JP2019521704A5 - - Google Patents
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- JP2019521704A5 JP2019521704A5 JP2019516099A JP2019516099A JP2019521704A5 JP 2019521704 A5 JP2019521704 A5 JP 2019521704A5 JP 2019516099 A JP2019516099 A JP 2019516099A JP 2019516099 A JP2019516099 A JP 2019516099A JP 2019521704 A5 JP2019521704 A5 JP 2019521704A5
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- JP
- Japan
- Prior art keywords
- seq
- domain
- nucleic acid
- amino acid
- cdr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662346324P | 2016-06-06 | 2016-06-06 | |
| US62/346,324 | 2016-06-06 | ||
| US201662396767P | 2016-09-19 | 2016-09-19 | |
| US62/396,767 | 2016-09-19 | ||
| PCT/US2017/036178 WO2017214167A1 (en) | 2016-06-06 | 2017-06-06 | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019521704A JP2019521704A (ja) | 2019-08-08 |
| JP2019521704A5 true JP2019521704A5 (enExample) | 2020-07-16 |
| JP7070932B2 JP7070932B2 (ja) | 2022-05-18 |
Family
ID=59071115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019516099A Active JP7070932B2 (ja) | 2016-06-06 | 2017-06-06 | Ｂａｆｆ－ｒ標的化キメラ抗原受容体修飾ｔ細胞及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11161908B2 (enExample) |
| EP (1) | EP3464371B1 (enExample) |
| JP (1) | JP7070932B2 (enExample) |
| KR (6) | KR102522419B1 (enExample) |
| CN (2) | CN115960251A (enExample) |
| AU (2) | AU2017277269C1 (enExample) |
| CA (1) | CA3026640A1 (enExample) |
| IL (4) | IL308798A (enExample) |
| SG (1) | SG11201810887UA (enExample) |
| WO (1) | WO2017214167A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| EP3464371B1 (en) | 2016-06-06 | 2026-07-29 | City of Hope | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| JP2022515152A (ja) * | 2018-12-19 | 2022-02-17 | シティ・オブ・ホープ | Ｂａｆｆ－ｒ二重特異性ｔ細胞エンゲージャー抗体 |
| KR20210129125A (ko) * | 2019-02-20 | 2021-10-27 | 시티 오브 호프 | Baff-r/cd19 표적화된 키메라 항원 수용체-변형된 t 세포 및 그의 용도 |
| US12023354B2 (en) | 2019-05-31 | 2024-07-02 | Case Western Reserve University | Targeting B cell activating factor receptor (BAFF-R) using ligand-based chimeric antigen receptor (CAR)-T cells |
| WO2021064718A1 (en) * | 2019-10-01 | 2021-04-08 | Case Western Reserve University | Targeting b cell activating factor receptor (baff-r) using ligand-based chimeric antigen receptor (car)-t cells |
| WO2021163989A1 (en) | 2020-02-21 | 2021-08-26 | Yinnuolai Biotech Ltd. | Anti-baff receptor antibodies and uses thereof |
| CN111499723B (zh) * | 2020-05-28 | 2021-04-09 | 广州百暨基因科技有限公司 | 一种嵌合抗原受体及其应用 |
| EP4342913B1 (en) * | 2021-05-19 | 2025-12-17 | Shanghai Escugen Biotechnology Co., Ltd. | Chimeric antigen receptor molecule for specifically recognizing baff-r and application of chimeric antigen receptor molecule |
| WO2023010122A2 (en) | 2021-07-29 | 2023-02-02 | Sonoma Biotherapeutics, Inc. | Synovial extracellular matrix-specific chimeric antigen receptor for targeting regulatory t cells to treat autoimmune diseases |
| CA3257911A1 (en) * | 2022-06-01 | 2023-12-07 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Recombinant receptors binding to the B-cell activating factor receptor and their uses |
| CN116041515A (zh) * | 2022-09-20 | 2023-05-02 | 南京驯鹿医疗技术有限公司 | 一种靶向baff-r抗原的全人源抗体、单链抗体、抗原结合片段 |
| CN116143943B (zh) * | 2022-10-31 | 2023-09-01 | 邦恩泰(山东)生物医药科技集团股份有限公司 | 一种靶向baffr嵌合抗原受体、car-t细胞及应用 |
| WO2025006795A1 (en) * | 2023-06-30 | 2025-01-02 | Board Of Regents, The University Of Texas System | Tsyn-seq: a t cell synapse-based tumor antigen identification platform |
| CN117050195B (zh) * | 2023-10-13 | 2023-12-19 | 旭和（天津）医药科技有限公司 | 一种靶向baffr嵌合抗原受体、car-t细胞和应用 |
| WO2025089861A1 (ko) | 2023-10-27 | 2025-05-01 | 주식회사 엘지에너지솔루션 | 전극 분리 장치, 전극 이송 장치 및 전극 이송 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| ES2139598T3 (es) | 1990-07-10 | 2000-02-16 | Medical Res Council | Procedimientos para la produccion de miembros de parejas de union especifica. |
| JPH07503132A (ja) | 1991-12-17 | 1995-04-06 | ジェンファーム インターナショナル，インコーポレイティド | 異種抗体を産生することができるトランスジェニック非ヒト動物 |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| US6066718A (en) | 1992-09-25 | 2000-05-23 | Novartis Corporation | Reshaped monoclonal antibodies against an immunoglobulin isotype |
| AU2002368077B2 (en) | 2001-07-12 | 2010-03-04 | Jefferson Foote | Super humanized antibodies |
| BRPI0518994A2 (pt) * | 2004-12-31 | 2008-12-02 | Biogen Idec Inc | anticorpos ou polipeptÍdeos que se ligam a br3, seus usos e formulaÇÕes lÍquidas |
| WO2012012695A2 (en) * | 2010-07-23 | 2012-01-26 | Fred Hutchinson Cancer Research Center | A method for the treatment of obesity |
| US10117896B2 (en) * | 2012-10-05 | 2018-11-06 | The Trustees Of The University Of Pennsylvania | Use of a trans-signaling approach in chimeric antigen receptors |
| US20170158749A1 (en) | 2014-04-23 | 2017-06-08 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) and methods for making and using the same |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| KR20160016725A (ko) * | 2014-08-05 | 2016-02-15 | 주식회사 유영제약 | 암 세포에 과발현되는 IL13Rα2에 특이적으로 결합하는 키메라 항원 수용체로 변형된 T 세포 |
| US11136405B2 (en) * | 2016-06-06 | 2021-10-05 | Board Of Regents, The Unviersity Of Texas System | BAFF-R antibodies and uses thereof |
| EP3464371B1 (en) * | 2016-06-06 | 2026-07-29 | City of Hope | Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof |
-
2017
- 2017-06-06 EP EP17731026.5A patent/EP3464371B1/en active Active
- 2017-06-06 CN CN202210970028.2A patent/CN115960251A/zh active Pending
- 2017-06-06 IL IL308798A patent/IL308798A/en unknown
- 2017-06-06 JP JP2019516099A patent/JP7070932B2/ja active Active
- 2017-06-06 IL IL263385A patent/IL263385B2/en unknown
- 2017-06-06 US US16/307,443 patent/US11161908B2/en active Active
- 2017-06-06 KR KR1020227019986A patent/KR102522419B1/ko active Active
- 2017-06-06 IL IL311985A patent/IL311985A/en unknown
- 2017-06-06 CN CN201780035645.0A patent/CN109311991B/zh active Active
- 2017-06-06 KR KR1020237012104A patent/KR102584944B1/ko active Active
- 2017-06-06 KR KR1020227002646A patent/KR102410360B1/ko active Active
- 2017-06-06 KR KR1020257017399A patent/KR20250084978A/ko active Pending
- 2017-06-06 AU AU2017277269A patent/AU2017277269C1/en active Active
- 2017-06-06 KR KR1020197000160A patent/KR102356864B1/ko active Active
- 2017-06-06 SG SG11201810887UA patent/SG11201810887UA/en unknown
- 2017-06-06 IL IL297925A patent/IL297925B2/en unknown
- 2017-06-06 KR KR1020237032847A patent/KR102815802B1/ko active Active
- 2017-06-06 WO PCT/US2017/036178 patent/WO2017214167A1/en not_active Ceased
- 2017-06-06 CA CA3026640A patent/CA3026640A1/en active Pending
-
2021
- 2021-09-03 US US17/466,968 patent/US12215162B2/en active Active
-
2024
- 2024-06-20 AU AU2024204218A patent/AU2024204218A1/en active Pending
- 2024-11-25 US US18/958,507 patent/US20250092149A1/en active Pending
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