CA3026640A1 - Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof - Google Patents

Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof Download PDF

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Publication number
CA3026640A1
CA3026640A1 CA3026640A CA3026640A CA3026640A1 CA 3026640 A1 CA3026640 A1 CA 3026640A1 CA 3026640 A CA3026640 A CA 3026640A CA 3026640 A CA3026640 A CA 3026640A CA 3026640 A1 CA3026640 A1 CA 3026640A1
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Prior art keywords
cells
chain variable
baff
seq
variable region
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CA3026640A
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English (en)
French (fr)
Inventor
Hong QIN
Larry W. Kwak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
City of Hope
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University of Texas System
City of Hope
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Publication of CA3026640A1 publication Critical patent/CA3026640A1/en
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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CA3026640A 2016-06-06 2017-06-06 Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof Pending CA3026640A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662346324P 2016-06-06 2016-06-06
US62/346,324 2016-06-06
US201662396767P 2016-09-19 2016-09-19
US62/396,767 2016-09-19
PCT/US2017/036178 WO2017214167A1 (en) 2016-06-06 2017-06-06 Baff-r targeted chimeric antigen receptor-modified t-cells and uses thereof

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CA3026640A1 true CA3026640A1 (en) 2017-12-14

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US (3) US11161908B2 (enExample)
EP (1) EP3464371A1 (enExample)
JP (1) JP7070932B2 (enExample)
KR (6) KR102410360B1 (enExample)
CN (2) CN109311991B (enExample)
AU (2) AU2017277269C1 (enExample)
CA (1) CA3026640A1 (enExample)
IL (4) IL263385B2 (enExample)
SG (1) SG11201810887UA (enExample)
WO (1) WO2017214167A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3653212B1 (en) 2012-12-20 2023-04-26 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
EP3439675A4 (en) 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
JP7070932B2 (ja) * 2016-06-06 2022-05-18 シティ・オブ・ホープ Ｂａｆｆ－ｒ標的化キメラ抗原受容体修飾ｔ細胞及びその使用
ES3010559T3 (en) 2017-02-28 2025-04-03 Endocyte Inc Compositions and methods for car t cell therapy
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