JP2019503980A5 - - Google Patents
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- JP2019503980A5 JP2019503980A5 JP2017562979A JP2017562979A JP2019503980A5 JP 2019503980 A5 JP2019503980 A5 JP 2019503980A5 JP 2017562979 A JP2017562979 A JP 2017562979A JP 2017562979 A JP2017562979 A JP 2017562979A JP 2019503980 A5 JP2019503980 A5 JP 2019503980A5
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- JP
- Japan
- Prior art keywords
- ligand
- complex
- linker
- alkyl
- conjugate
- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562260046P | 2015-11-25 | 2015-11-25 | |
| US62/260,046 | 2015-11-25 | ||
| PCT/IB2016/001772 WO2017089890A1 (en) | 2015-11-25 | 2016-11-23 | Conjugates comprising self-immolative groups and methods related thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019503980A JP2019503980A (ja) | 2019-02-14 |
| JP2019503980A5 true JP2019503980A5 (https=) | 2020-01-09 |
| JP6949732B2 JP6949732B2 (ja) | 2021-10-13 |
Family
ID=58763083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017562979A Active JP6949732B2 (ja) | 2015-11-25 | 2016-11-23 | 自壊性基を含む複合体及びそれに関連した方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11413353B2 (https=) |
| EP (1) | EP3380124B1 (https=) |
| JP (1) | JP6949732B2 (https=) |
| KR (1) | KR102847342B1 (https=) |
| CN (4) | CN117244076A (https=) |
| AU (1) | AU2016359230B2 (https=) |
| CA (1) | CA3006242A1 (https=) |
| DK (1) | DK3380124T3 (https=) |
| ES (1) | ES2979090T3 (https=) |
| FI (1) | FI3380124T3 (https=) |
| HR (1) | HRP20240795T1 (https=) |
| HU (1) | HUE067016T2 (https=) |
| LT (1) | LT3380124T (https=) |
| PL (1) | PL3380124T3 (https=) |
| PT (1) | PT3380124T (https=) |
| RS (1) | RS65660B1 (https=) |
| SI (1) | SI3380124T1 (https=) |
| SM (1) | SMT202400223T1 (https=) |
| TW (1) | TWI801332B (https=) |
| WO (1) | WO2017089890A1 (https=) |
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| KR102847350B1 (ko) | 2015-11-25 | 2025-08-19 | 주식회사 리가켐바이오사이언스 | 분지된 링커를 포함하는 항체-약물 접합체 및 이의 제조방법 |
| GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
| EP3535299A1 (en) | 2016-11-04 | 2019-09-11 | Novimmune S.A. | Anti-cd19 antibodies and methods of use thereof |
| MX2019011655A (es) | 2017-03-29 | 2019-12-19 | Legochem Biosciences Inc | Profarmaco de dimero de pirrolobenzodiazepina y compuesto conjugado ligando-conector de este. |
| MX2019015057A (es) | 2017-06-23 | 2020-08-03 | Velosbio Inc | Inmunoconjugados de anticuerpos receptor huérfano similar al receptor tirosina cinasa 1 (ror1). |
| KR20190018400A (ko) | 2017-08-14 | 2019-02-22 | 주식회사 레고켐 바이오사이언스 | EGFRvIII에 대한 항체를 포함하는 항체 약물 접합체 |
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| WO2019225777A1 (ko) | 2018-05-23 | 2019-11-28 | 에이비엘바이오 주식회사 | 항-ror1 항체 및 그 용도 |
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| KR20210028544A (ko) * | 2019-09-04 | 2021-03-12 | 주식회사 레고켐 바이오사이언스 | 인간 ror1에 대한 항체를 포함하는 항체 약물 접합체 및 이의 용도 |
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2016
- 2016-11-23 HR HRP20240795TT patent/HRP20240795T1/hr unknown
- 2016-11-23 EP EP16868091.6A patent/EP3380124B1/en active Active
- 2016-11-23 FI FIEP16868091.6T patent/FI3380124T3/fi active
- 2016-11-23 CA CA3006242A patent/CA3006242A1/en active Pending
- 2016-11-23 WO PCT/IB2016/001772 patent/WO2017089890A1/en not_active Ceased
- 2016-11-23 US US15/779,446 patent/US11413353B2/en active Active
- 2016-11-23 LT LTEPPCT/IB2016/001772T patent/LT3380124T/lt unknown
- 2016-11-23 RS RS20240697A patent/RS65660B1/sr unknown
- 2016-11-23 SM SM20240223T patent/SMT202400223T1/it unknown
- 2016-11-23 CN CN202311147181.6A patent/CN117244076A/zh active Pending
- 2016-11-23 AU AU2016359230A patent/AU2016359230B2/en active Active
- 2016-11-23 SI SI201631824T patent/SI3380124T1/sl unknown
- 2016-11-23 HU HUE16868091A patent/HUE067016T2/hu unknown
- 2016-11-23 CN CN202011108071.5A patent/CN112451682A/zh active Pending
- 2016-11-23 JP JP2017562979A patent/JP6949732B2/ja active Active
- 2016-11-23 PT PT168680916T patent/PT3380124T/pt unknown
- 2016-11-23 PL PL16868091.6T patent/PL3380124T3/pl unknown
- 2016-11-23 CN CN201680030770.8A patent/CN107847606A/zh active Pending
- 2016-11-23 DK DK16868091.6T patent/DK3380124T3/da active
- 2016-11-23 CN CN202410065862.6A patent/CN118105513A/zh active Pending
- 2016-11-23 ES ES16868091T patent/ES2979090T3/es active Active
- 2016-11-23 KR KR1020187018066A patent/KR102847342B1/ko active Active
- 2016-11-25 TW TW105138775A patent/TWI801332B/zh active
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