LT3497117T - Nauji šarminiai stabilūs imunoglobuliną surišantys baltymai - Google Patents
Nauji šarminiai stabilūs imunoglobuliną surišantys baltymaiInfo
- Publication number
- LT3497117T LT3497117T LTEPPCT/EP2017/069976T LTEP2017069976T LT3497117T LT 3497117 T LT3497117 T LT 3497117T LT EP2017069976 T LTEP2017069976 T LT EP2017069976T LT 3497117 T LT3497117 T LT 3497117T
- Authority
- LT
- Lithuania
- Prior art keywords
- binding proteins
- alkaline stable
- novel alkaline
- stable immunoglobulin
- immunoglobulin
- Prior art date
Links
- 102000028557 immunoglobulin binding proteins Human genes 0.000 title 1
- 108091009323 immunoglobulin binding proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/424—Elution mode
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16183710 | 2016-08-11 | ||
| EP16205707 | 2016-12-21 | ||
| PCT/EP2017/069976 WO2018029157A1 (en) | 2016-08-11 | 2017-08-07 | Novel alkaline stable immunoglobulin-binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3497117T true LT3497117T (lt) | 2024-05-10 |
Family
ID=59631752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/EP2017/069976T LT3497117T (lt) | 2016-08-11 | 2017-08-07 | Nauji šarminiai stabilūs imunoglobuliną surišantys baltymai |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US11230576B2 (enExample) |
| EP (4) | EP3497118B1 (enExample) |
| JP (3) | JP7181612B2 (enExample) |
| KR (3) | KR102573370B1 (enExample) |
| CN (4) | CN109963864B (enExample) |
| AU (2) | AU2017311541B2 (enExample) |
| CA (2) | CA3031858A1 (enExample) |
| DK (1) | DK3497117T5 (enExample) |
| LT (1) | LT3497117T (enExample) |
| SG (1) | SG11201901066UA (enExample) |
| WO (2) | WO2018029157A1 (enExample) |
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| CA2991812C (en) | 2015-07-16 | 2024-02-13 | Navigo Proteins Gmbh | Immunoglobulin-binding proteins and their use in affinity purification |
| JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
| CA3022751A1 (en) | 2016-05-04 | 2017-11-09 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
| CN109963864B (zh) * | 2016-08-11 | 2024-01-02 | 瑞普利金公司 | 用于亲和色谱的碱性稳定性fc结合蛋白 |
| EP3546476A1 (en) * | 2018-03-26 | 2019-10-02 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| EP4491268A3 (en) * | 2017-08-07 | 2025-04-09 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| WO2019091918A1 (en) | 2017-11-07 | 2019-05-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer |
| EP4249097A3 (en) | 2018-02-01 | 2024-01-10 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| JP7591284B2 (ja) * | 2018-11-12 | 2024-11-28 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 免疫グロブリンＦｃドメインに対する結合親和性を持たない新規三重らせんポリペプチド及び同ポリペプチドの使用 |
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| AU2020213921B2 (en) * | 2019-02-01 | 2022-06-16 | Navigo Proteins Gmbh | Immunoglobulin binding proteins for affinity purification |
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| JP7432813B2 (ja) * | 2019-09-10 | 2024-02-19 | 東ソー株式会社 | 免疫グロブリン結合性タンパク質 |
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| WO2021165395A1 (en) * | 2020-02-21 | 2021-08-26 | Navigo Proteins Gmbh | Affinity ligand for the soluble part of fibroblast growth factor receptor 3 (sfgfr3) |
| EP3875472A1 (en) * | 2020-03-06 | 2021-09-08 | Navigo Proteins Gmbh | Novel immunoglobulin binding polypeptides |
| CA3183655A1 (en) * | 2020-06-23 | 2021-12-30 | Mathias KAHL | Binding protein specific for the spike protein of severe acute respiratory syndrome corona virus 2 (sars-cov-2) |
| EP4132943B1 (en) * | 2020-07-15 | 2024-05-29 | Navigo Proteins Gmbh | Immunoglobulin binding proteins for affinity purification |
| JP2023547340A (ja) * | 2020-11-09 | 2023-11-10 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規ｉｉ型コラーゲン結合タンパク質 |
| EP4001301A1 (en) * | 2020-11-13 | 2022-05-25 | Navigo Proteins Gmbh | Binding protein for complement factor h (cfh) |
| EP4380955A1 (en) * | 2021-08-06 | 2024-06-12 | Roche Diagnostics GmbH | Chimeric igg-fc-binding ligand polypeptide and uses thereof for igg affinity purification |
| GB202113626D0 (en) | 2021-09-24 | 2021-11-10 | Cytiva Bioprocess R & D Ab | FC binding polypeptides |
| CN116675729A (zh) * | 2021-12-21 | 2023-09-01 | 百林科(兰州)新材料有限公司 | 耐碱蛋白A变体去除样品中IgG抗体的应用 |
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| CA2991812C (en) | 2015-07-16 | 2024-02-13 | Navigo Proteins Gmbh | Immunoglobulin-binding proteins and their use in affinity purification |
| JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
| CA2991814A1 (en) | 2015-07-20 | 2017-01-26 | Navigo Proteins Gmbh | Her2 binding proteins based on di-ubiquitin muteins |
| CA3022751A1 (en) | 2016-05-04 | 2017-11-09 | Navigo Proteins Gmbh | Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker |
| CN109963864B (zh) | 2016-08-11 | 2024-01-02 | 瑞普利金公司 | 用于亲和色谱的碱性稳定性fc结合蛋白 |
| EP4491268A3 (en) | 2017-08-07 | 2025-04-09 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| WO2019091918A1 (en) | 2017-11-07 | 2019-05-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer |
| EP4249097A3 (en) | 2018-02-01 | 2024-01-10 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
-
2017
- 2017-08-07 CN CN201780050413.2A patent/CN109963864B/zh active Active
- 2017-08-07 JP JP2019505354A patent/JP7181612B2/ja active Active
- 2017-08-07 WO PCT/EP2017/069976 patent/WO2018029157A1/en not_active Ceased
- 2017-08-07 CN CN202210871980.7A patent/CN116333065A/zh active Pending
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