JP2018507191A5 - - Google Patents
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- JP2018507191A5 JP2018507191A5 JP2017539592A JP2017539592A JP2018507191A5 JP 2018507191 A5 JP2018507191 A5 JP 2018507191A5 JP 2017539592 A JP2017539592 A JP 2017539592A JP 2017539592 A JP2017539592 A JP 2017539592A JP 2018507191 A5 JP2018507191 A5 JP 2018507191A5
- Authority
- JP
- Japan
- Prior art keywords
- carbocyclyl
- alkyl
- group
- independently selected
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562109522P | 2015-01-29 | 2015-01-29 | |
| US62/109,522 | 2015-01-29 | ||
| PCT/US2016/015450 WO2016123391A1 (en) | 2015-01-29 | 2016-01-28 | Therapeutic compounds and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018507191A JP2018507191A (ja) | 2018-03-15 |
| JP2018507191A5 true JP2018507191A5 (enExample) | 2019-03-07 |
| JP6709792B2 JP6709792B2 (ja) | 2020-06-17 |
Family
ID=55361971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017539592A Expired - Fee Related JP6709792B2 (ja) | 2015-01-29 | 2016-01-28 | 治療用化合物およびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10202378B2 (enExample) |
| EP (1) | EP3250571B1 (enExample) |
| JP (1) | JP6709792B2 (enExample) |
| CN (1) | CN107531692B (enExample) |
| WO (1) | WO2016123391A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA40943A (fr) | 2014-11-10 | 2017-09-19 | Constellation Pharmaceuticals Inc | Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines |
| WO2016077375A1 (en) | 2014-11-10 | 2016-05-19 | Genentech, Inc. | Bromodomain inhibitors and uses thereof |
| MA40940A (fr) | 2014-11-10 | 2017-09-19 | Constellation Pharmaceuticals Inc | Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines |
| CN109641894B (zh) * | 2016-08-24 | 2022-09-09 | 豪夫迈·罗氏有限公司 | 2-氮杂双环[3.1.0]己烷-3-酮衍生物及使用方法 |
| JP7138093B2 (ja) * | 2016-08-24 | 2022-09-15 | エフ．ホフマン－ラ ロシュ アーゲー | ２－アザビシクロ［３．１．０］ヘキサン－３－オン誘導体及び使用方法 |
| US11171132B2 (en) * | 2019-10-03 | 2021-11-09 | Globalfoundries U.S. Inc. | Bi-directional breakdown silicon controlled rectifiers |
| CN112625036A (zh) * | 2019-10-08 | 2021-04-09 | 上海海和药物研究开发股份有限公司 | 一类具有brd4抑制活性的化合物、其制备方法及用途 |
| CN114591338B (zh) * | 2022-03-31 | 2023-05-09 | 苏州欧康维视生物科技有限公司 | 一种Syk和VEGFR2双靶点抑制剂的制备方法及其用途 |
| CN120136817A (zh) * | 2025-05-16 | 2025-06-13 | 安徽泽升科技股份有限公司 | 一种氧杂环丁烷-3-甲醇和氧杂环丁烷-3-甲醛的制备方法 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| UA119870C2 (uk) | 2014-04-23 | 2019-08-27 | Інсайт Корпорейшн | 1H-ПІРОЛО[2,3-c]ПІРИДИН-7(6H)-ОНИ ТА ПІРАЗОЛО[3,4-c]ПІРИДИН-7(6H)-ОНИ ЯК ІНГІБІТОРИ БІЛКІВ BET |
| WO2016077375A1 (en) | 2014-11-10 | 2016-05-19 | Genentech, Inc. | Bromodomain inhibitors and uses thereof |
| MA40940A (fr) | 2014-11-10 | 2017-09-19 | Constellation Pharmaceuticals Inc | Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines |
| MA40943A (fr) | 2014-11-10 | 2017-09-19 | Constellation Pharmaceuticals Inc | Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines |
| CN107531690B (zh) | 2014-11-27 | 2020-11-06 | 基因泰克公司 | 用作CBP和/或EP300抑制剂的4,5,6,7-四氢-1H-吡唑并[4,3-c]吡啶-3-胺化合物 |
| EP3247353A4 (en) | 2015-01-23 | 2018-07-04 | Confluence Life Sciences, Inc. | Heterocyclic itk inhibitors for treating inflammation and cancer |
-
2016
- 2016-01-28 CN CN201680019098.2A patent/CN107531692B/zh not_active Expired - Fee Related
- 2016-01-28 JP JP2017539592A patent/JP6709792B2/ja not_active Expired - Fee Related
- 2016-01-28 WO PCT/US2016/015450 patent/WO2016123391A1/en not_active Ceased
- 2016-01-28 EP EP16704984.0A patent/EP3250571B1/en active Active
-
2017
- 2017-07-24 US US15/658,213 patent/US10202378B2/en active Active
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