JP2019516757A5 - - Google Patents
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- JP2019516757A5 JP2019516757A5 JP2018561543A JP2018561543A JP2019516757A5 JP 2019516757 A5 JP2019516757 A5 JP 2019516757A5 JP 2018561543 A JP2018561543 A JP 2018561543A JP 2018561543 A JP2018561543 A JP 2018561543A JP 2019516757 A5 JP2019516757 A5 JP 2019516757A5
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- Prior art keywords
- compound
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- membered
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022164864A JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2016083124 | 2016-05-24 | ||
| CNPCT/CN2016/083124 | 2016-05-24 | ||
| PCT/US2017/034320 WO2017205536A2 (en) | 2016-05-24 | 2017-05-24 | Therapeutic compounds and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022164864A Division JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019516757A JP2019516757A (ja) | 2019-06-20 |
| JP2019516757A5 true JP2019516757A5 (enExample) | 2020-07-09 |
| JP7160688B2 JP7160688B2 (ja) | 2022-10-25 |
Family
ID=59014798
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561543A Expired - Fee Related JP7160688B2 (ja) | 2016-05-24 | 2017-05-24 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
| JP2022164864A Pending JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022164864A Pending JP2023002643A (ja) | 2016-05-24 | 2022-10-13 | Ｃｂｐ／ｅｐ３００の複素環式インヒビターおよびがんの処置におけるそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10696655B2 (enExample) |
| EP (2) | EP4067347B1 (enExample) |
| JP (2) | JP7160688B2 (enExample) |
| CN (2) | CN109476641B (enExample) |
| MA (1) | MA45122A (enExample) |
| WO (1) | WO2017205536A2 (enExample) |
Families Citing this family (40)
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|---|---|---|---|---|
| WO2017190145A1 (en) | 2016-04-29 | 2017-11-02 | Icahn School Of Medicine At Mount Sinai | Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
| WO2017205536A2 (en) | 2016-05-24 | 2017-11-30 | Genentech, Inc. | Therapeutic compounds and uses thereof |
| US11040027B2 (en) | 2017-01-17 | 2021-06-22 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| JP7311228B2 (ja) * | 2017-06-30 | 2023-07-19 | ベイジン タイド ファーマシューティカル カンパニー リミテッド | Ｒｈｏ－関連プロテインキナーゼ阻害剤、それを含む医薬組成物並びにその調製方法及び使用 |
| US10329282B2 (en) * | 2017-06-30 | 2019-06-25 | Beijing Tide Pharmaceutical Co., Ltd. | Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof |
| WO2019000683A1 (zh) | 2017-06-30 | 2019-01-03 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
| WO2019055877A1 (en) | 2017-09-15 | 2019-03-21 | Forma Therapeutics, Inc. | TETRAHYDROIMIDAZO QUINOLINE COMPOSITIONS AS INHIBITORS OF CBP / P300 |
| AU2019220662B2 (en) | 2018-02-16 | 2024-06-13 | Constellation Pharmaceuticals, Inc. | P300/CBP HAT inhibitors |
| WO2019161157A1 (en) * | 2018-02-16 | 2019-08-22 | Constellation Pharmceuticals, Inc. | P300/cbp hat inhibitors |
| CA3095367A1 (en) | 2018-03-29 | 2019-10-03 | Board Of Regents, The University Of Texas System | Imidazopiperazine inhibitors of transcription activating proteins |
| WO2019195846A1 (en) | 2018-04-06 | 2019-10-10 | Board Of Regents, The University Of Texas System | Imidazopiperazinone inhibitors of transcription activating proteins |
| EP3782995B1 (en) * | 2018-04-20 | 2023-11-22 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences | Spiro condensed imidazoline-2,4-dione derivatives as histone acetyltransferase inhibitors for the treatment of cancer diseases |
| WO2019220412A2 (en) * | 2018-05-18 | 2019-11-21 | Janssen Biotech, Inc. | Safe and effective method of treating lupus with anti-il12/il23 antibody |
| IL279734B2 (en) | 2018-06-29 | 2024-11-01 | Forma Therapeutics Inc | Inhibiting creb binding protein (cbp) |
| US11420977B2 (en) | 2018-08-02 | 2022-08-23 | Trustees Of Boston University | Late SV40 (LSF) inhibitors |
| CN109336836A (zh) * | 2018-11-23 | 2019-02-15 | 厦门大学 | Carm1小分子抑制剂的化合物及用途 |
| HRP20241237T1 (hr) * | 2019-02-27 | 2024-12-06 | Constellation Pharmaceuticals, Inc. | Derivati n-(piridinil)acetamida kao inhibitori p300/cbp hat i postupci za njihovu upotrebu |
| CN113646002A (zh) * | 2019-02-27 | 2021-11-12 | 上海睿跃生物科技有限公司 | 环amp反应元件结合蛋白(cbp)和/或300kda腺病毒e1a结合蛋白(p300)降解化合物和使用方法 |
| TW202102494A (zh) | 2019-03-15 | 2021-01-16 | 美商弗瑪治療公司 | 抑制環amp-反應元件-結合蛋白(creb) |
| CN111763180B (zh) * | 2019-04-02 | 2023-06-09 | 中国医学科学院药物研究所 | 苯并氮杂环类化合物及其制法和药物用途 |
| TW202120095A (zh) * | 2019-08-05 | 2021-06-01 | 美商美國禮來大藥廠 | 7,8-二氫-4H-吡唑并[4,3-c]氮呯-6-酮化合物 |
| CN112574189B (zh) | 2019-09-27 | 2024-05-31 | 海创药业股份有限公司 | 一种ep300/cbp抑制剂 |
| CA3156007A1 (en) | 2019-09-27 | 2021-04-01 | Disc Medicine, Inc. | METHODS OF TREATING MYELOFIBROSE AND ASSOCIATED CONDITIONS |
| US11242353B2 (en) | 2020-01-24 | 2022-02-08 | Trustees Of Boston University | Heterocyclic LSF inhibitors and their uses |
| US12486251B2 (en) | 2020-04-25 | 2025-12-02 | Pharmablock Sciences (Nanjing) , Inc. | CBP/EP300 inhibitor and use thereof |
| ES3075793T3 (en) | 2020-05-13 | 2026-08-07 | Disc Medicine Inc | Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis |
| AU2021273014A1 (en) | 2020-05-13 | 2022-11-17 | AbbVie Deutschland GmbH & Co. KG | Anti-hemojuvelin (HJV) antibodies for treating anemia of chronic disease |
| WO2022051388A2 (en) | 2020-09-01 | 2022-03-10 | Trustees Of Boston University | Quinolin-2(1h)-one inhibitors of late sv40 factor |
| EP4210683A4 (en) * | 2020-09-09 | 2024-10-09 | Aurigene Oncology Limited | Heterocyclic compounds as cbp/ep300 bromodomain inhibitors |
| US11801243B2 (en) | 2020-09-23 | 2023-10-31 | Forma Therapeutics, Inc. | Bromodomain inhibitors for androgen receptor-driven cancers |
| US11795168B2 (en) | 2020-09-23 | 2023-10-24 | Forma Therapeutics, Inc. | Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP) |
| KR20230080441A (ko) | 2020-10-02 | 2023-06-07 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 전사 활성화 단백질의 이미다조피페라진 억제제 |
| JP7777131B2 (ja) | 2020-10-02 | 2025-11-27 | ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム | 転写活性化タンパク質のイミダゾピペラジン阻害剤 |
| CN118459539B (zh) * | 2021-03-19 | 2026-01-06 | 生物治疗探索股份有限公司 | 用于调节训练免疫的化合物及其使用方法 |
| CN113087683B (zh) * | 2021-03-22 | 2022-04-22 | 华南理工大学 | 氮取代苯并噻唑啉酮类xor/urat1双重抑制剂及其制备方法与应用 |
| TW202409023A (zh) | 2022-07-14 | 2024-03-01 | 美商富曼西公司 | 除草苯并𠯤 |
| CN117843618A (zh) * | 2022-08-29 | 2024-04-09 | 北京沐华生物科技有限责任公司 | 一种ep300/cbp调节剂及其制备方法和用途 |
| CN122295330A (zh) * | 2023-08-30 | 2026-06-26 | 翁科皮亚治疗公司和Sk生命科学实验室 | 作为cbp/p300降解剂的化合物和组合物及其用途 |
| AU2024387082A1 (en) | 2023-11-21 | 2026-06-04 | Fmc Corporation | Substituted tetrahydroquinoline and tetrahydroquinoxaline herbicides |
| WO2026128761A1 (en) | 2024-12-11 | 2026-06-18 | Nexo Therapeutics, Inc. | Covalent p300 inhibitor compounds |
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-
2017
- 2017-05-24 WO PCT/US2017/034320 patent/WO2017205536A2/en not_active Ceased
- 2017-05-24 EP EP22152776.5A patent/EP4067347B1/en active Active
- 2017-05-24 MA MA045122A patent/MA45122A/fr unknown
- 2017-05-24 EP EP17728375.1A patent/EP3464270B1/en active Active
- 2017-05-24 CN CN201780045651.4A patent/CN109476641B/zh not_active Expired - Fee Related
- 2017-05-24 JP JP2018561543A patent/JP7160688B2/ja not_active Expired - Fee Related
- 2017-05-24 CN CN202210701205.7A patent/CN115028617A/zh active Pending
-
2018
- 2018-11-21 US US16/198,597 patent/US10696655B2/en active Active
-
2020
- 2020-05-28 US US16/886,541 patent/US11168070B2/en not_active Expired - Fee Related
-
2022
- 2022-10-13 JP JP2022164864A patent/JP2023002643A/ja active Pending
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