JP2018506981A - 抗ｄｌｌ３キメラ抗原受容体および使用方法 - Google Patents

抗ｄｌｌ３キメラ抗原受容体および使用方法 Download PDF

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JP2018506981A
JP2018506981A JP2017544615A JP2017544615A JP2018506981A JP 2018506981 A JP2018506981 A JP 2018506981A JP 2017544615 A JP2017544615 A JP 2017544615A JP 2017544615 A JP2017544615 A JP 2017544615A JP 2018506981 A JP2018506981 A JP 2018506981A
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seq
dll3
cells
antibody
cell
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JP2018506981A5 (enExample
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エスカルプ，ポール・アンソニー
ダイラ，スコット・ジェイ
リウ，デイビッド
スタル，ロバート・エイ
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アッヴィ・ステムセントルクス・エル・エル・シー
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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JP2017544615A 2015-02-23 2016-02-23 抗ｄｌｌ３キメラ抗原受容体および使用方法 Pending JP2018506981A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562119793P 2015-02-23 2015-02-23
US62/119,793 2015-02-23
US201562241662P 2015-10-14 2015-10-14
US62/241,662 2015-10-14
US201662296560P 2016-02-17 2016-02-17
US62/296,560 2016-02-17
PCT/US2016/019192 WO2016138038A1 (en) 2015-02-23 2016-02-23 Anti-dll3 chimeric antigen receptors and methods of use

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JP2018506981A true JP2018506981A (ja) 2018-03-15
JP2018506981A5 JP2018506981A5 (enExample) 2019-04-04

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US (1) US20180044415A1 (enExample)
EP (1) EP3261650A4 (enExample)
JP (1) JP2018506981A (enExample)
KR (1) KR20170120158A (enExample)
CN (1) CN107405362A (enExample)
BR (1) BR112017017927A2 (enExample)
CA (1) CA2977502A1 (enExample)
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Cited By (5)

* Cited by examiner, † Cited by third party
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JP2021520788A (ja) * 2018-04-10 2021-08-26 アムジエン・インコーポレーテツド Ｄｌｌ３に対するキメラ受容体及びその使用方法
JP2021528047A (ja) * 2018-05-08 2021-10-21 フェインズ セラピューティクス，インコーポレーテッド 抗ｄｌｌ３抗体及びその使用
JP2022504822A (ja) * 2018-10-11 2022-01-13 インヒブルクス インコーポレイテッド Ｄｌｌ３シングルドメイン抗体およびその治療用組成物
JP2022523781A (ja) * 2019-03-01 2022-04-26 アロジーン セラピューティクス，インコーポレイテッド Ｄｌｌ３標的化キメラ抗原受容体および結合剤
JP2022542543A (ja) * 2019-07-17 2022-10-05 ナンジン レジェンド バイオテック カンパニー，リミテッド 抗ｄｌｌ３キメラ抗原受容体及びその使用

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GB201403972D0 (en) 2014-03-06 2014-04-23 Ucl Business Plc Chimeric antigen receptor
CA2986575A1 (en) 2015-05-21 2016-11-24 Harpoon Therapeutics, Inc. Trispecific binding proteins and methods of use
CN108395482B (zh) 2017-02-08 2021-02-05 西比曼生物科技（香港）有限公司 一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
KR20190118172A (ko) 2017-02-08 2019-10-17 드래곤플라이 쎄라퓨틱스, 인크. 천연 킬러 세포의 활성화를 위한 다중-특이적 결합 단백질 및 암 치료에서의 그의 치료적 용도
EP4273258A3 (en) 2017-02-20 2024-01-17 Dragonfly Therapeutics, Inc. Proteins binding her2, nkg2d and cd16
EP3655779A1 (en) * 2017-07-20 2020-05-27 CytomX Therapeutics, Inc. Methods of qualitatively and/or quantitatively analyzing properties of activatable antibodies and uses thereof
KR102172092B1 (ko) 2017-09-19 2020-10-30 주식회사 엘지화학 열가소성 수지 조성물, 이의 제조방법 및 성형품
CN111630070B (zh) 2017-10-13 2024-07-30 哈普恩治疗公司 三特异性蛋白质及使用方法
IL315737A (en) 2017-10-13 2024-11-01 Harpoon Therapeutics Inc B-cell maturation antigen-binding proteins
KR20200074966A (ko) * 2017-10-20 2020-06-25 난트바이오 인코포레이티드 방광암 면역요법을 모니터링하는 방법
MX2020008333A (es) 2018-02-08 2020-09-21 Dragonfly Therapeutics Inc Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales.
WO2019157366A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
WO2019160815A1 (en) * 2018-02-13 2019-08-22 Chimera Bioengineering, Inc. Coordinating gene expression using rna destabilizing elements
MX2020008684A (es) 2018-02-20 2020-12-07 Dragonfly Therapeutics Inc Proteinas de union multiespecificas que se unen a cd33, nkg2d y cd16 y metodos de uso.
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