DK3804809T3 - Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler - Google Patents
Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler Download PDFInfo
- Publication number
- DK3804809T3 DK3804809T3 DK20210399.0T DK20210399T DK3804809T3 DK 3804809 T3 DK3804809 T3 DK 3804809T3 DK 20210399 T DK20210399 T DK 20210399T DK 3804809 T3 DK3804809 T3 DK 3804809T3
- Authority
- DK
- Denmark
- Prior art keywords
- field
- optimizing
- enhance
- properties
- effect
- Prior art date
Links
- 230000000694 effects Effects 0.000 title 1
- 230000005684 electric field Effects 0.000 title 1
- 230000002062 proliferating effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36034—Control systems specified by the stimulation parameters
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Electrotherapy Devices (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72356005P | 2005-10-03 | 2005-10-03 | |
EP15151025.2A EP2902075B1 (en) | 2005-10-03 | 2006-09-29 | Optimizing characteristics of an electric field to increase the field's effect on proliferating cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3804809T3 true DK3804809T3 (da) | 2024-02-12 |
Family
ID=37836745
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK20210399.0T DK3804809T3 (da) | 2005-10-03 | 2006-09-29 | Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler |
DK06820767T DK1933937T3 (da) | 2005-10-03 | 2006-09-29 | Optimering af karakteristika af et elektrisk felt for at øge feltets effekt på prolifererende celler |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06820767T DK1933937T3 (da) | 2005-10-03 | 2006-09-29 | Optimering af karakteristika af et elektrisk felt for at øge feltets effekt på prolifererende celler |
Country Status (9)
Country | Link |
---|---|
US (2) | US7917227B2 (da) |
EP (3) | EP2902075B1 (da) |
JP (1) | JP2009520509A (da) |
CN (3) | CN112402798B (da) |
CA (1) | CA2624624C (da) |
DK (2) | DK3804809T3 (da) |
ES (1) | ES2534488T3 (da) |
PT (2) | PT3804809T (da) |
WO (1) | WO2007039799A2 (da) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8447395B2 (en) * | 2000-02-17 | 2013-05-21 | Novocure Ltd | Treating bacteria with electric fields |
CA2400526C (en) | 2000-02-17 | 2013-04-23 | Yoram Palti | Method and apparatus for destroying dividing cells |
US8175698B2 (en) | 2000-02-17 | 2012-05-08 | Novocure Ltd. | Treating bacteria with electric fields |
US7890183B2 (en) * | 2000-02-17 | 2011-02-15 | Novocure Ltd. | Treating parasites with electric fields |
CA2563817C (en) | 2004-04-23 | 2018-07-10 | Yoram Palti | Treating a tumor or the like with electric fields at different frequencies |
ATE463277T1 (de) * | 2004-12-07 | 2010-04-15 | Standen Ltd | Elektroden zum anlegen eines elektrischen felds in vivo über einen längeren zeitraum |
JP2009520509A (ja) * | 2005-10-03 | 2009-05-28 | ノヴォキュアー・リミテッド | 増殖細胞における電場の効果を増大させるための電場の最適化特性 |
US8019414B2 (en) * | 2006-04-05 | 2011-09-13 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with other treatment regimens |
WO2008034107A2 (en) * | 2006-09-14 | 2008-03-20 | Lazure Technologies, Llc | Tissue ablation and removal |
WO2009044289A1 (en) * | 2007-03-06 | 2009-04-09 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with photodynamic therapy |
US20090076500A1 (en) * | 2007-09-14 | 2009-03-19 | Lazure Technologies, Llc | Multi-tine probe and treatment by activation of opposing tines |
US8562602B2 (en) * | 2007-09-14 | 2013-10-22 | Lazure Technologies, Llc | Multi-layer electrode ablation probe and related methods |
CN101854977B (zh) | 2007-09-14 | 2015-09-09 | 拉热尔技术有限公司 | 前列腺癌消融 |
US20100100093A1 (en) * | 2008-09-16 | 2010-04-22 | Lazure Technologies, Llc. | System and method for controlled tissue heating for destruction of cancerous cells |
US8728139B2 (en) | 2009-04-16 | 2014-05-20 | Lazure Technologies, Llc | System and method for energy delivery to a tissue using an electrode array |
US9526911B1 (en) | 2010-04-27 | 2016-12-27 | Lazure Scientific, Inc. | Immune mediated cancer cell destruction, systems and methods |
US8684901B1 (en) | 2010-11-22 | 2014-04-01 | Jacob Zabara | Electromagnetic radiation treatment for cancer and pathological genetic regulations |
US9233257B1 (en) | 2010-11-22 | 2016-01-12 | Jacob Zabara | Electromagnetic radiation treatment |
EP2676143B1 (en) | 2011-02-15 | 2023-11-01 | Hemosonics, Llc | Characterization of blood hemostasis and oxygen transport parameters |
US9655669B2 (en) | 2013-05-06 | 2017-05-23 | Novocure Limited | Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment |
US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
US9726647B2 (en) | 2015-03-17 | 2017-08-08 | Hemosonics, Llc | Determining mechanical properties via ultrasound-induced resonance |
US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
AU2017289870B2 (en) | 2016-06-30 | 2021-12-23 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
CN110178029B (zh) | 2017-01-19 | 2021-11-16 | 诺沃库勒有限责任公司 | 用于在施加TTFields的同时在显微镜下观察细胞培养物的系统 |
US11364390B2 (en) * | 2017-02-07 | 2022-06-21 | Santi Tofani | Apparatus for treating pathological cells |
CN106823125A (zh) * | 2017-03-24 | 2017-06-13 | 长沙利星医药科技开发有限公司 | 一种采用调幅电场增强药物疗效的装置 |
US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
US20190117971A1 (en) * | 2017-10-23 | 2019-04-25 | Cardiac Pacemakers, Inc. | Volume-filling leads for treatment of cancer with electric fields |
US20190117969A1 (en) * | 2017-10-23 | 2019-04-25 | Cardiac Pacemakers, Inc. | Medical devices for treatment of cancer with electric fields |
CN111601641B (zh) | 2017-11-07 | 2022-06-07 | 伊凡斯克医疗公司 | 用于通过倏逝波治疗肿瘤的装置 |
CN118383863A (zh) | 2017-12-26 | 2024-07-26 | 盖能适治疗股份有限公司 | 用于各种应用的能量输送的优化 |
US10953209B2 (en) | 2018-03-28 | 2021-03-23 | Board Of Regents Of The University Of Texas System | Treating tumors using TTFields combined with a PARP inhibitor |
JP7139448B2 (ja) | 2018-04-09 | 2022-09-20 | ノボキュア ゲーエムベーハー | TTFields及びオーロラキナーゼ阻害剤による腫瘍の治療 |
CN112424626A (zh) | 2018-04-10 | 2021-02-26 | 吉夫·波姆桑 | 从具有不同重复时间的两个mri图像导出的低频(<1mhz)ac电导率估计 |
AU2019299533B2 (en) | 2018-07-03 | 2023-03-09 | Novocure Gmbh | Using alternating electric fields to increase cell membrane permeability |
US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
JP7366990B2 (ja) | 2018-07-10 | 2023-10-23 | ノボキュア ゲーエムベーハー | 交流電場を用いたウイルス感染の抑制 |
MX2020013431A (es) | 2018-07-18 | 2021-05-27 | Novocure Gmbh | Uso de densidad de perdida de potencia y mediciones relacionadas para cuantificar la dosis de campos de tratamiento de tumores (ttfield). |
WO2020021896A1 (ja) * | 2018-07-25 | 2020-01-30 | エイブル株式会社 | 細胞刺激装置、細胞刺激方法、培養生成物の製造方法、単離細胞の製造方法及び細胞増殖方法 |
HUE059062T2 (hu) * | 2018-08-23 | 2022-10-28 | Novocure Gmbh | Váltakozó elektromos mezõk alkalmazása vér-agy gát permeabilitásának növelésére |
WO2020047285A1 (en) | 2018-08-29 | 2020-03-05 | Regents Of The University Of Minnesota | Devices and methods for treatment of tumors using electromagnetic signal |
US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
US11020585B2 (en) | 2018-09-07 | 2021-06-01 | Novocure Gmbh | Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells |
PL3984590T3 (pl) | 2018-10-15 | 2023-05-02 | Novocure Gmbh | Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu |
WO2020084596A1 (en) | 2018-10-25 | 2020-04-30 | Zeev Bomzon | Delivering alternating electric fields (e.g., ttfields) to a subject's spinal anatomy |
US11395916B2 (en) | 2018-11-19 | 2022-07-26 | Novocure Gmbh | Arrays for delivering tumor treating fields (TTFields) with selectively addressable sub-elements |
MX2021002625A (es) | 2018-11-29 | 2021-05-12 | Novocure Gmbh | Arreglos de transductores de mayor flexibilidad para suministrar campos tt (campos de tratamiento de tumores). |
JP7246486B2 (ja) | 2019-01-08 | 2023-03-27 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(ttfields)を使用した治療を計画するための異なるタイプの組織への画像のセグメンテーションの品質評価 |
CN113573774A (zh) | 2019-02-26 | 2021-10-29 | 诺沃库勒有限责任公司 | 基于靶向癌细胞的电特性确定TTfield治疗的频率 |
US11471676B2 (en) | 2019-02-27 | 2022-10-18 | Novocure Gmbh | Delivering tumor treating fields (TTFields) using implantable transducer arrays |
CN113613651A (zh) | 2019-03-29 | 2021-11-05 | 诺沃库勒有限责任公司 | 用PTGER3抑制剂恢复TTField抗性癌细胞中对TTField的敏感性的方法 |
EP3924039B1 (en) | 2019-04-17 | 2023-11-22 | Novocure GmbH | Uploading data from an isolated system without compromising isolation |
JP7410176B2 (ja) | 2019-04-22 | 2024-01-09 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 癌を治療するために電気刺激を与えるためのシステム |
CN113766948A (zh) | 2019-04-22 | 2021-12-07 | 波士顿科学国际有限公司 | 对癌症的电与化学组合治疗 |
JP2022530872A (ja) | 2019-04-22 | 2022-07-04 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 癌治療のための電気刺激機器 |
WO2020219517A2 (en) | 2019-04-23 | 2020-10-29 | Boston Scientific Scimed, Inc. | Electrical stimulation for cancer treatment with internal and external electrodes |
EP3958956B1 (en) | 2019-04-23 | 2024-02-28 | Boston Scientific Scimed Inc. | Electrodes for electrical stimulation to treat cancer |
JP7476231B2 (ja) | 2019-04-23 | 2024-04-30 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 温熱療法又は熱モニタと共に行われる電気刺激 |
JP7472264B2 (ja) | 2019-07-31 | 2024-04-22 | ノボキュア ゲーエムベーハー | 頭蓋骨インプラントに埋め込まれた電極による腫瘍治療電場(ttフィールド)の印加 |
CN114364433A (zh) | 2019-08-30 | 2022-04-15 | 诺沃库勒有限责任公司 | 向颈部输送肿瘤治疗场(TTFields) |
EP4134127A1 (en) * | 2019-11-21 | 2023-02-15 | Novocure GmbH | Apparatus for providing tumor treating fields |
EP4074369A1 (en) | 2019-12-31 | 2022-10-19 | Novocure GmbH | High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels |
DK4074367T3 (da) | 2019-12-31 | 2023-05-22 | Novocure Gmbh | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
EP4110455B1 (en) | 2020-02-24 | 2024-05-22 | Boston Scientific Scimed, Inc. | Systems for treatment of pancreatic cancer |
WO2021257967A1 (en) | 2020-06-19 | 2021-12-23 | The Methodist Hospital Dba Houston Methodist Hospital | Method and apparatus for oncomagnetic treatment |
US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
CN116367882A (zh) | 2020-09-25 | 2023-06-30 | 诺沃库勒有限责任公司 | 改变肿瘤治疗场(ttfield)系统中个体电极元件上的金属化面积以使电流最大化而不会过热 |
JP2023543301A (ja) | 2020-09-30 | 2023-10-13 | ノボキュア ゲーエムベーハー | 腫瘍治療電場を形成するための植込み可能アレイ |
JP2023553333A (ja) * | 2020-11-25 | 2023-12-21 | ノボキュア ゲーエムベーハー | ピーク強度での腫瘍治療電場(ttfield)を時間の半分未満で印加することでttfieldの有効性を高めること |
KR102519139B1 (ko) * | 2020-11-25 | 2023-04-25 | 주식회사 필드큐어 | 회전하는 교류 전기장을 이용한 전기장 인가 장치 및 방법 |
US20220241603A1 (en) * | 2021-02-03 | 2022-08-04 | Novocure Gmbh | Varying Parameters of Tumor Treating Fields (TTFields) Treatment to Overcome Treatment Resistance |
CN113005037B (zh) * | 2021-04-12 | 2024-05-28 | 深圳市第二人民医院(深圳市转化医学研究院) | 一种用于细胞培养的电极绝缘垫及其非接触电场装置和方法 |
WO2023051843A1 (zh) * | 2021-09-28 | 2023-04-06 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统 |
WO2023051844A1 (zh) * | 2021-09-28 | 2023-04-06 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统 |
CN114146311A (zh) * | 2021-12-31 | 2022-03-08 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统及电场施加方法 |
WO2023051845A1 (zh) * | 2021-09-28 | 2023-04-06 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统 |
CN114177528A (zh) * | 2021-12-31 | 2022-03-15 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统及其电场施加方法 |
WO2023051846A1 (zh) * | 2021-09-28 | 2023-04-06 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗系统 |
WO2024141898A1 (en) * | 2022-12-27 | 2024-07-04 | Novocure Gmbh | Multi-channel device for directional shaping of electric fields e.g., tumor treating fields (ttfields) |
WO2024201323A1 (en) * | 2023-03-31 | 2024-10-03 | Novocure Gmbh | Applying tumor treating fields (ttfields) to a body part in at least three different directions using five arrays of electrode elements |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR446660A (fr) | 1911-09-02 | 1912-12-12 | Gottlieb Schuettel | Dispositif pour métiers continus à anneaux pour monter les curseurs sur les anneaux |
AT315357B (de) * | 1970-09-08 | 1974-05-27 | Rodler Ing Hans | Elektromedizinischer Apparat zur Erzeugung von Interferenz- und Schwebungsströmen |
BE794566A (fr) | 1972-01-28 | 1973-07-26 | Esb Inc | Regenerateur et stimulateur bioelectrochimique et procedes d'application in vivo d'energie electrique a des cellules et des tissus. |
US3991770A (en) * | 1974-01-24 | 1976-11-16 | Leveen Harry H | Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation |
US4016886A (en) | 1974-11-26 | 1977-04-12 | The United States Of America As Represented By The United States Energy Research And Development Administration | Method for localizing heating in tumor tissue |
US4121592A (en) | 1975-08-04 | 1978-10-24 | Critical Systems, Inc. | Apparatus for heating tissue |
DE2907013A1 (de) | 1978-02-24 | 1979-08-30 | American Med Syst | Verfahren und vorrichtung zum beguenstigen der heilung von verletzten knochenknorpeln und geweben im gesichtsbereich |
DE2813068A1 (de) | 1978-03-25 | 1979-10-04 | Philips Patentverwaltung | Verfahren und vorrichtung zur ermittlung von inneren koerperstrukturen |
GB2043453A (en) | 1979-02-22 | 1980-10-08 | Electrochem Tech Corp | Improvements in or relating to an electrode |
US4285346A (en) * | 1979-03-14 | 1981-08-25 | Harry V. LeVeen | Electrode system |
US4472506A (en) | 1981-01-13 | 1984-09-18 | Liburdy Robert P | Method for determining cell membrane dielectric breakdown |
US4467809A (en) | 1982-09-17 | 1984-08-28 | Biolectron, Inc. | Method for non-invasive electrical stimulation of epiphyseal plate growth |
US4622952A (en) | 1983-01-13 | 1986-11-18 | Gordon Robert T | Cancer treatment method |
CA1244889A (en) | 1983-01-24 | 1988-11-15 | Kureha Chemical Ind Co Ltd | HYPERTHERMIA DEVICE |
DE3323415C2 (de) | 1983-06-29 | 1985-04-25 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Verwendung eines Verfahrens und einer Vorrichtung zur Bestimmung von Zellinhaltstoffe sezernierenden Zellen |
SE455920B (sv) | 1986-01-29 | 1988-08-22 | Hans Wiksell | Anordning for hypertermibehandling av tumorer |
US4923814A (en) | 1986-05-09 | 1990-05-08 | Electropore, Inc. | High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor |
CN86103803B (zh) | 1986-06-05 | 1987-11-18 | 北京信息工程学院 | 静电场治疗装置 |
US4822470A (en) | 1987-10-09 | 1989-04-18 | Baylor College Of Medicine | Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses |
US4936303A (en) | 1987-11-20 | 1990-06-26 | Ultrathermics | Ultrasonic heating apparatus and method |
JPH0629196B2 (ja) | 1987-12-01 | 1994-04-20 | 甲子郎 梅村 | 超音波による腫瘍治療用生理作用増強剤 |
US5389069A (en) | 1988-01-21 | 1995-02-14 | Massachusetts Institute Of Technology | Method and apparatus for in vivo electroporation of remote cells and tissue |
FR2627987B3 (fr) | 1988-03-04 | 1990-02-02 | Indiba Sa | Appareil electronique pour la therapie medicale et cosmetique |
US4848347A (en) * | 1988-04-04 | 1989-07-18 | Dynatronics Laser Corporation | Interferential electrical current therapy systems and methods |
US5158071A (en) | 1988-07-01 | 1992-10-27 | Hitachi, Ltd. | Ultrasonic apparatus for therapeutical use |
GB2223949B (en) * | 1988-09-08 | 1992-07-08 | Orthomedic Electronics Limited | Apparatus for functional electrical stimulation |
GB8904998D0 (en) | 1989-03-04 | 1989-04-19 | Matthews Tony | Anaesthetising apparatus |
US5099756A (en) | 1989-06-01 | 1992-03-31 | Harry H. Leveen | Radio frequency thermotherapy |
US5441746A (en) | 1989-12-22 | 1995-08-15 | Molecular Bioquest, Inc. | Electromagnetic wave absorbing, surface modified magnetic particles for use in medical applications, and their method of production |
US5236410A (en) | 1990-08-02 | 1993-08-17 | Ferrotherm International, Inc. | Tumor treatment method |
JP3072529B2 (ja) * | 1991-02-26 | 2000-07-31 | 三菱樹脂株式会社 | ストレッチ包装用フィルム |
CA2109084C (en) | 1991-05-03 | 2004-02-24 | John William Fisher Costerton | Biofilm reduction method |
US5441532A (en) | 1991-06-26 | 1995-08-15 | Massachusetts Institute Of Technology | Adaptive focusing and nulling hyperthermia annular and monopole phased array applicators |
US5468223A (en) | 1992-11-30 | 1995-11-21 | C.N.R.S. Paris | Electrochemotherapy |
US5386837A (en) | 1993-02-01 | 1995-02-07 | Mmtc, Inc. | Method for enhancing delivery of chemotherapy employing high-frequency force fields |
FR2703253B1 (fr) | 1993-03-30 | 1995-06-23 | Centre Nat Rech Scient | Applicateur d'impulsions electriques pour traitement de tissus biologiques. |
US5549656A (en) * | 1993-08-16 | 1996-08-27 | Med Serve Group, Inc. | Combination neuromuscular stimulator and electromyograph system |
IL108775A (en) | 1994-02-25 | 2003-09-17 | Univ Ramot | Method for efficient incorporation of molecules into cells |
US5704355A (en) | 1994-07-01 | 1998-01-06 | Bridges; Jack E. | Non-invasive system for breast cancer detection |
WO1997004830A1 (en) | 1995-07-28 | 1997-02-13 | Gray James R | Use of a polarizing field to modify the efficacy of a bioactive agent |
US5891182A (en) * | 1995-10-11 | 1999-04-06 | Regeneration Tech | Bio-active frequency generator and method |
US5606971A (en) | 1995-11-13 | 1997-03-04 | Artann Corporation, A Nj Corp. | Method and device for shear wave elasticity imaging |
US5718246A (en) | 1996-01-03 | 1998-02-17 | Preferential, Inc. | Preferential induction of electrically mediated cell death from applied pulses |
US5984882A (en) | 1996-08-19 | 1999-11-16 | Angiosonics Inc. | Methods for prevention and treatment of cancer and other proliferative diseases with ultrasonic energy |
US5869326A (en) | 1996-09-09 | 1999-02-09 | Genetronics, Inc. | Electroporation employing user-configured pulsing scheme |
US6021347A (en) * | 1996-12-05 | 2000-02-01 | Herbst; Ewa | Electrochemical treatment of malignant tumors |
US5776173A (en) * | 1997-06-04 | 1998-07-07 | Madsen, Jr.; Ronald E. | Programmable interferential stimulator |
WO1999001175A1 (en) * | 1997-06-30 | 1999-01-14 | Rhone-Poulenc Rorer S.A. | Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo |
US6055453A (en) | 1997-08-01 | 2000-04-25 | Genetronics, Inc. | Apparatus for addressing needle array electrodes for electroporation therapy |
EP1003847A4 (en) | 1997-09-04 | 2005-04-06 | Science Res Lab Inc | SEPARATION OF CELLS BY USE OF ELECTRIC FIELDS |
DE19757720A1 (de) * | 1997-12-23 | 1999-06-24 | Sulzer Osypka Gmbh | Verfahren zum Betrieb einer Hochfrequenz-Ablationsvorrichtung und Vorrichtung für die Hochfrequenz-Gewebe-Ablation |
US6208893B1 (en) * | 1998-01-27 | 2001-03-27 | Genetronics, Inc. | Electroporation apparatus with connective electrode template |
US6027488A (en) | 1998-06-03 | 2000-02-22 | Genetronics, Inc. | Flow-through electroporation system for ex vivo gene therapy |
US5976092A (en) | 1998-06-15 | 1999-11-02 | Chinn; Douglas O. | Combination stereotactic surgical guide and ultrasonic probe |
US6319901B1 (en) | 1998-10-15 | 2001-11-20 | Ichor Medical Systems, Inc. | Methods for prolonging cell membrane permeability |
JP4102031B2 (ja) | 1999-03-09 | 2008-06-18 | サーメイジ インコーポレイテッド | 組織を治療するのための装置および方法 |
US6678558B1 (en) | 1999-03-25 | 2004-01-13 | Genetronics, Inc. | Method and apparatus for reducing electroporation-mediated muscle reaction and pain response |
US6366808B1 (en) | 2000-03-13 | 2002-04-02 | Edward A. Schroeppel | Implantable device and method for the electrical treatment of cancer |
US6853864B2 (en) | 2000-02-02 | 2005-02-08 | Catholic University Of America, The | Use of electromagnetic fields in cancer and other therapies |
US6868289B2 (en) | 2002-10-02 | 2005-03-15 | Standen Ltd. | Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor |
CA2400526C (en) * | 2000-02-17 | 2013-04-23 | Yoram Palti | Method and apparatus for destroying dividing cells |
US7890183B2 (en) * | 2000-02-17 | 2011-02-15 | Novocure Ltd. | Treating parasites with electric fields |
US7136699B2 (en) * | 2002-10-02 | 2006-11-14 | Standen, Ltd. | Apparatus for destroying dividing cells |
US7599746B2 (en) | 2000-02-17 | 2009-10-06 | Standen Ltd | Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases |
US7146210B2 (en) | 2000-02-17 | 2006-12-05 | Standen Ltd. | Apparatus and method for optimizing tumor treatment efficiency by electric fields |
US7089054B2 (en) | 2002-10-02 | 2006-08-08 | Standen Ltd. | Apparatus and method for treating a tumor or the like |
US8175698B2 (en) * | 2000-02-17 | 2012-05-08 | Novocure Ltd. | Treating bacteria with electric fields |
US7016725B2 (en) | 2001-11-06 | 2006-03-21 | Standen Ltd. | Method and apparatus for destroying dividing cells |
US6546290B1 (en) * | 2000-04-12 | 2003-04-08 | Roamitron Holding S.A. | Method and apparatus for electromedical therapy |
JP3493428B2 (ja) * | 2000-07-04 | 2004-02-03 | 新潟大学長 | 癌温熱治療装置 |
US20020198567A1 (en) * | 2001-06-07 | 2002-12-26 | Yona Keisari | Electro-endocytotic therapy as a treatment modality of cancer |
US6994706B2 (en) | 2001-08-13 | 2006-02-07 | Minnesota Medical Physics, Llc | Apparatus and method for treatment of benign prostatic hyperplasia |
US7344532B2 (en) | 2001-08-27 | 2008-03-18 | Gyrus Medical Limited | Electrosurgical generator and system |
AU2002360540A1 (en) * | 2001-12-04 | 2003-06-17 | University Of Southern California | Method for intracellular modifications within living cells using pulsed electric fields |
CA2563817C (en) | 2004-04-23 | 2018-07-10 | Yoram Palti | Treating a tumor or the like with electric fields at different frequencies |
DE102004028156A1 (de) * | 2004-06-09 | 2006-01-05 | Kalbe, Jochen, Dr. | Kombination von Radiowellen mit pharmakologisch aktiven Substanzen |
ATE463277T1 (de) | 2004-12-07 | 2010-04-15 | Standen Ltd | Elektroden zum anlegen eines elektrischen felds in vivo über einen längeren zeitraum |
EP1833554A2 (en) | 2004-12-27 | 2007-09-19 | Standen Ltd. | Treating a tumor or the like with electric fields at different orientations |
CN101287519B (zh) | 2005-06-08 | 2014-10-29 | 斯坦顿有限公司 | 利用被导引到身体内的期望位置的电场来治疗癌症的装置 |
JP2009520509A (ja) * | 2005-10-03 | 2009-05-28 | ノヴォキュアー・リミテッド | 増殖細胞における電場の効果を増大させるための電場の最適化特性 |
US8019414B2 (en) * | 2006-04-05 | 2011-09-13 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with other treatment regimens |
WO2009044289A1 (en) * | 2007-03-06 | 2009-04-09 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with photodynamic therapy |
US8715203B2 (en) * | 2007-09-17 | 2014-05-06 | Novocure Limited | Composite electrode |
-
2006
- 2006-09-29 JP JP2008534095A patent/JP2009520509A/ja active Pending
- 2006-09-29 PT PT202103990T patent/PT3804809T/pt unknown
- 2006-09-29 DK DK20210399.0T patent/DK3804809T3/da active
- 2006-09-29 CN CN202011309669.0A patent/CN112402798B/zh active Active
- 2006-09-29 ES ES06820767.9T patent/ES2534488T3/es active Active
- 2006-09-29 CA CA2624624A patent/CA2624624C/en active Active
- 2006-09-29 EP EP15151025.2A patent/EP2902075B1/en active Active
- 2006-09-29 US US11/537,026 patent/US7917227B2/en active Active
- 2006-09-29 WO PCT/IB2006/002713 patent/WO2007039799A2/en active Application Filing
- 2006-09-29 EP EP06820767.9A patent/EP1933937B1/en active Active
- 2006-09-29 EP EP20210399.0A patent/EP3804809B1/en active Active
- 2006-09-29 CN CN200680043421.6A patent/CN101321555B/zh active Active
- 2006-09-29 CN CN201510091454.9A patent/CN104771830B/zh active Active
- 2006-09-29 DK DK06820767T patent/DK1933937T3/da active
- 2006-09-29 PT PT68207679T patent/PT1933937E/pt unknown
-
2010
- 2010-08-06 US US12/851,761 patent/US8718756B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2007039799A2 (en) | 2007-04-12 |
CN104771830B (zh) | 2018-10-26 |
US8718756B2 (en) | 2014-05-06 |
CN101321555B (zh) | 2020-12-08 |
EP3804809A1 (en) | 2021-04-14 |
US20100324547A1 (en) | 2010-12-23 |
CA2624624C (en) | 2016-07-19 |
CN112402798A (zh) | 2021-02-26 |
JP2009520509A (ja) | 2009-05-28 |
CA2624624A1 (en) | 2007-04-12 |
US20070225766A1 (en) | 2007-09-27 |
EP3804809B1 (en) | 2023-12-27 |
PT3804809T (pt) | 2024-03-07 |
EP2902075A1 (en) | 2015-08-05 |
DK1933937T3 (da) | 2015-04-07 |
WO2007039799A3 (en) | 2007-07-12 |
PT1933937E (pt) | 2015-04-23 |
ES2534488T3 (es) | 2015-04-23 |
CN112402798B (zh) | 2021-11-16 |
EP2902075B1 (en) | 2022-11-16 |
EP1933937B1 (en) | 2015-01-14 |
CN101321555A (zh) | 2008-12-10 |
CN104771830A (zh) | 2015-07-15 |
EP1933937A2 (en) | 2008-06-25 |
US7917227B2 (en) | 2011-03-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3804809T3 (da) | Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler | |
DE112005001370T5 (de) | Verzweigte Biodiesel | |
BRPI0906077A2 (pt) | "conjunto de cécula fotovoltaica" | |
DE602006007508D1 (de) | Multi-Staubsammler | |
DK1880574T3 (da) | Høresystem med forbedret højfrekvensrespons | |
MX2008006599A (es) | Preparacion con edulcorante de alta potencia | |
DK2015430T3 (da) | Forbedringer af rørformede elektriske generatorer | |
DE502006004466D1 (de) | Elektrisches bauelement | |
DE502005004462D1 (de) | Flügelglätter | |
ITMI20051723A1 (it) | Struttura elettrica riscaldante | |
DE602007000677D1 (de) | Konstantstromschaltung | |
DE112006001884A5 (de) | Elektrisches Bauelement | |
FI20060759A (fi) | Rinnankytkettyjen taajuusmuuttajien tehotasapaino | |
DE102006000112A8 (de) | Separatoreinheit | |
DK2033487T3 (da) | Høreapparat med et forlænget element | |
DE602005025024D1 (de) | Referenzspannungs-erzeugungsschaltung | |
DE112006003688A5 (de) | Abdeckung von Solarzellen | |
DE602005016287D1 (de) | Konstantspannungs-erzeugungsschaltung | |
DE112006003697A5 (de) | Solarkollektor | |
DK1786010T3 (da) | Elektrisk koblingsanlæg | |
SE0500674L (sv) | Kombinerad kollektor | |
SE0401280L (sv) | Elanslutningar | |
FR2876232B3 (fr) | Convertisseur-thermo-electrique solaire | |
DE602007002925D1 (de) | Getaktete Leistungsschaltung | |
DE502007003818D1 (de) | Elektrohandschleifmaschine |