HK1250034A1 - 新型抗-pcsk9抗體 - Google Patents

新型抗-pcsk9抗體

Info

Publication number
HK1250034A1
HK1250034A1 HK18109418.5A HK18109418A HK1250034A1 HK 1250034 A1 HK1250034 A1 HK 1250034A1 HK 18109418 A HK18109418 A HK 18109418A HK 1250034 A1 HK1250034 A1 HK 1250034A1
Authority
HK
Hong Kong
Prior art keywords
novel anti
pcsk9 antibodies
pcsk9
antibodies
novel
Prior art date
Application number
HK18109418.5A
Other languages
English (en)
Inventor
劉潔穎
李競
G‧戈洛洛博夫
Original Assignee
上海藥明生物技術有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 上海藥明生物技術有限公司 filed Critical 上海藥明生物技術有限公司
Publication of HK1250034A1 publication Critical patent/HK1250034A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK18109418.5A 2016-09-20 2018-07-20 新型抗-pcsk9抗體 HK1250034A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610835878 2016-09-20

Publications (1)

Publication Number Publication Date
HK1250034A1 true HK1250034A1 (zh) 2018-11-23

Family

ID=61683325

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18109418.5A HK1250034A1 (zh) 2016-09-20 2018-07-20 新型抗-pcsk9抗體

Country Status (3)

Country Link
CN (1) CN107840892A (zh)
HK (1) HK1250034A1 (zh)
TW (1) TW201825524A (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111171152B (zh) * 2020-01-15 2023-04-18 吉林医药学院 Pcsk9抗体及其制备方法和应用
WO2021159235A1 (zh) * 2020-02-10 2021-08-19 深圳华大生命科学研究院 Pcsk9的单域抗体及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR070316A1 (es) * 2008-02-07 2010-03-31 Merck & Co Inc Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9)
RU2668170C2 (ru) * 2011-04-25 2018-09-26 Дайити Санкио Компани, Лимитед Анти-в7-н3-антитело
SI3342785T1 (sl) * 2012-10-11 2020-02-28 Daiichi Sankyo Company, Limited Povezovalci za konjugate protitelesa in zdravila
CN104861071B (zh) * 2015-04-27 2019-04-12 南京师范大学 针对pcsk9的全人源单克隆抗体的可变区基因及其应用
CN105801701B (zh) * 2016-03-31 2019-03-29 河北仁博科技有限公司 一种pcsk9抗体的重链和轻链可变区及其应用

Also Published As

Publication number Publication date
TW201825524A (zh) 2018-07-16
CN107840892A (zh) 2018-03-27

Similar Documents

Publication Publication Date Title
ZA201900373B (en) Anti-tim-3 antibodies
SG10201601719RA (en) Anti-LAG-3 Antibodies
GB201621439D0 (en) IL-11Ra Antibodies
GB201601073D0 (en) Antibodies
GB201411320D0 (en) Antibody construct
SG11201706126WA (en) Anti-transthyretin antibodies
GB201610044D0 (en) Antibodies
GB201603291D0 (en) Antibodies
ZA201604640B (en) Novel anti-netrin-1 antibody
IL264262A (en) Antibodies against interleukin 22 receptors
SI3628731T1 (sl) Novo protitelo proti presepsinu
GB201616699D0 (en) Antibodies
EP3515949A4 (en) NEW ANTI-PCSK9 ANTIBODIES
HK1250034A1 (zh) 新型抗-pcsk9抗體
ZA201808317B (en) Anti-tnfrsf25 antibodies
IL260083A (en) Antibody against myl9
EP3515950A4 (en) NEW ANTI-PCSK9 ANTIBODIES
HK1249538A1 (zh) 新型抗-pcsk9抗體
GB201622197D0 (en) Antibodies
GB201620414D0 (en) Antibodies
GB201615224D0 (en) Antibodies
GB201613158D0 (en) Antibodies
GB201612437D0 (en) Anti-lag-3 antibodies
GB201514425D0 (en) Antibodies
GB201502591D0 (en) Antibodies