ES2877367T3 - Elementos reguladores postranscripcionales de hepatitis modificados - Google Patents

Elementos reguladores postranscripcionales de hepatitis modificados Download PDF

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ES2877367T3
ES2877367T3 ES16703392T ES16703392T ES2877367T3 ES 2877367 T3 ES2877367 T3 ES 2877367T3 ES 16703392 T ES16703392 T ES 16703392T ES 16703392 T ES16703392 T ES 16703392T ES 2877367 T3 ES2877367 T3 ES 2877367T3
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gene
seq
variant
cases
nucleotides
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Semih Tareen
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Juno Therapeutics Inc
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Juno Therapeutics Inc
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/15Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • A61K40/421Immunoglobulin superfamily
    • A61K40/4211CD19 or B4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10041Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/48Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE

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  • Cell Biology (AREA)
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  • Hematology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ES16703392T 2015-01-12 2016-01-12 Elementos reguladores postranscripcionales de hepatitis modificados Active ES2877367T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562102569P 2015-01-12 2015-01-12
PCT/US2016/013109 WO2016115177A1 (en) 2015-01-12 2016-01-12 Modified hepatitis post-transcriptional regulatory elements

Publications (1)

Publication Number Publication Date
ES2877367T3 true ES2877367T3 (es) 2021-11-16

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ES16703392T Active ES2877367T3 (es) 2015-01-12 2016-01-12 Elementos reguladores postranscripcionales de hepatitis modificados

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US (1) US10363269B2 (enExample)
EP (1) EP3245292B1 (enExample)
JP (1) JP6868560B2 (enExample)
KR (1) KR102554374B1 (enExample)
CN (1) CN107429260B (enExample)
AU (1) AU2016206868B2 (enExample)
BR (1) BR112017014917A2 (enExample)
CA (1) CA2973483A1 (enExample)
ES (1) ES2877367T3 (enExample)
IL (1) IL253399B2 (enExample)
MA (1) MA41346A (enExample)
MX (1) MX391694B (enExample)
MY (1) MY187559A (enExample)
RU (1) RU2734594C2 (enExample)
SA (1) SA517381912B1 (enExample)
SG (1) SG11201705692SA (enExample)
WO (1) WO2016115177A1 (enExample)

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