PL3984590T3 - Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu - Google Patents
Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózguInfo
- Publication number
- PL3984590T3 PL3984590T3 PL21205743.4T PL21205743T PL3984590T3 PL 3984590 T3 PL3984590 T3 PL 3984590T3 PL 21205743 T PL21205743 T PL 21205743T PL 3984590 T3 PL3984590 T3 PL 3984590T3
- Authority
- PL
- Poland
- Prior art keywords
- ttfields
- brain
- high uniformity
- uniformity throughout
- tumor treating
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 210000004556 brain Anatomy 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0492—Patch electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Databases & Information Systems (AREA)
- Urology & Nephrology (AREA)
- General Business, Economics & Management (AREA)
- Pathology (AREA)
- Business, Economics & Management (AREA)
- Data Mining & Analysis (AREA)
- Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Developmental Disabilities (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Social Psychology (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862745689P | 2018-10-15 | 2018-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3984590T3 true PL3984590T3 (pl) | 2023-05-02 |
Family
ID=68426548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21205743.4T PL3984590T3 (pl) | 2018-10-15 | 2019-10-11 | Wytwarzanie pól leczących guzy (pól elektrycznych do leczenia nowotworów ttfields) o wysokiej równomierności w całym mózgu |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US11154707B2 (pl) |
| EP (4) | EP3840823B1 (pl) |
| JP (2) | JP7284886B2 (pl) |
| CN (3) | CN118925056A (pl) |
| HU (1) | HUE061361T2 (pl) |
| PL (1) | PL3984590T3 (pl) |
| WO (1) | WO2020079554A1 (pl) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017289870B2 (en) | 2016-06-30 | 2021-12-23 | Novocure Gmbh | Arrays for longitudinal delivery of TTFields to a body |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| CN118925056A (zh) | 2018-10-15 | 2024-11-12 | 诺沃库勒有限责任公司 | 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields) |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| WO2021111186A1 (en) | 2019-12-02 | 2021-06-10 | Novocure Gmbh | Methods and apparatuses for optimizing transducer array placement |
| CA3163315A1 (en) | 2019-12-31 | 2021-07-08 | Novocure Gmbh | High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels |
| TWI902740B (zh) | 2019-12-31 | 2025-11-01 | 瑞士商諾沃庫勒有限責任公司 | 用於影像分割之方法、系統和設備 |
| CN114830248A (zh) | 2019-12-31 | 2022-07-29 | 诺沃库勒有限责任公司 | 用于电场分布的快速近似的方法、系统和装置 |
| DK4074367T3 (da) | 2019-12-31 | 2023-05-22 | Novocure Gmbh | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
| US20210299440A1 (en) | 2020-03-30 | 2021-09-30 | Novocure Gmbh | Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases |
| WO2021214693A1 (en) | 2020-04-24 | 2021-10-28 | Novocure Gmbh | Using alternating electric fields to increase permeability of the blood brain barrier |
| US11818943B2 (en) | 2020-06-25 | 2023-11-14 | Novocure Gmbh | Fabricating organic light emitting diodes (OLEDs) using tubulin |
| EP4223364B1 (en) * | 2020-09-25 | 2024-04-24 | Novocure GmbH | Varying the metallization area on individual electrode elements in a tumor treating fields system to maximize current without overheating |
| US12194295B2 (en) * | 2020-09-30 | 2025-01-14 | Novocure Gmbh | Method and apparatus for delivering tumor treating fields to a torso, and method for determining locations for transducers to deliver tumor treating fields |
| TWI830958B (zh) * | 2020-10-16 | 2024-02-01 | 瑞士商諾沃庫勒有限責任公司 | 用於判定傳感器陣列在個體之身體上之最佳位置以及規劃電極元件集合在個體之身體上之定位的方法 |
| US11869151B2 (en) * | 2021-01-26 | 2024-01-09 | Beth Israel Deaconess Medical Center | Systems and methods for finite element analysis of tumor treating fields |
| WO2022175803A1 (en) * | 2021-02-17 | 2022-08-25 | Novocure Gmbh | Arrays for delivering tumor treating fields (ttfields) with sets of electrode elements having individually adjustable active areas |
| WO2022190068A1 (en) | 2021-03-12 | 2022-09-15 | Novocure Gmbh | Methods of treating disease by skewing macrophage phenotype with alternating electric fields |
| JP2024513854A (ja) | 2021-03-31 | 2024-03-27 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(TTFields)システムの電極を使用したインピーダンス断層撮影法 |
| JP2024523598A (ja) | 2021-06-30 | 2024-06-28 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(TTfields)を印加するためのトランスデューサアレイにおける電流を調整するためのキャパシタの使用 |
| WO2023275822A1 (en) * | 2021-06-30 | 2023-01-05 | Novocure Gmbh | Nonconductive field guide for resection cavity, and systems and methods of using same |
| JP2024533777A (ja) * | 2021-09-30 | 2024-09-12 | ノボキュア ゲーエムベーハー | 交流電場を用いた被験者の治療における電気感覚の軽減 |
| WO2023111863A1 (en) * | 2021-12-14 | 2023-06-22 | Novocure Gmbh | Transducer array with shape that contours to a subject's body and method of determining shape and placement of transducer arrays |
| US12502548B2 (en) | 2021-12-29 | 2025-12-23 | Novocure Gmbh | Reducing electrosensation whilst treating a subject using alternating electric fields by using larger cathodes and smaller anodes |
| JP2024545019A (ja) | 2021-12-30 | 2024-12-05 | ノボキュア ゲーエムベーハー | 腫瘍治療フィールド(ttfield)を使用した治療のためのパラメータ値の選択 |
| CA3255022A1 (en) | 2022-03-30 | 2023-10-05 | Novocure Gmbh | USE OF INTERLACED COOLING PERIODS TO INCREASE THE MAXIMUM INTENSITY OF TUMOR TREATMENT FIELDS |
| CN119013076A (zh) | 2022-03-30 | 2024-11-22 | 诺沃库勒有限责任公司 | 通过将换能器阵列配对在一起来使用交流电场治疗受试者的同时减少电敏 |
| US12268863B2 (en) | 2023-02-06 | 2025-04-08 | Novocure Gmbh | Shiftable transducer array with anisotropic material layer |
| JP2025537414A (ja) * | 2023-02-06 | 2025-11-14 | ノボキュア ゲーエムベーハー | 異方性材料層を備えた移行可能なトランスデューサアレイ |
| SE2350150A1 (en) * | 2023-02-15 | 2024-08-16 | Force Oncology Ab | Tumor treating fields (ttfields) equipment configurations for improved ease-of-use |
| TW202528013A (zh) | 2023-09-29 | 2025-07-16 | 瑞士商諾沃庫勒有限責任公司 | 使用振幅和頻率的交錯變化來改善交變電場治療期間的電感覺 |
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| CA2972699A1 (en) | 2016-07-10 | 2018-01-10 | Novocure Limited | Synchronizing tumor cells to the g2/m phase using ttfields combined with taxane or other anti-microtubule agents |
| KR102629400B1 (ko) | 2016-08-18 | 2024-01-24 | 노보큐어 리미티드 | 종양치료장을 전달하기 위한 어레이들 내의 온도 측정 |
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| US11109773B2 (en) | 2016-12-13 | 2021-09-07 | Novocure Gmbh | Treating patients with TTFields with the electrode positions optimized using deformable templates |
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| PL421532A1 (pl) * | 2017-05-08 | 2018-11-19 | Michalczyk Marta | System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii |
| WO2018217577A1 (en) * | 2017-05-22 | 2018-11-29 | Thync Global, Inc. | Systems and methods for applying electrical energy to treat medical disorders |
| EP3710102A4 (en) | 2017-11-17 | 2021-08-04 | AbbVie Inc. | METHOD OF TREATMENT OF GLIOBLASTOMA |
| US10953209B2 (en) | 2018-03-28 | 2021-03-23 | Board Of Regents Of The University Of Texas System | Treating tumors using TTFields combined with a PARP inhibitor |
| US11298422B2 (en) | 2018-04-09 | 2022-04-12 | Novocure Gmbh | Treating tumors with TTFields and an aurora kinase inhibitor |
| PL3775956T3 (pl) | 2018-04-10 | 2022-10-10 | Novocure Gmbh | Szacunki przewodności ac o niskiej częstotliwości (< 1 mhz) pozyskane z dwóch obrazów mri o różnych czasach repetycji |
| CN116603165A (zh) | 2018-07-03 | 2023-08-18 | 斯坦福大学托管董事会 | 使用交变电场提高细胞膜通透性 |
| CA3103070C (en) | 2018-07-10 | 2024-01-09 | Novocure Gmbh | Inhibiting viral infection using alternating electric fields |
| US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
| MX2020013431A (es) | 2018-07-18 | 2021-05-27 | Novocure Gmbh | Uso de densidad de perdida de potencia y mediciones relacionadas para cuantificar la dosis de campos de tratamiento de tumores (ttfield). |
| KR20250069692A (ko) | 2018-08-23 | 2025-05-19 | 카스텐 하게만 | 뇌-혈액 장벽 투과성을 향상시키기 위한 교번 전기장의 이용 |
| US11160977B2 (en) * | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
| CN112770806B (zh) | 2018-09-07 | 2025-12-05 | 诺沃库勒有限责任公司 | 使用交变电场治疗自身免疫性疾病以减少t细胞的增殖 |
| US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
| US20200108031A1 (en) | 2018-10-05 | 2020-04-09 | Novocure Gmbh | Treating Tumors Using TTFields Combined with ABT-751 |
| CN118925056A (zh) | 2018-10-15 | 2024-11-12 | 诺沃库勒有限责任公司 | 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields) |
| CN113164525B (zh) | 2018-10-23 | 2025-03-14 | 利兰·斯坦福青年大学托管委员会 | 在基于干细胞的疗法中使用交变电场预防和治疗畸胎瘤形成 |
| US11369790B2 (en) | 2018-10-25 | 2022-06-28 | Novocure Gmbh | Delivering alternating electric fields (e.g., TTFields) to a subject's spinal anatomy |
| US20200146586A1 (en) | 2018-11-14 | 2020-05-14 | Novocure Gmbh | Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images |
| KR102747887B1 (ko) | 2018-11-19 | 2024-12-27 | 노보큐어 게엠베하 | 선택적으로 주소 지정 가능한 하위 요소를 하지는 종양 치료장 제공을 위한 어레이 |
| CN113330485B (zh) | 2019-01-08 | 2025-09-26 | 诺沃库勒有限责任公司 | 评估将图像分割成不同类型组织的质量,用于使用肿瘤治疗场(TTField)来计划治疗 |
| EP3988099B1 (en) | 2019-03-29 | 2023-06-07 | Novocure GmbH | Methods for restoring sensitivity to ttfields in ttfields-resistant cancer cells with ptger3 inhibitors |
| EP3924039B1 (en) | 2019-04-17 | 2023-11-22 | Novocure GmbH | Uploading data from an isolated system without compromising isolation |
| USD934892S1 (en) | 2019-05-03 | 2021-11-02 | Novocure Gmbh | Display screen or portion thereof with a graphical user interface |
| CN114364432B (zh) | 2019-07-31 | 2025-10-31 | 诺沃库勒有限责任公司 | 经由埋入颅骨植入物中的电极施加肿瘤治疗场(TTField) |
| US12343336B2 (en) | 2019-08-05 | 2025-07-01 | Novocure Gmbh | Increasing cancer cells' sensitivity to tumor treating fields (TTFields) by inhibiting IL11 activity |
| US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
| EP4028052A1 (en) | 2019-09-10 | 2022-07-20 | Novocure GmbH | A method of reducing viability of cancer cells by applying alternating electric fields and administering checkpoint inhibitors to the cancer cells |
| EP4081257A1 (en) | 2019-12-26 | 2022-11-02 | The Board of Trustees of the Leland Stanford Junior University | Methods of normalizing aberrant glycolytic metabolism in cancer cells |
| CA3163315A1 (en) | 2019-12-31 | 2021-07-08 | Novocure Gmbh | High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels |
| DK4074367T3 (da) | 2019-12-31 | 2023-05-22 | Novocure Gmbh | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
| US20210299440A1 (en) | 2020-03-30 | 2021-09-30 | Novocure Gmbh | Intravenous / Intra-Spinal / Intra-Cavity / Intraventricular Delivery of TTFields (Tumor Treating Fields) for Treating Cancer and Metastases |
| WO2021214693A1 (en) | 2020-04-24 | 2021-10-28 | Novocure Gmbh | Using alternating electric fields to increase permeability of the blood brain barrier |
-
2019
- 2019-10-11 CN CN202411342709.XA patent/CN118925056A/zh active Pending
- 2019-10-11 EP EP19797802.6A patent/EP3840823B1/en active Active
- 2019-10-11 US US16/599,725 patent/US11154707B2/en active Active
- 2019-10-11 PL PL21205743.4T patent/PL3984590T3/pl unknown
- 2019-10-11 CN CN201980063982.XA patent/CN112930209B/zh active Active
- 2019-10-11 WO PCT/IB2019/058709 patent/WO2020079554A1/en not_active Ceased
- 2019-10-11 CN CN202411342713.6A patent/CN118925057A/zh active Pending
- 2019-10-11 EP EP22198125.1A patent/EP4137195B1/en active Active
- 2019-10-11 EP EP21159490.8A patent/EP3878505B1/en active Active
- 2019-10-11 JP JP2021520224A patent/JP7284886B2/ja active Active
- 2019-10-11 HU HUE21205743A patent/HUE061361T2/hu unknown
- 2019-10-11 US US16/599,686 patent/US11241577B2/en active Active
- 2019-10-11 EP EP21205743.4A patent/EP3984590B1/en active Active
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- 2023-03-22 JP JP2023045799A patent/JP7536934B2/ja active Active
- 2023-11-13 US US18/388,951 patent/US12208275B2/en active Active
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| US20240082592A1 (en) | 2024-03-14 |
| JP2022512690A (ja) | 2022-02-07 |
| EP4137195A1 (en) | 2023-02-22 |
| US20200114141A1 (en) | 2020-04-16 |
| CN112930209A (zh) | 2021-06-08 |
| US11865355B2 (en) | 2024-01-09 |
| US20220118249A1 (en) | 2022-04-21 |
| CN112930209B (zh) | 2024-10-15 |
| CN118925056A (zh) | 2024-11-12 |
| EP3984590B1 (en) | 2022-12-07 |
| EP3984590A1 (en) | 2022-04-20 |
| JP7536934B2 (ja) | 2024-08-20 |
| US12208275B2 (en) | 2025-01-28 |
| EP3840823B1 (en) | 2023-07-12 |
| EP4137195B1 (en) | 2024-12-11 |
| US11154707B2 (en) | 2021-10-26 |
| EP3878505A1 (en) | 2021-09-15 |
| HUE061361T2 (hu) | 2023-06-28 |
| US20200114142A1 (en) | 2020-04-16 |
| EP3840823A1 (en) | 2021-06-30 |
| US11241577B2 (en) | 2022-02-08 |
| JP7284886B2 (ja) | 2023-06-01 |
| EP3878505B1 (en) | 2023-05-24 |
| EP3840823C0 (en) | 2023-07-12 |
| JP2023083291A (ja) | 2023-06-15 |
| EP4137195C0 (en) | 2024-12-11 |
| WO2020079554A1 (en) | 2020-04-23 |
| CN118925057A (zh) | 2024-11-12 |
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