AU2016206868B2 - Modified hepatitis post-transcriptional regulatory elements - Google Patents

Modified hepatitis post-transcriptional regulatory elements Download PDF

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AU2016206868B2
AU2016206868B2 AU2016206868A AU2016206868A AU2016206868B2 AU 2016206868 B2 AU2016206868 B2 AU 2016206868B2 AU 2016206868 A AU2016206868 A AU 2016206868A AU 2016206868 A AU2016206868 A AU 2016206868A AU 2016206868 B2 AU2016206868 B2 AU 2016206868B2
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seq
gene
variant
nucleotides
sequence
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AU2016206868A1 (en
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Semih U. Tareen
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Juno Therapeutics Inc
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Juno Therapeutics Inc
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
    • A61K40/4211—CD19 or B4
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10041—Use of virus, viral particle or viral elements as a vector
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    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE

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  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2016206868A 2015-01-12 2016-01-12 Modified hepatitis post-transcriptional regulatory elements Ceased AU2016206868B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562102569P 2015-01-12 2015-01-12
US62/102,569 2015-01-12
PCT/US2016/013109 WO2016115177A1 (en) 2015-01-12 2016-01-12 Modified hepatitis post-transcriptional regulatory elements

Publications (2)

Publication Number Publication Date
AU2016206868A1 AU2016206868A1 (en) 2017-07-27
AU2016206868B2 true AU2016206868B2 (en) 2022-03-17

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AU2016206868A Ceased AU2016206868B2 (en) 2015-01-12 2016-01-12 Modified hepatitis post-transcriptional regulatory elements

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US (1) US10363269B2 (enExample)
EP (1) EP3245292B1 (enExample)
JP (1) JP6868560B2 (enExample)
KR (1) KR102554374B1 (enExample)
CN (1) CN107429260B (enExample)
AU (1) AU2016206868B2 (enExample)
BR (1) BR112017014917A2 (enExample)
CA (1) CA2973483A1 (enExample)
ES (1) ES2877367T3 (enExample)
IL (1) IL253399B2 (enExample)
MA (1) MA41346A (enExample)
MX (1) MX391694B (enExample)
MY (1) MY187559A (enExample)
RU (1) RU2734594C2 (enExample)
SA (1) SA517381912B1 (enExample)
SG (1) SG11201705692SA (enExample)
WO (1) WO2016115177A1 (enExample)

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