KR102827366B1 - 인자 ＸＩＩ(하게만 인자)(Ｆ12), 칼리크레인 Ｂ, 혈장(플레처 인자) 1(ＫＬＫＢ1) 및 키니노겐 1(ＫＮＧ1) ｉＲＮＡ 조성물 및 그의 이용 방법 - Google Patents

인자 ＸＩＩ(하게만 인자)(Ｆ12), 칼리크레인 Ｂ, 혈장(플레처 인자) 1(ＫＬＫＢ1) 및 키니노겐 1(ＫＮＧ1) ｉＲＮＡ 조성물 및 그의 이용 방법 Download PDF

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KR102827366B1
KR102827366B1 KR1020177033031A KR20177033031A KR102827366B1 KR 102827366 B1 KR102827366 B1 KR 102827366B1 KR 1020177033031 A KR1020177033031 A KR 1020177033031A KR 20177033031 A KR20177033031 A KR 20177033031A KR 102827366 B1 KR102827366 B1 KR 102827366B1
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애킨 애킨크
그레고리 힌클
마틴 마이어
제임스 버틀러
징쑤언 리우
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알닐람 파마슈티칼스 인코포레이티드
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KR1020177033031A 2015-05-06 2016-05-05 인자 ＸＩＩ(하게만 인자)(Ｆ12), 칼리크레인 Ｂ, 혈장(플레처 인자) 1(ＫＬＫＢ1) 및 키니노겐 1(ＫＮＧ1) ｉＲＮＡ 조성물 및 그의 이용 방법 Active KR102827366B1 (ko)

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KR1020257020838A KR20250107273A (ko) 2015-05-06 2016-05-05 인자 ＸＩＩ(하게만 인자)(Ｆ12), 칼리크레인 Ｂ, 혈장(플레처 인자) 1(ＫＬＫＢ1) 및 키니노겐 1(ＫＮＧ1) ｉＲＮＡ 조성물 및 그의 이용 방법

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562157890P 2015-05-06 2015-05-06
US62/157,890 2015-05-06
US201562260887P 2015-11-30 2015-11-30
US62/260,887 2015-11-30
US201562266958P 2015-12-14 2015-12-14
US62/266,958 2015-12-14
PCT/US2016/030876 WO2016179342A2 (en) 2015-05-06 2016-05-05 Factor xii (hageman factor) (f12), kallikrein b, plasma (fletcher factor) 1 (klkb1), and kininogen 1 (kng1) irna compositions and methods of use thereof

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KR102827366B1 true KR102827366B1 (ko) 2025-07-03

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KR1020177033031A Active KR102827366B1 (ko) 2015-05-06 2016-05-05 인자 ＸＩＩ(하게만 인자)(Ｆ12), 칼리크레인 Ｂ, 혈장(플레처 인자) 1(ＫＬＫＢ1) 및 키니노겐 1(ＫＮＧ1) ｉＲＮＡ 조성물 및 그의 이용 방법

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US (4) US20180100150A1 (enExample)
EP (1) EP3292201A2 (enExample)
JP (4) JP6695902B2 (enExample)
KR (2) KR20250107273A (enExample)
CN (2) CN108271386B (enExample)
AU (2) AU2016257996A1 (enExample)
BR (1) BR112017021967A2 (enExample)
CA (1) CA2984636A1 (enExample)
EA (1) EA201792444A1 (enExample)
HK (1) HK1249920A1 (enExample)
TW (4) TWI806034B (enExample)
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KR20250145702A (ko) 2017-04-11 2025-10-13 아뷰터스 바이오파마 코포레이션 표적화 조성물
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KR102834361B1 (ko) 2017-12-01 2025-07-17 쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 핵산, 이를 포함하는 조성물과 컨쥬게이트, 및 그의 제조 방법과 용도
JP7365052B2 (ja) 2017-12-01 2023-10-19 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
US11414661B2 (en) 2017-12-01 2022-08-16 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof
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CN113891939B (zh) * 2019-05-24 2024-04-02 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
CN115362256A (zh) * 2020-02-07 2022-11-18 因特利亚治疗公司 用于激肽释放酶（klkb1）基因编辑的组合物和方法
US20230126881A1 (en) * 2020-03-27 2023-04-27 Alnylam Pharmaceuticals, Inc. Fc FRAGMENT OF IgG RECEPTOR AND TRANSPORTER (FCGRT) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
TW202242111A (zh) 2020-12-18 2022-11-01 美商Ionis製藥公司 用於調節因子ｘｉｉ之化合物及方法
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