JP2018506981A - 抗ｄｌｌ３キメラ抗原受容体および使用方法 - Google Patents

抗ｄｌｌ３キメラ抗原受容体および使用方法 Download PDF

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JP2018506981A
JP2018506981A JP2017544615A JP2017544615A JP2018506981A JP 2018506981 A JP2018506981 A JP 2018506981A JP 2017544615 A JP2017544615 A JP 2017544615A JP 2017544615 A JP2017544615 A JP 2017544615A JP 2018506981 A JP2018506981 A JP 2018506981A
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seq
dll3
cells
antibody
cell
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JP2018506981A5 (enExample
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エスカルプ，ポール・アンソニー
ダイラ，スコット・ジェイ
リウ，デイビッド
スタル，ロバート・エイ
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アッヴィ・ステムセントルクス・エル・エル・シー
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JP2017544615A 2015-02-23 2016-02-23 抗ｄｌｌ３キメラ抗原受容体および使用方法 Pending JP2018506981A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562119793P 2015-02-23 2015-02-23
US62/119,793 2015-02-23
US201562241662P 2015-10-14 2015-10-14
US62/241,662 2015-10-14
US201662296560P 2016-02-17 2016-02-17
US62/296,560 2016-02-17
PCT/US2016/019192 WO2016138038A1 (en) 2015-02-23 2016-02-23 Anti-dll3 chimeric antigen receptors and methods of use

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JP2018506981A true JP2018506981A (ja) 2018-03-15
JP2018506981A5 JP2018506981A5 (enExample) 2019-04-04

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US (1) US20180044415A1 (enExample)
EP (1) EP3261650A4 (enExample)
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KR (1) KR20170120158A (enExample)
CN (1) CN107405362A (enExample)
BR (1) BR112017017927A2 (enExample)
CA (1) CA2977502A1 (enExample)
CL (1) CL2017002150A1 (enExample)
CO (1) CO2017008804A2 (enExample)
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Cited By (6)

* Cited by examiner, † Cited by third party
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JP2021520788A (ja) * 2018-04-10 2021-08-26 アムジエン・インコーポレーテツド Ｄｌｌ３に対するキメラ受容体及びその使用方法
JP2021528047A (ja) * 2018-05-08 2021-10-21 フェインズ セラピューティクス，インコーポレーテッド 抗ｄｌｌ３抗体及びその使用
JP2022504822A (ja) * 2018-10-11 2022-01-13 インヒブルクス インコーポレイテッド Ｄｌｌ３シングルドメイン抗体およびその治療用組成物
JP2022523781A (ja) * 2019-03-01 2022-04-26 アロジーン セラピューティクス，インコーポレイテッド Ｄｌｌ３標的化キメラ抗原受容体および結合剤
JP2022542543A (ja) * 2019-07-17 2022-10-05 ナンジン レジェンド バイオテック カンパニー，リミテッド 抗ｄｌｌ３キメラ抗原受容体及びその使用
JP2023548590A (ja) * 2020-11-06 2023-11-17 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 小細胞肺がんの分類と治療のための方法およびシステム

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US11982673B2 (en) 2014-03-05 2024-05-14 Autolus Limited Methods
GB201403972D0 (en) 2014-03-06 2014-04-23 Ucl Business Plc Chimeric antigen receptor
US9708412B2 (en) 2015-05-21 2017-07-18 Harpoon Therapeutics, Inc. Trispecific binding proteins and methods of use
EP3493844A4 (en) 2016-05-20 2021-03-24 Harpoon Therapeutics Inc. SINGLE DOMAIN SERUM ALBUMIN BINDING PROTEIN
CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技（香港）有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
AU2018219887B2 (en) 2017-02-08 2024-08-15 Dragonfly Therapeutics, LLC Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
CN110944661A (zh) 2017-02-20 2020-03-31 蜻蜓疗法股份有限公司 结合her2、nkg2d和cd16的蛋白质
JP2020530554A (ja) * 2017-07-20 2020-10-22 シートムエックス セラピューティクス，インコーポレイテッド 活性化抗体の特性を定性的および／または定量的に分析する方法およびその使用
KR102172092B1 (ko) 2017-09-19 2020-10-30 주식회사 엘지화학 열가소성 수지 조성물, 이의 제조방법 및 성형품
IL315737A (en) 2017-10-13 2024-11-01 Harpoon Therapeutics Inc B-cell maturation antigen-binding proteins
MX2020003915A (es) 2017-10-13 2020-10-08 Harpoon Therapeutics Inc Proteinas trispecificas y metodos de uso.
EP3698140A4 (en) * 2017-10-20 2021-07-28 NantBio, Inc. BLADDER CANCER IMMUNOTHERAPY SURVEILLANCE METHODS
BR112020015994A2 (pt) 2018-02-08 2020-12-15 Dragonfly Therapeutics, Inc. Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer
CA3237846A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
CN111989108B (zh) * 2018-02-13 2024-07-16 嵌合体生物工程公司 利用rna去稳定元件协调基因表达
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