DK3757120T3 - Co-stimulerende domæner til anvendelse i genetisk modificerede celler - Google Patents

Co-stimulerende domæner til anvendelse i genetisk modificerede celler Download PDF

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Publication number
DK3757120T3
DK3757120T3 DK20176441.2T DK20176441T DK3757120T3 DK 3757120 T3 DK3757120 T3 DK 3757120T3 DK 20176441 T DK20176441 T DK 20176441T DK 3757120 T3 DK3757120 T3 DK 3757120T3
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genetically modified
modified cells
stimulatory domains
stimulatory
domains
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DK20176441.2T
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Danish (da)
English (en)
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Derek Jantz
Aaron Martin
Daniel T Macleod
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Prec Biosciences Inc
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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DK20176441.2T 2016-10-04 2017-10-04 Co-stimulerende domæner til anvendelse i genetisk modificerede celler DK3757120T3 (da)

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US201662403880P 2016-10-04 2016-10-04
US201762501475P 2017-05-04 2017-05-04
US201762556199P 2017-09-08 2017-09-08
EP17800638.3A EP3523326B1 (en) 2016-10-04 2017-10-04 Co-stimulatory domains for use in genetically-modified cells

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DK3757120T3 true DK3757120T3 (da) 2022-07-25

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DK17800638.3T DK3523326T3 (da) 2016-10-04 2017-10-04 Samstimulerende domæner til anvendelse i genetisk modificerede celler

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US (4) US11286291B2 (enExample)
EP (3) EP3757120B8 (enExample)
JP (5) JP6887492B6 (enExample)
AU (4) AU2017338846B2 (enExample)
CA (1) CA3039014A1 (enExample)
DK (2) DK3757120T3 (enExample)
ES (2) ES2925644T3 (enExample)
WO (1) WO2018067697A1 (enExample)

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