JP2018511326A5 - - Google Patents

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Publication number
JP2018511326A5
JP2018511326A5 JP2017551164A JP2017551164A JP2018511326A5 JP 2018511326 A5 JP2018511326 A5 JP 2018511326A5 JP 2017551164 A JP2017551164 A JP 2017551164A JP 2017551164 A JP2017551164 A JP 2017551164A JP 2018511326 A5 JP2018511326 A5 JP 2018511326A5
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JP
Japan
Prior art keywords
protoxin
pain
variant
seq
isolated
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Application number
JP2017551164A
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English (en)
Japanese (ja)
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JP2018511326A (ja
JP6985151B2 (ja
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Application filed filed Critical
Priority claimed from PCT/US2016/025247 external-priority patent/WO2016161100A1/en
Publication of JP2018511326A publication Critical patent/JP2018511326A/ja
Publication of JP2018511326A5 publication Critical patent/JP2018511326A5/ja
Priority to JP2021153626A priority Critical patent/JP2022008474A/ja
Application granted granted Critical
Publication of JP6985151B2 publication Critical patent/JP6985151B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017551164A 2015-04-02 2016-03-31 プロトキシン−ii変異体及びその使用方法 Expired - Fee Related JP6985151B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021153626A JP2022008474A (ja) 2015-04-02 2021-09-21 プロトキシン-ii変異体及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562142069P 2015-04-02 2015-04-02
US62/142,069 2015-04-02
PCT/US2016/025247 WO2016161100A1 (en) 2015-04-02 2016-03-31 Protoxin-ii variants and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021153626A Division JP2022008474A (ja) 2015-04-02 2021-09-21 プロトキシン-ii変異体及びその使用方法

Publications (3)

Publication Number Publication Date
JP2018511326A JP2018511326A (ja) 2018-04-26
JP2018511326A5 true JP2018511326A5 (enExample) 2019-05-09
JP6985151B2 JP6985151B2 (ja) 2021-12-22

Family

ID=57006450

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017551164A Expired - Fee Related JP6985151B2 (ja) 2015-04-02 2016-03-31 プロトキシン−ii変異体及びその使用方法
JP2021153626A Withdrawn JP2022008474A (ja) 2015-04-02 2021-09-21 プロトキシン-ii変異体及びその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021153626A Withdrawn JP2022008474A (ja) 2015-04-02 2021-09-21 プロトキシン-ii変異体及びその使用方法

Country Status (16)

Country Link
US (3) US10463714B2 (enExample)
EP (2) EP3960757A1 (enExample)
JP (2) JP6985151B2 (enExample)
KR (1) KR20170134542A (enExample)
CN (1) CN107921089A (enExample)
AR (1) AR104173A1 (enExample)
AU (2) AU2016242905B2 (enExample)
BR (1) BR112017020896A2 (enExample)
CA (1) CA2981336A1 (enExample)
ES (1) ES2888799T3 (enExample)
IL (2) IL254599B (enExample)
MA (1) MA41864A (enExample)
MX (1) MX2017012654A (enExample)
TW (1) TW201708249A (enExample)
UY (1) UY36602A (enExample)
WO (1) WO2016161100A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10414808B2 (en) 2012-05-18 2019-09-17 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
ES2841173T3 (es) 2013-10-03 2021-07-07 Janssen Biotech Inc Variantes de Protoxina-II y métodos de uso
MA41642A (fr) 2015-03-03 2018-01-09 Janssen Biotech Inc Variants de protoxine ii et méthodes d'utilisation
TW201708249A (zh) 2015-04-02 2017-03-01 健生生物科技公司 原毒素-ii變體及使用方法
TWI724392B (zh) 2018-04-06 2021-04-11 美商美國禮來大藥廠 生長分化因子15促效劑化合物及其使用方法
CN109369784B (zh) * 2018-11-14 2019-08-30 青海芬陀利华生物科技有限公司 PaTx-1毒素及其应用
WO2021252448A1 (en) * 2020-06-10 2021-12-16 Memorial Sloan Kettering Cancer Center Imaging compounds selective for nav1.7

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US20030148273A1 (en) * 2000-08-26 2003-08-07 Shoulian Dong Target enrichment and amplification
EP1348466A3 (en) 2002-02-01 2003-10-29 Inspire Pharmaceuticals, Inc. Method for treating pain with adenosine-tetraphosphates
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US7833979B2 (en) 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
WO2007056326A2 (en) 2005-11-04 2007-05-18 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of nav1.8 gene
WO2007109324A2 (en) 2006-03-21 2007-09-27 Xenon Pharmaceuticals, Inc. Potent and selective nav 1.7 sodium channel blockers
MX2009002504A (es) 2006-09-08 2009-05-22 Mayo Foundation Polipeptidos acuareticos y natriureticos que carecen de actividad vasodilatadora.
WO2008033564A1 (en) 2006-09-15 2008-03-20 Hydra Biosciences Inc. Compounds for modulating trpv3 function
AR063384A1 (es) 2006-10-25 2009-01-28 Amgen Inc Agentes terapeuticos a base de peptidos derivados de toxinas
CN102202677A (zh) 2008-09-03 2011-09-28 阿尔伯维塔公司 治疗疼痛的活性剂和方法
WO2010104115A1 (ja) 2009-03-10 2010-09-16 独立行政法人産業技術総合研究所 膜タンパク質を特異的に認識するポリペプチドの調製方法
SG179101A1 (en) 2009-09-15 2012-05-30 Alomone Preclinical Ltd Novel peptides isolated from spider venom, and uses thereof
JP5795341B2 (ja) * 2010-03-08 2015-10-14 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 参照ブロック配列によるfullCOLD−PCR濃縮
US9279003B2 (en) 2010-07-07 2016-03-08 Purdue Pharma L.P. Analogs of sodium channel peptide toxin
CN101979411A (zh) 2010-10-21 2011-02-23 湖南师范大学 虎纹捕鸟蛛蛋白酶抑制剂
JP2014507136A (ja) 2011-01-18 2014-03-27 アムジエン・インコーポレーテツド NaV1.7ノックアウトマウスとそれらの使用
EP2705162B1 (en) * 2011-05-04 2018-07-11 Biocept, Inc. Methods for detecting nucleic acid sequence variants
US9102751B2 (en) 2012-05-18 2015-08-11 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
EP3973981A1 (en) 2012-05-18 2022-03-30 Janssen Biotech, Inc. Huwentoxin-iv variants and methods of use
US10414808B2 (en) 2012-05-18 2019-09-17 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
US9718865B2 (en) 2012-07-27 2017-08-01 Purdue Pharma L.P. Sodium channel blocking peptides and the use thereof
WO2014165277A2 (en) 2013-03-12 2014-10-09 Amgen Inc. POTENT AND SELECTIVE INHIBITORS OF Nav1.7
CN104065367B (zh) 2013-03-20 2017-11-07 江苏多维科技有限公司 一种低功耗磁电阻开关传感器
ES2841173T3 (es) 2013-10-03 2021-07-07 Janssen Biotech Inc Variantes de Protoxina-II y métodos de uso
MA41642A (fr) * 2015-03-03 2018-01-09 Janssen Biotech Inc Variants de protoxine ii et méthodes d'utilisation
TW201708249A (zh) 2015-04-02 2017-03-01 健生生物科技公司 原毒素-ii變體及使用方法

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