JP2019514945A5 - - Google Patents

Download PDF

Info

Publication number
JP2019514945A5
JP2019514945A5 JP2018557398A JP2018557398A JP2019514945A5 JP 2019514945 A5 JP2019514945 A5 JP 2019514945A5 JP 2018557398 A JP2018557398 A JP 2018557398A JP 2018557398 A JP2018557398 A JP 2018557398A JP 2019514945 A5 JP2019514945 A5 JP 2019514945A5
Authority
JP
Japan
Prior art keywords
formula
compound
general formula
acute
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018557398A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019514945A (ja
JP6932140B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2017/060356 external-priority patent/WO2017191102A1/en
Publication of JP2019514945A publication Critical patent/JP2019514945A/ja
Publication of JP2019514945A5 publication Critical patent/JP2019514945A5/ja
Application granted granted Critical
Publication of JP6932140B2 publication Critical patent/JP6932140B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018557398A 2016-05-03 2017-05-02 アミド置換ピリジニルトリアゾール誘導体およびその用途 Expired - Fee Related JP6932140B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16168165 2016-05-03
EP16168165.5 2016-05-03
PCT/EP2017/060356 WO2017191102A1 (en) 2016-05-03 2017-05-02 Amide-substituted pyridinyltriazole derivatives and uses thereof

Publications (3)

Publication Number Publication Date
JP2019514945A JP2019514945A (ja) 2019-06-06
JP2019514945A5 true JP2019514945A5 (https=) 2020-06-11
JP6932140B2 JP6932140B2 (ja) 2021-09-08

Family

ID=55910850

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018557398A Expired - Fee Related JP6932140B2 (ja) 2016-05-03 2017-05-02 アミド置換ピリジニルトリアゾール誘導体およびその用途

Country Status (42)

Country Link
US (4) US9988367B2 (https=)
EP (1) EP3452463B1 (https=)
JP (1) JP6932140B2 (https=)
KR (1) KR20190003655A (https=)
CN (2) CN113121504A (https=)
AR (1) AR108262A1 (https=)
AU (1) AU2017259870B2 (https=)
BR (1) BR112018072542A2 (https=)
CA (1) CA3022749A1 (https=)
CL (1) CL2018003105A1 (https=)
CO (1) CO2018011933A2 (https=)
CR (1) CR20180522A (https=)
CU (1) CU24567B1 (https=)
CY (1) CY1124084T1 (https=)
DK (1) DK3452463T3 (https=)
DO (1) DOP2018000240A (https=)
EA (1) EA035596B1 (https=)
EC (1) ECSP18081881A (https=)
ES (1) ES2866109T3 (https=)
GE (2) GEAP202014945A (https=)
HR (1) HRP20210648T1 (https=)
HU (1) HUE053908T2 (https=)
IL (1) IL262557B (https=)
JO (1) JOP20170105B1 (https=)
LT (1) LT3452463T (https=)
MA (1) MA44851B1 (https=)
MX (1) MX381787B (https=)
NI (1) NI201800115A (https=)
PE (1) PE20190116A1 (https=)
PH (1) PH12018502268A1 (https=)
PL (1) PL3452463T3 (https=)
PT (1) PT3452463T (https=)
RS (1) RS61771B1 (https=)
SG (1) SG11201809752VA (https=)
SI (1) SI3452463T1 (https=)
SV (1) SV2018005771A (https=)
TN (1) TN2018000368A1 (https=)
TW (1) TWI772295B (https=)
UA (1) UA123791C2 (https=)
UY (1) UY37220A (https=)
WO (1) WO2017191102A1 (https=)
ZA (1) ZA201808131B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6911052B2 (ja) * 2016-05-03 2021-07-28 バイエル ファーマ アクチエンゲゼルシャフト オキソアルキル置換フェニルトリアゾール誘導体およびその使用
JOP20170103A1 (ar) * 2016-05-03 2017-11-03 Bayer Pharma AG عملية لتحضير مشتقات 1-فنيل-1، 2، 4-تريازول مستبدلة بـ 5-هيدروكسي ألكيل
CN114984003B (zh) 2016-05-03 2024-08-27 拜耳制药股份公司 芳族磺酰胺衍生物
US9988367B2 (en) * 2016-05-03 2018-06-05 Bayer Pharma Aktiengesellschaft Amide-substituted pyridinyltriazole derivatives and uses thereof
US10893352B2 (en) * 2016-08-24 2021-01-12 Matthew Hawkes Programmable interactive stereo headphones with tap functionality and network connectivity
US10954197B2 (en) * 2017-03-08 2021-03-23 Yogee's Bioinnovations Private Limited Cathepsin-D and angiogenesis inhibitors and compositions thereof for treating breast cancer
US11026625B2 (en) 2017-08-08 2021-06-08 Fresenius Medical Care Holdings, Inc. Systems and methods for treating and estimating progression of chronic kidney disease
US11149023B2 (en) 2017-10-24 2021-10-19 Bayer Pharma Aktiengesellschaft Substituted triazole derivatives and uses thereof
CR20200176A (es) 2017-10-24 2020-07-24 Bayer Pharma AG Profármacos de derivados de triazol sustituido y sus usos
WO2019081291A1 (en) 2017-10-24 2019-05-02 Bayer Aktiengesellschaft PRODRUGS OF SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF
CA3079770A1 (en) 2017-10-24 2019-05-02 Bayer Pharma Aktiengesellschaft Amine substituted triazole derivatives and uses thereof
WO2019081306A1 (en) 2017-10-24 2019-05-02 Bayer Pharma Aktiengesellschaft SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF
EP3700900A1 (en) 2017-10-24 2020-09-02 Bayer Aktiengesellschaft Substituted triazole derivatives and uses thereof
US20210253557A1 (en) 2017-10-24 2021-08-19 Bayer Pharma Aktiengesellschaft Substituted triazole derivatives and uses thereof
HU231206B1 (hu) 2017-12-15 2021-10-28 Richter Gedeon Nyrt. Triazolobenzazepinek
TW201938171A (zh) 2017-12-15 2019-10-01 匈牙利商羅特格登公司 作為血管升壓素Ｖ１ａ受體拮抗劑之三環化合物
US11020351B2 (en) * 2018-03-26 2021-06-01 Hetero Labs Limited Stable bilayer tablet compositions
WO2019199273A1 (en) * 2018-04-10 2019-10-17 Hewlett-Packard Development Company, L.P. Preheat dyed build materials with preheating sources
KR20260018202A (ko) * 2019-12-24 2026-02-06 도쿄엘렉트론가부시키가이샤 성막 방법 및 성막 시스템
US12569481B2 (en) 2020-06-12 2026-03-10 Vanderbilt University Methods of treatment for gastrointestinal motility disorders
WO2021259852A1 (en) 2020-06-25 2021-12-30 Bayer Aktiengesellschaft Process for preparing 5-(alkoxycarbonyl)-and 5-(carboxamide)-1-aryl-1,2,4-triazole derivatives
WO2022112213A1 (en) 2020-11-30 2022-06-02 Bayer Aktiengesellschaft Crystalline forms of 3-[[3-(4-chlorophenyl)-5-oxo-4-((2s)-3,3,3-trifluoro- 2-hydroxypropyl)-4,5-dihydro-1h-1,2,4-triazol-1-yl]methyl]-1-[3- (trifluoromethyl)pyridin-2-yl]-1h-1,2,4-triazole-5-carboxamide
EP4626419A1 (en) * 2022-11-29 2025-10-08 The United States Government as represented by the Department of Veterans Affairs Eif4a1 inhibitors with antitumor activity
WO2026035773A1 (en) * 2024-08-06 2026-02-12 Retex Pharmaceuticals, Inc. Vasopressin receptor 2 modulators and methods of use thereof

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3042466A1 (de) 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US5468448A (en) 1989-12-28 1995-11-21 Ciba-Geigy Corporation Peroxide disinfection method and devices therefor
DE4107857A1 (de) 1991-03-12 1992-09-17 Thomae Gmbh Dr K Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
JP3290657B2 (ja) 1991-05-01 2002-06-10 メルク エンド カムパニー インコーポレーテッド アンギオテンシンｉｉ拮抗剤として活性な酸性アラルキルトリアゾール誘導体
WO1993017681A1 (en) 1992-03-02 1993-09-16 Abbott Laboratories Angiotensin ii receptor antagonists
SK94393A3 (en) 1992-09-11 1994-08-10 Thomae Gmbh Dr K Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those
GB9311920D0 (en) 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
US6844005B2 (en) 2002-02-25 2005-01-18 Trutek Corp Electrostatically charged nasal application product with increased strength
FR2708608B1 (fr) 1993-07-30 1995-10-27 Sanofi Sa Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
US20010020100A1 (en) 1994-06-14 2001-09-06 G.D. Searle & Co. N-substituted-1, 2, 4-triazolone compounds for treatment of cardiovascular disorders
TR200001752T2 (tr) 1997-12-17 2000-12-21 Merck & Co., Inc. Entegrin reseptör antagonistleri
DE19816882A1 (de) 1998-04-17 1999-10-21 Boehringer Ingelheim Pharma Triazolone mit neuroprotektiver Wirkung
CN1177835C (zh) 1998-07-24 2004-12-01 拜尔公司 取代的苯甲酰基环己二酮类化合物
DE19834047A1 (de) 1998-07-29 2000-02-03 Bayer Ag Substituierte Pyrazolderivate
DE19834044A1 (de) 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
DE19914140A1 (de) 1999-03-27 2000-09-28 Bayer Ag Substituierte Benzoylpyrazole
AP2005003199A0 (en) 1999-04-01 2005-03-31 Pfizer Prod Inc Aminopyrimidines as sorbitol dehydrogenase inhibitors
DE19920791A1 (de) 1999-05-06 2000-11-09 Bayer Ag Substituierte Benzoylisoxazole
DE19921424A1 (de) 1999-05-08 2000-11-09 Bayer Ag Substituierte Benzoylketone
DE19929348A1 (de) 1999-06-26 2000-12-28 Bayer Ag Verfahren zur Herstellung von 2-Heterocyclylmethyl-benzoesäurederivaten
US6531142B1 (en) 1999-08-18 2003-03-11 The Procter & Gamble Company Stable, electrostatically sprayable topical compositions
DE19943636A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE19943639A1 (de) 1999-09-13 2001-03-15 Bayer Ag Dicarbonsäurederivate mit neuartigen pharmazeutischen Eigenschaften
DE19943634A1 (de) 1999-09-13 2001-04-12 Bayer Ag Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften
DE19943635A1 (de) 1999-09-13 2001-03-15 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
AR027575A1 (es) 2000-03-06 2003-04-02 Bayer Ag Benzoilciclohexenonas substituidas
US7080644B2 (en) 2000-06-28 2006-07-25 Microdose Technologies, Inc. Packaging and delivery of pharmaceuticals and drugs
AR031176A1 (es) 2000-11-22 2003-09-10 Bayer Ag Nuevos derivados de pirazolpiridina sustituidos con piridina
WO2002066447A1 (en) 2001-02-21 2002-08-29 Ono Pharmaceutical Co., Ltd. 4h-1,2,4-triazole-3(2h)-thione deratives as sphingomyelinase inhibitors
DE10110749A1 (de) 2001-03-07 2002-09-12 Bayer Ag Substituierte Aminodicarbonsäurederivate
DE10110750A1 (de) 2001-03-07 2002-09-12 Bayer Ag Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
US20040071757A1 (en) 2001-11-20 2004-04-15 David Rolf Inhalation antiviral patch
DE10220570A1 (de) 2002-05-08 2003-11-20 Bayer Ag Carbamat-substituierte Pyrazolopyridine
AU2004221891B2 (en) 2003-03-14 2009-11-19 Merck Sharp & Dohme Corp. Monocyclic anilide spirohydantoin CGRP receptor antagonists
KR20060066141A (ko) 2003-06-27 2006-06-15 버글린 코퍼레이션 오브 워싱턴 사과 및 연한 코아를 가지거나 피트를 가진 다른 과일들을작은 응력을 가지고 정확하게 코아제거하고슬라이스절단하기 위한 기계
EA010132B1 (ru) * 2003-12-22 2008-06-30 Пфайзер Инк. Производные триазола в качестве антагонистов вазопрессина
EP1723117A4 (en) 2004-03-08 2009-12-02 Wyeth Corp ION CHANNEL MODULATORS
BRPI0508522A (pt) 2004-03-08 2007-08-14 Wyeth Corp moduladores de canal de ìon
CA2563963A1 (en) 2004-04-28 2005-11-10 Pfizer Inc. 3-heterocyclyl-4-phenyl-triazole derivatives as inhibitors of the vasopressin v1a receptor
JP2008524246A (ja) 2004-12-16 2008-07-10 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
WO2006117657A1 (en) 2005-05-03 2006-11-09 Ranbaxy Laboratories Limited Triazolone derivatives as anti-inflammatory agents
DE102006024024A1 (de) 2006-05-23 2007-11-29 Bayer Healthcare Aktiengesellschaft Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung
DE102008060967A1 (de) 2008-12-06 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Substituierte Phenylsulfonyltriazolone und ihre Verwendung
DE102009013642A1 (de) 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte Phenylalaninderivate und deren Verwendung
DE102010001064A1 (de) 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
DE102009028929A1 (de) 2009-08-27 2011-07-07 Bayer Schering Pharma Aktiengesellschaft, 13353 Heterocyclisch-substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
EA023221B1 (ru) * 2010-02-27 2016-05-31 Байер Интеллектуэль Проперти Гмбх СВЯЗАННЫЕ БИС-АРИЛЬНЫЕ АРИЛ-ТРИАЗОЛОНЫ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ, ИХ ПРИМЕНЕНИЕ, ЛЕКАРСТВЕННОЕ СРЕДСТВО НА ИХ ОСНОВЕ И ДВОЙНОЙ АНТАГОНИСТ V1a/V2-РЕЦЕПТОРОВ
DE102010021637A1 (de) 2010-05-26 2011-12-01 Bayer Schering Pharma Aktiengesellschaft Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung
PE20130779A1 (es) 2010-07-09 2013-06-21 Bayer Ip Gmbh Pirimidinas y triazinas condensadas y su uso
DE102010040187A1 (de) 2010-09-02 2012-03-08 Bayer Schering Pharma Aktiengesellschaft Substituierte N-Phenethyl-triazolonacetamide und ihre Verwendung
DE102010040233A1 (de) 2010-09-03 2012-03-08 Bayer Schering Pharma Aktiengesellschaft Bicyclische Aza-Heterocyclen und ihre Verwendung
MX2013003633A (es) * 2010-10-01 2013-04-24 Taisho Pharmaceutical Co Ltd Derivado de 1, 2, 4-triazolona.
DE102010043379A1 (de) 2010-11-04 2012-05-10 Bayer Schering Pharma Aktiengesellschaft Substituierte 6-Fluor-1H-Pyrazolo[4,3-b]pyridine und ihre Verwendung
WO2012112363A1 (en) 2011-02-14 2012-08-23 Merck Sharp & Dohme Corp. Cathepsin cysteine protease inhibitors
WO2013138860A1 (en) 2012-03-22 2013-09-26 Biota Europe Limited Antibacterial compounds
UA121558C2 (uk) 2014-11-03 2020-06-25 Баєр Фарма Актіенгезеллшафт Гідроксіалкілзаміщені фенілтриазольні похідні та їх застосування
US9988367B2 (en) * 2016-05-03 2018-06-05 Bayer Pharma Aktiengesellschaft Amide-substituted pyridinyltriazole derivatives and uses thereof
JOP20170103A1 (ar) * 2016-05-03 2017-11-03 Bayer Pharma AG عملية لتحضير مشتقات 1-فنيل-1، 2، 4-تريازول مستبدلة بـ 5-هيدروكسي ألكيل
JP6911052B2 (ja) * 2016-05-03 2021-07-28 バイエル ファーマ アクチエンゲゼルシャフト オキソアルキル置換フェニルトリアゾール誘導体およびその使用

Similar Documents

Publication Publication Date Title
JP2019514945A5 (https=)
HRP20210648T1 (hr) Amid-supstituirani derivati piridiniltriazola i njihova uporaba
TW544453B (en) Novel guanidine mimics as factor Xa inhibitors
EP1651615B1 (en) Pyridazinyl- piperazines and their use as histamine h3 receptor ligands
DE3750687T2 (de) Angiotensin II-Rezeptorblockierende Imidazole.
JP4463317B2 (ja) 置換イミダゾールおよび殺虫剤としてのその使用
SA517381429B1 (ar) مشتقات فينيل تريازول مستبدلة مع هيدروكسي ألكيل واستخداماتها
AU2014272776C1 (en) Pyrazolopyrrolidine derivatives and their use in the treatment of disease
AU2010200135A1 (en) Novel aryl-and heteroarylpiperazines
TWI772309B (zh) 化合物及其於降低尿酸位準之用途(二)
JP2006504658A5 (https=)
CA2262252C (en) Method of treating heart failure
KR20130004316A (ko) 비스아릴-결합된 아릴트리아졸론 및 그의 용도
JP2010507602A5 (https=)
JP2002080453A (ja) 選択的シクロオキシゲナーゼ−２阻害物質となる置換ピリジン
CN106304835A (zh) sGC刺激剂
JP2002520274A (ja) バルサルタンとカルシウムチャンネルブロッカーの抗高血圧組合わせ
JP2003513961A (ja) シクロオキシゲナーゼ−２の阻害剤である５−アリール−１ｈ−１，２，４−トリアゾール化合物とそれを含む医薬品組成物
JP5643213B2 (ja) 肥大性心筋症治療用のホスホジエステラーゼタイプＩＩＩ（ＰＤＥＩＩＩ）インヒビターまたはＣａ２＋感作剤
CZ280018B6 (cs) 4-alkylimidazolové deriváty
JP2014532726A5 (https=)
WO2017013010A1 (de) Stimulatoren und/oder aktivatoren der löslichen guanylatzyklase (sgc) in kombination mit einem inhibitor der neutralen endopeptidase (nep inhibitor) und/oder einem angiotensin aii-antagonisten und ihre verwendung
JP2012503005A5 (https=)
WO2012028644A1 (de) Substituierte n-phenethyl-triazolonacetamide und ihre verwendung
US20130225638A1 (en) Imidazole derivatives and preparation method and use thereof