JP2019512469A5 - - Google Patents

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JP2019512469A5
JP2019512469A5 JP2018545336A JP2018545336A JP2019512469A5 JP 2019512469 A5 JP2019512469 A5 JP 2019512469A5 JP 2018545336 A JP2018545336 A JP 2018545336A JP 2018545336 A JP2018545336 A JP 2018545336A JP 2019512469 A5 JP2019512469 A5 JP 2019512469A5
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pharmaceutical composition
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JP2019512469A (ja
JP6814814B2 (ja
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Priority claimed from PCT/EP2017/055885 external-priority patent/WO2017157873A1/en
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JP2018545336A 2016-03-17 2017-03-14 Taarのアゴニストとしての活性を有する5−エチル−4−メチル−ピラゾール−3−カルボキサミド誘導体 Active JP6814814B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16160790.8 2016-03-17
EP16160790 2016-03-17
PCT/EP2017/055885 WO2017157873A1 (en) 2016-03-17 2017-03-14 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar

Publications (3)

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JP2019512469A JP2019512469A (ja) 2019-05-16
JP2019512469A5 true JP2019512469A5 (cg-RX-API-DMAC7.html) 2020-12-24
JP6814814B2 JP6814814B2 (ja) 2021-01-20

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JP2018545336A Active JP6814814B2 (ja) 2016-03-17 2017-03-14 Taarのアゴニストとしての活性を有する5−エチル−4−メチル−ピラゾール−3−カルボキサミド誘導体

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US (2) US10508107B2 (cg-RX-API-DMAC7.html)
EP (2) EP3757102A1 (cg-RX-API-DMAC7.html)
JP (1) JP6814814B2 (cg-RX-API-DMAC7.html)
KR (2) KR102537050B1 (cg-RX-API-DMAC7.html)
CN (1) CN108713019B (cg-RX-API-DMAC7.html)
AR (1) AR107878A1 (cg-RX-API-DMAC7.html)
AU (1) AU2017234042B2 (cg-RX-API-DMAC7.html)
BR (1) BR112018015389B1 (cg-RX-API-DMAC7.html)
CA (1) CA3013696C (cg-RX-API-DMAC7.html)
CL (1) CL2018002583A1 (cg-RX-API-DMAC7.html)
CO (1) CO2018007515A2 (cg-RX-API-DMAC7.html)
CR (1) CR20180443A (cg-RX-API-DMAC7.html)
DK (1) DK3430010T3 (cg-RX-API-DMAC7.html)
ES (1) ES2819830T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20201405T1 (cg-RX-API-DMAC7.html)
HU (1) HUE050986T2 (cg-RX-API-DMAC7.html)
IL (1) IL260473B (cg-RX-API-DMAC7.html)
LT (1) LT3430010T (cg-RX-API-DMAC7.html)
MA (2) MA53755A (cg-RX-API-DMAC7.html)
MX (1) MX377836B (cg-RX-API-DMAC7.html)
MY (1) MY195528A (cg-RX-API-DMAC7.html)
PE (1) PE20181446A1 (cg-RX-API-DMAC7.html)
PH (1) PH12018501588A1 (cg-RX-API-DMAC7.html)
PL (1) PL3430010T3 (cg-RX-API-DMAC7.html)
PT (1) PT3430010T (cg-RX-API-DMAC7.html)
RS (1) RS60825B1 (cg-RX-API-DMAC7.html)
RU (1) RU2731095C2 (cg-RX-API-DMAC7.html)
SG (2) SG11201807516UA (cg-RX-API-DMAC7.html)
SI (1) SI3430010T1 (cg-RX-API-DMAC7.html)
TW (1) TWI634117B (cg-RX-API-DMAC7.html)
UA (1) UA122881C2 (cg-RX-API-DMAC7.html)
WO (1) WO2017157873A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201804943B (cg-RX-API-DMAC7.html)

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BR112022000181A2 (pt) 2019-07-11 2022-02-22 Hoffmann La Roche Processo para a preparação de derivados de pirazol substituídos
JP2023517729A (ja) 2020-03-19 2023-04-26 エフ. ホフマン-ラ ロシュ アーゲー Taar1アゴニストの塩形態および結晶形態
WO2023079128A1 (en) 2021-11-08 2023-05-11 F. Hoffmann-La Roche Ag Catalytic hydrogenation of aromatic nitro compounds
CN114288304A (zh) * 2021-12-31 2022-04-08 江苏海洋大学 一种抗精神分裂症组合物及其应用
AR129909A1 (es) 2022-07-15 2024-10-09 Hoffmann La Roche Cetorreductasa mutante con mayor actividad de cetorreductasa así como métodos y usos de esta
CN119654138A (zh) 2022-08-12 2025-03-18 豪夫迈·罗氏有限公司 包含5-乙基-4-甲基-n-[4-[(2s)吗啉-2-基]苯基]-1h-吡唑-3-甲酰胺的药物组合物
EP4568654A1 (en) * 2022-08-12 2025-06-18 F. Hoffmann-La Roche AG Use of co-processed excipients in continuous manufacturing of solid dosage forms
TW202440563A (zh) * 2022-11-28 2024-10-16 美商住友製藥美國公司 2-苯基嗎啉與2-苯基(硫代)嗎啉化合物及其用途
WO2024222860A1 (zh) * 2023-04-28 2024-10-31 江苏豪森药业集团有限公司 一种吗啉杂环类化合物的盐及其制备方法和应用
WO2024258900A2 (en) * 2023-06-13 2024-12-19 University Of Georgia Research Foundation, Inc. Plasmodium falciparum blood stage inhibitors

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