JP2018510657A - 改変ｔ細胞ならびにそれを作製および使用する方法 - Google Patents

改変ｔ細胞ならびにそれを作製および使用する方法 Download PDF

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JP2018510657A
JP2018510657A JP2018502061A JP2018502061A JP2018510657A JP 2018510657 A JP2018510657 A JP 2018510657A JP 2018502061 A JP2018502061 A JP 2018502061A JP 2018502061 A JP2018502061 A JP 2018502061A JP 2018510657 A JP2018510657 A JP 2018510657A
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cell
cells
seq
protein
sequence
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JP2018510657A5 (enExample
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トルステン ビー． マイスナー，
トルステン ビー． マイスナー，
カブンゴ ワイ． ムルンバ，
カブンゴ ワイ． ムルンバ，
レオナルド エム．アール． フェレイラ，
レオナルド エム．アール． フェレイラ，
チャド エー． コーワン，
チャド エー． コーワン，
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Harvard University
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Harvard University
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Priority to JP2021100691A priority Critical patent/JP2021137036A/ja
Priority to JP2023122393A priority patent/JP2023129663A/ja
Priority to JP2025157397A priority patent/JP2025181962A/ja
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JP2018502061A 2015-03-27 2016-03-28 改変ｔ細胞ならびにそれを作製および使用する方法 Pending JP2018510657A (ja)

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JP2021100691A JP2021137036A (ja) 2015-03-27 2021-06-17 改変ｔ細胞ならびにそれを作製および使用する方法
JP2023122393A JP2023129663A (ja) 2015-03-27 2023-07-27 改変ｔ細胞ならびにそれを作製および使用する方法
JP2025157397A JP2025181962A (ja) 2015-03-27 2025-09-22 改変ｔ細胞ならびにそれを作製および使用する方法

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US201562139479P 2015-03-27 2015-03-27
US62/139,479 2015-03-27
PCT/US2016/024554 WO2016160721A1 (en) 2015-03-27 2016-03-28 Modified t cells and methods of making and using the same

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JP2021100691A Withdrawn JP2021137036A (ja) 2015-03-27 2021-06-17 改変ｔ細胞ならびにそれを作製および使用する方法
JP2023122393A Pending JP2023129663A (ja) 2015-03-27 2023-07-27 改変ｔ細胞ならびにそれを作製および使用する方法
JP2025157397A Pending JP2025181962A (ja) 2015-03-27 2025-09-22 改変ｔ細胞ならびにそれを作製および使用する方法

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JP2023122393A Pending JP2023129663A (ja) 2015-03-27 2023-07-27 改変ｔ細胞ならびにそれを作製および使用する方法
JP2025157397A Pending JP2025181962A (ja) 2015-03-27 2025-09-22 改変ｔ細胞ならびにそれを作製および使用する方法

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EP (2) EP4269601A3 (enExample)
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KR (1) KR20180020125A (enExample)
CN (2) CN107847524A (enExample)
AU (3) AU2016243583B2 (enExample)
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Cited By (5)

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JP2021520211A (ja) * 2018-04-05 2021-08-19 ジュノー セラピューティクス インコーポレイテッド 組換え受容体を発現するｔ細胞、関連ポリヌクレオチド、および方法
JP2021137036A (ja) * 2015-03-27 2021-09-16 プレジデント アンド フェローズ オブ ハーバード カレッジ 改変ｔ細胞ならびにそれを作製および使用する方法
JP2021525518A (ja) * 2018-05-31 2021-09-27 ワシントン・ユニバーシティＷａｓｈｉｎｇｔｏｎ Ｕｎｉｖｅｒｓｉｔｙ 細胞をゲノム編集及び活性化するための方法
JP2022512703A (ja) * 2018-10-16 2022-02-07 インテリア セラピューティクス，インコーポレイテッド 免疫療法のための組成物および方法
JP2023519819A (ja) * 2020-03-13 2023-05-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 標的核酸を改変するための組成物および方法

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CN107921148A (zh) 2015-05-08 2018-04-17 哈佛学院校长同事会 通用供体干细胞和相关方法
CN107949641A (zh) * 2015-06-17 2018-04-20 Uab研究基金会 用于基因组编辑的crispr/cas9复合物
JP2018518181A (ja) * 2015-06-17 2018-07-12 ザ ユーエービー リサーチ ファンデーション 血液細胞系列の細胞に機能的ポリペプチドを導入するためのＣＲＩＳＰＲ／Ｃａｓ９複合体
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EP3317401B1 (en) * 2015-07-29 2018-10-03 Onkimmune Limited Modified natural killer cells and natural killer cell lines having increased cytotoxicity
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CA2993431A1 (en) 2015-07-31 2017-02-09 Regents Of The University Of Minnesota Nuclease based knockouts of immunological checkpoint genes in immune cells
AU2016316033B2 (en) 2015-09-04 2022-03-03 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of use
ES2883116T3 (es) 2015-10-05 2021-12-07 Prec Biosciences Inc Meganucleasas diseñadas con secuencias de reconocimiento encontradas en el gen de la región constante alfa del receptor de células T humanas
CN108601821B (zh) 2015-10-05 2023-09-19 精密生物科学公司 包含经修饰的人T细胞受体α恒定区基因的经遗传修饰的细胞
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CN109475109B (zh) 2016-05-20 2021-10-29 瑞泽恩制药公司 用于使用多个引导rna来破坏免疫耐受性的方法
CN109863242A (zh) * 2016-08-30 2019-06-07 纪念斯隆-凯特林癌症中心 用于治疗病毒感染和其它感染的免疫细胞组合物和使用方法
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