JP2024506904A5 - - Google Patents
Info
- Publication number
- JP2024506904A5 JP2024506904A5 JP2023548654A JP2023548654A JP2024506904A5 JP 2024506904 A5 JP2024506904 A5 JP 2024506904A5 JP 2023548654 A JP2023548654 A JP 2023548654A JP 2023548654 A JP2023548654 A JP 2023548654A JP 2024506904 A5 JP2024506904 A5 JP 2024506904A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrimidine
- pyrrolidine
- carboxylic acid
- methylbenzofl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163148201P | 2021-02-11 | 2021-02-11 | |
| US63/148,201 | 2021-02-11 | ||
| PCT/US2022/016073 WO2022174012A1 (en) | 2021-02-11 | 2022-02-11 | INHIBITORS OF cGAS ACTIVITY AS THERAPEUTIC AGENTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024506904A JP2024506904A (ja) | 2024-02-15 |
| JP2024506904A5 true JP2024506904A5 (https=) | 2025-02-19 |
Family
ID=82837325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023548654A Pending JP2024506904A (ja) | 2021-02-11 | 2022-02-11 | 治療剤としてのｃＧＡＳ活性の阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240174684A1 (https=) |
| EP (1) | EP4291188A4 (https=) |
| JP (1) | JP2024506904A (https=) |
| KR (1) | KR20230144550A (https=) |
| CN (1) | CN116997339A (https=) |
| AU (1) | AU2022218787A1 (https=) |
| CA (1) | CA3206520A1 (https=) |
| WO (1) | WO2022174012A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119119063A (zh) | 2021-05-12 | 2024-12-13 | 勃林格殷格翰国际有限公司 | 作为cGAS抑制剂的具有N-连接环状取代基的吡啶衍生物 |
| WO2022238335A1 (en) * | 2021-05-12 | 2022-11-17 | Boehringer Ingelheim International Gmbh | Pyridine derivatives with c-linked cyclic substituents as cgas inhibitors |
| JP2025528113A (ja) * | 2022-08-10 | 2025-08-26 | ベルブルック ラボズ，エルエルシー | 治療剤としてのｃＧＡＳ活性の阻害剤 |
| KR20250103719A (ko) * | 2022-11-09 | 2025-07-07 | 베링거 인겔하임 인터내셔날 게엠베하 | cGAS 억제제로서의 사이클릭 벤즈이미다졸 유도체 |
| AU2023376006A1 (en) * | 2022-11-09 | 2025-03-13 | Boehringer Ingelheim International Gmbh | Cyclic pyridine derivatives as cgas inhibitors |
| WO2025233174A1 (en) | 2024-05-08 | 2025-11-13 | Boehringer Ingelheim International Gmbh | Benzimidazole derivatives as cgas inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090028819A (ko) * | 2006-07-11 | 2009-03-19 | 얀센 파마슈티카 엔.브이. | 히스타민 ｈ４ 수용체의 벤조푸로- 및 벤조티에노피리미딘 조절제 |
| WO2008074445A1 (en) * | 2006-12-18 | 2008-06-26 | Ucb Pharma, S.A. | Novel tricyclic and heterotricyclic derivatives, processes for preparing them, pharmaceutical compositions thereof |
| WO2013115167A1 (ja) * | 2012-01-31 | 2013-08-08 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | アムバチニブ誘導体 |
| EP3565810A1 (en) * | 2017-01-03 | 2019-11-13 | ViiV Healthcare UK (No.5) Limited | Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication |
| CA3125625A1 (en) * | 2019-01-04 | 2020-07-09 | Bellbrook Labs, Llc | Inhibitors of cgas activity as therapeutic agents |
-
2022
- 2022-02-11 US US18/275,190 patent/US20240174684A1/en active Pending
- 2022-02-11 CA CA3206520A patent/CA3206520A1/en active Pending
- 2022-02-11 KR KR1020237028625A patent/KR20230144550A/ko active Pending
- 2022-02-11 AU AU2022218787A patent/AU2022218787A1/en not_active Abandoned
- 2022-02-11 EP EP22753392.4A patent/EP4291188A4/en active Pending
- 2022-02-11 WO PCT/US2022/016073 patent/WO2022174012A1/en not_active Ceased
- 2022-02-11 CN CN202280019484.7A patent/CN116997339A/zh active Pending
- 2022-02-11 JP JP2023548654A patent/JP2024506904A/ja active Pending
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