CA3026640A1 - Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof - Google Patents

Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof Download PDF

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Publication number
CA3026640A1
CA3026640A1 CA3026640A CA3026640A CA3026640A1 CA 3026640 A1 CA3026640 A1 CA 3026640A1 CA 3026640 A CA3026640 A CA 3026640A CA 3026640 A CA3026640 A CA 3026640A CA 3026640 A1 CA3026640 A1 CA 3026640A1
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Canada
Prior art keywords
cells
chain variable
baff
seq
variable region
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Pending
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CA3026640A
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English (en)
French (fr)
Inventor
Hong QIN
Larry W. Kwak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
The University of Texas System
City of Hope
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The University of Texas System
City of Hope
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Publication of CA3026640A1 publication Critical patent/CA3026640A1/en
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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CA3026640A 2016-06-06 2017-06-06 Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof Pending CA3026640A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662346324P 2016-06-06 2016-06-06
US62/346,324 2016-06-06
US201662396767P 2016-09-19 2016-09-19
US62/396,767 2016-09-19
PCT/US2017/036178 WO2017214167A1 (en) 2016-06-06 2017-06-06 Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof

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CA3026640A1 true CA3026640A1 (en) 2017-12-14

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US (3) US11161908B2 (enExample)
EP (1) EP3464371B1 (enExample)
JP (1) JP7070932B2 (enExample)
KR (6) KR102522419B1 (enExample)
CN (2) CN115960251A (enExample)
AU (2) AU2017277269C1 (enExample)
CA (1) CA3026640A1 (enExample)
IL (4) IL308798A (enExample)
SG (1) SG11201810887UA (enExample)
WO (1) WO2017214167A1 (enExample)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
EP2934532B1 (en) 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
CA3019835A1 (en) 2016-04-08 2017-10-12 Purdue Research Foundation Methods and compositions for car t cell therapy
EP3464371B1 (en) 2016-06-06 2026-07-29 City of Hope Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof
CN110582288B (zh) 2017-02-28 2024-09-20 恩多塞特公司 用于car t细胞疗法的组合物和方法
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