JP2018086274A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018086274A5 JP2018086274A5 JP2017254812A JP2017254812A JP2018086274A5 JP 2018086274 A5 JP2018086274 A5 JP 2018086274A5 JP 2017254812 A JP2017254812 A JP 2017254812A JP 2017254812 A JP2017254812 A JP 2017254812A JP 2018086274 A5 JP2018086274 A5 JP 2018086274A5
- Authority
- JP
- Japan
- Prior art keywords
- rpe
- cell preparation
- cells
- rpe cell
- macular degeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 210000004027 cell Anatomy 0.000 claims 29
- 238000002360 preparation method Methods 0.000 claims 17
- 238000000034 method Methods 0.000 claims 11
- 208000002780 macular degeneration Diseases 0.000 claims 10
- 208000035719 Maculopathy Diseases 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 230000019612 pigmentation Effects 0.000 claims 4
- 239000000725 suspension Substances 0.000 claims 4
- 101000729271 Homo sapiens Retinoid isomerohydrolase Proteins 0.000 claims 3
- 102100031176 Retinoid isomerohydrolase Human genes 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 201000007737 Retinal degeneration Diseases 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 230000004258 retinal degeneration Effects 0.000 claims 2
- 239000002356 single layer Substances 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 238000002054 transplantation Methods 0.000 claims 2
- 108050002823 Bestrophin Proteins 0.000 claims 1
- 102000012304 Bestrophin Human genes 0.000 claims 1
- 101001078886 Homo sapiens Retinaldehyde-binding protein 1 Proteins 0.000 claims 1
- 101000713575 Homo sapiens Tubulin beta-3 chain Proteins 0.000 claims 1
- 102000008730 Nestin Human genes 0.000 claims 1
- 108010088225 Nestin Proteins 0.000 claims 1
- 102000007354 PAX6 Transcription Factor Human genes 0.000 claims 1
- 101150081664 PAX6 gene Proteins 0.000 claims 1
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 claims 1
- 102100028001 Retinaldehyde-binding protein 1 Human genes 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 102100036790 Tubulin beta-3 chain Human genes 0.000 claims 1
- 208000001309 degenerative myopia Diseases 0.000 claims 1
- 230000004340 degenerative myopia Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 101150087532 mitF gene Proteins 0.000 claims 1
- 210000005055 nestin Anatomy 0.000 claims 1
- 108090000102 pigment epithelium-derived factor Proteins 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53896404P | 2004-01-23 | 2004-01-23 | |
| US60/538,964 | 2004-01-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016152133A Division JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Division JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018086274A JP2018086274A (ja) | 2018-06-07 |
| JP2018086274A5 true JP2018086274A5 (enExample) | 2018-11-29 |
Family
ID=34807248
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
| JP2017254812A Ceased JP2018086274A (ja) | 2004-01-23 | 2017-12-28 | 網膜変性疾患治療のための改良された様式 |
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US7736896B2 (enExample) |
| EP (8) | EP1708575A4 (enExample) |
| JP (10) | JP2007522131A (enExample) |
| KR (3) | KR20130025953A (enExample) |
| CN (3) | CN102204930B (enExample) |
| AU (6) | AU2005207042B2 (enExample) |
| BR (1) | BRPI0507074A (enExample) |
| CA (2) | CA2555370C (enExample) |
| ES (1) | ES2721174T3 (enExample) |
| HK (2) | HK1216068A1 (enExample) |
| IL (3) | IL177015B (enExample) |
| MX (4) | MX375061B (enExample) |
| NZ (1) | NZ548929A (enExample) |
| SG (4) | SG155236A1 (enExample) |
| WO (1) | WO2005070011A2 (enExample) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8043614B2 (en) * | 2004-03-09 | 2011-10-25 | Ahlfors Jan-Eric W | Autogenic living scaffolds and living tissue matrices: methods and uses thereof |
| AU2005207042B2 (en) * | 2004-01-23 | 2010-09-09 | President And Fellows Of Harvard College | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| EP2960328A1 (en) | 2004-11-04 | 2015-12-30 | Ocata Therapeutics, Inc. | Derivation of embryonic stem cells |
| CN1966080B (zh) * | 2005-11-17 | 2011-06-08 | 李凌松 | 一种治疗老年痴呆症、帕金森病的神经干细胞注射液 |
| US7541186B2 (en) * | 2006-02-22 | 2009-06-02 | University Of Washington | Method of generating human retinal progenitors from embryonic stem cells |
| EP2029724A4 (en) | 2006-05-03 | 2010-03-24 | Advanced Cell Tech Inc | DERIVATION FROM EMBRYONAL STEM CELLS AND EMBRYO-DERIVED CELLS |
| JP5441099B2 (ja) * | 2007-01-18 | 2014-03-12 | 独立行政法人理化学研究所 | 視細胞への分化誘導方法 |
| WO2008103462A2 (en) | 2007-02-23 | 2008-08-28 | Advanced Cell Technology, Inc. | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
| US8956866B2 (en) * | 2007-04-18 | 2015-02-17 | Hadasit Medical Research Services And Development Ltd. | Retinal pigment epithelial cells differentiated from embryonic stem cells with nicotinamide and activin A |
| US20100291042A1 (en) | 2007-05-03 | 2010-11-18 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
| AU2015201435B2 (en) * | 2007-10-12 | 2017-02-02 | Astellas Institute For Regenerative Medicine | Improved methods of producing RPE cells and compositions of RPE cells |
| CN104946591A (zh) * | 2007-10-12 | 2015-09-30 | 奥卡塔治疗公司 | 制备rpe 细胞和rpe 细胞的组合物的改良方法 |
| WO2009132156A1 (en) * | 2008-04-22 | 2009-10-29 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| US9328328B2 (en) * | 2009-08-24 | 2016-05-03 | Wisconsin Alumni Research Foundation | Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same |
| EP2501802A4 (en) | 2009-11-17 | 2013-08-21 | Advanced Cell Tech Inc | METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS |
| AU2011279250B2 (en) | 2010-07-12 | 2014-12-04 | California Institute Of Technology | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| AU2011280878B2 (en) | 2010-07-23 | 2016-06-16 | Astellas Institute For Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| JP2012231786A (ja) * | 2011-04-18 | 2012-11-29 | Kyushu Univ | 標的遺伝子の発現変化による食品機能成分及び医薬品感受性評価方法 |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| WO2012149468A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| CA2835825C (en) | 2011-05-13 | 2021-03-23 | Minoru S.H. Ko | Use of zscan4 and zscan4-dependent genes for direct reprogramming of somatic cells |
| EP2709672B1 (en) | 2011-05-18 | 2019-12-18 | The Regents of The University of California | Compositions and methods for treating retinal diseases |
| WO2013015835A1 (en) | 2011-07-22 | 2013-01-31 | Seven Networks, Inc. | Mobile application traffic optimization |
| CN103007355B (zh) * | 2011-09-20 | 2014-08-13 | 同济大学 | 一种水凝胶-纳米纤维膜及其制备方法和用途 |
| IL287381B2 (en) * | 2011-11-14 | 2024-04-01 | Astellas Inst For Regenerative Medicine | Pharmaceutical preparations of human rpe cells and uses thereof |
| RS57886B1 (sr) | 2011-11-30 | 2019-01-31 | Astellas Inst For Regenerative Medicine | Mezenhimalne stromalne ćelije i primene vezane za njih |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| BR112014019328A8 (pt) * | 2012-02-17 | 2017-07-11 | The Schepens Eye Res Institute | Perfil de fenótipo de células progenitoras retinais humanas |
| US10519422B2 (en) | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| CA2876499C (en) | 2012-07-12 | 2021-10-26 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CN113088481A (zh) * | 2012-08-24 | 2021-07-09 | 独立行政法人理化学研究所 | 用于生产视网膜色素上皮细胞片层的方法 |
| KR102527507B1 (ko) * | 2013-03-15 | 2023-04-28 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 만능 줄기 세포로부터 제조된 광수용기 및 광수용기 전구체 |
| US11241460B2 (en) | 2013-03-15 | 2022-02-08 | Astellas Institute For Regenerative Medicine | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
| US10072242B2 (en) * | 2013-03-25 | 2018-09-11 | Foundation For Biomedical Research And Innovation At Kobe | Cell sorting method |
| EP2796545A1 (en) * | 2013-04-26 | 2014-10-29 | Université Pierre et Marie Curie (Paris 6) | Methods for obtaining retinal progenitors, retinal pigmented epithelial cells and neural retinal cells |
| JP6470286B2 (ja) | 2013-11-27 | 2019-02-13 | 京都府公立大学法人 | ラミニンの角膜内皮細胞培養への応用 |
| BR112016012129A8 (pt) | 2013-12-11 | 2020-05-12 | Pfizer Ltd | métodos para produção, expansão e purificação de células epiteliais do pigmento da retina, composição farmacêutica e uso das células |
| BR112017008805A2 (pt) | 2014-10-31 | 2017-12-19 | Kyoto Prefectural Public Univ Corp | tratamento de córnea usando laminina |
| US11918630B2 (en) | 2014-10-31 | 2024-03-05 | Kyoto Prefectural Public University Corporation | Treatment of retina and nerve using laminin |
| ES2980659T3 (es) | 2015-03-23 | 2024-10-02 | Astellas Inst For Regenerative Medicine | Ensayos mejorados de potencia de células de epitelio pigmentario retiniano (EPR) humano y progenitores de fotorreceptores |
| SG10201913250SA (en) | 2015-08-18 | 2020-03-30 | Astellas Inst For Regenerative Medicine | Clinical formulations |
| ES2922475T3 (es) | 2015-09-08 | 2022-09-15 | Sumitomo Pharma Co Ltd | Método para producir células epiteliales pigmentarias de la retina |
| CA2997763A1 (en) | 2015-09-08 | 2017-03-16 | Cellular Dynamics International, Inc. | Macs-based purification of stem cell-derived retinal pigment epithelium |
| KR102781602B1 (ko) | 2015-09-08 | 2025-03-18 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 임상 등급 망막 색소 상피 세포의 재현성 있는 분화 방법 |
| ES2862676T3 (es) | 2015-10-20 | 2021-10-07 | Fujifilm Cellular Dynamics Inc | Producción de células precursoras hematopoyéticas multilinaje mediante programación genética |
| CN106609257B (zh) * | 2015-10-22 | 2020-04-10 | 同济大学 | 高效分离体外诱导的rpe细胞和rpc的方法 |
| CN106609263B (zh) * | 2015-10-22 | 2020-04-07 | 同济大学 | 高效诱导多能干细胞向视网膜色素上皮细胞分化的方法 |
| CN106609256B (zh) * | 2015-10-22 | 2020-04-07 | 同济大学 | 体外诱导人胚胎干细胞分化为视网膜色素上皮细胞的方法 |
| CN106609255B (zh) * | 2015-10-22 | 2019-11-05 | 同济大学 | 含pj34和视网膜色素上皮细胞的细胞悬液及其应用 |
| CN106282096A (zh) * | 2016-10-19 | 2017-01-04 | 江苏艾尔康生物医药科技有限公司 | 一种人类视网膜色素上皮细胞层的分离培养方法 |
| CN110573610B (zh) | 2017-03-08 | 2025-01-28 | 住友制药株式会社 | 视网膜色素上皮细胞的制备方法 |
| CA3056653A1 (en) * | 2017-03-16 | 2018-09-20 | Lineage Cell Therapeutics, Inc. | Methods for the treatment of retinal diseases |
| AU2018254442B2 (en) | 2017-04-18 | 2024-03-28 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| US20200277571A1 (en) * | 2017-09-14 | 2020-09-03 | Riken | Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter |
| AU2018369975B2 (en) | 2017-11-15 | 2022-05-19 | Friedrich Miescher Institute For Biomedical Research | Primate retinal pigment epithelium cell-specific promoter |
| CN108029638B (zh) * | 2017-12-04 | 2020-04-21 | 四川省人民医院 | 一种视网膜色素变性疾病动物模型的构建方法及应用 |
| WO2019177936A1 (en) * | 2018-03-12 | 2019-09-19 | Nxcell Inc. | Method for generating multiple cellular products from single pluripotent cell source |
| US12533382B2 (en) | 2019-04-26 | 2026-01-27 | Riken | Composite including neural retina, retinal pigment epithelial cells, and hydrogel, and method for producing same |
| BR112022006644A2 (pt) * | 2019-10-30 | 2022-07-12 | Astellas Inst For Regenerative Medicine | Métodos para a produção de células epiteliais de pigmento da retina |
| RU2730937C1 (ru) * | 2019-11-01 | 2020-08-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Миндрава России) | Способ трансплантации клеток ретинального пигментного эпителия (РПЭ), дифференцированных из индуцированных плюрипотентных стволовых клеток человека, при атрофии ретинального пигментного эпителия |
| WO2022191216A1 (ja) | 2021-03-09 | 2022-09-15 | 国立研究開発法人理化学研究所 | 低免疫原性網膜色素上皮細胞の製造方法 |
| WO2023090427A1 (ja) | 2021-11-19 | 2023-05-25 | 国立研究開発法人理化学研究所 | シート状網膜組織の製造方法 |
| WO2023176906A1 (ja) | 2022-03-16 | 2023-09-21 | 住友ファーマ株式会社 | 移植用媒体 |
| KR20250007548A (ko) | 2022-04-15 | 2025-01-14 | 아스펜 뉴로사이언스 인코포레이티드 | 세포의 분화 상태를 분류하는 방법 및 관련 분화된 세포 조성물 |
| JPWO2024172043A1 (enExample) | 2023-02-14 | 2024-08-22 | ||
| CN121057811A (zh) | 2023-03-29 | 2025-12-02 | 瑞克生乐有限公司 | 视网膜组织的制造方法 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0700429B1 (en) | 1993-04-30 | 2000-10-11 | PHOTOGENESIS Incorporated | Retinal pigment epithelium transplantation |
| US6878544B2 (en) | 1996-04-19 | 2005-04-12 | Neurotech Sa | Retinal cell lines with extended life-span and their applications |
| US20040086494A1 (en) | 1996-10-07 | 2004-05-06 | John Constance Mary | Immune privileged cells for delivery of proteins and peptides |
| AU5734998A (en) | 1997-01-10 | 1998-08-03 | Life Technologies, Inc. | Embryonic stem cell serum replacement |
| US6331406B1 (en) * | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
| NZ505459A (en) | 1998-01-02 | 2003-07-25 | Titan Pharmaceuticals Inc | Use of pigmented retinal epithelial cells for creation of an immune privilege site |
| AU2884499A (en) | 1998-03-02 | 1999-09-20 | Compucyte Corp. | Selective cell analysis |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| EP1230342A4 (en) | 1999-10-28 | 2003-04-09 | Univ Massachusetts | GYNOGENETIC OR ANDROGENETIC PRODUCTION OF PLURIPOTENT CELLS AND CELL LINES AND THEIR USE IN THE PRODUCTION OF DIFFERENTIATED CELLS AND TISSUES |
| JP3454206B2 (ja) * | 1999-11-10 | 2003-10-06 | 三菱電機株式会社 | 雑音抑圧装置及び雑音抑圧方法 |
| US20020035735A1 (en) | 2000-01-07 | 2002-03-21 | Gerald Schatten | Clonal propagation of primate offspring by embryo splitting |
| US6602711B1 (en) | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| US20030084471A1 (en) * | 2000-03-16 | 2003-05-01 | David Beach | Methods and compositions for RNA interference |
| US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
| CA2456008A1 (en) | 2000-08-19 | 2002-02-28 | Axordia Limited | Stem cell differentiation |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| AU2002236495B2 (en) | 2000-11-29 | 2006-05-11 | Allergan, Inc. | Intraocular implants for preventing transplant rejection in the eye |
| DE10108412B4 (de) * | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| JP2004531262A (ja) | 2001-05-15 | 2004-10-14 | ラッパポート ファミリー インスチチュート フォア リサーチ イン ザ メディカル サイエンシズ | ヒト胚性幹細胞由来インスリン産生細胞 |
| GB2393734B (en) | 2001-07-12 | 2005-07-27 | Geron Corp | Cells of the cardiomyocyte lineage produced from human pluripotent stem cells |
| MXPA04005010A (es) * | 2001-11-26 | 2005-04-08 | Advanced Cell Tech Inc | METODO PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS METODOS PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS HUMANOS REPROGRAMADOS Y CELULAS DEL TALLO HUMANAS AUTOLOGAS E ISOGENICAS. |
| AU2002366641A1 (en) | 2001-12-11 | 2003-06-23 | Fibrogen, Inc. | Methods for inhibiting ocular processes |
| JP5578388B2 (ja) | 2002-04-18 | 2014-08-27 | オプコ ファーマシューティカルズ、エルエルシー | 中枢神経システム及び／若しくは眼の細胞及び組織中の遺伝子の特異的阻害のための手段と方法 |
| US7422736B2 (en) * | 2002-07-26 | 2008-09-09 | Food Industry Research And Development Institute | Somatic pluripotent cells |
| JP2006501848A (ja) | 2002-10-04 | 2006-01-19 | ティシュテク，インク． | 網膜色素上皮細胞の羊膜での培養及び移植 |
| CN100593351C (zh) * | 2002-10-08 | 2010-03-03 | 日本电气株式会社 | 阵列装置以及便携式终端 |
| WO2004045374A2 (en) | 2002-11-14 | 2004-06-03 | Ethicon Endo-Surgery, Inc. | Methods and devices for detecting tissue cells |
| CA2518677A1 (en) | 2003-03-03 | 2004-12-09 | Nagaoka & Co., Ltd. | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
| AU2005207042B2 (en) * | 2004-01-23 | 2010-09-09 | President And Fellows Of Harvard College | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| EP2960328A1 (en) | 2004-11-04 | 2015-12-30 | Ocata Therapeutics, Inc. | Derivation of embryonic stem cells |
| DE602006016735D1 (de) | 2005-02-11 | 2010-10-21 | Agency Science Tech & Res | Verfahren zur proliferation von stammzellen |
| KR100832592B1 (ko) | 2006-08-17 | 2008-05-27 | 박현숙 | 폴리머 막을 이용한 줄기세포와 피더세포의 공배양방법 |
| US8956866B2 (en) | 2007-04-18 | 2015-02-17 | Hadasit Medical Research Services And Development Ltd. | Retinal pigment epithelial cells differentiated from embryonic stem cells with nicotinamide and activin A |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| CN104946591A (zh) | 2007-10-12 | 2015-09-30 | 奥卡塔治疗公司 | 制备rpe 细胞和rpe 细胞的组合物的改良方法 |
| HU0700675D0 (en) | 2007-10-15 | 2007-12-28 | Mta Tamogatott Kutatohelyek Ir | Method for monitoring stem cell differentiation |
| US20090233324A1 (en) | 2008-03-11 | 2009-09-17 | Kopf-Sill Anne R | Methods for Diagnosing Cancer Using Samples Collected From A Central Vein Location or an Arterial Location |
| US8652123B2 (en) | 2008-09-02 | 2014-02-18 | Geoffrey C. GURTNER | Methods and devices for improving the appearance of tissue |
| EP2501802A4 (en) | 2009-11-17 | 2013-08-21 | Advanced Cell Tech Inc | METHOD FOR PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS FROM HUMAN RPE CELLS |
| AU2011280878B2 (en) | 2010-07-23 | 2016-06-16 | Astellas Institute For Regenerative Medicine | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| WO2012149484A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| IL287381B2 (en) | 2011-11-14 | 2024-04-01 | Astellas Inst For Regenerative Medicine | Pharmaceutical preparations of human rpe cells and uses thereof |
| US9850463B2 (en) | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
| ES2688019T3 (es) | 2012-06-05 | 2018-10-30 | The Regents Of The University Of California | Métodos y composiciones para la producción acelerada de células epiteliales pigmentadas retinianas a partir de células pluripotentes |
-
2005
- 2005-01-24 AU AU2005207042A patent/AU2005207042B2/en not_active Expired
- 2005-01-24 ES ES11183613T patent/ES2721174T3/es not_active Expired - Lifetime
- 2005-01-24 WO PCT/US2005/002273 patent/WO2005070011A2/en not_active Ceased
- 2005-01-24 MX MX2015009311A patent/MX375061B/es unknown
- 2005-01-24 CN CN201110132307.3A patent/CN102204930B/zh not_active Expired - Lifetime
- 2005-01-24 EP EP05711960A patent/EP1708575A4/en not_active Withdrawn
- 2005-01-24 MX MX2014001634A patent/MX375065B/es unknown
- 2005-01-24 NZ NZ548929A patent/NZ548929A/en not_active IP Right Cessation
- 2005-01-24 CN CN2005800073590A patent/CN1968608B/zh not_active Expired - Lifetime
- 2005-01-24 EP EP22188897.7A patent/EP4248751A3/en active Pending
- 2005-01-24 KR KR1020137002345A patent/KR20130025953A/ko not_active Ceased
- 2005-01-24 EP EP11183611A patent/EP2438815A3/en not_active Withdrawn
- 2005-01-24 CA CA2555370A patent/CA2555370C/en not_active Expired - Lifetime
- 2005-01-24 CN CN201410645051.XA patent/CN104434979A/zh active Pending
- 2005-01-24 SG SG200905546-8A patent/SG155236A1/en unknown
- 2005-01-24 SG SG10201606441SA patent/SG10201606441SA/en unknown
- 2005-01-24 EP EP23176538.9A patent/EP4248752A3/en not_active Withdrawn
- 2005-01-24 BR BRPI0507074-0A patent/BRPI0507074A/pt not_active Application Discontinuation
- 2005-01-24 JP JP2006551392A patent/JP2007522131A/ja active Pending
- 2005-01-24 EP EP11183613.6A patent/EP2438816B1/en not_active Expired - Lifetime
- 2005-01-24 CA CA2937099A patent/CA2937099A1/en active Pending
- 2005-01-24 EP EP23176537.1A patent/EP4269561A3/en not_active Withdrawn
- 2005-01-24 SG SG10201912182UA patent/SG10201912182UA/en unknown
- 2005-01-24 SG SG2013009170A patent/SG188122A1/en unknown
- 2005-01-24 EP EP15248003.4A patent/EP2929782A1/en not_active Ceased
- 2005-01-24 EP EP11183610A patent/EP2438814A3/en not_active Withdrawn
- 2005-01-24 KR KR1020067016837A patent/KR101258292B1/ko not_active Expired - Lifetime
- 2005-01-24 KR KR1020127008183A patent/KR101398356B1/ko not_active Expired - Lifetime
- 2005-07-20 US US11/186,720 patent/US7736896B2/en not_active Expired - Lifetime
-
2006
- 2006-07-20 IL IL177015A patent/IL177015B/en active IP Right Grant
- 2006-07-21 MX MX2011006096A patent/MX343606B/es unknown
- 2006-07-21 MX MX2020009456A patent/MX2020009456A/es unknown
- 2006-07-21 US US11/490,953 patent/US7795025B2/en active Active
-
2007
- 2007-04-04 HK HK16104134.1A patent/HK1216068A1/en unknown
-
2010
- 2010-05-18 US US12/781,929 patent/US9040770B2/en not_active Expired - Lifetime
- 2010-08-17 US US12/857,866 patent/US9649340B2/en not_active Expired - Lifetime
- 2010-12-09 AU AU2010249263A patent/AU2010249263B2/en not_active Expired
-
2012
- 2012-02-27 JP JP2012040491A patent/JP2012148085A/ja active Pending
-
2013
- 2013-03-21 AU AU2013201791A patent/AU2013201791B2/en not_active Expired
-
2014
- 2014-01-30 JP JP2014016135A patent/JP2014079650A/ja not_active Ceased
-
2015
- 2015-02-12 JP JP2015025500A patent/JP2015096556A/ja not_active Ceased
- 2015-04-21 US US14/692,191 patent/US9730962B2/en not_active Expired - Fee Related
- 2015-08-31 HK HK15108469.8A patent/HK1207821A1/xx unknown
-
2016
- 2016-08-02 JP JP2016152133A patent/JP2016195862A/ja not_active Withdrawn
- 2016-11-15 AU AU2016259323A patent/AU2016259323B2/en not_active Expired
-
2017
- 2017-07-18 US US15/653,472 patent/US20180064761A1/en not_active Abandoned
- 2017-12-28 JP JP2017254812A patent/JP2018086274A/ja not_active Ceased
-
2019
- 2019-01-25 AU AU2019200513A patent/AU2019200513A1/en not_active Abandoned
- 2019-06-05 IL IL267126A patent/IL267126B/en unknown
- 2019-09-19 JP JP2019170249A patent/JP2019217356A/ja active Pending
-
2020
- 2020-06-18 JP JP2020105536A patent/JP2020146575A/ja not_active Ceased
-
2021
- 2021-01-29 AU AU2021200601A patent/AU2021200601A1/en not_active Abandoned
-
2022
- 2022-03-07 IL IL291162A patent/IL291162A/en unknown
- 2022-08-03 JP JP2022124147A patent/JP2022153630A/ja active Pending
-
2024
- 2024-01-22 JP JP2024007584A patent/JP2024038460A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015096556A5 (enExample) | ||
| JP2022153630A5 (enExample) | ||
| JP2020146575A5 (enExample) | ||
| Chichagova et al. | Cellular regeneration strategies for macular degeneration: past, present and future | |
| JP2022079484A5 (enExample) | ||
| JP2014239904A5 (enExample) | ||
| JP2018522593A5 (enExample) | ||
| WO2016162747A3 (en) | Methods and compositions for producing stem cell derived dopaminergic cells for use in treatment of neurodegenerative diseases | |
| JP2017035113A5 (enExample) | ||
| IL256587A (en) | Methods for the formation of epithelial pigment cells of the retina sorted from pluripotent stem cells | |
| JP2015521054A5 (enExample) | ||
| JP2010285434A5 (enExample) | ||
| WO2018098365A3 (en) | Compositions and methods for tcr reprogramming using fusion proteins | |
| Li et al. | Human induced pluripotent stem cells in Parkinson's disease: A novel cell source of cell therapy and disease modeling | |
| MY184796A (en) | Method for manufacturing ciliary marginal zone-like structure | |
| WO2016061232A3 (en) | Multiplexed shrnas and uses thereof | |
| WO2014193716A3 (en) | Capsid-modified, raav3 vector compositions and uses in gene therapy of human liver cancer | |
| JP2015159895A5 (enExample) | ||
| PH12014502508A1 (en) | hUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS | |
| AR087471A1 (es) | Metodos de tratamiento de enfermedades degenerativas de la retina | |
| JP2018502576A5 (enExample) | ||
| MX2021009554A (es) | Produccion de virus en cultivos celulares. | |
| EP4471130A3 (en) | New immunoregulatory cells and methods for their production | |
| WO2014183033A3 (en) | G-csf for use in treating or preventing a disease associated with aging in a patient, for administration with a stem-cell containing composition and/or an electromagnetic signal | |
| SG11201806177QA (en) | Transplant material for treatment of heart disease |