JP2019510606A5 - - Google Patents
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- JP2019510606A5 JP2019510606A5 JP2019502289A JP2019502289A JP2019510606A5 JP 2019510606 A5 JP2019510606 A5 JP 2019510606A5 JP 2019502289 A JP2019502289 A JP 2019502289A JP 2019502289 A JP2019502289 A JP 2019502289A JP 2019510606 A5 JP2019510606 A5 JP 2019510606A5
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- Prior art keywords
- frequency
- amplitude
- time interval
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- electric field
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- 230000005684 electric field Effects 0.000 claims 18
- 206010028980 Neoplasm Diseases 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 8
- 230000011278 mitosis Effects 0.000 claims 3
- 230000004899 motility Effects 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- MAEIEVLCKWDQJH-UHFFFAOYSA-N bumetanide Chemical compound CCCCNC1=CC(C(O)=O)=CC(S(N)(=O)=O)=C1OC1=CC=CC=C1 MAEIEVLCKWDQJH-UHFFFAOYSA-N 0.000 claims 1
- 229960004064 bumetanide Drugs 0.000 claims 1
- 230000009087 cell motility Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021095883A JP7171827B2 (ja) | 2016-04-04 | 2021-06-08 | 腫瘍治療電場(TTFields)を使用してがん細胞の運動性を低下させる |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662317985P | 2016-04-04 | 2016-04-04 | |
| US62/317,985 | 2016-04-04 | ||
| PCT/IB2017/051898 WO2017175116A1 (en) | 2016-04-04 | 2017-04-04 | Reducing motility of cancer cells using tumor treating fields (ttfields) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021095883A Division JP7171827B2 (ja) | 2016-04-04 | 2021-06-08 | 腫瘍治療電場(TTFields)を使用してがん細胞の運動性を低下させる |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019510606A JP2019510606A (ja) | 2019-04-18 |
| JP2019510606A5 true JP2019510606A5 (enExample) | 2020-05-07 |
| JP6896839B2 JP6896839B2 (ja) | 2021-06-30 |
Family
ID=58530601
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502289A Active JP6896839B2 (ja) | 2016-04-04 | 2017-04-04 | 腫瘍治療電場(TTFields)を使用してがん細胞の運動性を低下させる |
| JP2021095883A Active JP7171827B2 (ja) | 2016-04-04 | 2021-06-08 | 腫瘍治療電場(TTFields)を使用してがん細胞の運動性を低下させる |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021095883A Active JP7171827B2 (ja) | 2016-04-04 | 2021-06-08 | 腫瘍治療電場(TTFields)を使用してがん細胞の運動性を低下させる |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10821283B2 (enExample) |
| EP (3) | EP3439733B1 (enExample) |
| JP (2) | JP6896839B2 (enExample) |
| KR (1) | KR102430229B1 (enExample) |
| CN (2) | CN109475735B (enExample) |
| CA (1) | CA3019474A1 (enExample) |
| DK (1) | DK3439733T3 (enExample) |
| ES (1) | ES2779990T3 (enExample) |
| HU (1) | HUE048646T2 (enExample) |
| PL (1) | PL3439733T3 (enExample) |
| PT (1) | PT3439733T (enExample) |
| WO (1) | WO2017175116A1 (enExample) |
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| DK3474760T3 (da) | 2016-06-27 | 2023-03-20 | Galvanize Therapeutics Inc | Generator og et kateter med en elektrode til at behandle en lungepassage |
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| EP3710102A4 (en) * | 2017-11-17 | 2021-08-04 | AbbVie Inc. | METHOD OF TREATMENT OF GLIOBLASTOMA |
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| KR20250069692A (ko) * | 2018-08-23 | 2025-05-19 | 카스텐 하게만 | 뇌-혈액 장벽 투과성을 향상시키기 위한 교번 전기장의 이용 |
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| US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| CN112770806B (zh) * | 2018-09-07 | 2025-12-05 | 诺沃库勒有限责任公司 | 使用交变电场治疗自身免疫性疾病以减少t细胞的增殖 |
| CN118925056A (zh) | 2018-10-15 | 2024-11-12 | 诺沃库勒有限责任公司 | 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields) |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| EP3880299B1 (en) | 2018-11-13 | 2025-09-24 | The Methodist Hospital | Device for oncomagnetic treatment |
| KR102747887B1 (ko) | 2018-11-19 | 2024-12-27 | 노보큐어 게엠베하 | 선택적으로 주소 지정 가능한 하위 요소를 하지는 종양 치료장 제공을 위한 어레이 |
| SG11202101810SA (en) | 2018-11-29 | 2021-03-30 | Novocure Gmbh | Enhanced-flexibility transducer arrays for delivering ttfields (tumor treating fields) |
| CN113330485B (zh) | 2019-01-08 | 2025-09-26 | 诺沃库勒有限责任公司 | 评估将图像分割成不同类型组织的质量,用于使用肿瘤治疗场(TTField)来计划治疗 |
| US11554262B2 (en) | 2019-02-26 | 2023-01-17 | Novocure Gmbh | Determining a frequency for TTFields treatment based on an electrical characteristic of targeted cancer cells |
| EP3954314B1 (en) | 2019-02-27 | 2025-01-08 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
| EP3988099B1 (en) | 2019-03-29 | 2023-06-07 | Novocure GmbH | Methods for restoring sensitivity to ttfields in ttfields-resistant cancer cells with ptger3 inhibitors |
| WO2020207488A1 (zh) * | 2019-04-12 | 2020-10-15 | 上海必修福企业管理有限公司 | 空间电场的发生装置 |
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| US12343336B2 (en) | 2019-08-05 | 2025-07-01 | Novocure Gmbh | Increasing cancer cells' sensitivity to tumor treating fields (TTFields) by inhibiting IL11 activity |
| US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
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| WO2022190068A1 (en) | 2021-03-12 | 2022-09-15 | Novocure Gmbh | Methods of treating disease by skewing macrophage phenotype with alternating electric fields |
| WO2022200964A1 (en) * | 2021-03-23 | 2022-09-29 | Novocure Gmbh | Transducer apparatuses for delivering tumor treating fields to a subject's body |
| JP2024513854A (ja) | 2021-03-31 | 2024-03-27 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(TTFields)システムの電極を使用したインピーダンス断層撮影法 |
| TWI905187B (zh) * | 2021-05-11 | 2025-11-21 | 瑞士商諾萬可有限公司 | 用於治療子宮外孕的交變電場 |
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| JP2024545019A (ja) | 2021-12-30 | 2024-12-05 | ノボキュア ゲーエムベーハー | 腫瘍治療フィールド(ttfield)を使用した治療のためのパラメータ値の選択 |
| CN119013076A (zh) | 2022-03-30 | 2024-11-22 | 诺沃库勒有限责任公司 | 通过将换能器阵列配对在一起来使用交流电场治疗受试者的同时减少电敏 |
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| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| AU2017289870B2 (en) | 2016-06-30 | 2021-12-23 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
| CA2972699A1 (en) | 2016-07-10 | 2018-01-10 | Novocure Limited | Synchronizing tumor cells to the g2/m phase using ttfields combined with taxane or other anti-microtubule agents |
| KR102629400B1 (ko) | 2016-08-18 | 2024-01-24 | 노보큐어 리미티드 | 종양치료장을 전달하기 위한 어레이들 내의 온도 측정 |
| US11109773B2 (en) | 2016-12-13 | 2021-09-07 | Novocure Gmbh | Treating patients with TTFields with the electrode positions optimized using deformable templates |
| WO2018134733A1 (en) | 2017-01-19 | 2018-07-26 | Moshe Giladi | System for viewing cell cultures under a microscope whilst applying ttfields |
| US11298422B2 (en) | 2018-04-09 | 2022-04-12 | Novocure Gmbh | Treating tumors with TTFields and an aurora kinase inhibitor |
| PL3775956T3 (pl) | 2018-04-10 | 2022-10-10 | Novocure Gmbh | Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycji |
| CN116603165A (zh) | 2018-07-03 | 2023-08-18 | 斯坦福大学托管董事会 | 使用交变电场提高细胞膜通透性 |
| US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
| MX2020013431A (es) | 2018-07-18 | 2021-05-27 | Novocure Gmbh | Uso de densidad de perdida de potencia y mediciones relacionadas para cuantificar la dosis de campos de tratamiento de tumores (ttfield). |
| KR20250069692A (ko) | 2018-08-23 | 2025-05-19 | 카스텐 하게만 | 뇌-혈액 장벽 투과성을 향상시키기 위한 교번 전기장의 이용 |
| US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
| CN112770806B (zh) | 2018-09-07 | 2025-12-05 | 诺沃库勒有限责任公司 | 使用交变电场治疗自身免疫性疾病以减少t细胞的增殖 |
| US20200108031A1 (en) | 2018-10-05 | 2020-04-09 | Novocure Gmbh | Treating Tumors Using TTFields Combined with ABT-751 |
| CN113164525B (zh) | 2018-10-23 | 2025-03-14 | 利兰·斯坦福青年大学托管委员会 | 在基于干细胞的疗法中使用交变电场预防和治疗畸胎瘤形成 |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| US20200146586A1 (en) | 2018-11-14 | 2020-05-14 | Novocure Gmbh | Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images |
| KR102747887B1 (ko) | 2018-11-19 | 2024-12-27 | 노보큐어 게엠베하 | 선택적으로 주소 지정 가능한 하위 요소를 하지는 종양 치료장 제공을 위한 어레이 |
| SG11202101810SA (en) | 2018-11-29 | 2021-03-30 | Novocure Gmbh | Enhanced-flexibility transducer arrays for delivering ttfields (tumor treating fields) |
| CN113330485B (zh) | 2019-01-08 | 2025-09-26 | 诺沃库勒有限责任公司 | 评估将图像分割成不同类型组织的质量,用于使用肿瘤治疗场(TTField)来计划治疗 |
| KR20210130765A (ko) | 2019-02-22 | 2021-11-01 | 노보큐어 게엠베하 | Xelox, folfox 또는 이들의 각 구성 요소와 ttfield를 조합한 위암 치료 |
| US11554262B2 (en) | 2019-02-26 | 2023-01-17 | Novocure Gmbh | Determining a frequency for TTFields treatment based on an electrical characteristic of targeted cancer cells |
| EP3954314B1 (en) | 2019-02-27 | 2025-01-08 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
| EP3988099B1 (en) | 2019-03-29 | 2023-06-07 | Novocure GmbH | Methods for restoring sensitivity to ttfields in ttfields-resistant cancer cells with ptger3 inhibitors |
| EP3924039B1 (en) | 2019-04-17 | 2023-11-22 | Novocure GmbH | Uploading data from an isolated system without compromising isolation |
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2017
- 2017-04-03 US US15/478,066 patent/US10821283B2/en active Active
- 2017-04-04 CA CA3019474A patent/CA3019474A1/en active Pending
- 2017-04-04 EP EP17716642.8A patent/EP3439733B1/en active Active
- 2017-04-04 KR KR1020187030890A patent/KR102430229B1/ko active Active
- 2017-04-04 PT PT177166428T patent/PT3439733T/pt unknown
- 2017-04-04 CN CN201780024212.5A patent/CN109475735B/zh active Active
- 2017-04-04 EP EP19219639.2A patent/EP3693054B1/en active Active
- 2017-04-04 HU HUE17716642A patent/HUE048646T2/hu unknown
- 2017-04-04 CN CN202310518476.3A patent/CN116549848A/zh active Pending
- 2017-04-04 DK DK17716642.8T patent/DK3439733T3/da active
- 2017-04-04 EP EP23181273.6A patent/EP4234005A3/en active Pending
- 2017-04-04 ES ES17716642T patent/ES2779990T3/es active Active
- 2017-04-04 PL PL17716642T patent/PL3439733T3/pl unknown
- 2017-04-04 JP JP2019502289A patent/JP6896839B2/ja active Active
- 2017-04-04 WO PCT/IB2017/051898 patent/WO2017175116A1/en not_active Ceased
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2020
- 2020-09-30 US US17/038,950 patent/US11191956B2/en active Active
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2021
- 2021-06-08 JP JP2021095883A patent/JP7171827B2/ja active Active
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