|
US527565A
(en)
*
|
|
1894-10-16 |
|
tripp |
|
US3034507A
(en)
|
1960-05-10 |
1962-05-15 |
American Cyanamid Co |
Intracutaneous injection device
|
|
US3539465A
(en)
|
1968-10-08 |
1970-11-10 |
Ncr Co |
Encapsulation of hydrophilic liquid-in-oil emulsions
|
|
US3675766A
(en)
|
1970-02-04 |
1972-07-11 |
Sol Roy Rosenthal |
Multiple puncture injector device
|
|
US4897355A
(en)
|
1985-01-07 |
1990-01-30 |
Syntex (U.S.A.) Inc. |
N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
IE61148B1
(en)
*
|
1988-03-10 |
1994-10-05 |
Ici Plc |
Method of detecting nucleotide sequences
|
|
US5849686A
(en)
|
1991-03-11 |
1998-12-15 |
Creative Biomolecules, Inc. |
Morphogen-induced liver regeneration
|
|
US6800603B2
(en)
|
1991-03-11 |
2004-10-05 |
Curis, Inc. |
Morphogen-induced neural cell adhesion
|
|
US6949505B1
(en)
|
1991-03-11 |
2005-09-27 |
Curis, Inc. |
Morphogen-induced dendritic growth
|
|
US5674844A
(en)
|
1991-03-11 |
1997-10-07 |
Creative Biomolecules, Inc. |
Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
|
|
US6506729B1
(en)
|
1991-03-11 |
2003-01-14 |
Curis, Inc. |
Methods and compositions for the treatment and prevention of Parkinson's disease
|
|
US5656593A
(en)
|
1991-03-11 |
1997-08-12 |
Creative Biomolecules, Inc. |
Morphogen induced periodontal tissue regeneration
|
|
US5993434A
(en)
|
1993-04-01 |
1999-11-30 |
Genetronics, Inc. |
Method of treatment using electroporation mediated delivery of drugs and genes
|
|
US5843780A
(en)
|
1995-01-20 |
1998-12-01 |
Wisconsin Alumni Research Foundation |
Primate embryonic stem cells
|
|
US5711964A
(en)
|
1995-06-07 |
1998-01-27 |
United States Of America |
Method for the intracellular delivery of biomolecules using liposomes containing cationic lipids and vitamin D
|
|
EP0904093A4
(en)
|
1996-03-22 |
2004-11-17 |
Gen Hospital Corp |
THE ADMINISTRATION OF GROWTH FACTOR POLYPEPTIDES AFTER AN ISCHEMICAL OF THE CENTRAL NERVOUS SYSTEM OR A TRAUMA
|
|
US6498142B1
(en)
|
1996-05-06 |
2002-12-24 |
Curis, Inc. |
Morphogen treatment for chronic renal failure
|
|
US6602693B1
(en)
|
1996-07-03 |
2003-08-05 |
Clear Solutions Biotech, Inc. |
Gene encoding hyaluronan synthase
|
|
US6770291B2
(en)
|
1996-08-30 |
2004-08-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Liposome complexes for increased systemic delivery
|
|
CA2263705C
(en)
|
1996-08-19 |
2007-12-04 |
Nancy Smyth-Templeton |
Novel sandwich liposome complexes comprising a biologically active agent
|
|
TW520297B
(en)
|
1996-10-11 |
2003-02-11 |
Sequus Pharm Inc |
Fusogenic liposome composition and method
|
|
US6653104B2
(en)
|
1996-10-17 |
2003-11-25 |
Immunomedics, Inc. |
Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells
|
|
CA2277278A1
(en)
|
1997-01-10 |
1998-07-16 |
Life Technologies, Inc. |
Embryonic stem cell serum replacement
|
|
US6316260B1
(en)
|
1997-08-22 |
2001-11-13 |
Bernina Biosystems Gmbh |
Tetraether lipid derivatives and liposomes and lipid agglomerates containing tetraether lipid derivatives, and use thereof
|
|
EP1021549A2
(en)
|
1997-09-19 |
2000-07-26 |
Sequitur, Inc. |
SENSE mRNA THERAPY
|
|
DK1129064T3
(da)
|
1998-11-12 |
2008-04-28 |
Invitrogen Corp |
Transfektionsreagenser
|
|
GB9902000D0
(en)
|
1999-01-30 |
1999-03-17 |
Delta Biotechnology Ltd |
Process
|
|
DE60044084D1
(de)
|
1999-06-04 |
2010-05-12 |
Georgia Tech Res Inst |
Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten
|
|
US7621606B2
(en)
|
2001-08-27 |
2009-11-24 |
Advanced Cell Technology, Inc. |
Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies
|
|
US20110171185A1
(en)
|
1999-06-30 |
2011-07-14 |
Klimanskaya Irina V |
Genetically intact induced pluripotent cells or transdifferentiated cells and methods for the production thereof
|
|
US20020054895A1
(en)
|
1999-07-23 |
2002-05-09 |
Alwyn Company, Inc. |
Allantoin-containing skin cream
|
|
US6595947B1
(en)
|
2000-05-22 |
2003-07-22 |
Becton, Dickinson And Company |
Topical delivery of vaccines
|
|
KR100894767B1
(ko)
|
2000-09-26 |
2009-04-24 |
이데라 파마슈티칼즈, 인코포레이티드 |
화학적인 위치 변화에 의해 면역자극 올리고누클레오티드유사체의 면역자극 활성을 조절하는 방법
|
|
US7189759B2
(en)
|
2001-05-23 |
2007-03-13 |
Medicis Pharmaceutical Corporation |
Compositions for the treatment of pigmentation disorders and methods for their manufacture
|
|
EP1437403A4
(en)
|
2001-09-21 |
2004-10-27 |
Japan Science & Tech Corp |
METHOD FOR PATTERNING REPROGRAMMING FACTOR, METHOD OF PATTERNED REPROGRAMMING FACTOR, METHOD FOR USE OF REPROGRAMMING FACTOR, METHOD FOR DIFFERENTIATING AND SIFE-INGENATING FAN
|
|
CA2463914A1
(en)
|
2001-10-18 |
2003-04-24 |
Ixion Biotechnology, Inc. |
Conversion of liver stem and progenitor cells to pancreatic functional cells
|
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
GB0202149D0
(en)
|
2002-01-30 |
2002-03-20 |
Univ Edinburgh |
Pluripotency determining factors and uses thereof
|
|
US20030186249A1
(en)
|
2002-04-01 |
2003-10-02 |
Zairen Sun |
Human TARPP genes and polypeptides
|
|
JP3785508B2
(ja)
|
2002-04-15 |
2006-06-14 |
学校法人慶應義塾 |
遺伝子治療における免疫応答を解析できる実験モデルマウス
|
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
|
US7737182B2
(en)
|
2002-08-09 |
2010-06-15 |
Taisho Pharmaceutical Co., Ltd. |
Pharmaceuticals for xerosis
|
|
US7541344B2
(en)
|
2003-06-03 |
2009-06-02 |
Eli Lilly And Company |
Modulation of survivin expression
|
|
EP1691780A2
(en)
|
2003-11-21 |
2006-08-23 |
Alza Corporation |
Gene delivery mediated by liposome-dna complex with cleavable peg surface modification
|
|
US7682828B2
(en)
|
2003-11-26 |
2010-03-23 |
Whitehead Institute For Biomedical Research |
Methods for reprogramming somatic cells
|
|
BRPI0514641A
(pt)
|
2004-09-08 |
2008-06-17 |
Wisconsin Alumni Res Found |
cultivação das células tronco embriÈnica humana
|
|
EP1791948B1
(en)
|
2004-09-08 |
2012-03-14 |
Wisconsin Alumni Research Foundation |
Medium and culture of embryonic stem cells
|
|
US20090202638A2
(en)
|
2004-10-27 |
2009-08-13 |
New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery |
Bmp gene and fusion protein
|
|
AU2006208199B2
(en)
|
2005-01-25 |
2012-06-07 |
Cell Therapeutics, Inc. |
Conjugates of biologically active proteins having a modified in vivo half-life
|
|
US7696318B2
(en)
|
2005-07-13 |
2010-04-13 |
Novo Nordisk Health Care Ag |
Host cell protein knock-out cells for production of therapeutic proteins
|
|
SG10201508995QA
(en)
|
2005-07-26 |
2015-11-27 |
Sangamo Biosciences Inc |
Targeted integration and expression of exogenous nucleic acid sequences
|
|
US8323666B2
(en)
|
2005-08-01 |
2012-12-04 |
Allergan, Inc. |
Botulinum toxin compositions
|
|
US9012219B2
(en)
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
|
LT2578685T
(lt)
|
2005-08-23 |
2019-06-10 |
The Trustees Of The University Of Pennsylvania |
Rnr, apimančios modifikuotus nukleozidus ir jų panaudojimo būdai
|
|
US8476070B2
(en)
|
2005-08-29 |
2013-07-02 |
Technion Research & Development Foundation Limited |
Media for culturing stem cells
|
|
TW200732347A
(en)
|
2005-10-06 |
2007-09-01 |
Trophogen Inc |
VEGF analogs and methods of use
|
|
WO2007069666A1
(ja)
|
2005-12-13 |
2007-06-21 |
Kyoto University |
核初期化因子
|
|
US8129187B2
(en)
|
2005-12-13 |
2012-03-06 |
Kyoto University |
Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
|
|
US8278104B2
(en)
|
2005-12-13 |
2012-10-02 |
Kyoto University |
Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
|
|
US20100168000A1
(en)
|
2005-12-22 |
2010-07-01 |
Peter Kiessling |
Octanoate-Reduced Human Albumin
|
|
US7658728B2
(en)
|
2006-01-10 |
2010-02-09 |
Yuzhakov Vadim V |
Microneedle array, patch, and applicator for transdermal drug delivery
|
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
|
GB0623635D0
(en)
|
2006-11-27 |
2007-01-03 |
Stem Cell Sciences Uk Ltd |
Pluripotent cell growth media
|
|
US7785301B2
(en)
|
2006-11-28 |
2010-08-31 |
Vadim V Yuzhakov |
Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection
|
|
CA2671850A1
(en)
|
2006-12-08 |
2008-06-19 |
Massachusetts Institute Of Technology |
Delivery of nanoparticles and/or agents to cells
|
|
CN101200758A
(zh)
|
2006-12-15 |
2008-06-18 |
华中科技大学 |
一种检测col7a1基因突变的方法及其用途
|
|
US10829733B2
(en)
|
2007-01-04 |
2020-11-10 |
Biolamina Ab |
Composition and method for enabling proliferation of pluripotent human stem cells
|
|
EP2099911A2
(en)
|
2007-01-11 |
2009-09-16 |
Yale University |
Compositions and methods for targeted inactivation of hiv cell surface receptors
|
|
US9249423B2
(en)
|
2007-02-02 |
2016-02-02 |
Yale University |
Method of de-differentiating and re-differentiating somatic cells using RNA
|
|
US8859229B2
(en)
|
2007-02-02 |
2014-10-14 |
Yale University |
Transient transfection with RNA
|
|
SG193652A1
(en)
|
2007-03-23 |
2013-10-30 |
Wisconsin Alumni Res Found |
Somatic cell reprogramming
|
|
EP3878949B1
(en)
|
2007-04-07 |
2025-06-04 |
Whitehead Institute for Biomedical Research |
Reprogramming of somatic cells
|
|
JP2008307007A
(ja)
|
2007-06-15 |
2008-12-25 |
Bayer Schering Pharma Ag |
出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
|
|
WO2008151845A2
(en)
*
|
2007-06-15 |
2008-12-18 |
Charite - Universitätsmedizin Berlin |
Methods for producing glycosylated human alpha-1 antitrypsin (a1at) in mammalian host cells
|
|
JP5558097B2
(ja)
|
2007-12-10 |
2014-07-23 |
国立大学法人京都大学 |
効率的な核初期化方法
|
|
US20110021335A1
(en)
|
2007-12-14 |
2011-01-27 |
Pascal Jozef Paul Buskens |
Sol-gel process with a protected catalyst
|
|
EP2072618A1
(en)
|
2007-12-14 |
2009-06-24 |
Johannes Gutenberg-Universität Mainz |
Use of RNA for reprogramming somatic cells
|
|
EP2222696A1
(en)
|
2007-12-21 |
2010-09-01 |
Stryker Corporation |
Bmp mutants with decreased susceptibility to noggin
|
|
CN102027105B
(zh)
|
2008-03-17 |
2015-03-11 |
斯克里普斯研究所 |
用于产生诱导的多能干细胞的组合化学遗传方法
|
|
US20110045001A1
(en)
|
2008-03-28 |
2011-02-24 |
Biontex Laboratories Gmbh |
Transfection results of non-viral gene delivery systems by influencing of the innate immune system
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
JP2011160661A
(ja)
|
2008-06-02 |
2011-08-25 |
Kyowa Hakko Kirin Co Ltd |
血球細胞の初期化法
|
|
DK2297307T3
(en)
|
2008-06-04 |
2016-07-25 |
Cellular Dynamics Int Inc |
PROCEDURES FOR THE MANUFACTURE OF IPS CELLS USING NON-VIRAL METHODS
|
|
GB2460552B
(en)
|
2008-06-05 |
2011-09-07 |
Iti Scotland Ltd |
Stem cell culture media and methods
|
|
US8669048B2
(en)
|
2008-06-24 |
2014-03-11 |
Parkinson's Institute |
Pluripotent cell lines and methods of use thereof
|
|
US20100184033A1
(en)
|
2008-07-16 |
2010-07-22 |
West Michael D |
Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby
|
|
EP2151248A1
(en)
|
2008-07-30 |
2010-02-10 |
Johann Bauer |
Improved pre-mRNA trans-splicing molecule (RTM) molecules and their uses
|
|
EP2326711A2
(en)
|
2008-08-20 |
2011-06-01 |
VIRxSYS Corporation |
Compositions and methods for generation of pluripotent stem cells
|
|
US20100076057A1
(en)
|
2008-09-23 |
2010-03-25 |
Northwestern University |
TARGET DNA INTERFERENCE WITH crRNA
|
|
CN105802917A
(zh)
|
2008-10-24 |
2016-07-27 |
威斯康星校友研究基金会 |
通过非病毒重编程获得的多潜能干细胞
|
|
CN105999538A
(zh)
|
2008-11-18 |
2016-10-12 |
3M创新有限公司 |
空心微针阵列和方法
|
|
ES2561949T3
(es)
|
2008-11-21 |
2016-03-01 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Reprogramación de células hacia un estado pluripotente
|
|
EP2206723A1
(en)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modular DNA-binding domains
|
|
US20110239315A1
(en)
|
2009-01-12 |
2011-09-29 |
Ulla Bonas |
Modular dna-binding domains and methods of use
|
|
EP2412800A1
(en)
|
2010-07-29 |
2012-02-01 |
Koninklijke Nederlandse Akademie van Wetenschappen |
Liver organoid, uses thereof and culture method for obtaining them
|
|
WO2010093655A2
(en)
|
2009-02-10 |
2010-08-19 |
University Of Dayton |
Enhanced method for producing stem-like cells from somatic cells
|
|
US10894944B2
(en)
|
2009-04-10 |
2021-01-19 |
Monash University |
Cell culture media
|
|
US20100273220A1
(en)
|
2009-04-22 |
2010-10-28 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
|
EP3904505A1
(en)
|
2009-04-22 |
2021-11-03 |
Viacyte, Inc. |
Cell compositions derived from dedifferentiated reprogrammed cells
|
|
US10837020B2
(en)
*
|
2009-04-22 |
2020-11-17 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long RNA molecules
|
|
EP2251437B1
(en)
|
2009-05-13 |
2013-12-04 |
Hannelore Breitenbach-Koller |
Method for identifying compounds that control the translational activity of ribosomal proteins in differential mRNA expression
|
|
US8496941B2
(en)
|
2009-06-03 |
2013-07-30 |
National Institute Of Advanced Industrial Science And Technology |
Vectors for generating pluripotent stem cells and methods of producing pluripotent stem cells using the same
|
|
WO2010148050A2
(en)
|
2009-06-16 |
2010-12-23 |
Curna, Inc. |
Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
|
|
KR20140119197A
(ko)
|
2009-07-31 |
2014-10-08 |
에트리스 게엠베하 |
단백질 발현을 위한 비변형된 뉴클레오티드 및 변형된 뉴클레오티드의 조합을 가진 rna
|
|
US8586526B2
(en)
|
2010-05-17 |
2013-11-19 |
Sangamo Biosciences, Inc. |
DNA-binding proteins and uses thereof
|
|
US9295697B2
(en)
|
2009-11-04 |
2016-03-29 |
Cellular Dynamics International, Inc. |
Episomal reprogramming with chemicals
|
|
CN102712904A
(zh)
|
2009-11-11 |
2012-10-03 |
桑福德—伯恩哈姆医学研究协会 |
用于产生和调节iPS细胞的方法及其组合物
|
|
US20130189741A1
(en)
|
2009-12-07 |
2013-07-25 |
Cellscript, Inc. |
Compositions and methods for reprogramming mammalian cells
|
|
US8808982B2
(en)
|
2009-12-07 |
2014-08-19 |
Cellscript, Llc |
Compositions and methods for reprogramming eukaryotic cells
|
|
US8586363B2
(en)
|
2009-12-10 |
2013-11-19 |
Regents Of The University Of Minnesota |
TAL effector-mediated DNA modification
|
|
US8557972B2
(en)
|
2009-12-21 |
2013-10-15 |
University Of Washington Through Its Center For Commercialization |
Compositions and methods for transfection of RNA and controlled stabilization of transfected RNA
|
|
CA2788635A1
(en)
|
2010-02-01 |
2011-08-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
Enhanced efficiency of induced pluripotent stem cell generation
|
|
US20140194482A1
(en)
|
2010-02-02 |
2014-07-10 |
Scioderm, Inc. |
Compositions and methods of treatment of inflammatory skin conditions using allantoin
|
|
JPWO2011102532A1
(ja)
|
2010-02-16 |
2013-06-17 |
国立大学法人九州大学 |
誘導肝細胞
|
|
WO2011110886A1
(en)
|
2010-03-09 |
2011-09-15 |
Biolamina Ab |
Composition and method for enabling proliferation of pluripotent human stem cells
|
|
CA3122219A1
(en)
|
2010-04-16 |
2011-10-20 |
The Children's Hospital Corporation |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
|
CN102234627B
(zh)
|
2010-04-30 |
2015-06-03 |
中国科学院广州生物医药与健康研究院 |
一种培养基添加剂及其应用
|
|
US9725695B2
(en)
|
2010-05-05 |
2017-08-08 |
The Regents Of The University Of California |
Stem cell defined media for xeno-free and feeder free conditions and uses thereof
|
|
US8048675B1
(en)
|
2010-05-12 |
2011-11-01 |
Ipierian, Inc. |
Integration-free human induced pluripotent stem cells from blood
|
|
CA2799095A1
(en)
|
2010-05-12 |
2011-11-17 |
Cellectis |
Meganuclease variants cleaving a dna target sequence from the dystrophin gene and uses thereof
|
|
EP2392208B1
(en)
|
2010-06-07 |
2016-05-04 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use
|
|
EP2580331A4
(en)
|
2010-06-14 |
2013-11-27 |
Univ Iowa State Res Found Inc |
NUCLEASE ACTIVITY OF THE TAL EFFECTOR AND FUSION PROTEIN FOKI
|
|
CA2807418C
(en)
|
2010-08-05 |
2017-04-04 |
Wisconsin Alumni Research Foundation |
Simplified basic media for human pluripotent cell culture
|
|
CA2807552A1
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
US20140127814A1
(en)
|
2010-08-10 |
2014-05-08 |
Srinivasan Chandrasegaran |
Generation and use of pluripotent stem cells
|
|
GB201014169D0
(en)
*
|
2010-08-25 |
2010-10-06 |
Cambridge Entpr Ltd |
In vitro hepatic differentiation
|
|
US9447408B2
(en)
|
2010-09-14 |
2016-09-20 |
Kyoto University |
Method of efficiently establishing induced pluripotent stem cells
|
|
EP4108671B1
(en)
|
2010-10-01 |
2024-11-20 |
ModernaTX, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
|
WO2012048213A1
(en)
|
2010-10-08 |
2012-04-12 |
Regents Of The University Of Minnesota |
A method to increase gene targeting frequency
|
|
US9637732B2
(en)
|
2010-11-04 |
2017-05-02 |
Kyoto University |
Method of efficiently establishing induced pluripotent stem cells
|
|
WO2012094132A1
(en)
|
2011-01-05 |
2012-07-12 |
Sangamo Biosciences, Inc. |
Methods and compositions for gene correction
|
|
AU2012225497A1
(en)
|
2011-03-07 |
2013-10-24 |
Massachusetts Institute Of Technology |
Methods for transfecting cells with nucleic acids
|
|
US8710200B2
(en)
|
2011-03-31 |
2014-04-29 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids encoding a modified erythropoietin and their expression
|
|
WO2012131090A1
(en)
|
2011-03-31 |
2012-10-04 |
Galderma Research & Development |
Method for treatment of xeroderma pigmentosum
|
|
EP2694660B1
(en)
|
2011-04-03 |
2018-08-08 |
The General Hospital Corporation |
Efficient protein expression in vivo using modified rna (mod-rna)
|
|
WO2012138927A2
(en)
|
2011-04-05 |
2012-10-11 |
Philippe Duchateau |
Method for the generation of compact tale-nucleases and uses thereof
|
|
PT2702160T
(pt)
*
|
2011-04-27 |
2020-07-30 |
Amyris Inc |
Métodos para modificação genómica
|
|
WO2012174224A2
(en)
|
2011-06-17 |
2012-12-20 |
Calando Pharmaceuticals, Inc. |
Methods for administering nucleic acid-based therapeutics
|
|
WO2012176015A1
(en)
|
2011-06-24 |
2012-12-27 |
Leo Pharma A/S |
Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate
|
|
US9862926B2
(en)
|
2011-06-27 |
2018-01-09 |
Cellscript, Llc. |
Inhibition of innate immune response
|
|
EP2732029B1
(en)
|
2011-07-11 |
2019-01-16 |
FUJIFILM Cellular Dynamics, Inc. |
Methods for cell reprogramming and genome engineering
|
|
JP2014524241A
(ja)
|
2011-08-03 |
2014-09-22 |
ロータス ティシュー リペア インコーポレイテッド |
コラーゲン7及び関連する方法
|
|
CA3186126A1
(en)
*
|
2011-09-21 |
2013-03-28 |
Sangamo Biosciences, Inc. |
Methods and compositions for regulation of transgene expression
|
|
ES2911677T3
(es)
|
2011-10-03 |
2022-05-20 |
Modernatx Inc |
Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
|
|
US9340783B2
(en)
|
2011-10-11 |
2016-05-17 |
Inserm (Institut National De La Sante Et De La Recherche Medicale |
Exon skipping therapy for dystrophic epidermolysis bullosa
|
|
CN104105504A
(zh)
|
2011-10-11 |
2014-10-15 |
诺华股份有限公司 |
重组多顺反子核酸分子
|
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
|
KR20250035015A
(ko)
|
2011-12-05 |
2025-03-11 |
팩터 바이오사이언스 인크. |
세포를 형질감염시키는 방법들 및 생성물들
|
|
WO2013090186A1
(en)
|
2011-12-14 |
2013-06-20 |
modeRNA Therapeutics |
Modified nucleic acids, and acute care uses thereof
|
|
MX2014007233A
(es)
|
2011-12-16 |
2015-02-04 |
Moderna Therapeutics Inc |
Composiciones de nucleosidos, nucleotidos y acidos nucleicos modificados.
|
|
EP2793906A4
(en)
|
2011-12-21 |
2016-01-13 |
Moderna Therapeutics Inc |
METHOD FOR INCREASING THE LIFE-LIFE OR DURABILITY OF AN ORGAN OR ORGAN EXPLOITATE
|
|
DK3421601T3
(da)
|
2011-12-30 |
2020-02-24 |
Cellscript Llc |
Fremstilling og anvendelse af in-vitro-syntetiseret ssRNA til indføring i pattedyrceller med henblik på at inducere en biologisk eller biokemisk effekt
|
|
WO2013142514A1
(en)
*
|
2012-03-19 |
2013-09-26 |
Isis Pharmaceuticals, Inc. |
Methods and compositions for modulating alpha-1-antitrypsin expression
|
|
WO2013151663A1
(en)
*
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of membrane proteins
|
|
US20130274129A1
(en)
|
2012-04-04 |
2013-10-17 |
Geneart Ag |
Tal-effector assembly platform, customized services, kits and assays
|
|
SG11201406787TA
(en)
|
2012-04-20 |
2014-12-30 |
Agency Science Tech & Res |
Rnai-based therapies for cardiomyopathies, muscular dystrophies and laminopathies
|
|
CN104718283A
(zh)
|
2012-04-24 |
2015-06-17 |
布里格姆及妇女医院股份有限公司 |
从头生成多能细胞
|
|
US10155929B2
(en)
|
2012-05-13 |
2018-12-18 |
Allele Biotechnology & Pharmaceuticals, Inc. |
Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
|
|
US10119150B2
(en)
|
2012-05-13 |
2018-11-06 |
Allele Biotechnology & Pharmaceuticals, Inc. |
Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA
|
|
ES2951822T3
(es)
|
2012-05-13 |
2023-10-25 |
Allele Biotechnology & Pharmaceuticals Inc |
Derivación sin alimentadores de células madre pluripotentes inducidas humanas con ARN mensajero sintético
|
|
WO2014015314A1
(en)
|
2012-07-19 |
2014-01-23 |
University Of Southern California |
Recombinant c7 and methods of use
|
|
WO2014059173A2
(en)
*
|
2012-10-10 |
2014-04-17 |
Sangamo Biosciences, Inc. |
T cell modifying compounds and uses thereof
|
|
WO2014071219A1
(en)
*
|
2012-11-01 |
2014-05-08 |
Factor Bioscience Inc. |
Methods and products for expressing proteins in cells
|
|
SI2959005T1
(sl)
|
2013-02-22 |
2022-01-31 |
The Board Of Trustees Of The Leland Stanford Junior University |
Medicinska uporaba v zvezi z ekstenzijo telomera
|
|
ES2739913T3
(es)
|
2013-02-22 |
2020-02-04 |
Curevac Ag |
Combinación de vacunación e inhibición de la ruta PD-1
|
|
AU2014218807A1
(en)
|
2013-02-22 |
2015-09-03 |
Cellular Dynamics International, Inc. |
Hepatocyte production via forward programming by combined genetic and chemical engineering
|
|
ES2750550T3
(es)
|
2013-03-01 |
2020-03-26 |
Univ Minnesota |
Corrección de gen a base de TALEN
|
|
SG11201510284XA
(en)
*
|
2013-06-17 |
2016-01-28 |
Broad Inst Inc |
Delivery and use of the crispr-cas systems, vectors and compositions for hepatic targeting and therapy
|
|
EP3444350B1
(en)
|
2013-07-03 |
2021-12-01 |
Dicerna Pharmaceuticals, Inc. |
Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded rna
|
|
WO2015038075A1
(en)
|
2013-09-16 |
2015-03-19 |
Agency For Science, Technology And Research |
Method
|
|
US11053481B2
(en)
*
|
2013-12-12 |
2021-07-06 |
President And Fellows Of Harvard College |
Fusions of Cas9 domains and nucleic acid-editing domains
|
|
CA2933561A1
(en)
|
2013-12-12 |
2015-06-18 |
Life Technologies Corporation |
Membrane-penetrating peptides to enhanced transfection and compositions and methods for using same
|
|
EP3053585A1
(en)
|
2013-12-13 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Alternative nucleic acid molecules and uses thereof
|
|
AU2015210769B2
(en)
*
|
2014-01-31 |
2019-02-07 |
Factor Bioscience Inc. |
Methods and products for nucleic acid production and delivery
|
|
PT3105317T
(pt)
*
|
2014-02-14 |
2019-02-27 |
Cellectis |
Células para imunoterapia manipuladas para atuar sobre antigénios presentes tanto em células imunitárias como em células patológicas
|
|
KR20250102123A
(ko)
*
|
2014-04-18 |
2025-07-04 |
에디타스 메디신, 인코포레이티드 |
암 면역요법을 위한 crispr-cas-관련 방법, 조성물 및 구성성분
|
|
PT3134131T
(pt)
*
|
2014-04-23 |
2022-03-24 |
Modernatx Inc |
Vacinas de ácidos nucleicos
|
|
KR20250075716A
(ko)
*
|
2014-12-29 |
2025-05-28 |
노파르티스 아게 |
키메라 항원 수용체-발현 세포를 제조하는 방법
|
|
EP4406585A3
(en)
|
2015-02-13 |
2024-10-23 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
EP3967758A1
(en)
*
|
2015-12-01 |
2022-03-16 |
CRISPR Therapeutics AG |
Materials and methods for treatment of alpha-1 antitrypsin deficiency
|
|
IL291971B2
(en)
*
|
2016-03-04 |
2025-04-01 |
Editas Medicine Inc |
CRISPR–CPF1 related methods, compositions and components for cancer immunotherapy
|
|
US11512311B2
(en)
*
|
2016-03-25 |
2022-11-29 |
Editas Medicine, Inc. |
Systems and methods for treating alpha 1-antitrypsin (A1AT) deficiency
|
|
WO2018035377A1
(en)
*
|
2016-08-17 |
2018-02-22 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|