JP2020536091A5 - - Google Patents
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- JP2020536091A5 JP2020536091A5 JP2020519054A JP2020519054A JP2020536091A5 JP 2020536091 A5 JP2020536091 A5 JP 2020536091A5 JP 2020519054 A JP2020519054 A JP 2020519054A JP 2020519054 A JP2020519054 A JP 2020519054A JP 2020536091 A5 JP2020536091 A5 JP 2020536091A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- hydrogen
- ring
- optionally substituted
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CCC(C)(C*(C(C)N)C(*)(*)OC(C)(CC)C(C)(C)C)C(*)* Chemical compound CCC(C)(C*(C(C)N)C(*)(*)OC(C)(CC)C(C)(C)C)C(*)* 0.000 description 4
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762567323P | 2017-10-03 | 2017-10-03 | |
| US62/567,323 | 2017-10-03 | ||
| PCT/US2018/053871 WO2019070643A1 (en) | 2017-10-03 | 2018-10-02 | IMMUNOMODULATORS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020536091A JP2020536091A (ja) | 2020-12-10 |
| JP2020536091A5 true JP2020536091A5 (enExample) | 2021-11-11 |
| JP7257393B2 JP7257393B2 (ja) | 2023-04-13 |
Family
ID=63998773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020519054A Active JP7257393B2 (ja) | 2017-10-03 | 2018-10-02 | 免疫調節剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11492375B2 (enExample) |
| EP (1) | EP3692053A1 (enExample) |
| JP (1) | JP7257393B2 (enExample) |
| KR (1) | KR20200058506A (enExample) |
| CN (1) | CN111051332B (enExample) |
| WO (1) | WO2019070643A1 (enExample) |
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| CN110997698B (zh) | 2017-06-23 | 2023-12-26 | 百时美施贵宝公司 | 充当pd-1拮抗剂的免疫调节剂 |
| US10919852B2 (en) | 2017-07-28 | 2021-02-16 | Chemocentryx, Inc. | Immunomodulator compounds |
| KR102670486B1 (ko) | 2017-08-08 | 2024-05-28 | 케모센트릭스, 인크. | 마크로사이클릭 면역조절제 |
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| PE20210642A1 (es) | 2018-07-13 | 2021-03-23 | Gilead Sciences Inc | Inhibidores de pd-1/pd-l1 |
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| BR112021022659A2 (pt) | 2019-05-15 | 2022-03-29 | Chemocentryx Inc | Compostos triarílicos para o tratamento de doenças pd-l1 |
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| US20220363760A1 (en) | 2019-05-30 | 2022-11-17 | Bristol-Myers Squibb Company | Multi-tumor gene signature for suitability to immuno-oncology therapy |
| WO2020243570A1 (en) | 2019-05-30 | 2020-12-03 | Bristol-Myers Squibb Company | Cell localization signature and combination therapy |
| KR102841588B1 (ko) | 2019-06-20 | 2025-08-01 | 케모센트릭스, 인크. | Pd-l1 질환의 치료를 위한 화합물 |
| KR102890201B1 (ko) | 2019-07-10 | 2025-11-24 | 케모센트릭스, 인크. | Pd-l1 억제제로서의 인단 |
| WO2021055994A1 (en) | 2019-09-22 | 2021-03-25 | Bristol-Myers Squibb Company | Quantitative spatial profiling for lag-3 antagonist therapy |
| AU2020368392B2 (en) | 2019-10-16 | 2026-01-08 | Chemocentryx, Inc. | Heteroaryl-biphenyl amines for the treatment of PD-L1 diseases |
| ES3068390T3 (en) | 2019-10-16 | 2026-05-29 | Chemocentryx Inc | Heteroaryl-biphenyl amides for the treatment of pd-l1 diseases |
| EP4054723A1 (en) | 2019-11-08 | 2022-09-14 | Bristol-Myers Squibb Company | Lag-3 antagonist therapy for melanoma |
| CN114929728A (zh) | 2020-01-06 | 2022-08-19 | 百时美施贵宝公司 | 免疫调节剂 |
| KR20220161407A (ko) | 2020-03-30 | 2022-12-06 | 브리스톨-마이어스 스큅 컴퍼니 | 면역조정제 |
| CN111961117B (zh) * | 2020-08-19 | 2022-03-11 | 中山大学 | 一种环肽化合物及其应用 |
| MX2023002332A (es) | 2020-08-28 | 2023-03-21 | Bristol Myers Squibb Co | Terapia con antagonistas del gen 3 de activacion de linfocitos (lag-3) para carcinoma hepatocelular. |
| IL300916A (en) | 2020-08-31 | 2023-04-01 | Bristol Myers Squibb Co | Cell localization signature and immunotherapy |
| CA3196496A1 (en) | 2020-10-23 | 2022-04-28 | Laurence David TOMS | Lag-3 antagonist therapy for lung cancer |
| WO2022120179A1 (en) | 2020-12-03 | 2022-06-09 | Bristol-Myers Squibb Company | Multi-tumor gene signatures and uses thereof |
| CN117858719A (zh) | 2021-03-29 | 2024-04-09 | 朱诺治疗学股份有限公司 | 使用检查点抑制剂疗法和car t细胞疗法的组合进行给药和治疗的方法 |
| WO2023077090A1 (en) | 2021-10-29 | 2023-05-04 | Bristol-Myers Squibb Company | Lag-3 antagonist therapy for hematological cancer |
| AU2023213937A1 (en) | 2022-01-26 | 2024-07-18 | Bristol-Myers Squibb Company | Combination therapy for hepatocellular carcinoma |
| JP7851417B2 (ja) | 2022-04-08 | 2026-04-24 | ブリストル－マイヤーズ スクイブ カンパニー | 三次リンパ組織様構造の機械学習識別、分類、及び定量化 |
| KR20250123912A (ko) | 2022-12-21 | 2025-08-18 | 브리스톨-마이어스 스큅 컴퍼니 | 폐암에 대한 병용 요법 |
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| WO2025245489A1 (en) | 2024-05-24 | 2025-11-27 | Bristol-Myers Squibb Company | Treatment of tumors in subjects having fgl-1 positive samples |
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| US10358463B2 (en) | 2016-04-05 | 2019-07-23 | Bristol-Myers Squibb Company | Immunomodulators |
| WO2017201111A1 (en) | 2016-05-19 | 2017-11-23 | Bristol-Myers Squibb Company | Pet-imaging immunomodulators |
| KR102526034B1 (ko) | 2016-11-07 | 2023-04-25 | 브리스톨-마이어스 스큅 컴퍼니 | 면역조정제 |
| CN110997698B (zh) | 2017-06-23 | 2023-12-26 | 百时美施贵宝公司 | 充当pd-1拮抗剂的免疫调节剂 |
-
2018
- 2018-10-02 EP EP18793327.0A patent/EP3692053A1/en active Pending
- 2018-10-02 US US16/753,666 patent/US11492375B2/en active Active
- 2018-10-02 JP JP2020519054A patent/JP7257393B2/ja active Active
- 2018-10-02 KR KR1020207012116A patent/KR20200058506A/ko active Pending
- 2018-10-02 WO PCT/US2018/053871 patent/WO2019070643A1/en not_active Ceased
- 2018-10-02 CN CN201880055279.XA patent/CN111051332B/zh active Active