JP2019531055A5 - - Google Patents
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- JP2019531055A5 JP2019531055A5 JP2019505354A JP2019505354A JP2019531055A5 JP 2019531055 A5 JP2019531055 A5 JP 2019531055A5 JP 2019505354 A JP2019505354 A JP 2019505354A JP 2019505354 A JP2019505354 A JP 2019505354A JP 2019531055 A5 JP2019531055 A5 JP 2019531055A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- binding protein
- isoleucine
- binding
- immunoglobulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022112299A JP2022160444A (ja) | 2016-08-11 | 2022-07-13 | アルカリ安定性免疫グロブリン結合タンパク質 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16183710 | 2016-08-11 | ||
| EP16183710.9 | 2016-08-11 | ||
| EP16205707 | 2016-12-21 | ||
| EP16205707.9 | 2016-12-21 | ||
| PCT/EP2017/069976 WO2018029157A1 (en) | 2016-08-11 | 2017-08-07 | Novel alkaline stable immunoglobulin-binding proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022112299A Division JP2022160444A (ja) | 2016-08-11 | 2022-07-13 | アルカリ安定性免疫グロブリン結合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019531055A JP2019531055A (ja) | 2019-10-31 |
| JP2019531055A5 true JP2019531055A5 (enExample) | 2020-08-13 |
| JP7181612B2 JP7181612B2 (ja) | 2022-12-01 |
Family
ID=59631752
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019507171A Active JP6951417B2 (ja) | 2016-08-11 | 2017-08-07 | アフィニティークロマトグラフィーのためのＦＣ−結合タンパク質、並びにＦｃ−結合タンパク質を含むアフィニティー分離マトリックスおよびその使用 |
| JP2019505354A Active JP7181612B2 (ja) | 2016-08-11 | 2017-08-07 | アルカリ安定性免疫グロブリン結合タンパク質 |
| JP2022112299A Pending JP2022160444A (ja) | 2016-08-11 | 2022-07-13 | アルカリ安定性免疫グロブリン結合タンパク質 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019507171A Active JP6951417B2 (ja) | 2016-08-11 | 2017-08-07 | アフィニティークロマトグラフィーのためのＦＣ−結合タンパク質、並びにＦｃ−結合タンパク質を含むアフィニティー分離マトリックスおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022112299A Pending JP2022160444A (ja) | 2016-08-11 | 2022-07-13 | アルカリ安定性免疫グロブリン結合タンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US11014967B2 (enExample) |
| EP (4) | EP4177260A1 (enExample) |
| JP (3) | JP6951417B2 (enExample) |
| KR (3) | KR20230133943A (enExample) |
| CN (4) | CN117736281A (enExample) |
| AU (2) | AU2017311542B2 (enExample) |
| CA (2) | CA3030208A1 (enExample) |
| DK (1) | DK3497117T5 (enExample) |
| LT (1) | LT3497117T (enExample) |
| SG (1) | SG11201901066UA (enExample) |
| WO (2) | WO2018029158A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3253785B1 (en) | 2015-02-06 | 2019-04-10 | Navigo Proteins Gmbh | Novel egfr binding proteins |
| CN107922483B (zh) | 2015-07-16 | 2021-07-30 | 纳维格蛋白质有限公司 | 新型免疫球蛋白结合蛋白及其在亲和纯化中的用途 |
| WO2017013136A1 (en) | 2015-07-20 | 2017-01-26 | Scil Proteins Gmbh | Novel binding proteins based on di-ubiquitin muteins and methods for generation |
| AU2017260274A1 (en) | 2016-05-04 | 2018-11-01 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
| CA3030208A1 (en) * | 2016-08-11 | 2018-02-15 | Navigo Proteins Gmbh | Novel alkaline stable immunoglobulin binding proteins |
| WO2019030156A1 (en) | 2017-08-07 | 2019-02-14 | Repligen Corporation | FC BINDING PROTEINS WITH CYSTEINE IN THE C-TERMINAL HELICAL REGION |
| EP3546476A1 (en) * | 2018-03-26 | 2019-10-02 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| US11414466B2 (en) | 2017-11-07 | 2022-08-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer |
| EP4249097A3 (en) | 2018-02-01 | 2024-01-10 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| AU2019380620B2 (en) * | 2018-11-12 | 2022-05-26 | Navigo Proteins Gmbh | Novel triple-helical polypeptides lacking binding affinity for the Fc domain of immunoglobulin and uses thereof |
| EP3650465A1 (en) | 2018-11-12 | 2020-05-13 | Navigo Proteins Gmbh | Novel populations of polypeptides having a triple-helical structure |
| CA3123986A1 (en) | 2018-12-18 | 2020-06-25 | Navigo Proteins Gmbh | Novel folr1 specific binding proteins for cancer diagnosis and treatment |
| BR112021013026A2 (pt) * | 2019-02-01 | 2021-10-13 | Navigo Proteins Gmbh | Proteínas de ligação à imunoglobulina, matriz de separação por afinidade, uso da proteína de ligação à imunoglobulina, e método de purificação por afinidade de uma proteína compreendendo uma sequência de imunoglobulina |
| GB201904125D0 (en) | 2019-03-26 | 2019-05-08 | Ge Healthcare Bio Sciences Ab | Method for sanitization of a chromatography column |
| JP7432813B2 (ja) * | 2019-09-10 | 2024-02-19 | 東ソー株式会社 | 免疫グロブリン結合性タンパク質 |
| US12286458B2 (en) | 2019-12-17 | 2025-04-29 | Navigo Proteins Gmbh | Binding proteins for the enzyme acid alpha glucosidase (GAA) and uses thereof |
| WO2021165395A1 (en) * | 2020-02-21 | 2021-08-26 | Navigo Proteins Gmbh | Affinity ligand for the soluble part of fibroblast growth factor receptor 3 (sfgfr3) |
| EP3875472A1 (en) | 2020-03-06 | 2021-09-08 | Navigo Proteins Gmbh | Novel immunoglobulin binding polypeptides |
| WO2021260052A1 (en) * | 2020-06-23 | 2021-12-30 | Navigo Proteins Gmbh | Binding protein specific for the spike protein of severe acute respiratory syndrome corona virus 2 (sars-cov-2) |
| LT4132943T (lt) * | 2020-07-15 | 2024-07-25 | Navigo Proteins Gmbh | Imunoglobulinus surišantys baltymai, skirti giminingumu pagrįstam gryninimui |
| US20230416345A1 (en) * | 2020-11-09 | 2023-12-28 | Navigo Proteins Gmbh | New type ii collagen binding proteins |
| EP4001301A1 (en) * | 2020-11-13 | 2022-05-25 | Navigo Proteins Gmbh | Binding protein for complement factor h (cfh) |
| EP4380955A1 (en) * | 2021-08-06 | 2024-06-12 | Roche Diagnostics GmbH | Chimeric igg-fc-binding ligand polypeptide and uses thereof for igg affinity purification |
| GB202113626D0 (en) | 2021-09-24 | 2021-11-10 | Cytiva Bioprocess R & D Ab | FC binding polypeptides |
| CN116925197A (zh) * | 2021-12-21 | 2023-10-24 | 百林科(兰州)新材料有限公司 | 耐碱蛋白A变体在纯化IgG抗体中的应用 |
| CN113999294B (zh) * | 2021-12-30 | 2022-03-29 | 苏州纳微科技股份有限公司 | 免疫球蛋白结合蛋白及其应用 |
| CN114409748A (zh) * | 2022-01-28 | 2022-04-29 | 博格隆(浙江)生物技术有限公司 | 蛋白a的b结构域和z结构域突变体及其应用 |
| GB202203478D0 (en) | 2022-03-14 | 2022-04-27 | Cytiva Bioprocess R & D Ab | Vh3 binding polypeptides |
| JP2025539595A (ja) * | 2022-12-16 | 2025-12-05 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | アフィニティークロマトグラフィーのための新しいリガンド |
| WO2025059162A1 (en) | 2023-09-11 | 2025-03-20 | Dana-Farber Cancer Institute, Inc. | Car-engager containing il-2 variants to enhance the functionality of car t cells |
| EP4541444A1 (en) * | 2023-10-20 | 2025-04-23 | Cytiva BioProcess R&D AB | Fusion protein for affinity capture |
| WO2025262100A1 (en) * | 2024-06-18 | 2025-12-26 | Navigo Proteins Gmbh | New ligands for the purification of antibodies via affinity chromatography |
| WO2026057420A1 (en) | 2024-09-10 | 2026-03-19 | Cytiva Bioprocess R&D Ab | Affinity ligand for purification of antibodies of isotype iga |
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| SE9103701D0 (sv) | 1991-12-13 | 1991-12-13 | Kabi Pharmacia Ab | Apolipoprotein |
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| DE69533102T2 (de) * | 1994-07-21 | 2005-06-02 | Aventis Pasteur Ltd., Toronto | Analog von haemophilus hin47 mit verminderter protease aktivität |
| WO1997012992A2 (en) | 1995-10-02 | 1997-04-10 | Royal Netherlands Academy Of Arts And Sciences | Diagnosis method for a disease caused by a frameshift mutation in a gene and reagents therefore |
| CA2235223A1 (en) | 1995-10-30 | 1997-05-09 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from heparinase i |
| US5789166A (en) | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
| GB9610967D0 (en) | 1996-05-24 | 1996-07-31 | Cambridge Antibody Tech | Specific binding members,materials and methods |
| FR2761689B1 (fr) | 1997-04-02 | 1999-06-25 | Transgene Sa | Fibre adenovirale modifiee et adenovirus cibles |
| ATE250668T1 (de) | 1997-05-28 | 2003-10-15 | Discerna Ltd | Ribosom-komplexe als selektionspartikel für die in vitro anzeige und evolution von proteinen |
| JP3614866B2 (ja) | 1997-06-12 | 2005-01-26 | リサーチ コーポレイション テクノロジーズ，インコーポレイティド | 人工抗体ポリペプチド |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| TWI259837B (en) | 1998-05-11 | 2006-08-11 | Eidgenossische Tech Hochscule | Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis |
| US20030045681A1 (en) | 1998-05-11 | 2003-03-06 | Anthony J. Zelano | Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis |
| DE19932688B4 (de) | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
| AU4243201A (en) | 2000-02-24 | 2001-09-03 | Eidgenoess Tech Hochschule | Antibody specific for the ed-b domain of fibronectin, conjugates comprising saidantibody, and their use for the detection and treatment of angiogenesis |
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| US6799121B2 (en) | 2000-03-30 | 2004-09-28 | York University | Sequencing of peptides by mass spectrometry |
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| AU2011230313B2 (en) * | 2010-03-24 | 2015-01-22 | Kaneka Corporation | Protein capable of binding specifically to immunoglobulin, and immunoglobulin-binding affinity ligand |
| EP2690173B1 (en) * | 2011-03-25 | 2019-07-03 | Kaneka Corporation | Protein for affinity-separation matrix |
| SG10201604559TA (en) | 2011-06-08 | 2016-07-28 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
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| EP2727942A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Bispecific antibodies against human EGFR, HER2, and HER3 |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
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| CN105377880B (zh) * | 2013-07-10 | 2020-08-07 | 通用电气医疗集团生物工艺研发股份公司 | 突变的免疫球蛋白结合多肽 |
| KR102236367B1 (ko) | 2013-07-26 | 2021-04-05 | 삼성전자주식회사 | DARPin을 포함하는 이중 특이 키메라 단백질 |
| US11566082B2 (en) * | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| EP3253785B1 (en) | 2015-02-06 | 2019-04-10 | Navigo Proteins Gmbh | Novel egfr binding proteins |
| DK3253795T3 (da) | 2015-02-06 | 2019-07-29 | Navigo Proteins Gmbh | Hidtil ukendte bindende proteiner, der omfatter et ubiquitin-mutein, og antistoffer eller antistoffragmenter |
| CN107922483B (zh) | 2015-07-16 | 2021-07-30 | 纳维格蛋白质有限公司 | 新型免疫球蛋白结合蛋白及其在亲和纯化中的用途 |
| JP6881760B2 (ja) | 2015-07-20 | 2021-06-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | ジユビキチン変異タンパク質に基づくＨｅｒ２結合タンパク質 |
| WO2017013136A1 (en) | 2015-07-20 | 2017-01-26 | Scil Proteins Gmbh | Novel binding proteins based on di-ubiquitin muteins and methods for generation |
| AU2017260274A1 (en) | 2016-05-04 | 2018-11-01 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
| CA3030208A1 (en) | 2016-08-11 | 2018-02-15 | Navigo Proteins Gmbh | Novel alkaline stable immunoglobulin binding proteins |
| WO2019030156A1 (en) | 2017-08-07 | 2019-02-14 | Repligen Corporation | FC BINDING PROTEINS WITH CYSTEINE IN THE C-TERMINAL HELICAL REGION |
| US11414466B2 (en) | 2017-11-07 | 2022-08-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer |
| EP4249097A3 (en) | 2018-02-01 | 2024-01-10 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
-
2017
- 2017-08-07 CA CA3030208A patent/CA3030208A1/en active Pending
- 2017-08-07 AU AU2017311542A patent/AU2017311542B2/en not_active Ceased
- 2017-08-07 CN CN202311795884.XA patent/CN117736281A/zh active Pending
- 2017-08-07 JP JP2019507171A patent/JP6951417B2/ja active Active
- 2017-08-07 WO PCT/EP2017/069979 patent/WO2018029158A1/en not_active Ceased
- 2017-08-07 AU AU2017311541A patent/AU2017311541B2/en active Active
- 2017-08-07 EP EP22193930.9A patent/EP4177260A1/en active Pending
- 2017-08-07 KR KR1020237030862A patent/KR20230133943A/ko active Pending
- 2017-08-07 KR KR1020197003966A patent/KR102573370B1/ko active Active
- 2017-08-07 LT LTEPPCT/EP2017/069976T patent/LT3497117T/lt unknown
- 2017-08-07 DK DK17752349.5T patent/DK3497117T5/da active
- 2017-08-07 CA CA3031858A patent/CA3031858A1/en active Pending
- 2017-08-07 WO PCT/EP2017/069976 patent/WO2018029157A1/en not_active Ceased
- 2017-08-07 EP EP17752350.3A patent/EP3497118B1/en active Active
- 2017-08-07 CN CN202210871980.7A patent/CN116333065A/zh active Pending
- 2017-08-07 SG SG11201901066UA patent/SG11201901066UA/en unknown
- 2017-08-07 KR KR1020197003790A patent/KR102578256B1/ko active Active
- 2017-08-07 JP JP2019505354A patent/JP7181612B2/ja active Active
- 2017-08-07 EP EP23218805.2A patent/EP4324840A3/en active Pending
- 2017-08-07 EP EP17752349.5A patent/EP3497117B1/en active Active
- 2017-08-07 CN CN201780044905.0A patent/CN109476712B/zh active Active
- 2017-08-07 CN CN201780050413.2A patent/CN109963864B/zh active Active
- 2017-08-07 US US16/324,842 patent/US11014967B2/en active Active
- 2017-08-07 US US16/324,651 patent/US11230576B2/en active Active
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2021
- 2021-03-23 US US17/209,455 patent/US20210206815A1/en not_active Abandoned
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2022
- 2022-07-13 JP JP2022112299A patent/JP2022160444A/ja active Pending
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2024
- 2024-09-03 US US18/822,867 patent/US20250051400A1/en active Pending