JP2018502583A5 - - Google Patents
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- JP2018502583A5 JP2018502583A5 JP2017536779A JP2017536779A JP2018502583A5 JP 2018502583 A5 JP2018502583 A5 JP 2018502583A5 JP 2017536779 A JP2017536779 A JP 2017536779A JP 2017536779 A JP2017536779 A JP 2017536779A JP 2018502583 A5 JP2018502583 A5 JP 2018502583A5
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- JP
- Japan
- Prior art keywords
- variant
- gene
- polynucleotide
- seq
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562102569P | 2015-01-12 | 2015-01-12 | |
| US62/102,569 | 2015-01-12 | ||
| PCT/US2016/013109 WO2016115177A1 (en) | 2015-01-12 | 2016-01-12 | Modified hepatitis post-transcriptional regulatory elements |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018502583A JP2018502583A (ja) | 2018-02-01 |
| JP2018502583A5 true JP2018502583A5 (enExample) | 2019-02-21 |
| JP6868560B2 JP6868560B2 (ja) | 2021-05-12 |
Family
ID=55310922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017536779A Active JP6868560B2 (ja) | 2015-01-12 | 2016-01-12 | 修飾された肝炎転写後調節エレメント |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10363269B2 (enExample) |
| EP (1) | EP3245292B1 (enExample) |
| JP (1) | JP6868560B2 (enExample) |
| KR (1) | KR102554374B1 (enExample) |
| CN (1) | CN107429260B (enExample) |
| AU (1) | AU2016206868B2 (enExample) |
| BR (1) | BR112017014917A2 (enExample) |
| CA (1) | CA2973483A1 (enExample) |
| ES (1) | ES2877367T3 (enExample) |
| IL (1) | IL253399B2 (enExample) |
| MA (1) | MA41346A (enExample) |
| MX (1) | MX391694B (enExample) |
| MY (1) | MY187559A (enExample) |
| RU (1) | RU2734594C2 (enExample) |
| SA (1) | SA517381912B1 (enExample) |
| SG (1) | SG11201705692SA (enExample) |
| WO (1) | WO2016115177A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113736828A (zh) | 2014-11-05 | 2021-12-03 | 朱诺治疗学股份有限公司 | 用于转导及细胞处理的方法 |
| AU2016301196B2 (en) | 2015-08-06 | 2022-09-08 | Dana-Farber Cancer Institute, Inc. | Tunable endogenous protein degradation |
| CN109641063B (zh) | 2016-04-20 | 2022-11-15 | 能源环境和技术研究中心O.A., M.P. | 用于增强pklr的基因表达的组合物和方法 |
| CN110022904B (zh) | 2016-10-20 | 2024-04-19 | 桑格摩生物治疗股份有限公司 | 用于治疗法布里病的方法和组合物 |
| CN107058315B (zh) * | 2016-12-08 | 2019-11-08 | 上海优卡迪生物医药科技有限公司 | 敲减人PD-1的siRNA、重组表达CAR-T载体及其构建方法和应用 |
| EP3580212A4 (en) * | 2017-02-08 | 2021-03-17 | Dana Farber Cancer Institute, Inc. | REGULATION OF CHEMERIC ANTIGEN RECEPTORS |
| US11713468B2 (en) * | 2017-08-02 | 2023-08-01 | Dna Twopointo Inc. | DNA vectors and elements for sustained gene expression in eukaryotic cells |
| CN111148533A (zh) | 2017-09-19 | 2020-05-12 | 麻省理工学院 | 用于嵌合抗原受体t细胞疗法的组合物及其用途 |
| SG11202002263TA (en) | 2017-10-16 | 2020-04-29 | Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas | Lentiviral vectors for delivery of pklr to treat pyruvate kinase deficiency |
| JP7576754B2 (ja) | 2018-04-11 | 2024-11-01 | スペースクラフト セブン リミテッド ライアビリティ カンパニー | 幹細胞移植のための組成物および方法 |
| AU2019261646A1 (en) | 2018-04-27 | 2020-11-12 | Spacecraft Seven, Llc | Gene therapy for CNS degeneration |
| AU2019346335B2 (en) | 2018-09-28 | 2024-07-25 | Massachusetts Institute Of Technology | Collagen-localized immunomodulatory molecules and methods thereof |
| MA55628A (fr) | 2019-04-12 | 2022-02-16 | C4 Therapeutics Inc | Agents de dégradation tricycliques d'ikaros et d'aiolos |
| CN111825769B (zh) * | 2019-04-16 | 2022-03-25 | 上海科技大学 | 一种泛素化缺失的嵌合抗原受体及其用途 |
| US20230038502A1 (en) | 2019-06-11 | 2023-02-09 | Shire Human Genetic Therapies, Inc. | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| US11642409B2 (en) | 2019-06-26 | 2023-05-09 | Massachusetts Insttute of Technology | Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof |
| WO2021061648A1 (en) | 2019-09-23 | 2021-04-01 | Massachusetts Institute Of Technology | Methods and compositions for stimulation of endogenous t cell responses |
| EP4048800A1 (en) | 2019-10-23 | 2022-08-31 | Shire Human Genetic Therapies, Inc. | Adeno-associated virus vectors based gene therapy for hereditary angioedema |
| US11896619B2 (en) | 2020-03-10 | 2024-02-13 | Massachusetts Institute Of Technology | Compositions and methods for immunotherapy of NPM1c-positive cancer |
| CA3173527A1 (en) | 2020-03-10 | 2021-09-16 | Massachusetts Institute Of Technology | Methods for generating engineered memory-like nk cells and compositions thereof |
| DE102020106710A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| DE102020111571A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| CA3181339A1 (en) | 2020-04-27 | 2021-11-04 | Juno Therapeutics, Inc. | Stabilization of polyethyleneimine-deoxyribonucleic acid complex size and activity |
| WO2021221782A1 (en) | 2020-05-01 | 2021-11-04 | Massachusetts Institute Of Technology | Chimeric antigen receptor-targeting ligands and uses thereof |
| WO2021221783A1 (en) | 2020-05-01 | 2021-11-04 | Massachusetts Institute Of Technology | Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof |
| WO2021252952A1 (en) * | 2020-06-11 | 2021-12-16 | Sangamo Therapeutics, Inc. | Methods and compositions for expressing phenylalanine hydroxylase |
| JP2023532864A (ja) * | 2020-06-30 | 2023-08-01 | ザ ユニバーシティー コート オブ ザ ユニバーシティー オブ エジンバラ | 導入遺伝子発現系 |
| IL300263A (en) | 2020-08-07 | 2023-03-01 | Spacecraft Seven Llc | Plakophilin-2 (PKP2) gene therapy using an AAV vector |
| KR20220035693A (ko) * | 2020-09-14 | 2022-03-22 | 주식회사 제너로스 | 표적화된 유전자 전달을 위한 아데노-부속 바이러스 벡터 |
| MX2023003656A (es) * | 2020-09-29 | 2023-06-22 | Neuexcell Therapeutics Inc | Vector dlx2. |
| US20220186252A1 (en) | 2020-12-16 | 2022-06-16 | Takeda Pharmaceutical Company Limited | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| US20230049217A1 (en) * | 2021-05-21 | 2023-02-16 | Novartis Ag | Compositions and methods for enhancing visual function |
| US20260083848A1 (en) | 2021-11-03 | 2026-03-26 | Viracta Therapeutics, Inc. | Combination of car t-cell therapy with btk inhibitors and methods of use thereof |
| AU2022379949A1 (en) * | 2021-11-04 | 2024-05-02 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| JP2025526237A (ja) | 2022-07-07 | 2025-08-13 | サイエンス コーポレイション | ニューラルインターフェースデバイス |
| US20260124288A1 (en) * | 2022-10-04 | 2026-05-07 | Emergent Product Development Gaithersburg Inc. | Novel vsv virus formulations |
| WO2024226858A1 (en) | 2023-04-26 | 2024-10-31 | Juno Therapeutics, Inc. | Methods for viral vector manufacturing |
| WO2026003069A1 (en) * | 2024-06-25 | 2026-01-02 | Asgard Therapeutics Ab | Constructs and vectors for reprogramming cells to cdc1 cells, compositions and methods thereof |
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| US4452773A (en) | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4795698A (en) | 1985-10-04 | 1989-01-03 | Immunicon Corporation | Magnetic-polymer particles |
| ES2067018T3 (es) | 1988-12-28 | 1995-03-16 | Stefan Miltenyi | Procedimiento y materiales para la separacion en alto gradiente magnetico de materiales biologicos. |
| US5200084A (en) | 1990-09-26 | 1993-04-06 | Immunicon Corporation | Apparatus and methods for magnetic separation |
| WO1992008796A1 (en) | 1990-11-13 | 1992-05-29 | Immunex Corporation | Bifunctional selectable fusion genes |
| AU6953394A (en) | 1993-05-21 | 1994-12-20 | Targeted Genetics Corporation | Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene |
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| KR20160002030A (ko) * | 2014-06-30 | 2016-01-07 | 성지산업 주식회사 | 도플러 센서를 이용한 대상체 감지 방법 및 장치 |
| CN113736828A (zh) | 2014-11-05 | 2021-12-03 | 朱诺治疗学股份有限公司 | 用于转导及细胞处理的方法 |
-
2016
- 2016-01-11 MA MA041346A patent/MA41346A/fr unknown
- 2016-01-12 BR BR112017014917A patent/BR112017014917A2/pt not_active Application Discontinuation
- 2016-01-12 EP EP16703392.7A patent/EP3245292B1/en active Active
- 2016-01-12 SG SG11201705692SA patent/SG11201705692SA/en unknown
- 2016-01-12 CA CA2973483A patent/CA2973483A1/en active Pending
- 2016-01-12 US US14/994,114 patent/US10363269B2/en active Active
- 2016-01-12 WO PCT/US2016/013109 patent/WO2016115177A1/en not_active Ceased
- 2016-01-12 MX MX2017009113A patent/MX391694B/es unknown
- 2016-01-12 KR KR1020177022738A patent/KR102554374B1/ko active Active
- 2016-01-12 ES ES16703392T patent/ES2877367T3/es active Active
- 2016-01-12 MY MYPI2017001032A patent/MY187559A/en unknown
- 2016-01-12 CN CN201680015106.6A patent/CN107429260B/zh active Active
- 2016-01-12 AU AU2016206868A patent/AU2016206868B2/en active Active
- 2016-01-12 JP JP2017536779A patent/JP6868560B2/ja active Active
- 2016-01-12 RU RU2017126975A patent/RU2734594C2/ru active
-
2017
- 2017-07-10 IL IL253399A patent/IL253399B2/en unknown
- 2017-07-12 SA SA517381912A patent/SA517381912B1/ar unknown
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