LT3497117T - Nauji šarminiai stabilūs imunoglobuliną surišantys baltymai - Google Patents
Nauji šarminiai stabilūs imunoglobuliną surišantys baltymaiInfo
- Publication number
- LT3497117T LT3497117T LTEPPCT/EP2017/069976T LTEP2017069976T LT3497117T LT 3497117 T LT3497117 T LT 3497117T LT EP2017069976 T LTEP2017069976 T LT EP2017069976T LT 3497117 T LT3497117 T LT 3497117T
- Authority
- LT
- Lithuania
- Prior art keywords
- binding proteins
- alkaline stable
- novel alkaline
- stable immunoglobulin
- immunoglobulin
- Prior art date
Links
- 102000028557 immunoglobulin binding proteins Human genes 0.000 title 1
- 108091009323 immunoglobulin binding proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/424—Elution mode
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
- B01J20/26—Synthetic macromolecular compounds
- B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16183710 | 2016-08-11 | ||
| EP16205707 | 2016-12-21 | ||
| PCT/EP2017/069976 WO2018029157A1 (en) | 2016-08-11 | 2017-08-07 | Novel alkaline stable immunoglobulin-binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3497117T true LT3497117T (lt) | 2024-05-10 |
Family
ID=59631752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/EP2017/069976T LT3497117T (lt) | 2016-08-11 | 2017-08-07 | Nauji šarminiai stabilūs imunoglobuliną surišantys baltymai |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11014967B2 (lt) |
| EP (4) | EP4177260A1 (lt) |
| JP (3) | JP7181612B2 (lt) |
| KR (3) | KR102573370B1 (lt) |
| CN (4) | CN116333065A (lt) |
| AU (2) | AU2017311541B2 (lt) |
| CA (2) | CA3030208A1 (lt) |
| DK (1) | DK3497117T5 (lt) |
| LT (1) | LT3497117T (lt) |
| SG (1) | SG11201901066UA (lt) |
| WO (2) | WO2018029158A1 (lt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3253785T3 (da) | 2015-02-06 | 2019-07-08 | Navigo Proteins Gmbh | Hidtil ukendte egfr-bindingsproteiner |
| BR112018000477A2 (pt) | 2015-07-16 | 2018-09-18 | Navigo Proteins Gmbh | proteína de ligação de imunoglobulina não natural, composição, uso da proteína de ligação de ig não natural, método de purificação de afinidade de imunoglobulinas, método de geração de uma proteína de ligação de imunoglobulina não natural, molécula de ácido nucleico, vetor, célula hospedeira ou um hospedeiro não humano, e método para a produção de uma proteína de ligação de imunoglobulina não natural |
| WO2017013136A1 (en) | 2015-07-20 | 2017-01-26 | Scil Proteins Gmbh | Novel binding proteins based on di-ubiquitin muteins and methods for generation |
| CN109310780A (zh) | 2016-05-04 | 2019-02-05 | 纳维格蛋白质有限公司 | 包含肽接头的用于化学部分位点-特异性偶联的靶向化合物 |
| EP4177260A1 (en) | 2016-08-11 | 2023-05-10 | Repligen Corporation | Alkaline stable fc-binding proteins for affinity chromatography |
| EP3521304B9 (en) * | 2018-02-01 | 2023-10-04 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| WO2019030156A1 (en) * | 2017-08-07 | 2019-02-14 | Repligen Corporation | FC BINDING PROTEINS WITH CYSTEINE IN THE C-TERMINAL HELICAL REGION |
| EP3546476A1 (en) * | 2018-03-26 | 2019-10-02 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| US11414466B2 (en) | 2017-11-07 | 2022-08-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer |
| EP3650465A1 (en) | 2018-11-12 | 2020-05-13 | Navigo Proteins Gmbh | Novel populations of polypeptides having a triple-helical structure |
| LT3880692T (lt) * | 2018-11-12 | 2024-02-26 | Navigo Proteins Gmbh | Nauji trigubos spiralės polipeptidai, stokojantys surišimo giminingumo imunoglobulino fc domenui, ir jų panaudojimas |
| SG11202106848UA (en) * | 2019-02-01 | 2021-08-30 | Navigo Proteins Gmbh | Immunoglobulin binding proteins for affinity purification |
| GB201904125D0 (en) | 2019-03-26 | 2019-05-08 | Ge Healthcare Bio Sciences Ab | Method for sanitization of a chromatography column |
| JP7432813B2 (ja) * | 2019-09-10 | 2024-02-19 | 東ソー株式会社 | 免疫グロブリン結合性タンパク質 |
| EP4077357B1 (en) * | 2019-12-17 | 2023-09-06 | Navigo Proteins Gmbh | Binding proteins for the enzyme acid alpha glucosidase (gaa) and uses thereof |
| EP4107178B1 (en) * | 2020-02-21 | 2024-01-10 | Navigo Proteins Gmbh | Affinity ligand for the soluble part of fibroblast growth factor receptor 3 (sfgfr3) |
| EP3875472A1 (en) * | 2020-03-06 | 2021-09-08 | Navigo Proteins Gmbh | Novel immunoglobulin binding polypeptides |
| EP4132943B1 (en) * | 2020-07-15 | 2024-05-29 | Navigo Proteins Gmbh | Immunoglobulin binding proteins for affinity purification |
| EP4001301A1 (en) * | 2020-11-13 | 2022-05-25 | Navigo Proteins Gmbh | Binding protein for complement factor h (cfh) |
| GB202113626D0 (en) | 2021-09-24 | 2021-11-10 | Cytiva Bioprocess R & D Ab | FC binding polypeptides |
| CN116925197A (zh) * | 2021-12-21 | 2023-10-24 | 百林科(兰州)新材料有限公司 | 耐碱蛋白A变体在纯化IgG抗体中的应用 |
| CN113999294B (zh) * | 2021-12-30 | 2022-03-29 | 苏州纳微科技股份有限公司 | 免疫球蛋白结合蛋白及其应用 |
| CN114409748A (zh) * | 2022-01-28 | 2022-04-29 | 博格隆(浙江)生物技术有限公司 | 蛋白a的b结构域和z结构域突变体及其应用 |
| GB202203478D0 (en) | 2022-03-14 | 2022-04-27 | Cytiva Bioprocess R & D Ab | Vh3 binding polypeptides |
| WO2024126837A1 (en) * | 2022-12-16 | 2024-06-20 | Navigo Proteins Gmbh | New ligands for affinity chromatography |
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| DK3253785T3 (da) | 2015-02-06 | 2019-07-08 | Navigo Proteins Gmbh | Hidtil ukendte egfr-bindingsproteiner |
| DK3253795T3 (da) | 2015-02-06 | 2019-07-29 | Navigo Proteins Gmbh | Hidtil ukendte bindende proteiner, der omfatter et ubiquitin-mutein, og antistoffer eller antistoffragmenter |
| BR112018000477A2 (pt) | 2015-07-16 | 2018-09-18 | Navigo Proteins Gmbh | proteína de ligação de imunoglobulina não natural, composição, uso da proteína de ligação de ig não natural, método de purificação de afinidade de imunoglobulinas, método de geração de uma proteína de ligação de imunoglobulina não natural, molécula de ácido nucleico, vetor, célula hospedeira ou um hospedeiro não humano, e método para a produção de uma proteína de ligação de imunoglobulina não natural |
| WO2017013136A1 (en) | 2015-07-20 | 2017-01-26 | Scil Proteins Gmbh | Novel binding proteins based on di-ubiquitin muteins and methods for generation |
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| CN109310780A (zh) | 2016-05-04 | 2019-02-05 | 纳维格蛋白质有限公司 | 包含肽接头的用于化学部分位点-特异性偶联的靶向化合物 |
| EP4177260A1 (en) | 2016-08-11 | 2023-05-10 | Repligen Corporation | Alkaline stable fc-binding proteins for affinity chromatography |
| WO2019030156A1 (en) | 2017-08-07 | 2019-02-14 | Repligen Corporation | FC BINDING PROTEINS WITH CYSTEINE IN THE C-TERMINAL HELICAL REGION |
| EP3521304B9 (en) | 2018-02-01 | 2023-10-04 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| US11414466B2 (en) | 2017-11-07 | 2022-08-16 | Navigo Proteins Gmbh | Fusion proteins with specificity for ED-B and long serum half-life for diagnosis or treatment of cancer |
-
2017
- 2017-08-07 EP EP22193930.9A patent/EP4177260A1/en active Pending
- 2017-08-07 US US16/324,842 patent/US11014967B2/en active Active
- 2017-08-07 CA CA3030208A patent/CA3030208A1/en active Pending
- 2017-08-07 JP JP2019505354A patent/JP7181612B2/ja active Active
- 2017-08-07 KR KR1020197003966A patent/KR102573370B1/ko active IP Right Grant
- 2017-08-07 CN CN202210871980.7A patent/CN116333065A/zh active Pending
- 2017-08-07 KR KR1020237030862A patent/KR20230133943A/ko not_active Application Discontinuation
- 2017-08-07 SG SG11201901066UA patent/SG11201901066UA/en unknown
- 2017-08-07 AU AU2017311541A patent/AU2017311541B2/en active Active
- 2017-08-07 DK DK17752349.5T patent/DK3497117T5/da active
- 2017-08-07 EP EP17752349.5A patent/EP3497117B1/en active Active
- 2017-08-07 LT LTEPPCT/EP2017/069976T patent/LT3497117T/lt unknown
- 2017-08-07 EP EP23218805.2A patent/EP4324840A3/en active Pending
- 2017-08-07 CN CN201780044905.0A patent/CN109476712B/zh active Active
- 2017-08-07 CN CN201780050413.2A patent/CN109963864B/zh active Active
- 2017-08-07 WO PCT/EP2017/069979 patent/WO2018029158A1/en unknown
- 2017-08-07 US US16/324,651 patent/US11230576B2/en active Active
- 2017-08-07 KR KR1020197003790A patent/KR102578256B1/ko active IP Right Grant
- 2017-08-07 AU AU2017311542A patent/AU2017311542B2/en active Active
- 2017-08-07 WO PCT/EP2017/069976 patent/WO2018029157A1/en unknown
- 2017-08-07 JP JP2019507171A patent/JP6951417B2/ja active Active
- 2017-08-07 EP EP17752350.3A patent/EP3497118B1/en active Active
- 2017-08-07 CA CA3031858A patent/CA3031858A1/en active Pending
- 2017-08-07 CN CN202311795884.XA patent/CN117736281A/zh active Pending
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2021
- 2021-03-23 US US17/209,455 patent/US20210206815A1/en active Pending
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2022
- 2022-07-13 JP JP2022112299A patent/JP2022160444A/ja active Pending
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