ATE463277T1 - Elektroden zum anlegen eines elektrischen felds in vivo über einen längeren zeitraum - Google Patents

Elektroden zum anlegen eines elektrischen felds in vivo über einen längeren zeitraum

Info

Publication number
ATE463277T1
ATE463277T1 AT05826419T AT05826419T ATE463277T1 AT E463277 T1 ATE463277 T1 AT E463277T1 AT 05826419 T AT05826419 T AT 05826419T AT 05826419 T AT05826419 T AT 05826419T AT E463277 T1 ATE463277 T1 AT E463277T1
Authority
AT
Austria
Prior art keywords
patient
electrode
electrodes
applying
longer period
Prior art date
Application number
AT05826419T
Other languages
English (en)
Inventor
Yoram Palti
Original Assignee
Standen Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36096350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE463277(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
US case filed in Florida Middle District Court litigation https://portal.unifiedpatents.com/litigation/Florida%20Middle%20District%20Court/case/8%3A22-cv-02535 Source: District Court Jurisdiction: Florida Middle District Court "Unified Patents Litigation Data" by Unified Patents is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Standen Ltd filed Critical Standen Ltd
Application granted granted Critical
Publication of ATE463277T1 publication Critical patent/ATE463277T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0452—Specially adapted for transcutaneous muscle stimulation [TMS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/046—Specially adapted for shock therapy, e.g. defibrillation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05826419T 2004-12-07 2005-12-05 Elektroden zum anlegen eines elektrischen felds in vivo über einen längeren zeitraum ATE463277T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63387104P 2004-12-07 2004-12-07
PCT/IB2005/003670 WO2006061688A1 (en) 2004-12-07 2005-12-05 Electrodes for applying an electric field in-vivo over an extended period of time

Publications (1)

Publication Number Publication Date
ATE463277T1 true ATE463277T1 (de) 2010-04-15

Family

ID=36096350

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05826419T ATE463277T1 (de) 2004-12-07 2005-12-05 Elektroden zum anlegen eines elektrischen felds in vivo über einen längeren zeitraum

Country Status (11)

Country Link
US (2) US7715921B2 (de)
EP (5) EP2364747B1 (de)
JP (2) JP5260056B2 (de)
CN (2) CN102389618B (de)
AT (1) ATE463277T1 (de)
CA (1) CA2590342C (de)
DE (1) DE602005020504D1 (de)
DK (5) DK1833552T3 (de)
ES (5) ES2344215T3 (de)
PT (5) PT1833552E (de)
WO (1) WO2006061688A1 (de)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2335776A1 (de) 2000-02-17 2011-06-22 Yoram Palti Verfahren und vorrichtung zur zerstörung von teilenden zellen
US7890183B2 (en) * 2000-02-17 2011-02-15 Novocure Ltd. Treating parasites with electric fields
US8447395B2 (en) * 2000-02-17 2013-05-21 Novocure Ltd Treating bacteria with electric fields
US7136699B2 (en) * 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US7089054B2 (en) * 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
US8175698B2 (en) 2000-02-17 2012-05-08 Novocure Ltd. Treating bacteria with electric fields
US7599746B2 (en) 2000-02-17 2009-10-06 Standen Ltd Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases
US9962538B2 (en) * 2003-02-06 2018-05-08 Axelgaard Manufacturing Company, Ltd. Multi-electrode with lateral conductivity control
WO2005115535A2 (en) 2004-04-23 2005-12-08 Novocure Ltd. Treating a tumor or the like with electric fields at different frequencies
JP4950055B2 (ja) * 2004-10-19 2012-06-13 メーガン メディカル インコーポレイティッド 皮膚感覚受容器の電気刺激のための方法および手段
US8417352B2 (en) * 2004-10-19 2013-04-09 Meagan Medical, Inc. System and method for stimulating sensory nerves
DK1833552T3 (da) * 2004-12-07 2010-08-02 Standen Ltd Elektroder til anbringelse af et elektrisk felt in-vivo i en længere tidsperiode
CN102488967B (zh) * 2004-12-27 2016-03-30 诺沃库勒有限公司 利用电场从不同方向治疗肿瘤等
DK3804809T3 (da) * 2005-10-03 2024-02-12 Novocure Gmbh Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler
US8874227B2 (en) 2009-03-20 2014-10-28 ElectroCore, LLC Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient
US7744591B2 (en) * 2005-12-29 2010-06-29 Boston Scientific Scimed, Inc. Foam electrode and method of use thereof during tissue resection
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
WO2007088395A1 (en) * 2006-02-03 2007-08-09 Bae Systems Plc Improvements relating to damage sensors
US8019414B2 (en) 2006-04-05 2011-09-13 Novocure Ltd. Treating cancer using electromagnetic fields in combination with other treatment regimens
CN101553180B (zh) * 2006-09-14 2013-08-07 拉热尔技术有限公司 用于破坏癌细胞的装置
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
DK2167194T3 (en) * 2007-03-06 2017-06-19 Novocure Ltd TREATMENT OF CANCER USING ELECTROMAGNETIC FIELDS IN COMBINATION WITH PHOTODYNAMIC THERAPY
US8562602B2 (en) * 2007-09-14 2013-10-22 Lazure Technologies, Llc Multi-layer electrode ablation probe and related methods
CN105232148A (zh) 2007-09-14 2016-01-13 拉热尔技术有限公司 前列腺癌消融
WO2009036459A1 (en) * 2007-09-14 2009-03-19 Lazure Technologies, Llc Multi-tine probe and treatment by activation of opposing tines
EP2082777A1 (de) * 2008-01-27 2009-07-29 Oncotherm Kft. Flexible, poröse, großflächige Elektrode zum Heizen
US8515532B2 (en) * 2008-08-29 2013-08-20 Koninklijke Philips N.V. Compensation of motion artifacts in capacitive measurement of electrophysiological signals
US20100100093A1 (en) * 2008-09-16 2010-04-22 Lazure Technologies, Llc. System and method for controlled tissue heating for destruction of cancerous cells
US8805517B2 (en) * 2008-12-11 2014-08-12 Nokia Corporation Apparatus for providing nerve stimulation and related methods
US8728139B2 (en) 2009-04-16 2014-05-20 Lazure Technologies, Llc System and method for energy delivery to a tissue using an electrode array
US8779307B2 (en) 2009-10-05 2014-07-15 Nokia Corporation Generating perceptible touch stimulus
AU2010313487A1 (en) 2009-10-26 2012-05-24 Emkinetics, Inc. Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
US9526911B1 (en) 2010-04-27 2016-12-27 Lazure Scientific, Inc. Immune mediated cancer cell destruction, systems and methods
US8791800B2 (en) 2010-05-12 2014-07-29 Nokia Corporation Detecting touch input and generating perceptible touch stimulus
US9579690B2 (en) 2010-05-20 2017-02-28 Nokia Technologies Oy Generating perceptible touch stimulus
US8473072B2 (en) * 2010-06-08 2013-06-25 Axelgaard Manufacturing Company, Ltd. Customizable medical electrode
US9110507B2 (en) 2010-08-13 2015-08-18 Nokia Technologies Oy Generating perceptible touch stimulus
KR101030082B1 (ko) * 2010-09-10 2011-04-19 한국기계연구원 전기장 처치기 및 그 제조 방법
EP2618890A4 (de) * 2010-09-20 2014-03-26 Emkinetics Inc Verfahren und vorrichtung zur transkutanen stimulation über den handflächen und fusssohlen
US9233257B1 (en) 2010-11-22 2016-01-12 Jacob Zabara Electromagnetic radiation treatment
US8684901B1 (en) 2010-11-22 2014-04-01 Jacob Zabara Electromagnetic radiation treatment for cancer and pathological genetic regulations
CA2826770C (en) 2011-02-15 2020-06-23 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
WO2013022939A1 (en) 2011-08-08 2013-02-14 Ruse Richard B Method and apparatus for treating cancer
US9486625B2 (en) 2011-08-08 2016-11-08 Medamp Electronics, Llc Method for treating benign prostate hyperplasia
WO2014039569A2 (en) 2012-09-05 2014-03-13 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
WO2014056090A1 (en) * 2012-10-11 2014-04-17 Sunnybrook Research Institute Electrode designs for efficient neural stimulation
US9161802B2 (en) 2013-01-03 2015-10-20 Solta Medical, Inc. Patterned electrodes for tissue treatment systems
US9962546B2 (en) 2013-02-21 2018-05-08 Meagan Medical, Inc. Cutaneous field stimulation with disposable and rechargeable components
US8880196B2 (en) * 2013-03-04 2014-11-04 Zoll Medical Corporation Flexible therapy electrode
KR101297791B1 (ko) * 2013-03-22 2013-08-19 이기세 피부미용장치의 팁 구조
US10779875B2 (en) 2013-05-06 2020-09-22 Novocure Gmbh Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
US9655669B2 (en) 2013-05-06 2017-05-23 Novocure Limited Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
US20190117963A1 (en) * 2014-07-25 2019-04-25 Loyalty Based Innovations, LLC Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
GB201511205D0 (en) * 2015-06-25 2015-08-12 Sky Medical Technology Ltd Multiple negative electrodes
US10188851B2 (en) 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US10821283B2 (en) 2016-04-04 2020-11-03 Novocure Gmbh Reducing motility of cancer cells using tumor treating fields (TTFields)
EP3478360B1 (de) 2016-06-30 2024-04-10 Novocure GmbH Anordnungen zur longitudinalen abgabe von tumortherapiefeldern an einen körper
EP3571503B1 (de) 2017-01-19 2026-04-15 Novocure GmbH System zur betrachtung von zellkulturen unter einem mikroskop bei gleichzeitiger anwendung von ttfields
US12649056B2 (en) 2017-10-23 2026-06-09 Cardiac Pacemakers, Inc. Medical devices for treatment of cancer with electric fields
US11338135B2 (en) * 2017-10-23 2022-05-24 Cardiac Pacemakers, Inc. Medical devices for cancer therapy with electric field shaping elements
US12403306B2 (en) 2017-10-23 2025-09-02 Cardiac Pacemakers, Inc. Electric field shaping leads for treatment of cancer
CN110115803A (zh) * 2018-02-07 2019-08-13 张建义 一种可用于生物医学研究的电源装置及配套电极阵列设计
US10953209B2 (en) 2018-03-28 2021-03-23 Board Of Regents Of The University Of Texas System Treating tumors using TTFields combined with a PARP inhibitor
CN112566665A (zh) 2018-04-09 2021-03-26 莫舍·吉拉迪 用TTFields和Aurora激酶抑制剂治疗肿瘤
US11650277B2 (en) 2018-04-10 2023-05-16 Novocure Gmbh TTField treatment with optimization of electrode positions based on low frequency (<1MHZ) AC conductivity estimates derived from two MRI images having different repetition times
CN112135661B (zh) 2018-05-21 2024-11-19 深江技术有限责任公司 低频电刺激装置用防水壳体、防水型低频电刺激装置和低频电刺激用绝缘体电极
KR102104961B1 (ko) * 2018-07-03 2020-04-27 고려대학교산학협력단 최적화 알고리즘을 이용한 전기장 암치료장치
KR102870236B1 (ko) 2018-07-03 2025-10-14 에드윈 창 세포막 투과성을 향상시키기 위한 교류 전기장 사용
US11179322B2 (en) 2018-07-10 2021-11-23 Novocure Gmbh Methods and compositions for treating tumors with TTFields and sorafenib
NZ770868A (en) 2018-07-10 2023-12-22 Novocure Gmbh Inhibiting viral infection using alternating electric fields
IL279253B2 (en) 2018-07-18 2025-09-01 Novocure Gmbh Using power loss density and related measurements to quantify dose of tumor treatment fields
MX2020013519A (es) 2018-08-23 2021-05-12 Novocure Gmbh Uso de campos electricos alternativos para aumentar la permeabilidad de la barrera hematoencefalica.
US11160977B2 (en) 2018-09-04 2021-11-02 Novocure Gmbh Delivering tumor treating fields (TTFields) to the infratentorial brain
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
US11020585B2 (en) 2018-09-07 2021-06-01 Novocure Gmbh Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells
HUE061361T2 (hu) 2018-10-15 2023-06-28 Novocure Gmbh Az egész agyban nagy egyenletességû tumorkezelõ mezõk (TT-mezõk) generálása
CN112955208B (zh) 2018-10-25 2024-11-22 诺沃库勒有限责任公司 向受试者的脊柱解剖结构递送交变电场(例如,ttfields)的方法
CN113286628A (zh) * 2018-11-01 2021-08-20 诚为本创新有限责任公司 通过电场治疗具有转移性疾病的患者中的多个肿瘤的设备和方法
US12186575B2 (en) 2018-11-13 2025-01-07 The Methodist Hospital Method and apparatus for oncomagnetic treatment
HUE065574T2 (hu) 2018-11-19 2024-06-28 Novocure Gmbh Tömbök daganatkezelõ mezõk (TTFIELD) rendelkezésre bocsátására szelektíven címezhetõ alelemekkel
JP7353363B2 (ja) 2018-11-29 2023-09-29 ノボキュア ゲーエムベーハー TTFields(腫瘍治療電場)を提供するための柔軟性を高めたトランスデューサーアレイ
EP3968279B1 (de) 2019-01-08 2025-01-01 Novocure GmbH Bewertung der qualität der segmentierung eines bildes in verschiedene gewebearten zur planung der behandlung mit tumorbehandlungsfeldern (ttfields)
WO2020174403A1 (en) 2019-02-26 2020-09-03 Moshe Giladi Determining a frequency for ttfields treatment based on an electrical characteristic of targeted cancer cells
EP4491214B1 (de) 2019-02-27 2026-01-21 Novocure GmbH Abgabe von tumorbehandlungsfeldern (ttfields) unter verwendung implantierbarer wandlerarrays
PL3946322T3 (pl) 2019-03-29 2024-02-26 Novocure Gmbh Sposoby przywracania wrażliwości na ttfields w komórkach nowotworowych opornych wobec ttfields, z inhibitorami ptger3
CN111803792A (zh) * 2019-04-12 2020-10-23 上海必修福企业管理有限公司 空间电场的发生装置
WO2020212824A1 (en) 2019-04-17 2020-10-22 Yoram Wasserman Uploading data from an isolated system without compromising isolation
CN113766949B (zh) 2019-04-22 2025-04-08 波士顿科学国际有限公司 用于施用电刺激以治疗癌症的系统
JP7593942B2 (ja) 2019-04-22 2024-12-03 ボストン サイエンティフィック サイムド,インコーポレイテッド 癌治療のための電気刺激機器
US12109412B2 (en) 2019-04-22 2024-10-08 Boston Scientific Scimed, Inc. Combination electrical and chemotherapeutic treatment of cancer
JP2022529374A (ja) 2019-04-23 2022-06-21 ボストン サイエンティフィック サイムド,インコーポレイテッド がん治療のための電気刺激用電極
WO2020219521A1 (en) 2019-04-23 2020-10-29 Boston Scientific Scimed, Inc. Electrical stimulation with thermal treatment or thermal monitoring
US11607542B2 (en) 2019-04-23 2023-03-21 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes
CN121314073A (zh) 2019-07-31 2026-01-13 诺沃库勒有限责任公司 经由埋入颅骨植入物中的电极施加肿瘤治疗场(TTField)
CN114390914A (zh) 2019-08-05 2022-04-22 诺沃库勒有限责任公司 通过抑制il11活性增加癌细胞对肿瘤治疗场(ttfield)的敏感性
US11890467B2 (en) 2019-08-30 2024-02-06 Novocure Gmbh Delivering tumor treating fields (TTFields) to the neck
WO2021092402A1 (en) 2019-11-08 2021-05-14 Novocure Gmbh Perforated hydrogel configurations and methods of production and use thereof
CN115243617B (zh) 2019-12-23 2025-10-28 测验有限公司 电极贴片和连接系统
KR20220122679A (ko) 2019-12-31 2022-09-02 노보큐어 게엠베하 채널들의 스위칭 및 진폭 조정 중 스파이크들을 방지하는 고전압, 고효율 사인파 생성기
HUE061733T2 (hu) 2019-12-31 2023-08-28 Novocure Gmbh Tömbök tumorkezelõ mezõk (TTFields) szállítására egyenként hozzáférhetõ elektródaelemekkel és hõmérsékletérzékelõkkel
US12121739B2 (en) * 2019-12-31 2024-10-22 Novocure Gmbh Methods, systems, and apparatuses for managing temperatures induced by alternating fields
US11883655B2 (en) 2020-02-24 2024-01-30 Boston Scientific Scimed, Inc. Systems and methods for treatment of pancreatic cancer
US20210299440A1 (en) 2020-03-30 2021-09-30 Novocure Gmbh Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases
CN115916325A (zh) 2020-04-24 2023-04-04 诺沃库勒有限责任公司 使用交变电场增加血脑屏障的通透性
KR102464313B1 (ko) 2020-05-18 2022-11-08 주식회사 필드큐어 전기장 암 치료 시스템을 위한 품질 보증 장치 및 방법
WO2021257967A1 (en) 2020-06-19 2021-12-23 The Methodist Hospital Dba Houston Methodist Hospital Method and apparatus for oncomagnetic treatment
US11818943B2 (en) 2020-06-25 2023-11-14 Novocure Gmbh Fabricating organic light emitting diodes (OLEDs) using tubulin
EP4567054B1 (de) 2020-06-30 2025-12-17 Novocure GmbH Flexible wandlerarrays mit einer polymerisolationsschicht zur anwendung von tumorbehandlungsfeldern (ttfields)
WO2022018615A1 (en) * 2020-07-21 2022-01-27 Palti Yoram Prof Apparatus for strengthening muscle contraction (e.g., cardiac muscle contraction) using electric fields
CN120393288A (zh) * 2020-08-28 2025-08-01 江苏海莱新创医疗科技有限公司 可穿戴电场施加装置
EP4223363B1 (de) 2020-09-25 2024-04-24 Novocure GmbH Variation des metallisierungsbereichs auf einzelnen elektrodenelementen in einem tumorbehandlungsfeldsystem zur strommaximierung ohne überhitzung
WO2022130183A2 (en) * 2020-12-17 2022-06-23 Novocure Gmbh Pyroelectric-based temperature sensing of transducer arrays for applying tumor treating fields (ttfields)
CN112774024B (zh) * 2020-12-29 2025-08-05 江苏海莱新创医疗科技有限公司 一种应用于人体皮肤有吸湿结构的电极垫
CN112755385A (zh) * 2021-01-26 2021-05-07 江苏海莱新创医疗科技有限公司 一种用于缺损颅骨的电极
JP7844490B2 (ja) 2021-02-17 2026-04-13 ノボキュア ゲーエムベーハー 個別に調節可能な活性領域を有する電極素子のセットで腫瘍治療電場(TTFields)を送達するためのアレイ
JP2024509964A (ja) 2021-03-12 2024-03-05 ノボキュア ゲーエムベーハー 交流電界を用いてマクロファージの表現型をスキューイングすることによる、疾患を処置する方法
US12589255B2 (en) * 2021-03-23 2026-03-31 Novocure Gmbh Methods and apparatuses for detecting and responding to changes in a subject
CN117120139A (zh) 2021-03-31 2023-11-24 诺沃库勒有限责任公司 使用肿瘤治疗场(ttfield)系统的电极的阻抗断层摄影
WO2022215051A1 (en) 2021-04-08 2022-10-13 Novocure Gmbh Methods of treating neurodegenerative disorders with alternating electric fields
MX2023014225A (es) 2021-06-30 2024-01-24 Novocure Gmbh Uso de condensadores para regular la corriente en matrices de transductores para aplicar campos de tratamiento de tumores (ttfields).
US12409332B2 (en) 2021-08-12 2025-09-09 Novocure Gmbh Methods and apparatuses for delivering tumor treating fields to a subject's body for near-surface tumors
US12263339B2 (en) * 2021-08-12 2025-04-01 Novocure Gmbh Apparatuses for delivering tumor treating fields having electrode elements with nonuniform thicknesses and methods for manufacturing same
US20230066875A1 (en) * 2021-08-12 2023-03-02 Novocure Gmbh Transducer apparatuses with electrode array shaped to reduce edge effect in delivering tumor treating fields to a subject's body
JP2024528845A (ja) * 2021-08-12 2024-08-01 ノボキュア ゲーエムベーハー 腫瘍治療電場を被験者の身体に送達する際にエッジ効果を減らすための電極素子を備えたトランスデューサ装置
US11877838B2 (en) * 2021-08-14 2024-01-23 Nano Hesgarsazan Salamat Arya Preventing cytokine storm in COVID-19 patients by suppressing clonal expansion in activated lymphocytes using alternating electric fields
CN113749762B (zh) * 2021-08-27 2022-06-17 江苏海莱新创医疗科技有限公司 高散热性能电极
US20230116844A1 (en) * 2021-09-27 2023-04-13 Novocure Gmbh Compositions and methods for testing adverse skin events
CN114099960B (zh) * 2021-12-22 2023-01-24 江苏海莱新创医疗科技有限公司 肿瘤电场治疗系统及其电极贴片
CN114272513A (zh) * 2021-12-22 2022-04-05 杭州海莱新创医疗科技有限公司 肿瘤电场治疗系统及其电极片
CN114099958B (zh) * 2021-12-22 2023-10-13 江苏海莱新创医疗科技有限公司 电场治疗仪及其电极贴片
CN114306930A (zh) * 2021-12-22 2022-04-12 杭州海莱新创医疗科技有限公司 肿瘤电场治疗系统及其电极片
CN114099954B (zh) * 2021-12-22 2023-06-06 江苏海莱新创医疗科技有限公司 电场治疗仪及其电极贴片
ES3072891T3 (en) * 2021-09-30 2026-07-06 Novocure Gmbh Method and system for applying tumor treating fields interfacing with hair follicles
KR102568337B1 (ko) 2021-09-30 2023-08-21 주식회사 필드큐어 전극 시스템의 최적화 방법
KR102650606B1 (ko) * 2021-10-15 2024-03-21 가톨릭대학교 산학협력단 암치료용 전류 공급 방법 및 장치
IL312074A (en) 2021-12-14 2024-06-01 Novocure Gmbh Moving a transducer array to reduce skin irritation
CN121422385B (zh) * 2021-12-22 2026-07-17 江苏海莱新创医疗科技有限公司 肝癌治疗系统
TW202333820A (zh) 2021-12-29 2023-09-01 瑞士商諾沃庫勒有限責任公司 在使用交流電場治療受試者時藉由使用較大陰極和較小陽極來降低電知覺
EP4456971A1 (de) 2021-12-30 2024-11-06 Novocure GmbH Auswahl von parameterwerten zur behandlung mit tumorbehandlungsfeldern (ttfields)
IL314390A (en) 2022-03-30 2024-09-01 Novocure Gmbh Using interleaved cooling periods to increase the peak intensity of tumor treating fields
EP4464370B1 (de) 2022-03-30 2026-04-29 Novocure GmbH Reduzierung der elektrosensierung bei der behandlung einer person unter verwendung von elektrischen wechselfeldern durch paarung von wandlerarrays
CA3254955A1 (en) * 2022-03-31 2023-10-05 Novocure Gmbh Electrode assembly having a perforated anisotropic layer, and systems and methods for applying tumor treatment fields using it
WO2023193012A2 (en) 2022-04-01 2023-10-05 The Board Of Regents Of The University Of Texas System Methods and apparatus for applying tumor treating fields combined with personalized ultra-fractionated stereotactic adaptive radiotherapy
TW202417078A (zh) 2022-06-30 2024-05-01 瑞士商諾沃庫勒有限責任公司 用於施加腫瘤治療電場的包括多個熱連接但電隔離的石墨片之電極組裝件
CN115381550B (zh) * 2022-07-15 2025-11-11 重庆科杰医疗技术有限公司 非接触式高周波电场发生与构场结构及治疗装置
TW202430241A (zh) 2022-09-30 2024-08-01 瑞士商諾沃庫勒有限責任公司 在使用交流電場治療受試者時藉由控制上升特性來降低電知覺
US12649061B2 (en) 2022-12-29 2026-06-09 Novocure Gmbh Reducing electrosensation during application of alternating electric fields by ensuring that successive increases in amplitude occur during opposite phases of an AC waveform
US12268863B2 (en) 2023-02-06 2025-04-08 Novocure Gmbh Shiftable transducer array with anisotropic material layer
WO2024168033A1 (en) * 2023-02-08 2024-08-15 Henley Julian Devices and methods for hair growth acceleration
US12558538B2 (en) 2023-09-29 2026-02-24 Novocure Gmbh Using staggered changes in amplitude and frequency to ameliorate electrosensation during treatment with alternating electric fields
WO2025117604A1 (en) * 2023-12-01 2025-06-05 Hinge Health, Inc. Electrode interfaces for neuromodulation device and method for use
SE2450263A1 (en) 2024-03-07 2025-09-08 Force Oncology Ab Personalized electrodes

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR446660A (fr) 1911-09-02 1912-12-12 Gottlieb Schuettel Dispositif pour métiers continus à anneaux pour monter les curseurs sur les anneaux
US2130759A (en) * 1937-12-11 1938-09-20 E J Rose Mfg Company Of Califo Electrode for diathermy treatment
BE794566A (fr) 1972-01-28 1973-07-26 Esb Inc Regenerateur et stimulateur bioelectrochimique et procedes d'application in vivo d'energie electrique a des cellules et des tissus.
DE2314573C2 (de) * 1973-03-23 1986-12-18 Werner Dipl.-Ing. 8000 München Kraus Gerät zur Förderung von Heilungsprozessen
US3991770A (en) 1974-01-24 1976-11-16 Leveen Harry H Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation
US4016886A (en) 1974-11-26 1977-04-12 The United States Of America As Represented By The United States Energy Research And Development Administration Method for localizing heating in tumor tissue
US4121592A (en) 1975-08-04 1978-10-24 Critical Systems, Inc. Apparatus for heating tissue
US4140130A (en) * 1977-05-31 1979-02-20 Storm Iii Frederick K Electrode structure for radio frequency localized heating of tumor bearing tissue
JPS5547870A (en) 1978-02-24 1980-04-05 Lawrence Joseph L Medical treatment method
DE2813068A1 (de) 1978-03-25 1979-10-04 Philips Patentverwaltung Verfahren und vorrichtung zur ermittlung von inneren koerperstrukturen
US4367755A (en) 1979-01-31 1983-01-11 Stimtech, Inc. Stimulating electrode
GB2043453A (en) 1979-02-22 1980-10-08 Electrochem Tech Corp Improvements in or relating to an electrode
US4472952A (en) * 1980-06-23 1984-09-25 Hollowell Jr Robert L System for managing the issuance and return of selected articles such as tools, keys and the like
US4472506A (en) 1981-01-13 1984-09-18 Liburdy Robert P Method for determining cell membrane dielectric breakdown
US4467809A (en) 1982-09-17 1984-08-28 Biolectron, Inc. Method for non-invasive electrical stimulation of epiphyseal plate growth
US4622952A (en) 1983-01-13 1986-11-18 Gordon Robert T Cancer treatment method
CA1244889A (en) 1983-01-24 1988-11-15 Kureha Chemical Ind Co Ltd HYPERTHERMIA DEVICE
DE3323415C2 (de) 1983-06-29 1985-04-25 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verwendung eines Verfahrens und einer Vorrichtung zur Bestimmung von Zellinhaltstoffe sezernierenden Zellen
SE455920B (sv) 1986-01-29 1988-08-22 Hans Wiksell Anordning for hypertermibehandling av tumorer
US4923814A (en) 1986-05-09 1990-05-08 Electropore, Inc. High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor
CN86103803B (zh) 1986-06-05 1987-11-18 北京信息工程学院 静电场治疗装置
US4837049A (en) * 1986-06-17 1989-06-06 Alfred E. Mann Foundation For Scientific Research Method of making an electrode array
US4822470A (en) 1987-10-09 1989-04-18 Baylor College Of Medicine Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses
US4936303A (en) 1987-11-20 1990-06-26 Ultrathermics Ultrasonic heating apparatus and method
JPH0629196B2 (ja) 1987-12-01 1994-04-20 甲子郎 梅村 超音波による腫瘍治療用生理作用増強剤
US5389069A (en) 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
FR2627987B3 (fr) 1988-03-04 1990-02-02 Indiba Sa Appareil electronique pour la therapie medicale et cosmetique
US4926879A (en) * 1988-06-13 1990-05-22 Sevrain-Tech, Inc. Electro-tactile stimulator
US5158071A (en) 1988-07-01 1992-10-27 Hitachi, Ltd. Ultrasonic apparatus for therapeutical use
GB8904998D0 (en) 1989-03-04 1989-04-19 Matthews Tony Anaesthetising apparatus
US5099756A (en) 1989-06-01 1992-03-31 Harry H. Leveen Radio frequency thermotherapy
US5441746A (en) 1989-12-22 1995-08-15 Molecular Bioquest, Inc. Electromagnetic wave absorbing, surface modified magnetic particles for use in medical applications, and their method of production
US5236410A (en) 1990-08-02 1993-08-17 Ferrotherm International, Inc. Tumor treatment method
WO1992019286A1 (en) 1991-05-03 1992-11-12 University Technologies International, Inc. Biofilm reduction method
US5441532A (en) 1991-06-26 1995-08-15 Massachusetts Institute Of Technology Adaptive focusing and nulling hyperthermia annular and monopole phased array applicators
US5468223A (en) 1992-11-30 1995-11-21 C.N.R.S. Paris Electrochemotherapy
US5386837A (en) 1993-02-01 1995-02-07 Mmtc, Inc. Method for enhancing delivery of chemotherapy employing high-frequency force fields
FR2703253B1 (fr) 1993-03-30 1995-06-23 Centre Nat Rech Scient Applicateur d'impulsions electriques pour traitement de tissus biologiques.
IL108775A (en) 1994-02-25 2003-09-17 Univ Ramot Method for efficient incorporation of molecules into cells
US5704355A (en) 1994-07-01 1998-01-06 Bridges; Jack E. Non-invasive system for breast cancer detection
US6447499B2 (en) 1995-07-28 2002-09-10 James R. Gray Use of a polarized field to modify the efficacy of a bioactive agent
US5606971A (en) 1995-11-13 1997-03-04 Artann Corporation, A Nj Corp. Method and device for shear wave elasticity imaging
US5718246A (en) 1996-01-03 1998-02-17 Preferential, Inc. Preferential induction of electrically mediated cell death from applied pulses
JPH09313618A (ja) * 1996-06-03 1997-12-09 Masaaki Kuribayashi 医療用電極の配置装置
US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US5984882A (en) 1996-08-19 1999-11-16 Angiosonics Inc. Methods for prevention and treatment of cancer and other proliferative diseases with ultrasonic energy
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US5848966A (en) * 1997-03-04 1998-12-15 Graphic Controls Corporation Medical device easily removed from skin and a method of removal therefrom
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
WO1999011771A1 (en) 1997-09-04 1999-03-11 Science Research Laboratory, Inc. Cell separation using electric fields
US5974344A (en) * 1998-03-02 1999-10-26 Shoemaker, Ii; Charles Wound care electrode
US6027488A (en) 1998-06-03 2000-02-22 Genetronics, Inc. Flow-through electroporation system for ex vivo gene therapy
US5976092A (en) 1998-06-15 1999-11-02 Chinn; Douglas O. Combination stereotactic surgical guide and ultrasonic probe
US6319901B1 (en) 1998-10-15 2001-11-20 Ichor Medical Systems, Inc. Methods for prolonging cell membrane permeability
ES2240078T3 (es) 1999-03-09 2005-10-16 Thermage, Inc. Aparato para el tratamiento de tejidos.
US6678558B1 (en) 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US6366808B1 (en) 2000-03-13 2002-04-02 Edward A. Schroeppel Implantable device and method for the electrical treatment of cancer
US6853864B2 (en) 2000-02-02 2005-02-08 Catholic University Of America, The Use of electromagnetic fields in cancer and other therapies
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
US7146210B2 (en) 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US8175698B2 (en) 2000-02-17 2012-05-08 Novocure Ltd. Treating bacteria with electric fields
US6868289B2 (en) 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
US7890183B2 (en) 2000-02-17 2011-02-15 Novocure Ltd. Treating parasites with electric fields
US7136699B2 (en) 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US7089054B2 (en) 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
EP2335776A1 (de) 2000-02-17 2011-06-22 Yoram Palti Verfahren und vorrichtung zur zerstörung von teilenden zellen
US7599746B2 (en) 2000-02-17 2009-10-06 Standen Ltd Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases
US6546290B1 (en) 2000-04-12 2003-04-08 Roamitron Holding S.A. Method and apparatus for electromedical therapy
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US6694193B2 (en) * 2001-09-14 2004-02-17 Koninklijke Philips Electronics N.V. Medical electrode and release liner configurations facilitating packaged electrode characterization
US7043308B2 (en) * 2003-02-19 2006-05-09 Stimu-Heal, Inc. Surface electrode for electrical stimulation of tissue
WO2005115535A2 (en) 2004-04-23 2005-12-08 Novocure Ltd. Treating a tumor or the like with electric fields at different frequencies
US7463917B2 (en) * 2004-04-28 2008-12-09 Medtronic, Inc. Electrodes for sustained delivery of energy
DE102004028156A1 (de) 2004-06-09 2006-01-05 Kalbe, Jochen, Dr. Kombination von Radiowellen mit pharmakologisch aktiven Substanzen
DK1833552T3 (da) 2004-12-07 2010-08-02 Standen Ltd Elektroder til anbringelse af et elektrisk felt in-vivo i en længere tidsperiode
CN102488967B (zh) 2004-12-27 2016-03-30 诺沃库勒有限公司 利用电场从不同方向治疗肿瘤等
DK1899001T3 (en) 2005-06-08 2017-12-04 Novocure Ltd DEVICE FOR CANCER TREATMENT WITH ELECTRIC FIELDS MADE FOR DESIRED LOCATIONS IN A BODY
DK3804809T3 (da) 2005-10-03 2024-02-12 Novocure Gmbh Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler
US8019414B2 (en) 2006-04-05 2011-09-13 Novocure Ltd. Treating cancer using electromagnetic fields in combination with other treatment regimens
DK2167194T3 (en) 2007-03-06 2017-06-19 Novocure Ltd TREATMENT OF CANCER USING ELECTROMAGNETIC FIELDS IN COMBINATION WITH PHOTODYNAMIC THERAPY
US8715203B2 (en) 2007-09-17 2014-05-06 Novocure Limited Composite electrode

Also Published As

Publication number Publication date
US7715921B2 (en) 2010-05-11
JP5653954B2 (ja) 2015-01-14
JP2012143590A (ja) 2012-08-02
CA2590342A1 (en) 2006-06-15
JP5260056B2 (ja) 2013-08-14
ES2563282T3 (es) 2016-03-14
EP1833552A1 (de) 2007-09-19
EP2161054A1 (de) 2010-03-10
US20100179621A1 (en) 2010-07-15
CN101115522A (zh) 2008-01-30
EP2364747B1 (de) 2018-01-24
EP2364748A1 (de) 2011-09-14
DK2364748T3 (en) 2018-03-19
PT1833552E (pt) 2010-07-13
ES2663782T3 (es) 2018-04-17
PT2161054E (pt) 2016-02-16
EP2345451A1 (de) 2011-07-20
WO2006061688A1 (en) 2006-06-15
EP2364748B1 (de) 2018-01-24
CA2590342C (en) 2016-09-20
DK1833552T3 (da) 2010-08-02
PT2364748T (pt) 2018-03-26
DK2345451T3 (en) 2018-04-23
CN101115522B (zh) 2012-05-09
CN102389618B (zh) 2015-01-28
PT2364747T (pt) 2018-04-20
HK1142019A1 (en) 2010-11-26
US20060149341A1 (en) 2006-07-06
EP2345451B1 (de) 2018-01-24
EP2161054B1 (de) 2015-12-02
DK2161054T3 (en) 2016-01-25
EP2364747A1 (de) 2011-09-14
CN102389618A (zh) 2012-03-28
ES2663779T3 (es) 2018-04-17
ES2344215T3 (es) 2010-08-20
PT2345451T (pt) 2018-04-19
EP1833552B1 (de) 2010-04-07
DK2364747T3 (en) 2018-04-30
ES2660829T3 (es) 2018-03-26
JP2008532564A (ja) 2008-08-21
DE602005020504D1 (de) 2010-05-20
US8170684B2 (en) 2012-05-01

Similar Documents

Publication Publication Date Title
DE602005020504D1 (de) Vivo über einen längeren zeitraum
WO2005023361A3 (en) Disposable electric bandage
DK1843814T3 (da) Anordning til transkutan stimulation af en nerve i det menneskelige legeme
ATE507870T1 (de) Transseptale/transmyokardiale ventrikuläre pacing-ableitung
WO2004073483A3 (en) Surface electrode for electrical stimulation of tissue
ATE539793T1 (de) Retina-implantat mit einem grundkörper
ATE494037T1 (de) Neurale elektrode
DE602006008525D1 (de) Dreidimensionale hermetisch versiegelte Elektrodenmatrix
RU2017113694A (ru) Орошаемый балонный катетер, имеющий электродный узел с гибкой схемой
WO2005016446A3 (en) An electrode array for use in medical stimulation and methods thereof
WO2007134288A3 (en) Electrode-battery assembly for tens device
NO20022310L (no) Volumspesifikk karakterisering av menneskehud ved elektrisk immitans
ATE531421T1 (de) Elektroden-leitungs-verbindung mit bildgebung nach der implantation
WO2011159923A3 (en) Implantable micro-component electrodes
BR0308438A (pt) Elétrodo biomédico e método para obter e transmitir sinais elétricos de origem eletrofisiológica ou eletrobiológica de um paciente
WO2003089059A3 (en) Subcutaneous cardiac stimulator device with small contact surface electrodes
SE0003341D0 (sv) A coating method
DK2229977T3 (da) Elektrode til kontinuert stimulering af en ansigtsnerverod og apparatur til overvågning af elektromyogrammer for ansigtsmuskler under anvendelse af denne elektrode
JP1770761S (ja) 腫瘍治療用の医療処置装置
TW200724185A (en) Face head pad for an iontophoresis device
DE502009000028D1 (de) Multipolarer Führungsdraht und Elektrodenleitung
ATE478701T1 (de) Vorrichtung zur elektrostimulation
ATE512491T1 (de) Vorrichtung zur behandlung der korona
SE0202448D0 (sv) Probe suitable for use in neural tissue
ATE308361T1 (de) In koronarvenen implantierbare leitung zur stimulation eines linken herzvorhofs