JP2020528907A5 - - Google Patents
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- JP2020528907A5 JP2020528907A5 JP2020504026A JP2020504026A JP2020528907A5 JP 2020528907 A5 JP2020528907 A5 JP 2020528907A5 JP 2020504026 A JP2020504026 A JP 2020504026A JP 2020504026 A JP2020504026 A JP 2020504026A JP 2020528907 A5 JP2020528907 A5 JP 2020528907A5
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- alkyl
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- nhc
- pharmaceutically acceptable
- acceptable salt
- Prior art date
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- NERXPXBELDBEPZ-RMKNXTFCSA-N (e)-n-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide Chemical compound C=12C=C(NC(=O)\C=C\CN(C)C)C(OCC)=CC2=NC=C(C#N)C=1NC(C=C1Cl)=CC=C1OCC1=CC=CC(F)=C1 NERXPXBELDBEPZ-RMKNXTFCSA-N 0.000 claims 1
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023016586A JP7554300B2 (ja) | 2017-07-28 | 2023-02-07 | 大環式化合物およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762538193P | 2017-07-28 | 2017-07-28 | |
| US62/538,193 | 2017-07-28 | ||
| US201862700990P | 2018-07-20 | 2018-07-20 | |
| US62/700,990 | 2018-07-20 | ||
| PCT/US2018/043817 WO2019023417A1 (en) | 2017-07-28 | 2018-07-26 | MACROCYCLIC COMPOUNDS AND USES THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023016586A Division JP7554300B2 (ja) | 2017-07-28 | 2023-02-07 | 大環式化合物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020528907A JP2020528907A (ja) | 2020-10-01 |
| JP2020528907A5 true JP2020528907A5 (enExample) | 2021-09-02 |
| JP7224334B2 JP7224334B2 (ja) | 2023-02-17 |
Family
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Family Applications (2)
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| JP2020504026A Active JP7224334B2 (ja) | 2017-07-28 | 2018-07-26 | 大環式化合物およびその使用 |
| JP2023016586A Active JP7554300B2 (ja) | 2017-07-28 | 2023-02-07 | 大環式化合物およびその使用 |
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| JP2023016586A Active JP7554300B2 (ja) | 2017-07-28 | 2023-02-07 | 大環式化合物およびその使用 |
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| PH (1) | PH12020500033A1 (enExample) |
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Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20191283T1 (hr) | 2014-01-24 | 2019-10-18 | Turning Point Therapeutics, Inc. | Diaril makrocikli kao modulatori protein kinaze |
| AU2016287568B2 (en) | 2015-07-02 | 2020-08-20 | Turning Point Therapeutics, Inc. | Chiral diaryl macrocycles as modulators of protein kinases |
| DK3325488T3 (da) | 2015-07-21 | 2020-09-14 | Turning Point Therapeutics Inc | Chiral diaryl-makrocyklus og anvendelse deraf til behandling af cancer |
| TW201815799A (zh) | 2016-07-28 | 2018-05-01 | 美商Ｔｐ生物醫藥公司 | 巨環激酶抑制劑 |
| TWI808958B (zh) | 2017-01-25 | 2023-07-21 | 美商特普醫葯公司 | 涉及二芳基巨環化合物之組合療法 |
| BR112020001695A2 (pt) * | 2017-07-28 | 2020-07-21 | Turning Point Therapeutics, Inc. | compostos macrocíclicos e usos dos mesmos |
| CN109516999B (zh) * | 2017-11-01 | 2021-08-17 | 郑州泰基鸿诺医药股份有限公司 | 用作蛋白质激酶调节剂的化合物及其应用 |
| CN111511746B (zh) | 2017-12-19 | 2024-01-09 | 特普医药公司 | 用于治疗疾病的巨环化合物 |
| JP7128345B2 (ja) | 2018-04-25 | 2022-08-30 | プライムジーン（ベイジン）カンパニー リミテッド | ジアリール大員環化合物、医薬組成物及びその用途 |
| DK3870579T3 (da) | 2018-10-22 | 2025-01-02 | Alumis Inc | Tyk2-inhibitorer og anvendelser deraf |
| JP7586829B2 (ja) * | 2019-03-11 | 2024-11-19 | アルミス インコーポレイテッド | Ｔｙｋ２阻害剤およびその使用 |
| WO2020233645A1 (zh) | 2019-05-21 | 2020-11-26 | 浙江海正药业股份有限公司 | 大环类衍生物、及其制备方法和用途 |
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