LT3880692T - Nauji trigubos spiralės polipeptidai, stokojantys surišimo giminingumo imunoglobulino fc domenui, ir jų panaudojimas - Google Patents

Nauji trigubos spiralės polipeptidai, stokojantys surišimo giminingumo imunoglobulino fc domenui, ir jų panaudojimas

Info

Publication number
LT3880692T
LT3880692T LTEPPCT/EP2019/081078T LTEP2019081078T LT3880692T LT 3880692 T LT3880692 T LT 3880692T LT EP2019081078 T LTEP2019081078 T LT EP2019081078T LT 3880692 T LT3880692 T LT 3880692T
Authority
LT
Lithuania
Prior art keywords
immunoglobulin
domain
binding affinity
polypeptides lacking
novel triple
Prior art date
Application number
LTEPPCT/EP2019/081078T
Other languages
English (en)
Inventor
Erik Fiedler
Ulrich Haupts
Madlen ZWARG
Original Assignee
Navigo Proteins Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Navigo Proteins Gmbh filed Critical Navigo Proteins Gmbh
Publication of LT3880692T publication Critical patent/LT3880692T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/705Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
LTEPPCT/EP2019/081078T 2018-11-12 2019-11-12 Nauji trigubos spiralės polipeptidai, stokojantys surišimo giminingumo imunoglobulino fc domenui, ir jų panaudojimas LT3880692T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18205679 2018-11-12
EP19167107 2019-04-03
PCT/EP2019/081078 WO2020099442A1 (en) 2018-11-12 2019-11-12 Novel triple-helical polypeptides lacking binding affinity for the fc domain of immunoglobulin and uses thereof

Publications (1)

Publication Number Publication Date
LT3880692T true LT3880692T (lt) 2024-02-26

Family

ID=68536874

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2019/081078T LT3880692T (lt) 2018-11-12 2019-11-12 Nauji trigubos spiralės polipeptidai, stokojantys surišimo giminingumo imunoglobulino fc domenui, ir jų panaudojimas

Country Status (14)

Country Link
US (1) US20220073564A1 (lt)
EP (2) EP3880692B1 (lt)
JP (1) JP2022504487A (lt)
KR (1) KR20210092203A (lt)
CN (1) CN112969708B (lt)
AU (1) AU2019380620B2 (lt)
BR (1) BR112021007530A2 (lt)
CA (1) CA3116514A1 (lt)
DK (1) DK3880692T3 (lt)
IL (1) IL281849A (lt)
LT (1) LT3880692T (lt)
SG (1) SG11202103139PA (lt)
WO (1) WO2020099442A1 (lt)
ZA (1) ZA202102579B (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230272050A1 (en) * 2020-06-23 2023-08-31 Navigo Proteins Gmbh Binding protein specific for the spike protein of severe acute respiratory syndrome corona virus 2 (sars-cov-2)
EP4001301A1 (en) * 2020-11-13 2022-05-25 Navigo Proteins Gmbh Binding protein for complement factor h (cfh)
EP4370529A1 (en) * 2021-07-13 2024-05-22 Navigo Proteins Gmbh Affinity ligands for the purification and detection of ubiquitin muteins
WO2023057617A1 (en) * 2021-10-08 2023-04-13 Navigo Proteins Gmbh Specific baculovirus major envelope glycoprotein gp64 binding proteins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107686513A (zh) * 2010-03-08 2018-02-13 通用电气医疗集团生物工艺研发股份公司 免疫球蛋白G Fc区结合多肽
EP3276002B1 (en) * 2015-03-26 2020-04-29 JSR Corporation Immunoglobulin-binding protein and affinity carrier using same
KR20160126340A (ko) * 2015-04-23 2016-11-02 삼성전자주식회사 3중-나선 다발 단백질 및 이의 용도
KR102064396B1 (ko) * 2015-07-16 2020-01-09 나피고 프로타인스 게엠베하 신규한 면역글로불린-결합 단백질 및 친화도 정제에서의 이의 용도
JPWO2017014261A1 (ja) * 2015-07-22 2018-04-26 株式会社カネカ 抗体様タンパク質の精製方法
EP3327029A4 (en) * 2015-07-22 2018-10-31 Kaneka Corporation ANTIBODY-BINDING PROTEIN HAVING REDUCED ANTIBODY-BINDING CAPACITY IN ACIDIC pH REGIONS
EP3650465A1 (en) * 2018-11-12 2020-05-13 Navigo Proteins Gmbh Novel populations of polypeptides having a triple-helical structure

Also Published As

Publication number Publication date
EP4349853A2 (en) 2024-04-10
DK3880692T3 (da) 2024-02-12
EP3880692B1 (en) 2024-01-03
US20220073564A1 (en) 2022-03-10
CA3116514A1 (en) 2020-05-22
BR112021007530A2 (pt) 2021-08-31
WO2020099442A1 (en) 2020-05-22
CN112969708B (zh) 2024-07-05
AU2019380620B2 (en) 2022-05-26
JP2022504487A (ja) 2022-01-13
SG11202103139PA (en) 2021-04-29
WO2020099442A9 (en) 2020-07-09
ZA202102579B (en) 2023-01-25
EP4349853A3 (en) 2024-07-03
EP3880692A1 (en) 2021-09-22
AU2019380620A1 (en) 2021-04-29
IL281849A (en) 2021-05-31
CN112969708A (zh) 2021-06-15
KR20210092203A (ko) 2021-07-23

Similar Documents

Publication Publication Date Title
ZA202102579B (en) Novel triple-helical polypeptides lacking binding affinity for the fc domain of immunoglobulin and uses thereof
GB2596461B (en) Binding proteins specific for RAS neoantigens and uses thereof
IL278091A (en) Heterodimeric 1-PD-targeted OH-FC proteins containing OH-IL-15/IL-15Rα FC proteins and 1-PD antigen binding regions and uses thereof
SG11202102851XA (en) SIRPa BINDING PROTEINS AND METHODS OF USE THEREOF
IL278924A (en) Antibodies specific to GUCY2C and their uses
IL279510A (en) Progranulin-FC polypeptide fusion proteins and their uses
IL277287A (en) Antibodies against MICA and/or MICB and uses thereof
EP3849608C0 (en) NEW LILRB4 ANTIBODIES AND USES THEREOF
EP3797164A4 (en) CHEMERA ANTIGEN RECEPTORS WITH MODIFIED BINDING DOMAINS AND USES THEREOF
SG11202101675UA (en) Anti-bcma single domain antibodies and application thereof
EP4249097A3 (en) Fc binding proteins with cysteine in the c-terminal helical region
PH12014501818A1 (en) Pseudomonas aeruginosa pcrv binding single variable domain antibodies
IL280995A (en) Antibodies that bind CITRULLINATED HISTONE 2A and/or 4
EP3708575A4 (en) THIOREDOXIN-1 EPITOPE AND SPECIFICALLY BONDING MONOCLONAL ANTIBODIES
EP3995508A4 (en) NOVEL MODIFIED IMMUNOGLOBULIN FC FUSION PROTEIN AND USE THEREOF
SG11202013217PA (en) Multifunctional protein molecules comprising decorin and use thereof
SG11202103095RA (en) Anti-human vsig4 antibodies and uses thereof
EP4041772A4 (en) 4-1BB-BINDING ANTIBODIES AND USES THEREOF
IL286216A (en) tsg-6 antibodies and uses thereof
IL275593B (en) A preparation containing probiotics and peptides with binding affinity to ige and its uses
EP3802831A4 (en) POLYPEPTIDE COMPRISING AN IL-1R1 BINDING DOMAIN AND A TRANSPORT FRACTION
SG11202007443XA (en) Cd38 protein antibody and application thereof
MX2020002934A (es) Variantes de anticuerpos.
EP3655026A4 (en) ANTIGBINDING REGIONS AGAINST FIBRONECTIN TYPE III DOMAINS AND METHOD OF USING THEREOF
EP4017529A4 (en) FIELDS FC VARIANTS AND THEIR USES