JP2020188756A5 - - Google Patents

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Publication number
JP2020188756A5
JP2020188756A5 JP2020075777A JP2020075777A JP2020188756A5 JP 2020188756 A5 JP2020188756 A5 JP 2020188756A5 JP 2020075777 A JP2020075777 A JP 2020075777A JP 2020075777 A JP2020075777 A JP 2020075777A JP 2020188756 A5 JP2020188756 A5 JP 2020188756A5
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Japan
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nucleotides
modified
dsrna agent
agent according
nucleotide
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JP2020075777A
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Japanese (ja)
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JP7530204B2 (ja
JP2020188756A (ja
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Priority claimed from JP2017557175A external-priority patent/JP6695902B2/ja
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Publication of JP2020188756A5 publication Critical patent/JP2020188756A5/ja
Priority to JP2022106599A priority Critical patent/JP2022141707A/ja
Priority to JP2023209185A priority patent/JP2024037849A/ja
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JP2020075777A 2015-05-06 2020-04-22 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法 Active JP7530204B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022106599A JP2022141707A (ja) 2015-05-06 2022-06-30 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法
JP2023209185A JP2024037849A (ja) 2015-05-06 2023-12-12 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562157890P 2015-05-06 2015-05-06
US62/157,890 2015-05-06
US201562260887P 2015-11-30 2015-11-30
US62/260,887 2015-11-30
US201562266958P 2015-12-14 2015-12-14
US62/266,958 2015-12-14
JP2017557175A JP6695902B2 (ja) 2015-05-06 2016-05-05 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Related Parent Applications (1)

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JP2017557175A Division JP6695902B2 (ja) 2015-05-06 2016-05-05 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Related Child Applications (1)

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JP2022106599A Division JP2022141707A (ja) 2015-05-06 2022-06-30 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Publications (3)

Publication Number Publication Date
JP2020188756A JP2020188756A (ja) 2020-11-26
JP2020188756A5 true JP2020188756A5 (enExample) 2021-01-21
JP7530204B2 JP7530204B2 (ja) 2024-08-07

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Family Applications (4)

Application Number Title Priority Date Filing Date
JP2017557175A Active JP6695902B2 (ja) 2015-05-06 2016-05-05 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法
JP2020075777A Active JP7530204B2 (ja) 2015-05-06 2020-04-22 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法
JP2022106599A Pending JP2022141707A (ja) 2015-05-06 2022-06-30 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法
JP2023209185A Pending JP2024037849A (ja) 2015-05-06 2023-12-12 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2017557175A Active JP6695902B2 (ja) 2015-05-06 2016-05-05 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022106599A Pending JP2022141707A (ja) 2015-05-06 2022-06-30 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法
JP2023209185A Pending JP2024037849A (ja) 2015-05-06 2023-12-12 第ＸＩＩ因子（ハーゲマン因子）（Ｆ１２）、カリクレインＢ、血漿（フレッチャー因子）１（ＫＬＫＢ１）、及びキニノーゲン１（ＫＮＧ１）ｉＲＮＡ組成物及びその使用方法

Country Status (13)

Country Link
US (4) US20180100150A1 (enExample)
EP (1) EP3292201A2 (enExample)
JP (4) JP6695902B2 (enExample)
KR (2) KR20250107273A (enExample)
CN (2) CN108271386B (enExample)
AU (2) AU2016257996A1 (enExample)
BR (1) BR112017021967A2 (enExample)
CA (1) CA2984636A1 (enExample)
EA (1) EA201792444A1 (enExample)
HK (1) HK1249920A1 (enExample)
TW (4) TWI806034B (enExample)
UY (2) UY40330A (enExample)
WO (1) WO2016179342A2 (enExample)

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CN111655297A (zh) 2018-09-30 2020-09-11 苏州瑞博生物技术有限公司 一种siRNA缀合物及其制备方法和用途
CN118562796A (zh) * 2019-01-18 2024-08-30 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
EP3974529A4 (en) * 2019-05-22 2024-02-07 Suzhou Ribo Life Science Co., Ltd. NUCLEIC ACID, PHARMACEUTICAL COMPOSITION, CONJUGATE, PROCESS OF PREPARATION AND USE
CN113891939B (zh) * 2019-05-24 2024-04-02 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
CN115362256A (zh) * 2020-02-07 2022-11-18 因特利亚治疗公司 用于激肽释放酶（klkb1）基因编辑的组合物和方法
US20230126881A1 (en) * 2020-03-27 2023-04-27 Alnylam Pharmaceuticals, Inc. Fc FRAGMENT OF IgG RECEPTOR AND TRANSPORTER (FCGRT) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
TW202242111A (zh) 2020-12-18 2022-11-01 美商Ionis製藥公司 用於調節因子ｘｉｉ之化合物及方法
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TW202346586A (zh) * 2022-01-28 2023-12-01 大陸商上海舶望製藥有限公司 用於抑制前激肽釋放酶（pkk）蛋白表達的組合物和方法
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CA3228733A1 (en) 2021-08-13 2023-02-16 Alnylam Pharmaceuticals, Inc. Factor xii (f12) irna compositions and methods of use thereof

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