JP2018086274A5 - - Google Patents
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- JP2018086274A5 JP2018086274A5 JP2017254812A JP2017254812A JP2018086274A5 JP 2018086274 A5 JP2018086274 A5 JP 2018086274A5 JP 2017254812 A JP2017254812 A JP 2017254812A JP 2017254812 A JP2017254812 A JP 2017254812A JP 2018086274 A5 JP2018086274 A5 JP 2018086274A5
- Authority
- JP
- Japan
- Prior art keywords
- rpe
- cell preparation
- cells
- rpe cell
- macular degeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 210000004027 cell Anatomy 0.000 claims 29
- 238000002360 preparation method Methods 0.000 claims 17
- 238000000034 method Methods 0.000 claims 11
- 208000002780 macular degeneration Diseases 0.000 claims 10
- 208000035719 Maculopathy Diseases 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 230000019612 pigmentation Effects 0.000 claims 4
- 239000000725 suspension Substances 0.000 claims 4
- 101000729271 Homo sapiens Retinoid isomerohydrolase Proteins 0.000 claims 3
- 102100031176 Retinoid isomerohydrolase Human genes 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 201000007737 Retinal degeneration Diseases 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 230000004258 retinal degeneration Effects 0.000 claims 2
- 239000002356 single layer Substances 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 238000002054 transplantation Methods 0.000 claims 2
- 108050002823 Bestrophin Proteins 0.000 claims 1
- 102000012304 Bestrophin Human genes 0.000 claims 1
- 101001078886 Homo sapiens Retinaldehyde-binding protein 1 Proteins 0.000 claims 1
- 101000713575 Homo sapiens Tubulin beta-3 chain Proteins 0.000 claims 1
- 102000008730 Nestin Human genes 0.000 claims 1
- 108010088225 Nestin Proteins 0.000 claims 1
- 102000007354 PAX6 Transcription Factor Human genes 0.000 claims 1
- 101150081664 PAX6 gene Proteins 0.000 claims 1
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 claims 1
- 102100028001 Retinaldehyde-binding protein 1 Human genes 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 102100036790 Tubulin beta-3 chain Human genes 0.000 claims 1
- 208000001309 degenerative myopia Diseases 0.000 claims 1
- 230000004340 degenerative myopia Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 101150087532 mitF gene Proteins 0.000 claims 1
- 210000005055 nestin Anatomy 0.000 claims 1
- 108090000102 pigment epithelium-derived factor Proteins 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53896404P | 2004-01-23 | 2004-01-23 | |
| US60/538,964 | 2004-01-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016152133A Division JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Division JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018086274A JP2018086274A (ja) | 2018-06-07 |
| JP2018086274A5 true JP2018086274A5 (enExample) | 2018-11-29 |
Family
ID=34807248
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
| JP2017254812A Ceased JP2018086274A (ja) | 2004-01-23 | 2017-12-28 | 網膜変性疾患治療のための改良された様式 |
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US7736896B2 (enExample) |
| EP (8) | EP2438814A3 (enExample) |
| JP (10) | JP2007522131A (enExample) |
| KR (3) | KR101398356B1 (enExample) |
| CN (3) | CN1968608B (enExample) |
| AU (6) | AU2005207042B2 (enExample) |
| BR (1) | BRPI0507074A (enExample) |
| CA (2) | CA2937099A1 (enExample) |
| ES (1) | ES2721174T3 (enExample) |
| HK (2) | HK1216068A1 (enExample) |
| IL (3) | IL177015B (enExample) |
| MX (4) | MX375065B (enExample) |
| NZ (1) | NZ548929A (enExample) |
| SG (4) | SG188122A1 (enExample) |
| WO (1) | WO2005070011A2 (enExample) |
Families Citing this family (71)
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| US8043614B2 (en) | 2004-03-09 | 2011-10-25 | Ahlfors Jan-Eric W | Autogenic living scaffolds and living tissue matrices: methods and uses thereof |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| CA2937099A1 (en) * | 2004-01-23 | 2005-08-04 | Astellas Institute For Regenerative Medicine | Improved modalities for the treatment of degenerative diseases of the retina |
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| CN1966080B (zh) * | 2005-11-17 | 2011-06-08 | 李凌松 | 一种治疗老年痴呆症、帕金森病的神经干细胞注射液 |
| US7541186B2 (en) * | 2006-02-22 | 2009-06-02 | University Of Washington | Method of generating human retinal progenitors from embryonic stem cells |
| EP2029724A4 (en) | 2006-05-03 | 2010-03-24 | Advanced Cell Tech Inc | DERIVATION FROM EMBRYONAL STEM CELLS AND EMBRYO-DERIVED CELLS |
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| CA2684460C (en) * | 2007-04-18 | 2017-01-03 | Hadasit Medical Research Services & Development Limited | Stem cell-derived retinal pigment epithelial cells |
| EP2607477B1 (en) | 2007-05-03 | 2020-09-23 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
| EP2209888B1 (en) * | 2007-10-12 | 2019-12-04 | Astellas Institute for Regenerative Medicine | Improved methods of producing rpe cells and compositions of rpe cells |
| AU2015201435B2 (en) * | 2007-10-12 | 2017-02-02 | Astellas Institute For Regenerative Medicine | Improved methods of producing RPE cells and compositions of RPE cells |
| EP2279247B1 (en) * | 2008-04-22 | 2019-01-02 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| EP3553170B1 (en) | 2009-08-24 | 2024-02-14 | Wisconsin Alumni Research Foundation | Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same |
| IL281453B (en) * | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| AU2011279250B2 (en) | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| EP3875599B1 (en) | 2010-07-23 | 2024-12-11 | Astellas Institute for Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| JP2012231786A (ja) * | 2011-04-18 | 2012-11-29 | Kyushu Univ | 標的遺伝子の発現変化による食品機能成分及び医薬品感受性評価方法 |
| WO2012149468A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
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| EP3636286A1 (en) | 2011-05-18 | 2020-04-15 | The Regents of The University of California | Compositions and methods for treating retinal diseases |
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| RU2730937C1 (ru) * | 2019-11-01 | 2020-08-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Миндрава России) | Способ трансплантации клеток ретинального пигментного эпителия (РПЭ), дифференцированных из индуцированных плюрипотентных стволовых клеток человека, при атрофии ретинального пигментного эпителия |
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