JP2018502583A5 - - Google Patents
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- JP2018502583A5 JP2018502583A5 JP2017536779A JP2017536779A JP2018502583A5 JP 2018502583 A5 JP2018502583 A5 JP 2018502583A5 JP 2017536779 A JP2017536779 A JP 2017536779A JP 2017536779 A JP2017536779 A JP 2017536779A JP 2018502583 A5 JP2018502583 A5 JP 2018502583A5
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- Prior art keywords
- variant
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562102569P | 2015-01-12 | 2015-01-12 | |
| US62/102,569 | 2015-01-12 | ||
| PCT/US2016/013109 WO2016115177A1 (en) | 2015-01-12 | 2016-01-12 | Modified hepatitis post-transcriptional regulatory elements |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018502583A JP2018502583A (ja) | 2018-02-01 |
| JP2018502583A5 true JP2018502583A5 (enExample) | 2019-02-21 |
| JP6868560B2 JP6868560B2 (ja) | 2021-05-12 |
Family
ID=55310922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017536779A Active JP6868560B2 (ja) | 2015-01-12 | 2016-01-12 | 修飾された肝炎転写後調節エレメント |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10363269B2 (enExample) |
| EP (1) | EP3245292B1 (enExample) |
| JP (1) | JP6868560B2 (enExample) |
| KR (1) | KR102554374B1 (enExample) |
| CN (1) | CN107429260B (enExample) |
| AU (1) | AU2016206868B2 (enExample) |
| BR (1) | BR112017014917A2 (enExample) |
| CA (1) | CA2973483A1 (enExample) |
| ES (1) | ES2877367T3 (enExample) |
| IL (1) | IL253399B2 (enExample) |
| MA (1) | MA41346A (enExample) |
| MX (1) | MX391694B (enExample) |
| MY (1) | MY187559A (enExample) |
| RU (1) | RU2734594C2 (enExample) |
| SA (1) | SA517381912B1 (enExample) |
| SG (1) | SG11201705692SA (enExample) |
| WO (1) | WO2016115177A1 (enExample) |
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| JP6740234B2 (ja) | 2014-11-05 | 2020-08-12 | ジュノー セラピューティクス インコーポレイテッド | 形質導入および細胞プロセシングのための方法 |
| CA2994969A1 (en) | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| KR102673203B1 (ko) | 2016-04-20 | 2024-06-10 | 센트로 데 인베스띠가씨오네스 에너제티까스 메디오암비엔딸레스 와이 테크놀로지까스, 오.에이., 엠.피. | Pklr의 유전자 발현 증강을 위한 조성물 및 방법 |
| KR102712926B1 (ko) | 2016-10-20 | 2024-10-07 | 상가모 테라퓨틱스, 인코포레이티드 | 파브리병의 치료를 위한 방법 및 조성물 |
| CN107058315B (zh) * | 2016-12-08 | 2019-11-08 | 上海优卡迪生物医药科技有限公司 | 敲减人PD-1的siRNA、重组表达CAR-T载体及其构建方法和应用 |
| EP4119552A1 (en) | 2017-02-08 | 2023-01-18 | Dana-Farber Cancer Institute, Inc. | Regulating chimeric antigen receptors |
| WO2019028273A1 (en) * | 2017-08-02 | 2019-02-07 | Dna2.0, Inc. Dba Atum | DNA VECTORS AND ELEMENTS FOR SUSTAINED GENE EXPRESSION IN EUKARYOTIC CELLS |
| CA3076337A1 (en) | 2017-09-19 | 2019-03-28 | Massachusetts Institute Of Technology | Compositions for chimeric antigen receptor t cell therapy and uses thereof |
| AU2018352583B2 (en) | 2017-10-16 | 2025-04-17 | Centro de Investigaciones Energeticas, Medioambientales Y Tecnologicas, O.A., M.P. | Lentiviral vectors for delivery of PKLR to treat Pyruvate Kinase Deficiency |
| US12539316B2 (en) | 2018-04-11 | 2026-02-03 | Spacecraft Seven, Llc | Compositions and methods for stem cell transplant |
| IL278213B2 (en) | 2018-04-27 | 2026-04-01 | Rocket Pharmaceuticals Ltd | A gene therapy vector encoding an e3 ubiquitin protein ligase (park2) and use thereof in treating or inhibiting the onset of parkinson’s disease (pd) |
| IL280465B2 (en) | 2018-07-30 | 2025-03-01 | Centro De Investig Energeticas Medioambientales Y Tecnologicas O A M P | Methods for gene modification of hematopoietic cells |
| SG11202100935TA (en) | 2018-09-28 | 2021-02-25 | Massachusetts Inst Technology | Collagen-localized immunomodulatory molecules and methods thereof |
| CN113423419A (zh) | 2019-01-04 | 2021-09-21 | 桑格摩生物治疗股份有限公司 | 用于治疗法布里病的方法和组合物 |
| KR102947433B1 (ko) | 2019-04-12 | 2026-04-06 | 씨4 테라퓨틱스, 인코포레이티드 | 이카로스 및 아이올로스의 트리시클릭 분해제 |
| CN111825769B (zh) * | 2019-04-16 | 2022-03-25 | 上海科技大学 | 一种泛素化缺失的嵌合抗原受体及其用途 |
| US20230038502A1 (en) | 2019-06-11 | 2023-02-09 | Shire Human Genetic Therapies, Inc. | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| JP2022538974A (ja) | 2019-06-26 | 2022-09-07 | マサチューセッツ インスチテュート オブ テクノロジー | 免疫調節融合タンパク質－金属水酸化物錯体およびその方法 |
| WO2021061648A1 (en) | 2019-09-23 | 2021-04-01 | Massachusetts Institute Of Technology | Methods and compositions for stimulation of endogenous t cell responses |
| WO2021081280A1 (en) | 2019-10-23 | 2021-04-29 | Shire Human Genetic Therapies, Inc. | Adeno-associated virus vectors based gene therapy for hereditary angioedema |
| US11896619B2 (en) | 2020-03-10 | 2024-02-13 | Massachusetts Institute Of Technology | Compositions and methods for immunotherapy of NPM1c-positive cancer |
| IL296242A (en) | 2020-03-10 | 2022-11-01 | Massachusetts Inst Technology | Methods for generating engineered memory-like nk cells and compositions thereof |
| DE102020111571A1 (de) * | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| DE102020106710A1 (de) | 2020-03-11 | 2021-09-16 | Immatics US, Inc. | Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren |
| JP2023523314A (ja) | 2020-04-27 | 2023-06-02 | ジュノー セラピューティクス インコーポレイテッド | ポリエチレンイミン－デオキシリボ核酸複合体のサイズおよび活性の安定化 |
| US20210340524A1 (en) | 2020-05-01 | 2021-11-04 | Massachusetts Institute Of Technology | Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof |
| US12433954B2 (en) | 2020-05-01 | 2025-10-07 | Massachusetts Institute Of Technology | Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs |
| WO2021252952A1 (en) * | 2020-06-11 | 2021-12-16 | Sangamo Therapeutics, Inc. | Methods and compositions for expressing phenylalanine hydroxylase |
| MX2023000124A (es) * | 2020-06-30 | 2023-03-08 | Univ Court Univ Of Edinburgh | Sistema de expresion de transgenes. |
| WO2022032226A1 (en) | 2020-08-07 | 2022-02-10 | Spacecraft Seven, Llc | Plakophilin-2 (pkp2) gene therapy using aav vector |
| KR20220035693A (ko) * | 2020-09-14 | 2022-03-22 | 주식회사 제너로스 | 표적화된 유전자 전달을 위한 아데노-부속 바이러스 벡터 |
| CA3197320A1 (en) * | 2020-09-29 | 2022-04-07 | NeuExcell Therapeutics Inc. | Dlx2 vector |
| MX2023003655A (es) | 2020-09-29 | 2023-06-22 | Neuexcell Therapeutics Inc | Vector neurod1. |
| EP4263614A1 (en) | 2020-12-16 | 2023-10-25 | Takeda Pharmaceutical Company Limited | Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein |
| US20230049217A1 (en) * | 2021-05-21 | 2023-02-16 | Novartis Ag | Compositions and methods for enhancing visual function |
| US20260083848A1 (en) | 2021-11-03 | 2026-03-26 | Viracta Therapeutics, Inc. | Combination of car t-cell therapy with btk inhibitors and methods of use thereof |
| AU2022379949A1 (en) * | 2021-11-04 | 2024-05-02 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| WO2024010916A1 (en) | 2022-07-07 | 2024-01-11 | Science Corporation | Neural interface device |
| EP4598572A1 (en) * | 2022-10-04 | 2025-08-13 | Emergent Product Development Gaithersburg Inc. | Novel vsv virus formulations |
| WO2024226858A1 (en) | 2023-04-26 | 2024-10-31 | Juno Therapeutics, Inc. | Methods for viral vector manufacturing |
| WO2026003067A1 (en) * | 2024-06-25 | 2026-01-02 | Asgard Therapeutics Ab | Transcription factors and reprogramming modulators for reprogramming cells to cdc1 cells, compositions and methods thereof |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
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| KR20160002030A (ko) * | 2014-06-30 | 2016-01-07 | 성지산업 주식회사 | 도플러 센서를 이용한 대상체 감지 방법 및 장치 |
| JP6740234B2 (ja) | 2014-11-05 | 2020-08-12 | ジュノー セラピューティクス インコーポレイテッド | 形質導入および細胞プロセシングのための方法 |
-
2016
- 2016-01-11 MA MA041346A patent/MA41346A/fr unknown
- 2016-01-12 ES ES16703392T patent/ES2877367T3/es active Active
- 2016-01-12 AU AU2016206868A patent/AU2016206868B2/en not_active Ceased
- 2016-01-12 CA CA2973483A patent/CA2973483A1/en active Pending
- 2016-01-12 SG SG11201705692SA patent/SG11201705692SA/en unknown
- 2016-01-12 JP JP2017536779A patent/JP6868560B2/ja active Active
- 2016-01-12 WO PCT/US2016/013109 patent/WO2016115177A1/en not_active Ceased
- 2016-01-12 MY MYPI2017001032A patent/MY187559A/en unknown
- 2016-01-12 BR BR112017014917A patent/BR112017014917A2/pt not_active Application Discontinuation
- 2016-01-12 EP EP16703392.7A patent/EP3245292B1/en active Active
- 2016-01-12 CN CN201680015106.6A patent/CN107429260B/zh active Active
- 2016-01-12 US US14/994,114 patent/US10363269B2/en active Active
- 2016-01-12 KR KR1020177022738A patent/KR102554374B1/ko active Active
- 2016-01-12 RU RU2017126975A patent/RU2734594C2/ru active
- 2016-01-12 MX MX2017009113A patent/MX391694B/es unknown
-
2017
- 2017-07-10 IL IL253399A patent/IL253399B2/en unknown
- 2017-07-12 SA SA517381912A patent/SA517381912B1/ar unknown
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