JP2019529514A5 - - Google Patents

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JP2019529514A5
JP2019529514A5 JP2019518267A JP2019518267A JP2019529514A5 JP 2019529514 A5 JP2019529514 A5 JP 2019529514A5 JP 2019518267 A JP2019518267 A JP 2019518267A JP 2019518267 A JP2019518267 A JP 2019518267A JP 2019529514 A5 JP2019529514 A5 JP 2019529514A5
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Japan
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pharmaceutical composition
composition according
salt
compound
proteinosis
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JP2019518267A
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JP2019529514A (ja
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Priority claimed from PCT/US2016/055561 external-priority patent/WO2017062500A2/en
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Claims (8)

  1. 以下:
    Figure 2019529514
    からなる群より選択される化合物、またはその塩、鏡像異性体、ラセミ体、それらの混合物、もしくはそれらの組み合わせ。
  2. 以下:
    Figure 2019529514
    の化合物、またはその塩。
  3. 請求項1または請求項2に記載の化合物または薬学的に許容されるその塩を含む医薬組成物。
  4. 神経変性疾患の治療のための、請求項3に記載の医薬組成物。
  5. 前記神経変性疾患がタンパク質症である、請求項4に記載の医薬組成物。
  6. 前記タンパク質症がタウオパチーである、請求項5に記載の医薬組成物。
  7. 前記神経変性疾患がアルツハイマー病である、請求項4に記載の医薬組成物。
  8. 細胞またはタンパク質凝集体においてオートファジーフラックスを亢進するための、請求項3に記載の医薬組成物。
JP2019518267A 2015-10-05 2017-10-03 オートファジーフラックス及びホスホリパーゼd及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法 Pending JP2019529514A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562237342P 2015-10-05 2015-10-05
PCT/US2016/055561 WO2017062500A2 (en) 2015-10-05 2016-10-05 Activators of autophagic flux and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies
USPCT/US2016/055561 2016-10-05
US15/480,220 2017-04-05
US15/480,220 US10487091B2 (en) 2015-10-05 2017-04-05 Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies
PCT/US2017/054969 WO2018067589A1 (en) 2015-10-05 2017-10-03 Activators of autophagic flux and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies

Publications (2)

Publication Number Publication Date
JP2019529514A JP2019529514A (ja) 2019-10-17
JP2019529514A5 true JP2019529514A5 (ja) 2020-11-12

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JP2018536715A Active JP6740354B2 (ja) 2015-10-05 2016-10-05 オートファジーの流れ及びホスホリパーゼd及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
JP2019518267A Pending JP2019529514A (ja) 2015-10-05 2017-10-03 オートファジーフラックス及びホスホリパーゼd及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
JP2020102147A Withdrawn JP2020147597A (ja) 2015-10-05 2020-06-12 オートファジーの流れ及びホスホリパーゼd及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法

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JP2020102147A Withdrawn JP2020147597A (ja) 2015-10-05 2020-06-12 オートファジーの流れ及びホスホリパーゼd及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法

Country Status (12)

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US (6) US20190112317A1 (ja)
EP (2) EP3359526A4 (ja)
JP (3) JP6740354B2 (ja)
KR (2) KR20180086187A (ja)
CN (2) CN108473435A (ja)
AU (2) AU2016333987A1 (ja)
BR (2) BR112018006873A2 (ja)
CA (2) CA3000988A1 (ja)
IL (2) IL258498A (ja)
MX (2) MX2018004109A (ja)
WO (2) WO2017062500A2 (ja)
ZA (2) ZA201802294B (ja)

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WO2020109039A1 (en) 2018-11-28 2020-06-04 Basf Se Pesticidal compounds
EA202191507A1 (ru) * 2018-11-30 2021-08-20 Селулэрити Инк. Ароматические соединения для применения для активации кроветворных стволовых клеток и клеток-предшественников
KR20230051238A (ko) 2020-09-17 2023-04-17 가부시끼가이샤 레조낙 오토파지 활성화제
JPWO2022059775A1 (ja) 2020-09-17 2022-03-24
KR20230051237A (ko) 2020-09-17 2023-04-17 가부시끼가이샤 레조낙 오토파지 활성화제
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WO2023081860A1 (en) * 2021-11-04 2023-05-11 Skyhawk Therapeutics, Inc. Triazine amino derivatives for treating sca3

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