JP2019528769A5 - - Google Patents
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- JP2019528769A5 JP2019528769A5 JP2019518049A JP2019518049A JP2019528769A5 JP 2019528769 A5 JP2019528769 A5 JP 2019528769A5 JP 2019518049 A JP2019518049 A JP 2019518049A JP 2019518049 A JP2019518049 A JP 2019518049A JP 2019528769 A5 JP2019528769 A5 JP 2019528769A5
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- Prior art keywords
- nucleic acid
- acid molecule
- human
- cell
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021083808A JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2022112159A JP2022160443A (ja) | 2016-10-04 | 2022-07-13 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2024013162A JP2024059633A (ja) | 2016-10-04 | 2024-01-31 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662403880P | 2016-10-04 | 2016-10-04 | |
| US62/403,880 | 2016-10-04 | ||
| US201762501475P | 2017-05-04 | 2017-05-04 | |
| US62/501,475 | 2017-05-04 | ||
| US201762556199P | 2017-09-08 | 2017-09-08 | |
| US62/556,199 | 2017-09-08 | ||
| PCT/US2017/055133 WO2018067697A1 (en) | 2016-10-04 | 2017-10-04 | Co-stimulatory domains for use in genetically-modified cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021083808A Division JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2019528769A JP2019528769A (ja) | 2019-10-17 |
| JP2019528769A5 true JP2019528769A5 (enExample) | 2020-11-12 |
| JP6887492B2 JP6887492B2 (ja) | 2021-06-16 |
| JP6887492B6 JP6887492B6 (ja) | 2021-07-14 |
Family
ID=60382586
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019518049A Active JP6887492B6 (ja) | 2016-10-04 | 2017-10-04 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2021083808A Active JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2022112159A Pending JP2022160443A (ja) | 2016-10-04 | 2022-07-13 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2024013162A Pending JP2024059633A (ja) | 2016-10-04 | 2024-01-31 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021083808A Active JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2022112159A Pending JP2022160443A (ja) | 2016-10-04 | 2022-07-13 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2024013162A Pending JP2024059633A (ja) | 2016-10-04 | 2024-01-31 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US11286291B2 (enExample) |
| EP (3) | EP3523326B1 (enExample) |
| JP (4) | JP6887492B6 (enExample) |
| AU (4) | AU2017338846B2 (enExample) |
| CA (1) | CA3039014A1 (enExample) |
| DK (2) | DK3757120T3 (enExample) |
| ES (2) | ES2811500T3 (enExample) |
| WO (1) | WO2018067697A1 (enExample) |
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| CN112877291A (zh) | 2014-04-10 | 2021-06-01 | 西雅图儿童医院 (Dba西雅图儿童研究所) | 基因修饰的t细胞产品、其制备方法和用途 |
| HK1256087A1 (zh) | 2015-08-07 | 2019-09-13 | Seattle Children's Hospital, Dba Seattle Children's Research Institute | 用於实体瘤靶向的双特异性cart细胞 |
| ES2811500T3 (es) * | 2016-10-04 | 2021-03-12 | Prec Biosciences Inc | Dominios coestimuladores para su uso en células genéticamente modificadas |
| EP3548046A2 (en) | 2016-12-03 | 2019-10-09 | Juno Therapeutics, Inc. | Methods and compositions for use of therapeutic t cells in combination with kinase inhibitors |
| WO2018201144A1 (en) * | 2017-04-28 | 2018-11-01 | Precision Biosciences, Inc. | Methods for reducing dna-induced cytotoxicity and enhancing gene editing in primary cells |
| KR20200054160A (ko) | 2017-06-02 | 2020-05-19 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 요법을 사용한 치료를 위한 물품 제조 및 방법 |
| US11434290B2 (en) * | 2017-06-08 | 2022-09-06 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Chimeric antigen receptors with enhanced NFκB signaling |
| US10869888B2 (en) | 2018-04-17 | 2020-12-22 | Innovative Cellular Therapeutics CO., LTD. | Modified cell expansion and uses thereof |
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| US10918667B2 (en) | 2018-11-20 | 2021-02-16 | Innovative Cellular Therapeutics CO., LTD. | Modified cell expressing therapeutic agent and uses thereof |
| KR20240122580A (ko) | 2019-04-03 | 2024-08-12 | 프리시젼 바이오사이언시스 인코포레이티드 | 마이크로RNA-적응 shRNA(shRNAmiR)를 포함하는 유전자-변형 면역 세포 |
| US20220204994A1 (en) | 2019-04-05 | 2022-06-30 | Precision Biosciences, Inc. | Methods of preparing populations of genetically-modified immune cells |
| WO2021016608A1 (en) | 2019-07-25 | 2021-01-28 | Precision Biosciences, Inc. | Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus |
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| US20220411479A1 (en) | 2019-10-30 | 2022-12-29 | Precision Biosciences, Inc. | Cd20 chimeric antigen receptors and methods of use for immunotherapy |
| US20230036065A1 (en) | 2019-12-06 | 2023-02-02 | Precision Biosciences, Inc. | Methods for cancer immunotherapy |
| US20230346937A1 (en) * | 2020-02-13 | 2023-11-02 | Beijing Immunochina Pharmaceuticals Co., Ltd. | Optimization of chimeric antigen receptor |
| US12076343B2 (en) | 2020-02-19 | 2024-09-03 | Innovative Cellular Therapeutics Holdings, Ltd. | Engineered safety in cell therapy |
| US20230190780A1 (en) * | 2020-05-15 | 2023-06-22 | Precision Biosciences, Inc. | Methods for immunotherapy |
| WO2021231959A1 (en) * | 2020-05-15 | 2021-11-18 | Precision Biosciences, Inc. | Methods for immunotherapy |
| US12043654B2 (en) | 2020-06-02 | 2024-07-23 | Innovative Cellular Therapeutics Holdings, Ltd. | Anti-GCC antibody and CAR thereof for treating digestive system cancer |
| AU2021300615A1 (en) * | 2020-06-30 | 2023-02-02 | The University Court Of The University Of Edinburgh | Transgene expression system |
| US20260028412A1 (en) | 2020-08-10 | 2026-01-29 | Precision Biosciences, Inc. | Antibodies and fragments specific for b-cell maturation antigen and uses thereof |
| WO2022076547A1 (en) | 2020-10-07 | 2022-04-14 | Precision Biosciences, Inc. | Lipid nanoparticle compositions |
| WO2022165111A1 (en) | 2021-01-28 | 2022-08-04 | Precision Biosciences, Inc. | Modulation of tgf beta signaling in genetically-modified eukaryotic cells |
| WO2022266192A1 (en) * | 2021-06-16 | 2022-12-22 | Instil Bio, Inc. | Receptors providing targeted costimulation for adoptive cell therapy |
| WO2023064872A1 (en) | 2021-10-14 | 2023-04-20 | Precision Biosciences, Inc. | Combinations of anti-bcma car t cells and gamma secretase inhibitors |
| WO2023081767A1 (en) | 2021-11-05 | 2023-05-11 | Precision Biosciences, Inc. | Methods for immunotherapy |
| US20250009800A1 (en) | 2021-11-16 | 2025-01-09 | Precision Biosciences, Inc. | Methods for cancer immunotherapy |
| WO2023108150A1 (en) | 2021-12-10 | 2023-06-15 | Precision Biosciences, Inc. | Methods for cancer immunotherapy |
| IL313935A (en) | 2021-12-30 | 2024-08-01 | Tr1X Inc | CD4+ T cells expressing IL-10 chimeric antigen receptors and uses thereof |
| AU2024206812A1 (en) | 2023-01-05 | 2025-08-14 | Precision Biosciences, Inc. | Optimized engineered meganucleases having specificity for the human t cell receptor alpha constant region gene |
| WO2026015450A1 (en) | 2024-07-06 | 2026-01-15 | Tr1X, Inc. | Cd4+ t cells expressing il-10 and chimeric antigen receptors and uses thereof |
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| US20220411479A1 (en) * | 2019-10-30 | 2022-12-29 | Precision Biosciences, Inc. | Cd20 chimeric antigen receptors and methods of use for immunotherapy |
| US20230036065A1 (en) * | 2019-12-06 | 2023-02-02 | Precision Biosciences, Inc. | Methods for cancer immunotherapy |
-
2017
- 2017-10-04 ES ES17800638T patent/ES2811500T3/es active Active
- 2017-10-04 EP EP17800638.3A patent/EP3523326B1/en active Active
- 2017-10-04 JP JP2019518049A patent/JP6887492B6/ja active Active
- 2017-10-04 CA CA3039014A patent/CA3039014A1/en active Pending
- 2017-10-04 WO PCT/US2017/055133 patent/WO2018067697A1/en not_active Ceased
- 2017-10-04 DK DK20176441.2T patent/DK3757120T3/da active
- 2017-10-04 ES ES20176441T patent/ES2925644T3/es active Active
- 2017-10-04 EP EP22172338.0A patent/EP4115951A1/en active Pending
- 2017-10-04 AU AU2017338846A patent/AU2017338846B2/en active Active
- 2017-10-04 US US16/339,699 patent/US11286291B2/en active Active
- 2017-10-04 EP EP20176441.2A patent/EP3757120B8/en active Active
- 2017-10-04 DK DK17800638.3T patent/DK3523326T3/da active
-
2019
- 2019-10-11 US US16/600,074 patent/US10800833B2/en active Active
-
2020
- 2020-09-09 US US17/016,016 patent/US20200399346A1/en not_active Abandoned
- 2020-12-11 AU AU2020286323A patent/AU2020286323B2/en active Active
-
2021
- 2021-05-18 JP JP2021083808A patent/JP7106715B2/ja active Active
-
2022
- 2022-07-13 JP JP2022112159A patent/JP2022160443A/ja active Pending
-
2023
- 2023-05-10 AU AU2023202905A patent/AU2023202905A1/en not_active Abandoned
- 2023-08-21 US US18/453,022 patent/US20240018215A1/en active Pending
-
2024
- 2024-01-31 JP JP2024013162A patent/JP2024059633A/ja active Pending
-
2025
- 2025-02-03 AU AU2025200717A patent/AU2025200717A1/en active Pending
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