MX2009010965A - Péptidos de tem8 y vacunas que los contienen. - Google Patents

Péptidos de tem8 y vacunas que los contienen.

Info

Publication number
MX2009010965A
MX2009010965A MX2009010965A MX2009010965A MX2009010965A MX 2009010965 A MX2009010965 A MX 2009010965A MX 2009010965 A MX2009010965 A MX 2009010965A MX 2009010965 A MX2009010965 A MX 2009010965A MX 2009010965 A MX2009010965 A MX 2009010965A
Authority
MX
Mexico
Prior art keywords
peptides
amino acid
vaccines
present
same
Prior art date
Application number
MX2009010965A
Other languages
English (en)
Inventor
Takuya Tsunoda
Ryuji Osawa
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of MX2009010965A publication Critical patent/MX2009010965A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

De acuerdo con la presente invención, se demostró que los péptidos que contienen la secuencia de aminoácidos de SEQ ID NO: 3, 4, 9, 23, 25, 30, 60, 63 o 68 tienen inducibilidad de linfocitos T citotóxicos (CTL). Por lo tanto, la presente invención proporciona un péptido que tiene la secuencia de aminoácidos seleccionada del grupo de SEQ ID NO: 3, 4, 9, 23, 25, 30, 60, 63 y 68. El péptido puede incluir una, dos, o varias sustituciones o adiciones de aminoácidos siempre y cuando se conserve la inducibilidad de CTL. Adicionalmente, la presente invención proporciona agentes farmacéuticos para el tratamiento y/o profilaxis de tumores, y/o para la prevención de su recurrencia postoperatoria, los cuales contienen cualquiera de estos péptidos. Los agentes farmacéuticos de esta invención incluyen vacunas.
MX2009010965A 2007-04-11 2008-04-10 Péptidos de tem8 y vacunas que los contienen. MX2009010965A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91119407P 2007-04-11 2007-04-11
PCT/JP2008/000932 WO2008126413A1 (en) 2007-04-11 2008-04-10 Tem8 peptides and vaccines comprising the same

Publications (1)

Publication Number Publication Date
MX2009010965A true MX2009010965A (es) 2009-12-01

Family

ID=39863572

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009010965A MX2009010965A (es) 2007-04-11 2008-04-10 Péptidos de tem8 y vacunas que los contienen.

Country Status (13)

Country Link
US (1) US8367799B2 (es)
EP (2) EP2155872A4 (es)
JP (1) JP5320544B2 (es)
KR (1) KR20100016355A (es)
CN (2) CN101711280B (es)
BR (1) BRPI0811021A2 (es)
CA (1) CA2683454A1 (es)
HK (1) HK1175197A1 (es)
IL (2) IL201386A0 (es)
MX (1) MX2009010965A (es)
RU (2) RU2498993C2 (es)
TW (2) TW201425333A (es)
WO (1) WO2008126413A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI500932B (zh) * 2008-12-05 2015-09-21 Oncotherapy Science Inc Ｗｄｒｐｕｈ抗原決定位胜肽以及含此胜肽之疫苗
US8574902B2 (en) * 2009-03-05 2013-11-05 Macrocure Ltd. Activated leukocyte composition and uses for wound healing
TW201136604A (en) 2009-12-14 2011-11-01 Oncotherapy Science Inc TMEM22 peptides and vaccines including the same
BR112012022641A2 (pt) 2010-03-11 2017-02-14 Oncotherapy Science Inc peptídeos hjurp e vacinas que incluem os mesmos
JP2013523084A (ja) * 2010-04-09 2013-06-17 オンコセラピー・サイエンス株式会社 Ｃｄｃａ５ペプチドおよびそれを含むワクチン
US8557777B2 (en) * 2010-07-09 2013-10-15 The Board Of Trustees Of The University Of Illinois Methods for treating cancer using prostate specific antigen and tumor endothelial marker peptides
AU2011300430C1 (en) 2010-09-09 2014-07-17 Macrocure, Ltd. Activated leukocyte conditioned supernatant and uses for wound healing
NZ611361A (en) * 2010-12-02 2014-10-31 Oncotherapy Science Inc Tomm34 peptides and vaccines including the same
KR102015648B1 (ko) * 2011-08-12 2019-08-28 온코세라피 사이언스 가부시키가이샤 Ｍｐｈｏｓｐｈ１ 펩티드 및 이를 포함한 백신
CA2852633C (en) * 2011-10-28 2021-08-03 Oncotherapy Science, Inc. Topk peptides and vaccines including the same
AU2013356143A1 (en) * 2012-12-04 2015-06-04 Oncotherapy Science, Inc. SEMA5B peptides and vaccines containing the same
TW201636358A (zh) * 2014-12-09 2016-10-16 腫瘤療法 科學股份有限公司 對於ｔｈ１細胞之ｇｐｃ３抗原決定位胜肽及含此之疫苗
CN106084026B (zh) * 2016-06-19 2019-10-25 中国人民解放军军事医学科学院生物工程研究所 肿瘤血管内皮细胞标志物8突变体、其融合蛋白及应用
RU2706554C1 (ru) * 2018-12-13 2019-11-19 Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ Способ создания противоинфекционной иммунологической защиты к Salmonella typhimurium и Listeria monocytogenes с помощью трансгенеза Т-лимфоцитов

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US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5804566A (en) 1993-08-26 1998-09-08 The Regents Of The University Of California Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
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US5922687A (en) 1995-05-04 1999-07-13 Board Of Trustees Of The Leland Stanford Junior University Intracellular delivery of nucleic acids using pressure
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US5853719A (en) 1996-04-30 1998-12-29 Duke University Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
WO1998004720A1 (en) 1996-07-26 1998-02-05 Sloan-Kettering Institute For Cancer Research Method and reagents for genetic immunization
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US6426205B1 (en) * 1997-10-24 2002-07-30 Mount Sinai Hospital Corporation Methods and compositions for modulating ubiquitin dependent proteolysis
CA2331761A1 (en) 1998-06-25 1999-12-29 Sumitomo Pharmaceuticals Co., Ltd. Tumor antigen peptides originating in cyclophilin b
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AU2486300A (en) * 1998-12-30 2000-07-31 Millennium Pharmaceuticals, Inc. Secreted proteins and nucleic acids encoding them
WO2002010217A2 (en) * 2000-08-02 2002-02-07 The Johns Hopkins University Endothelial cell expression patterns
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ITRM20060337A1 (it) * 2006-06-27 2007-12-28 Biosoot Srl Gene tem8 (tumor endotelial marker 8) e sue forme di espressione ed usi diagnostici e terapeutici

Also Published As

Publication number Publication date
CN101711280B (zh) 2013-04-10
RU2498993C2 (ru) 2013-11-20
EP2155872A4 (en) 2010-04-28
CN101711280A (zh) 2010-05-19
AU2008238739A1 (en) 2008-10-23
EP2508601B1 (en) 2014-11-05
KR20100016355A (ko) 2010-02-12
JP5320544B2 (ja) 2013-10-23
US20120093843A1 (en) 2012-04-19
IL201386A0 (en) 2011-08-01
EP2508601A2 (en) 2012-10-10
EP2508601A3 (en) 2013-02-13
WO2008126413A1 (en) 2008-10-23
TWI434853B (zh) 2014-04-21
EP2155872A1 (en) 2010-02-24
IL220752A0 (en) 2012-08-30
CA2683454A1 (en) 2008-10-23
BRPI0811021A2 (pt) 2014-10-21
CN102786582A (zh) 2012-11-21
US8367799B2 (en) 2013-02-05
TW200906850A (en) 2009-02-16
CN102786582B (zh) 2014-06-11
RU2013131089A (ru) 2015-01-10
TW201425333A (zh) 2014-07-01
HK1175197A1 (en) 2013-06-28
RU2009141595A (ru) 2011-05-20
JP2010523471A (ja) 2010-07-15

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