JP2017510542A5 - - Google Patents
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- JP2017510542A5 JP2017510542A5 JP2016533700A JP2016533700A JP2017510542A5 JP 2017510542 A5 JP2017510542 A5 JP 2017510542A5 JP 2016533700 A JP2016533700 A JP 2016533700A JP 2016533700 A JP2016533700 A JP 2016533700A JP 2017510542 A5 JP2017510542 A5 JP 2017510542A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- gene editing
- gene
- editing protein
- synthetic rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000010362 genome editing Methods 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 4
- 101100114361 Arabidopsis thaliana COL7 gene Proteins 0.000 claims 3
- 101710163270 Nuclease Proteins 0.000 claims 3
- 208000010975 Dystrophic epidermolysis bullosa Diseases 0.000 claims 2
- 208000004298 epidermolysis bullosa dystrophica Diseases 0.000 claims 2
- 210000002510 keratinocyte Anatomy 0.000 claims 2
- 108091033409 CRISPR Proteins 0.000 claims 1
- 238000010354 CRISPR gene editing Methods 0.000 claims 1
- 102000014914 Carrier Proteins Human genes 0.000 claims 1
- 230000004568 DNA-binding Effects 0.000 claims 1
- 108010008532 Deoxyribonuclease I Proteins 0.000 claims 1
- 102000007260 Deoxyribonuclease I Human genes 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 108091036407 Polyadenylation Proteins 0.000 claims 1
- 108010017070 Zinc Finger Nucleases Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000005782 double-strand break Effects 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 230000005783 single-strand break Effects 0.000 claims 1
- 230000002103 transcriptional effect Effects 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461934397P | 2014-01-31 | 2014-01-31 | |
| US61/934,397 | 2014-01-31 | ||
| US201462038608P | 2014-08-18 | 2014-08-18 | |
| US62/038,608 | 2014-08-18 | ||
| US201462069667P | 2014-10-28 | 2014-10-28 | |
| US62/069,667 | 2014-10-28 | ||
| PCT/US2015/013949 WO2015117021A1 (en) | 2014-01-31 | 2015-01-30 | Methods and products for nucleic acid production and delivery |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020128881A Division JP7235702B2 (ja) | 2014-01-31 | 2020-07-30 | 核酸生成及び送達のための方法及び製品 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017510542A JP2017510542A (ja) | 2017-04-13 |
| JP2017510542A5 true JP2017510542A5 (enExample) | 2018-03-08 |
Family
ID=53757787
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533700A Pending JP2017510542A (ja) | 2014-01-31 | 2015-01-30 | 核酸生成及び送達のための方法及び製品 |
| JP2020128881A Active JP7235702B2 (ja) | 2014-01-31 | 2020-07-30 | 核酸生成及び送達のための方法及び製品 |
| JP2023026873A Pending JP2023075165A (ja) | 2014-01-31 | 2023-02-24 | 核酸生成及び送達のための方法及び製品 |
| JP2024151104A Pending JP2025003953A (ja) | 2014-01-31 | 2024-09-03 | 核酸生成及び送達のための方法及び製品 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020128881A Active JP7235702B2 (ja) | 2014-01-31 | 2020-07-30 | 核酸生成及び送達のための方法及び製品 |
| JP2023026873A Pending JP2023075165A (ja) | 2014-01-31 | 2023-02-24 | 核酸生成及び送達のための方法及び製品 |
| JP2024151104A Pending JP2025003953A (ja) | 2014-01-31 | 2024-09-03 | 核酸生成及び送達のための方法及び製品 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US9770489B2 (enExample) |
| EP (3) | EP3099801B1 (enExample) |
| JP (4) | JP2017510542A (enExample) |
| KR (3) | KR102415811B1 (enExample) |
| CN (1) | CN105940110A (enExample) |
| AU (3) | AU2015210769B2 (enExample) |
| BR (1) | BR112016017736A2 (enExample) |
| CA (1) | CA2937036A1 (enExample) |
| DK (1) | DK3690056T5 (enExample) |
| ES (2) | ES2939542T3 (enExample) |
| FI (1) | FI3690056T3 (enExample) |
| MX (2) | MX372651B (enExample) |
| RU (2) | RU2714404C2 (enExample) |
| WO (1) | WO2015117021A1 (enExample) |
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