PT3439733T - Redução da motilidade de células cancerosas usando campos de tratamento de tumores (ttfields) - Google Patents
Redução da motilidade de células cancerosas usando campos de tratamento de tumores (ttfields)Info
- Publication number
- PT3439733T PT3439733T PT177166428T PT17716642T PT3439733T PT 3439733 T PT3439733 T PT 3439733T PT 177166428 T PT177166428 T PT 177166428T PT 17716642 T PT17716642 T PT 17716642T PT 3439733 T PT3439733 T PT 3439733T
- Authority
- PT
- Portugal
- Prior art keywords
- ttfields
- cancer cells
- tumor treating
- treating fields
- reducing motility
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 2
- 201000011510 cancer Diseases 0.000 title 1
- 230000004899 motility Effects 0.000 title 1
Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Automation & Control Theory (AREA)
- Electrotherapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662317985P | 2016-04-04 | 2016-04-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3439733T true PT3439733T (pt) | 2020-03-25 |
Family
ID=58530601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT177166428T PT3439733T (pt) | 2016-04-04 | 2017-04-04 | Redução da motilidade de células cancerosas usando campos de tratamento de tumores (ttfields) |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10821283B2 (pt) |
| EP (3) | EP3693054B1 (pt) |
| JP (2) | JP6896839B2 (pt) |
| KR (1) | KR102430229B1 (pt) |
| CN (2) | CN109475735B (pt) |
| CA (1) | CA3019474A1 (pt) |
| DK (1) | DK3439733T3 (pt) |
| ES (1) | ES2779990T3 (pt) |
| HU (1) | HUE048646T2 (pt) |
| PL (1) | PL3439733T3 (pt) |
| PT (1) | PT3439733T (pt) |
| WO (1) | WO2017175116A1 (pt) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) * | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| US10441776B2 (en) | 2016-06-30 | 2019-10-15 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
| CN110178029B (zh) | 2017-01-19 | 2021-11-16 | 诺沃库勒有限责任公司 | 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统 |
| US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
| US20190117970A1 (en) | 2017-10-23 | 2019-04-25 | Cardiac Pacemakers, Inc. | Electric field shaping leads for treatment of cancer |
| US20190117969A1 (en) * | 2017-10-23 | 2019-04-25 | Cardiac Pacemakers, Inc. | Medical devices for treatment of cancer with electric fields |
| US20200368525A1 (en) * | 2017-11-17 | 2020-11-26 | Abbvie Inc. | Methods of Treating Glioblastoma |
| CN111683613B (zh) | 2017-12-26 | 2024-05-28 | 盖能适治疗股份有限公司 | 用于各种应用的能量输送的优化 |
| US10953209B2 (en) | 2018-03-28 | 2021-03-23 | Board Of Regents Of The University Of Texas System | Treating tumors using TTFields combined with a PARP inhibitor |
| CN112566665A (zh) | 2018-04-09 | 2021-03-26 | 莫舍·吉拉迪 | 用TTFields和Aurora激酶抑制剂治疗肿瘤 |
| KR102687814B1 (ko) | 2018-04-10 | 2024-07-24 | 지브 봄존 | 서로 다른 반복 시간을 가지는 두 개의 MRI 이미지들로부터 얻어진 1MHz 미만 저주파 교류 전도도 추산치 |
| JP7055906B2 (ja) * | 2018-07-03 | 2022-04-18 | エドウィン・チャン | 細胞膜透過性を増加させるための交流電界の使用 |
| US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
| US11583675B2 (en) * | 2018-07-10 | 2023-02-21 | Novocure Gmbh | Inhibiting viral infection using alternating electric fields |
| WO2020016840A1 (en) | 2018-07-18 | 2020-01-23 | Novocure Gmbh | Using power loss density and related measures to quantify the dose of tumor treating fields (ttfields) |
| JP7233453B2 (ja) * | 2018-08-23 | 2023-03-06 | ノボキュア ゲーエムベーハー | 血液脳関門の透過性を向上させるための交流電界の使用 |
| EP3892219B1 (en) * | 2018-08-23 | 2022-06-01 | Novocure GmbH | Using alternating electric fields to increase permeability of the blood brain barrier |
| WO2020047285A1 (en) * | 2018-08-29 | 2020-03-05 | Regents Of The University Of Minnesota | Devices and methods for treatment of tumors using electromagnetic signal |
| US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
| EP3846894A1 (en) | 2018-09-07 | 2021-07-14 | Novocure GmbH | Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| CN112930209B (zh) | 2018-10-15 | 2024-10-15 | 诺沃库勒有限责任公司 | 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields)的装置和方法 |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| EP4019080A1 (en) | 2018-11-19 | 2022-06-29 | Novocure GmbH | Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements |
| CN118079235A (zh) | 2018-11-29 | 2024-05-28 | 诺沃库勒有限责任公司 | 用于递送TTField（肿瘤治疗场）的增强灵活性换能器阵列 |
| EP3909015B1 (en) | 2019-01-08 | 2024-08-14 | Novocure GmbH | Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (ttfields) |
| JP2022522602A (ja) | 2019-02-26 | 2022-04-20 | ノボキュア ゲーエムベーハー | 標的がん細胞の電気特性に基づくｔｔフィールド治療のための周波数の決定 |
| EP3954314A1 (en) * | 2019-02-27 | 2022-02-16 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
| JP7419391B2 (ja) | 2019-03-29 | 2024-01-22 | ノボキュア ゲーエムベーハー | ＰＴＧＥＲ３阻害剤によりＴＴＦｉｅｌｄｓ－耐性がん細胞におけるＴＴＦｉｅｌｄｓに対する感受性を回復させるための方法 |
| CN111803792A (zh) * | 2019-04-12 | 2020-10-23 | 上海必修福企业管理有限公司 | 空间电场的发生装置 |
| EP3924039B1 (en) | 2019-04-17 | 2023-11-22 | Novocure GmbH | Uploading data from an isolated system without compromising isolation |
| WO2020219336A1 (en) | 2019-04-22 | 2020-10-29 | Boston Scientific Scimed, Inc. | Electrical stimulation devices for cancer treatment |
| WO2020219337A1 (en) * | 2019-04-22 | 2020-10-29 | Boston Scientific Scimed, Inc. | Systems for administering electrical stimulation to treat cancer |
| US12109412B2 (en) | 2019-04-22 | 2024-10-08 | Boston Scientific Scimed, Inc. | Combination electrical and chemotherapeutic treatment of cancer |
| US11607542B2 (en) | 2019-04-23 | 2023-03-21 | Boston Scientific Scimed, Inc. | Electrical stimulation for cancer treatment with internal and external electrodes |
| CN113766950A (zh) | 2019-04-23 | 2021-12-07 | 波士顿科学国际有限公司 | 带有热治疗或热监测的电刺激 |
| CN113747936B (zh) | 2019-04-23 | 2024-06-18 | 波士顿科学国际有限公司 | 用于电刺激来治疗癌症的电极 |
| WO2021019403A1 (en) | 2019-07-31 | 2021-02-04 | Yoram Wasserman | Applying tumor treating fields (ttfields) via electrodes embedded into skull implants |
| US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
| JP2023508990A (ja) * | 2019-12-26 | 2023-03-06 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 癌細胞における異常な解糖的代謝を正常化する方法 |
| EP4074370A1 (en) | 2019-12-31 | 2022-10-19 | Novocure GmbH | High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels |
| DK4074367T3 (da) | 2019-12-31 | 2023-05-22 | Novocure Gmbh | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
| CN115515674A (zh) | 2020-02-24 | 2022-12-23 | 波士顿科学国际有限公司 | 用于治疗胰腺癌的系统和方法 |
| KR102644003B1 (ko) | 2020-04-01 | 2024-03-07 | 한국전자통신연구원 | 암 치료 장치 |
| CN115916325A (zh) * | 2020-04-24 | 2023-04-04 | 诺沃库勒有限责任公司 | 使用交变电场增加血脑屏障的通透性 |
| JP2023525083A (ja) * | 2020-05-08 | 2023-06-14 | ノボキュア ゲーエムベーハー | 多能性幹細胞に交流電場を印加する組成物及び方法 |
| KR102464313B1 (ko) | 2020-05-18 | 2022-11-08 | 주식회사 필드큐어 | 전기장 암 치료 시스템을 위한 품질 보증 장치 및 방법 |
| EP4168108A4 (en) | 2020-06-19 | 2024-07-17 | The Methodist Hospital Dba Houston Methodist Hospital | METHOD AND APPARATUS FOR ONCOMAGNETIC TREATMENT |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| JP7498290B2 (ja) * | 2020-06-30 | 2024-06-11 | ノボキュア ゲーエムベーハー | 腫瘍治療電場（ｔｔフィールド）を印加するためのポリマー絶縁層を備えるフレキシブルトランスデューサアレイ |
| KR20230073173A (ko) | 2020-09-25 | 2023-05-25 | 노보큐어 게엠베하 | 과열 없이 전류를 최대화하기 위해 종양 치료 필드(ttfields) 시스템의 개별 전극 요소에 대한 금속화 영역 변경 |
| JP7145280B2 (ja) * | 2020-10-13 | 2022-09-30 | Ｔｖｓ Ｒｅｇｚａ株式会社 | 送受信方法 |
| KR102519139B1 (ko) | 2020-11-25 | 2023-04-25 | 주식회사 필드큐어 | 회전하는 교류 전기장을 이용한 전기장 인가 장치 및 방법 |
| EP4210811B1 (en) | 2020-12-21 | 2024-10-23 | Novocure GmbH | Optimization of composite electrode |
| IT202100000119A1 (it) | 2021-01-05 | 2022-07-05 | Telea Electronic Eng Srl | Dispositivo e farmaco antitumorale per il trattamento di cellule neoplastiche |
| WO2022167939A1 (en) * | 2021-02-03 | 2022-08-11 | Novocure Gmbh | Varying parameters of tumor treating fields (ttfields) treatment to overcome treatment resistance |
| IL314390A (en) * | 2022-03-30 | 2024-09-01 | Novocure Gmbh | Use of combined cooling periods to increase the peak strength of fields treating growth |
| US20230310877A1 (en) * | 2022-03-30 | 2023-10-05 | Novocure Gmbh | Reducing Electrosensation Whilst Treating a Subject Using Alternating Electric Fields by Pairing Transducer Arrays Together |
| WO2024090939A1 (ko) * | 2022-10-25 | 2024-05-02 | 주식회사 필드큐어 | 전기장 전달 시스템 및 방법 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5873849A (en) | 1997-04-24 | 1999-02-23 | Ichor Medical Systems, Inc. | Electrodes and electrode arrays for generating electroporation inducing electrical fields |
| US6326177B1 (en) * | 1999-08-04 | 2001-12-04 | Eastern Virginia Medical School Of The Medical College Of Hampton Roads | Method and apparatus for intracellular electro-manipulation |
| US7599746B2 (en) | 2000-02-17 | 2009-10-06 | Standen Ltd | Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases |
| US7136699B2 (en) | 2002-10-02 | 2006-11-14 | Standen, Ltd. | Apparatus for destroying dividing cells |
| AU3399801A (en) | 2000-02-17 | 2001-08-27 | Yoram Palti | Method and apparatus for destroying dividing cells |
| US8447395B2 (en) | 2000-02-17 | 2013-05-21 | Novocure Ltd | Treating bacteria with electric fields |
| US7089054B2 (en) | 2002-10-02 | 2006-08-08 | Standen Ltd. | Apparatus and method for treating a tumor or the like |
| US7016725B2 (en) * | 2001-11-06 | 2006-03-21 | Standen Ltd. | Method and apparatus for destroying dividing cells |
| US6868289B2 (en) | 2002-10-02 | 2005-03-15 | Standen Ltd. | Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor |
| US8175698B2 (en) | 2000-02-17 | 2012-05-08 | Novocure Ltd. | Treating bacteria with electric fields |
| US6546290B1 (en) | 2000-04-12 | 2003-04-08 | Roamitron Holding S.A. | Method and apparatus for electromedical therapy |
| US6904322B2 (en) | 2002-02-15 | 2005-06-07 | Kalaco Scientific, Inc. | Transcranial electrostimulation apparatus and method |
| JP4750784B2 (ja) * | 2004-04-23 | 2011-08-17 | ノヴォキュアー・リミテッド | 異なる周波数の電界による腫瘍等の治療 |
| DK1833552T3 (da) | 2004-12-07 | 2010-08-02 | Standen Ltd | Elektroder til anbringelse af et elektrisk felt in-vivo i en længere tidsperiode |
| CA2594231C (en) | 2004-12-27 | 2016-04-19 | Standen Ltd. | Treating a tumor or the like with electric fields at different orientations |
| US20060173493A1 (en) | 2005-01-28 | 2006-08-03 | Cyberonics, Inc. | Multi-phasic signal for stimulation by an implantable device |
| EP3804809B1 (en) * | 2005-10-03 | 2023-12-27 | Novocure GmbH | Optimizing characteristics of an electric field to increase the field's effect on proliferating cells |
| US8019414B2 (en) | 2006-04-05 | 2011-09-13 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with other treatment regimens |
| DK2167194T3 (en) | 2007-03-06 | 2017-06-19 | Novocure Ltd | TREATMENT OF CANCER USING ELECTROMAGNETIC FIELDS IN COMBINATION WITH PHOTODYNAMIC THERAPY |
| JP5485153B2 (ja) * | 2007-08-14 | 2014-05-07 | ノボキュア リミテッド | 電界による寄生生物治療 |
| US8715203B2 (en) | 2007-09-17 | 2014-05-06 | Novocure Limited | Composite electrode |
| US9655669B2 (en) | 2013-05-06 | 2017-05-23 | Novocure Limited | Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment |
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US20190117963A1 (en) | 2014-07-25 | 2019-04-25 | Loyalty Based Innovations, LLC | Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields |
| US9833617B2 (en) | 2014-07-25 | 2017-12-05 | Loyalty Based Innovations, LLC | Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| US10441776B2 (en) | 2016-06-30 | 2019-10-15 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
| US20180008708A1 (en) | 2016-07-10 | 2018-01-11 | Novocure Limited | Synchronizing Tumor Cells to the G2/M Phase Using TTFields Combined with Taxane or Other Anti-Microtubule Agents |
| EP4218905A1 (en) | 2016-08-18 | 2023-08-02 | Novocure GmbH | Temperature measurement in arrays for delivering tumour treating fields |
| JP7184774B2 (ja) | 2016-12-13 | 2022-12-06 | ノボキュア ゲーエムベーハー | 変形可能テンプレートを使用して最適化された電極位置を有するｔｔフィールドを用いて患者を治療する |
| CN110178029B (zh) | 2017-01-19 | 2021-11-16 | 诺沃库勒有限责任公司 | 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统 |
| CN112566665A (zh) | 2018-04-09 | 2021-03-26 | 莫舍·吉拉迪 | 用TTFields和Aurora激酶抑制剂治疗肿瘤 |
| KR102687814B1 (ko) | 2018-04-10 | 2024-07-24 | 지브 봄존 | 서로 다른 반복 시간을 가지는 두 개의 MRI 이미지들로부터 얻어진 1MHz 미만 저주파 교류 전도도 추산치 |
| JP7055906B2 (ja) | 2018-07-03 | 2022-04-18 | エドウィン・チャン | 細胞膜透過性を増加させるための交流電界の使用 |
| US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
| WO2020016840A1 (en) | 2018-07-18 | 2020-01-23 | Novocure Gmbh | Using power loss density and related measures to quantify the dose of tumor treating fields (ttfields) |
| EP3892219B1 (en) | 2018-08-23 | 2022-06-01 | Novocure GmbH | Using alternating electric fields to increase permeability of the blood brain barrier |
| US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
| EP3846894A1 (en) | 2018-09-07 | 2021-07-14 | Novocure GmbH | Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells |
| US20200108031A1 (en) | 2018-10-05 | 2020-04-09 | Novocure Gmbh | Treating Tumors Using TTFields Combined with ABT-751 |
| JP7282411B2 (ja) | 2018-10-23 | 2023-05-29 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 交流電場を使用する、幹細胞に基づく療法におけるテラトーマ形成の予防及び処置 |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| US20200146586A1 (en) | 2018-11-14 | 2020-05-14 | Novocure Gmbh | Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images |
| EP4019080A1 (en) | 2018-11-19 | 2022-06-29 | Novocure GmbH | Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements |
| CN118079235A (zh) | 2018-11-29 | 2024-05-28 | 诺沃库勒有限责任公司 | 用于递送TTField（肿瘤治疗场）的增强灵活性换能器阵列 |
| EP3909015B1 (en) | 2019-01-08 | 2024-08-14 | Novocure GmbH | Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (ttfields) |
| WO2020170164A1 (en) | 2019-02-22 | 2020-08-27 | Moshe Giladi | Treating gastric cancer using ttfields combined with xelox or folfox |
| JP2022522602A (ja) | 2019-02-26 | 2022-04-20 | ノボキュア ゲーエムベーハー | 標的がん細胞の電気特性に基づくｔｔフィールド治療のための周波数の決定 |
| EP3954314A1 (en) | 2019-02-27 | 2022-02-16 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
| JP7419391B2 (ja) | 2019-03-29 | 2024-01-22 | ノボキュア ゲーエムベーハー | ＰＴＧＥＲ３阻害剤によりＴＴＦｉｅｌｄｓ－耐性がん細胞におけるＴＴＦｉｅｌｄｓに対する感受性を回復させるための方法 |
| EP3924039B1 (en) | 2019-04-17 | 2023-11-22 | Novocure GmbH | Uploading data from an isolated system without compromising isolation |
-
2017
- 2017-04-03 US US15/478,066 patent/US10821283B2/en active Active
- 2017-04-04 CN CN201780024212.5A patent/CN109475735B/zh active Active
- 2017-04-04 ES ES17716642T patent/ES2779990T3/es active Active
- 2017-04-04 KR KR1020187030890A patent/KR102430229B1/ko active IP Right Grant
- 2017-04-04 CA CA3019474A patent/CA3019474A1/en active Pending
- 2017-04-04 WO PCT/IB2017/051898 patent/WO2017175116A1/en active Application Filing
- 2017-04-04 CN CN202310518476.3A patent/CN116549848A/zh active Pending
- 2017-04-04 EP EP19219639.2A patent/EP3693054B1/en active Active
- 2017-04-04 PL PL17716642T patent/PL3439733T3/pl unknown
- 2017-04-04 HU HUE17716642A patent/HUE048646T2/hu unknown
- 2017-04-04 EP EP23181273.6A patent/EP4234005A3/en active Pending
- 2017-04-04 EP EP17716642.8A patent/EP3439733B1/en active Active
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- 2017-04-04 PT PT177166428T patent/PT3439733T/pt unknown
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2020
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2021
- 2021-06-08 JP JP2021095883A patent/JP7171827B2/ja active Active
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| PL3439733T3 (pl) | 2020-07-27 |
| CA3019474A1 (en) | 2017-10-12 |
| US10821283B2 (en) | 2020-11-03 |
| EP3693054A3 (en) | 2020-10-28 |
| JP2019510606A (ja) | 2019-04-18 |
| CN109475735A (zh) | 2019-03-15 |
| EP3693054A2 (en) | 2020-08-12 |
| US11191956B2 (en) | 2021-12-07 |
| CN109475735B (zh) | 2023-05-23 |
| EP3439733A1 (en) | 2019-02-13 |
| HUE048646T2 (hu) | 2020-08-28 |
| JP2021126552A (ja) | 2021-09-02 |
| EP3693054B1 (en) | 2023-06-28 |
| KR20180133431A (ko) | 2018-12-14 |
| EP3693054C0 (en) | 2023-06-28 |
| EP4234005A2 (en) | 2023-08-30 |
| EP4234005A3 (en) | 2024-01-10 |
| US20210008367A1 (en) | 2021-01-14 |
| WO2017175116A1 (en) | 2017-10-12 |
| US20170281934A1 (en) | 2017-10-05 |
| JP6896839B2 (ja) | 2021-06-30 |
| EP3439733B1 (en) | 2019-12-25 |
| DK3439733T3 (da) | 2020-03-23 |
| JP7171827B2 (ja) | 2022-11-15 |
| ES2779990T3 (es) | 2020-08-21 |
| CN116549848A (zh) | 2023-08-08 |
| KR102430229B1 (ko) | 2022-08-05 |
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