025
- 2025-05-07 JP JP2025077120A patent/JP2025131581A/ja active Pending
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