JP2019514426A5 - - Google Patents
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- Publication number
- JP2019514426A5 JP2019514426A5 JP2019508165A JP2019508165A JP2019514426A5 JP 2019514426 A5 JP2019514426 A5 JP 2019514426A5 JP 2019508165 A JP2019508165 A JP 2019508165A JP 2019508165 A JP2019508165 A JP 2019508165A JP 2019514426 A5 JP2019514426 A5 JP 2019514426A5
- Authority
- JP
- Japan
- Prior art keywords
- oligomeric compound
- antisense oligomeric
- seq
- antisense
- cpp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022000125A JP2022046725A (ja) | 2016-04-29 | 2022-01-04 | ヒトｌｍｎａを標的にするオリゴヌクレオチド類縁体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662330027P | 2016-04-29 | 2016-04-29 | |
| US62/330,027 | 2016-04-29 | ||
| PCT/US2017/030174 WO2017190041A1 (en) | 2016-04-29 | 2017-04-28 | Oligonucleotide analogues targeting human lmna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022000125A Division JP2022046725A (ja) | 2016-04-29 | 2022-01-04 | ヒトｌｍｎａを標的にするオリゴヌクレオチド類縁体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019514426A JP2019514426A (ja) | 2019-06-06 |
| JP2019514426A5 true JP2019514426A5 (enExample) | 2020-05-21 |
| JP7042255B2 JP7042255B2 (ja) | 2022-03-25 |
Family
ID=59285320
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019508165A Active JP7042255B2 (ja) | 2016-04-29 | 2017-04-28 | ヒトｌｍｎａを標的にするオリゴヌクレオチド類縁体 |
| JP2022000125A Pending JP2022046725A (ja) | 2016-04-29 | 2022-01-04 | ヒトｌｍｎａを標的にするオリゴヌクレオチド類縁体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022000125A Pending JP2022046725A (ja) | 2016-04-29 | 2022-01-04 | ヒトｌｍｎａを標的にするオリゴヌクレオチド類縁体 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10822608B2 (enExample) |
| EP (1) | EP3449000A1 (enExample) |
| JP (2) | JP7042255B2 (enExample) |
| KR (1) | KR102329187B1 (enExample) |
| CN (1) | CN109477109B (enExample) |
| AU (2) | AU2017258642B2 (enExample) |
| CA (1) | CA3022303A1 (enExample) |
| CO (1) | CO2018012873A2 (enExample) |
| EA (1) | EA201892467A1 (enExample) |
| MA (1) | MA45616A (enExample) |
| MX (1) | MX2018013157A (enExample) |
| NZ (1) | NZ747685A (enExample) |
| SG (1) | SG11201809468XA (enExample) |
| WO (1) | WO2017190041A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9340800B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | Extended DNA-sensing GRNAS |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| EP4434589A3 (en) | 2015-10-23 | 2025-05-14 | President and Fellows of Harvard College | Evolved cas9 proteins for gene editing |
| NZ747685A (en) * | 2016-04-29 | 2023-05-26 | Sarepta Therapeutics Inc | Oligonucleotide analogues targeting human lmna |
| JP7231935B2 (ja) | 2016-08-03 | 2023-03-08 | プレジデント アンド フェローズ オブ ハーバード カレッジ | アデノシン核酸塩基編集因子およびそれらの使用 |
| US11661590B2 (en) | 2016-08-09 | 2023-05-30 | President And Fellows Of Harvard College | Programmable CAS9-recombinase fusion proteins and uses thereof |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| AU2017342543B2 (en) | 2016-10-14 | 2024-06-27 | President And Fellows Of Harvard College | AAV delivery of nucleobase editors |
| HRP20240705T1 (hr) | 2016-12-19 | 2024-08-30 | Sarepta Therapeutics, Inc. | Oligomerni konjugati koji preskaču egzon za mišićnu distrofiju |
| WO2018119359A1 (en) | 2016-12-23 | 2018-06-28 | President And Fellows Of Harvard College | Editing of ccr5 receptor gene to protect against hiv infection |
| CN110662556A (zh) | 2017-03-09 | 2020-01-07 | 哈佛大学的校长及成员们 | 癌症疫苗 |
| US11898179B2 (en) | 2017-03-09 | 2024-02-13 | President And Fellows Of Harvard College | Suppression of pain by gene editing |
| JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
| WO2018176009A1 (en) | 2017-03-23 | 2018-09-27 | President And Fellows Of Harvard College | Nucleobase editors comprising nucleic acid programmable dna binding proteins |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| US11732274B2 (en) | 2017-07-28 | 2023-08-22 | President And Fellows Of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE) |
| WO2019139645A2 (en) | 2017-08-30 | 2019-07-18 | President And Fellows Of Harvard College | High efficiency base editors comprising gam |
| KR20200121782A (ko) | 2017-10-16 | 2020-10-26 | 더 브로드 인스티튜트, 인코퍼레이티드 | 아데노신 염기 편집제의 용도 |
| US12406749B2 (en) | 2017-12-15 | 2025-09-02 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| US12157760B2 (en) | 2018-05-23 | 2024-12-03 | The Broad Institute, Inc. | Base editors and uses thereof |
| US12522807B2 (en) | 2018-07-09 | 2026-01-13 | The Broad Institute, Inc. | RNA programmable epigenetic RNA modifiers and uses thereof |
| TW202449155A (zh) * | 2018-07-27 | 2024-12-16 | 美商薩羅塔治療公司 | 用於肌肉萎縮症之外顯子跳躍寡聚物 |
| WO2020051360A1 (en) * | 2018-09-05 | 2020-03-12 | The Broad Institute, Inc. | Base editing for treating hutchinson-gilford progeria syndrome |
| WO2020092453A1 (en) | 2018-10-29 | 2020-05-07 | The Broad Institute, Inc. | Nucleobase editors comprising geocas9 and uses thereof |
| WO2020154500A1 (en) | 2019-01-23 | 2020-07-30 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| MX2021011426A (es) | 2019-03-19 | 2022-03-11 | Broad Inst Inc | Metodos y composiciones para editar secuencias de nucleótidos. |
| WO2020214842A1 (en) | 2019-04-17 | 2020-10-22 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| US12435330B2 (en) | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
| WO2021226558A1 (en) | 2020-05-08 | 2021-11-11 | The Broad Institute, Inc. | Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence |
| WO2022098014A1 (ko) * | 2020-11-03 | 2022-05-12 | 한국생명공학연구원 | 유전자 교정을 이용한 조로증 및 자연노화의 예방 또는 치료용 조성물 |
| JP2025537104A (ja) * | 2022-11-02 | 2025-11-14 | サレプタ セラピューティクス， インコーポレイテッド | アンチセンスオリゴマーコンジュゲートの製剤化 |
| CN119101680A (zh) * | 2023-06-09 | 2024-12-10 | 良渚实验室 | 多核苷酸、药物组合物及其用途 |
| WO2025262186A2 (en) * | 2024-06-20 | 2025-12-26 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Therapeutic oligonucleotides for treating diseases being associated with or caused by a missense, nonsense or in-frame indel mutation |
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| NZ747685A (en) * | 2016-04-29 | 2023-05-26 | Sarepta Therapeutics Inc | Oligonucleotide analogues targeting human lmna |
-
2017
- 2017-04-28 NZ NZ747685A patent/NZ747685A/en unknown
- 2017-04-28 EP EP17735676.3A patent/EP3449000A1/en active Pending
- 2017-04-28 KR KR1020187034615A patent/KR102329187B1/ko active Active
- 2017-04-28 JP JP2019508165A patent/JP7042255B2/ja active Active
- 2017-04-28 WO PCT/US2017/030174 patent/WO2017190041A1/en not_active Ceased
- 2017-04-28 US US16/096,524 patent/US10822608B2/en active Active
- 2017-04-28 SG SG11201809468XA patent/SG11201809468XA/en unknown
- 2017-04-28 EA EA201892467A patent/EA201892467A1/ru unknown
- 2017-04-28 MX MX2018013157A patent/MX2018013157A/es unknown
- 2017-04-28 CN CN201780040785.7A patent/CN109477109B/zh active Active
- 2017-04-28 CA CA3022303A patent/CA3022303A1/en active Pending
- 2017-04-28 AU AU2017258642A patent/AU2017258642B2/en active Active
- 2017-04-28 MA MA045616A patent/MA45616A/fr unknown
-
2018
- 2018-11-27 CO CONC2018/0012873A patent/CO2018012873A2/es unknown
-
2020
- 2020-09-17 US US17/024,100 patent/US11802283B2/en active Active
-
2022
- 2022-01-04 JP JP2022000125A patent/JP2022046725A/ja active Pending
-
2023
- 2023-11-30 AU AU2023274161A patent/AU2023274161A1/en active Pending
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