JP2017075173A5 - - Google Patents
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- Publication number
- JP2017075173A5 JP2017075173A5 JP2016249232A JP2016249232A JP2017075173A5 JP 2017075173 A5 JP2017075173 A5 JP 2017075173A5 JP 2016249232 A JP2016249232 A JP 2016249232A JP 2016249232 A JP2016249232 A JP 2016249232A JP 2017075173 A5 JP2017075173 A5 JP 2017075173A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- compound
- amyloidosis
- condition associated
- pathological condition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 206010002023 Amyloidosis Diseases 0.000 claims 5
- 206010002022 Amyloidosis Diseases 0.000 claims 5
- 230000001575 pathological Effects 0.000 claims 5
- 206010001897 Alzheimer's disease Diseases 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000005755 formation reaction Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 0 *C(C1*)[C@](*)C(*)C(*)[C@]1O Chemical compound *C(C1*)[C@](*)C(*)C(*)[C@]1O 0.000 description 14
- PXKXMLOHKWCCGD-XNIMQTFVSA-N O[C@@H](C(C(C(OCc1ccccc1)=C1OCc2ccccc2)OCc2ccccc2)OCc2ccccc2)C1O Chemical compound O[C@@H](C(C(C(OCc1ccccc1)=C1OCc2ccccc2)OCc2ccccc2)OCc2ccccc2)C1O PXKXMLOHKWCCGD-XNIMQTFVSA-N 0.000 description 1
Claims (11)
- アミロイドーシスに関連する病的症状がアルツハイマー病である、請求項4から6のいずれか一項に記載の医薬組成物。
- アミロイドーシスに関連する病的症状がアルツハイマー病である、請求項8または9に記載の使用。
- 治療が斑の形成を阻害する、請求項8から10のいずれか一項に記載の使用。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3857108P | 2008-03-21 | 2008-03-21 | |
US61/038,571 | 2008-03-21 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014046341A Division JP6140090B2 (ja) | 2008-03-21 | 2014-03-10 | アルツハイマー病及び関連疾患の検出及び治療のための化合物及び組成物 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2017075173A JP2017075173A (ja) | 2017-04-20 |
JP2017075173A5 true JP2017075173A5 (ja) | 2017-11-24 |
JP6370361B2 JP6370361B2 (ja) | 2018-08-08 |
Family
ID=41091569
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011501009A Active JP5501339B2 (ja) | 2008-03-21 | 2009-03-23 | アルツハイマー病及び関連疾患の検出及び治療のための化合物及び組成物 |
JP2014046341A Active JP6140090B2 (ja) | 2008-03-21 | 2014-03-10 | アルツハイマー病及び関連疾患の検出及び治療のための化合物及び組成物 |
JP2016249232A Active JP6370361B2 (ja) | 2008-03-21 | 2016-12-22 | アルツハイマー病及び関連疾患の検出及び治療のための化合物及び組成物 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011501009A Active JP5501339B2 (ja) | 2008-03-21 | 2009-03-23 | アルツハイマー病及び関連疾患の検出及び治療のための化合物及び組成物 |
JP2014046341A Active JP6140090B2 (ja) | 2008-03-21 | 2014-03-10 | アルツハイマー病及び関連疾患の検出及び治療のための化合物及び組成物 |
Country Status (9)
Country | Link |
---|---|
US (5) | US8450466B2 (ja) |
EP (2) | EP3231804B1 (ja) |
JP (3) | JP5501339B2 (ja) |
CN (2) | CN102046638B (ja) |
AU (1) | AU2009225407B2 (ja) |
CA (2) | CA2718035C (ja) |
HK (2) | HK1157323A1 (ja) |
MX (1) | MX2010010314A (ja) |
WO (1) | WO2009117728A2 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8257680B1 (en) | 2004-02-24 | 2012-09-04 | The General Hospital Corporation | Catalytic radiofluorination |
US9017724B2 (en) | 2004-02-24 | 2015-04-28 | The General Hospital Corporation | Catalytic radiofluorination |
US8450466B2 (en) * | 2008-03-21 | 2013-05-28 | The General Hosptial Corporation | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders |
US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
NZ607257A (en) * | 2010-08-16 | 2015-02-27 | Cognoptix Inc | System and method for detecting amyloid proteins |
CA2824858A1 (en) * | 2011-01-18 | 2012-07-26 | General Atomics | Hydrolase enzyme substrates and uses thereof |
US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
ES2749096T3 (es) | 2012-10-25 | 2020-03-19 | Massachusetts Gen Hospital | Terapias de combinación para el tratamiento de la enfermedad de Alzheimery transtornos relacionados |
US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
CN110305095A (zh) | 2013-10-22 | 2019-10-08 | 综合医院公司 | 色甘酸衍生物以及成像和治疗的相关方法 |
ES2946754T3 (es) | 2014-03-19 | 2023-07-25 | Amydis Diagnostics Inc | Agentes para detección de amiloides y métodos para utilizar los mismos |
US20190240194A1 (en) | 2016-08-31 | 2019-08-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
US10675365B2 (en) | 2016-09-29 | 2020-06-09 | Korea Atomic Energy Research Institute | Curcumin derivative, method for producing same, and photo-acoustic imaging agent comprising same for detecting beta-amyloid plaque |
JP7202376B2 (ja) | 2017-07-20 | 2023-01-11 | エーゼットセラピーズ, インコーポレイテッド | クロモリンナトリウムおよびイブプロフェンの粉末製剤 |
CA3105392A1 (en) | 2018-07-02 | 2020-01-09 | The General Hospital Corporation | Powdered formulations of cromolyn sodium and .alpha.-lactose |
BR112021003156A2 (pt) | 2018-08-23 | 2021-05-11 | Seagen, Inc. | composição, anticorpo que se liga ao tigit humano, formulação farmacêutica, polinucleotídeo isolado, vetor, célula hospedeira, métodos para a produção de um anticorpo que se liga ao tigit humano e de anticorpos afucosilados que se ligam a tigit e para o tratamento de um câncer, e, kit. |
WO2023150739A2 (en) * | 2022-02-07 | 2023-08-10 | Moskovitz Martin J | Cryo-surgical device and materials and method of use thereof |
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-
2009
- 2009-03-23 US US12/933,139 patent/US8450466B2/en active Active
- 2009-03-23 CN CN200980119032.0A patent/CN102046638B/zh active Active
- 2009-03-23 WO PCT/US2009/037928 patent/WO2009117728A2/en active Application Filing
- 2009-03-23 CA CA2718035A patent/CA2718035C/en active Active
- 2009-03-23 AU AU2009225407A patent/AU2009225407B2/en active Active
- 2009-03-23 JP JP2011501009A patent/JP5501339B2/ja active Active
- 2009-03-23 CA CA2978149A patent/CA2978149C/en active Active
- 2009-03-23 EP EP17152886.2A patent/EP3231804B1/en active Active
- 2009-03-23 CN CN201510221345.4A patent/CN104974024B/zh active Active
- 2009-03-23 MX MX2010010314A patent/MX2010010314A/es active IP Right Grant
- 2009-03-23 EP EP09723502.2A patent/EP2268647B1/en active Active
-
2011
- 2011-10-24 HK HK11111431.1A patent/HK1157323A1/xx unknown
-
2013
- 2013-05-28 US US13/903,362 patent/US9005578B2/en active Active
-
2014
- 2014-03-10 JP JP2014046341A patent/JP6140090B2/ja active Active
- 2014-12-15 US US14/569,855 patent/US20150098903A1/en not_active Abandoned
-
2016
- 2016-04-11 HK HK16104068.1A patent/HK1217100A1/zh unknown
- 2016-12-22 JP JP2016249232A patent/JP6370361B2/ja active Active
-
2019
- 2019-08-29 US US16/555,290 patent/US10857247B2/en active Active
-
2020
- 2020-12-08 US US17/115,344 patent/US20210338849A1/en not_active Abandoned
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