JP2018086274A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018086274A5 JP2018086274A5 JP2017254812A JP2017254812A JP2018086274A5 JP 2018086274 A5 JP2018086274 A5 JP 2018086274A5 JP 2017254812 A JP2017254812 A JP 2017254812A JP 2017254812 A JP2017254812 A JP 2017254812A JP 2018086274 A5 JP2018086274 A5 JP 2018086274A5
- Authority
- JP
- Japan
- Prior art keywords
- rpe
- cell preparation
- cells
- rpe cell
- macular degeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 210000004027 cell Anatomy 0.000 claims 29
- 238000002360 preparation method Methods 0.000 claims 17
- 238000000034 method Methods 0.000 claims 11
- 208000002780 macular degeneration Diseases 0.000 claims 10
- 208000035719 Maculopathy Diseases 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 230000019612 pigmentation Effects 0.000 claims 4
- 239000000725 suspension Substances 0.000 claims 4
- 101000729271 Homo sapiens Retinoid isomerohydrolase Proteins 0.000 claims 3
- 102100031176 Retinoid isomerohydrolase Human genes 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 201000007737 Retinal degeneration Diseases 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 230000004258 retinal degeneration Effects 0.000 claims 2
- 239000002356 single layer Substances 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 238000002054 transplantation Methods 0.000 claims 2
- 108050002823 Bestrophin Proteins 0.000 claims 1
- 102000012304 Bestrophin Human genes 0.000 claims 1
- 101001078886 Homo sapiens Retinaldehyde-binding protein 1 Proteins 0.000 claims 1
- 101000713575 Homo sapiens Tubulin beta-3 chain Proteins 0.000 claims 1
- 102000008730 Nestin Human genes 0.000 claims 1
- 108010088225 Nestin Proteins 0.000 claims 1
- 102000007354 PAX6 Transcription Factor Human genes 0.000 claims 1
- 101150081664 PAX6 gene Proteins 0.000 claims 1
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 claims 1
- 102100028001 Retinaldehyde-binding protein 1 Human genes 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 102100036790 Tubulin beta-3 chain Human genes 0.000 claims 1
- 208000001309 degenerative myopia Diseases 0.000 claims 1
- 230000004340 degenerative myopia Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 101150087532 mitF gene Proteins 0.000 claims 1
- 210000005055 nestin Anatomy 0.000 claims 1
- 108090000102 pigment epithelium-derived factor Proteins 0.000 claims 1
- 230000002062 proliferating effect Effects 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53896404P | 2004-01-23 | 2004-01-23 | |
| US60/538,964 | 2004-01-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016152133A Division JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Division JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018086274A JP2018086274A (ja) | 2018-06-07 |
| JP2018086274A5 true JP2018086274A5 (enExample) | 2018-11-29 |
Family
ID=34807248
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
| JP2017254812A Ceased JP2018086274A (ja) | 2004-01-23 | 2017-12-28 | 網膜変性疾患治療のための改良された様式 |
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006551392A Pending JP2007522131A (ja) | 2004-01-23 | 2005-01-24 | 網膜変性疾患治療のための改良された様式 |
| JP2012040491A Pending JP2012148085A (ja) | 2004-01-23 | 2012-02-27 | 網膜変性疾患治療のための改良された様式 |
| JP2014016135A Ceased JP2014079650A (ja) | 2004-01-23 | 2014-01-30 | 網膜変性疾患治療のための改良された様式 |
| JP2015025500A Ceased JP2015096556A (ja) | 2004-01-23 | 2015-02-12 | 網膜変性疾患治療のための改良された様式 |
| JP2016152133A Withdrawn JP2016195862A (ja) | 2004-01-23 | 2016-08-02 | 網膜変性疾患治療のための改良された様式 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019170249A Pending JP2019217356A (ja) | 2004-01-23 | 2019-09-19 | 網膜変性疾患治療のための改良された様式 |
| JP2020105536A Ceased JP2020146575A (ja) | 2004-01-23 | 2020-06-18 | 網膜変性疾患治療のための改良された様式 |
| JP2022124147A Pending JP2022153630A (ja) | 2004-01-23 | 2022-08-03 | 網膜変性疾患治療のための改良された様式 |
| JP2024007584A Pending JP2024038460A (ja) | 2004-01-23 | 2024-01-22 | 網膜変性疾患治療のための改良された様式 |
Country Status (15)
| Country | Link |
|---|---|
| US (6) | US7736896B2 (enExample) |
| EP (8) | EP4248752A3 (enExample) |
| JP (10) | JP2007522131A (enExample) |
| KR (3) | KR101398356B1 (enExample) |
| CN (3) | CN1968608B (enExample) |
| AU (6) | AU2005207042B2 (enExample) |
| BR (1) | BRPI0507074A (enExample) |
| CA (2) | CA2937099A1 (enExample) |
| ES (1) | ES2721174T3 (enExample) |
| HK (2) | HK1216068A1 (enExample) |
| IL (3) | IL177015B (enExample) |
| MX (4) | MX375061B (enExample) |
| NZ (1) | NZ548929A (enExample) |
| SG (4) | SG188122A1 (enExample) |
| WO (1) | WO2005070011A2 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8043614B2 (en) | 2004-03-09 | 2011-10-25 | Ahlfors Jan-Eric W | Autogenic living scaffolds and living tissue matrices: methods and uses thereof |
| SG188122A1 (en) * | 2004-01-23 | 2013-03-28 | Advanced Cell Tech Inc | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| CN1966080B (zh) * | 2005-11-17 | 2011-06-08 | 李凌松 | 一种治疗老年痴呆症、帕金森病的神经干细胞注射液 |
| US7541186B2 (en) * | 2006-02-22 | 2009-06-02 | University Of Washington | Method of generating human retinal progenitors from embryonic stem cells |
| KR101602951B1 (ko) | 2006-05-03 | 2016-03-14 | 오카타 세라퓨틱스, 인크. | 배아 줄기 세포 및 배-유도 세포의 유도 |
| JP5441099B2 (ja) * | 2007-01-18 | 2014-03-12 | 独立行政法人理化学研究所 | 視細胞への分化誘導方法 |
| EP3190178A1 (en) | 2007-02-23 | 2017-07-12 | Astellas Institute for Regenerative Medicine | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
| ES2530370T5 (es) * | 2007-04-18 | 2018-05-28 | Hadasit Medical Research Services & Development Limited | Células del epitelio pigmentario de la retina derivadas de células madre |
| EP2607477B1 (en) | 2007-05-03 | 2020-09-23 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
| ES2764473T3 (es) * | 2007-10-12 | 2020-06-03 | Astellas Inst For Regenerative Medicine | Métodos mejorados para producir células RPE y composiciones de células RPE |
| AU2015201435B2 (en) * | 2007-10-12 | 2017-02-02 | Astellas Institute For Regenerative Medicine | Improved methods of producing RPE cells and compositions of RPE cells |
| WO2009132156A1 (en) * | 2008-04-22 | 2009-10-29 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| CA3066806C (en) | 2009-08-24 | 2023-03-07 | David M. Gamm | Substantially pure human retinal progenitor, forebrain progenitor, and retinal pigment epithelium cell cultures and methods of making the same |
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| EP4245370A3 (en) | 2010-07-12 | 2023-11-29 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| ES2874953T3 (es) | 2010-07-23 | 2021-11-05 | Astellas Inst For Regenerative Medicine | Métodos para la detección de subpoblaciones raras de células y composiciones muy purificadas de células |
| JP2012231786A (ja) * | 2011-04-18 | 2012-11-29 | Kyushu Univ | 標的遺伝子の発現変化による食品機能成分及び医薬品感受性評価方法 |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| JP6189829B2 (ja) | 2011-05-13 | 2017-08-30 | ザ・ユナイテッド・ステイツ・オブ・アメリカ・アズ・リプリゼンティド・バイ・ザ・セクレタリー・フォー・ザ・デパートメント・オブ・ヘルス・アンド・ヒューマン・サービシズ | Zscan4とzscan4依存性遺伝子を利用した体細胞の直接的な再プログラム化 |
| JP6223963B2 (ja) * | 2011-05-18 | 2017-11-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 網膜疾患を処置するための組成物および方法 |
| WO2013015835A1 (en) | 2011-07-22 | 2013-01-31 | Seven Networks, Inc. | Mobile application traffic optimization |
| CN103007355B (zh) * | 2011-09-20 | 2014-08-13 | 同济大学 | 一种水凝胶-纳米纤维膜及其制备方法和用途 |
| CA2855941A1 (en) * | 2011-11-14 | 2013-05-23 | Advanced Cell Technology, Inc. | Pharmaceutical preparations of human rpe cells and uses thereof |
| KR102108245B1 (ko) | 2011-11-30 | 2020-05-08 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| EP3492586B1 (en) * | 2012-02-17 | 2024-04-17 | Schepens Eye Research Institute | Phenotype profile of human retinal progenitor cells |
| US10519422B2 (en) | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| US11033586B2 (en) * | 2012-08-24 | 2021-06-15 | Riken | Method for producing retinal pigment epithelial cell sheet |
| AU2014233403B2 (en) * | 2013-03-15 | 2019-08-01 | Astellas Institute For Regenerative Medicine | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
| US11241460B2 (en) | 2013-03-15 | 2022-02-08 | Astellas Institute For Regenerative Medicine | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
| WO2014157257A1 (ja) * | 2013-03-25 | 2014-10-02 | 公益財団法人先端医療振興財団 | 細胞の選別方法 |
| EP2796545A1 (en) * | 2013-04-26 | 2014-10-29 | Université Pierre et Marie Curie (Paris 6) | Methods for obtaining retinal progenitors, retinal pigmented epithelial cells and neural retinal cells |
| RU2704984C1 (ru) | 2013-11-27 | 2019-11-01 | Киото Прифекчурал Паблик Юниверсити Корпорэйшн | Применение ламинина в культуре клеток эндотелия роговицы |
| EP3080248A1 (en) | 2013-12-11 | 2016-10-19 | Pfizer Limited | Method for producing retinal pigment epithelial cells |
| WO2016067629A1 (ja) * | 2014-10-31 | 2016-05-06 | 京都府公立大学法人 | ラミニンによる網膜および神経の新規治療 |
| CN113559246A (zh) | 2014-10-31 | 2021-10-29 | 京都府公立大学法人 | 使用层粘连蛋白的新的角膜的治疗 |
| EP4343331A3 (en) | 2015-03-23 | 2024-06-19 | Astellas Institute for Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| AU2016308818B2 (en) | 2015-08-18 | 2022-04-21 | Astellas Institute For Regenerative Medicine | Clinical formulations |
| ES2970537T3 (es) | 2015-09-08 | 2024-05-29 | Us Health | Método para la diferenciación reproducible de células epiteliales del pigmento retiniano de calidad clínica |
| ES2922475T3 (es) | 2015-09-08 | 2022-09-15 | Sumitomo Pharma Co Ltd | Método para producir células epiteliales pigmentarias de la retina |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| US10865381B2 (en) | 2015-10-20 | 2020-12-15 | FUJIFILM Cellular Dynamics, Inc. | Multi-lineage hematopoietic precursor cell production by genetic programming |
| CN106609256B (zh) * | 2015-10-22 | 2020-04-07 | 同济大学 | 体外诱导人胚胎干细胞分化为视网膜色素上皮细胞的方法 |
| CN106609255B (zh) * | 2015-10-22 | 2019-11-05 | 同济大学 | 含pj34和视网膜色素上皮细胞的细胞悬液及其应用 |
| CN106609257B (zh) * | 2015-10-22 | 2020-04-10 | 同济大学 | 高效分离体外诱导的rpe细胞和rpc的方法 |
| CN106609263B (zh) * | 2015-10-22 | 2020-04-07 | 同济大学 | 高效诱导多能干细胞向视网膜色素上皮细胞分化的方法 |
| CN106282096A (zh) * | 2016-10-19 | 2017-01-04 | 江苏艾尔康生物医药科技有限公司 | 一种人类视网膜色素上皮细胞层的分离培养方法 |
| CA3055706A1 (en) | 2017-03-08 | 2018-09-13 | Sumitomo Dainippon Pharma Co., Ltd. | Method for producing retinal pigment epithelial cells |
| CN110913874A (zh) * | 2017-03-16 | 2020-03-24 | 谱系细胞疗法公司 | 用于测量视网膜疾病疗法的疗效的方法 |
| MX2019011897A (es) | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Celulas efectoras inmunitarias especificas de antigenos. |
| US20200277571A1 (en) * | 2017-09-14 | 2020-09-03 | Riken | Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter |
| CR20200210A (es) | 2017-11-15 | 2020-09-23 | Friedrich Miescher Institute For Biomedical Res | Promotor especìfico de las cèlulas del epitelio pigmentario retinal en primates |
| CN108029638B (zh) * | 2017-12-04 | 2020-04-21 | 四川省人民医院 | 一种视网膜色素变性疾病动物模型的构建方法及应用 |
| US11946069B2 (en) | 2018-03-12 | 2024-04-02 | RxCell, Inc. | Method for generating multiple cellular products from single pluripotent cell source |
| TWI820330B (zh) * | 2019-04-26 | 2023-11-01 | 國立研究開發法人理化學研究所 | 包含神經視網膜與視網膜色素上皮細胞與水凝膠之複合體及其製造方法 |
| MX2022005134A (es) | 2019-10-30 | 2022-05-30 | Astellas Inst For Regenerative Medicine | Metodos para producir celulas del epitelio pigmentario retiniano. |
| RU2730937C1 (ru) * | 2019-11-01 | 2020-08-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Миндрава России) | Способ трансплантации клеток ретинального пигментного эпителия (РПЭ), дифференцированных из индуцированных плюрипотентных стволовых клеток человека, при атрофии ретинального пигментного эпителия |
| EP4306634A4 (en) | 2021-03-09 | 2025-03-26 | Riken | METHOD FOR PRODUCING HYPOIMMUNOGENIC RETINAL PIGMENT EPITHELIAL CELLS |
| US20250019652A1 (en) | 2021-11-19 | 2025-01-16 | Riken | Production method for sheet-like retinal tissue |
| US20250188412A1 (en) | 2022-03-16 | 2025-06-12 | Sumitomo Pharma Co., Ltd. | Transplantation medium |
| WO2023201361A1 (en) | 2022-04-15 | 2023-10-19 | Aspen Neuroscience, Inc. | Methods of classifying the differentiation state of cells and related compositions of differentiated cells |
| WO2024172043A1 (ja) | 2023-02-14 | 2024-08-22 | 住友ファーマ株式会社 | 網膜色素上皮裂孔の治療薬 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69329556D1 (de) | 1993-04-30 | 2000-11-16 | Photogenesis Inc | Transplantation des retinalen pigmentepithels |
| US6878544B2 (en) | 1996-04-19 | 2005-04-12 | Neurotech Sa | Retinal cell lines with extended life-span and their applications |
| US20040086494A1 (en) * | 1996-10-07 | 2004-05-06 | John Constance Mary | Immune privileged cells for delivery of proteins and peptides |
| EP0986635A4 (en) | 1997-01-10 | 2001-11-07 | Life Technologies Inc | SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS |
| US6331406B1 (en) * | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
| WO1999034834A1 (en) | 1998-01-02 | 1999-07-15 | Titan Pharmaceuticals, Inc. | Use of pigmented retinal epithelial cells for creation of an immune privilege site |
| CA2321203A1 (en) | 1998-03-02 | 1999-09-10 | Compucyte Corp. | Selective cell analysis |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| JP2003514516A (ja) | 1999-10-28 | 2003-04-22 | ユニバーシティ オブ マサチューセッツ | 多能性細胞と細胞株の雌性発生的または雄性発生的産生および分化した細胞と組織を産生するためのその使用 |
| JP3454206B2 (ja) * | 1999-11-10 | 2003-10-06 | 三菱電機株式会社 | 雑音抑圧装置及び雑音抑圧方法 |
| WO2001050848A2 (en) * | 2000-01-07 | 2001-07-19 | Oregon Health And Science University | Clonal propagation of primate offspring by embryo splitting |
| US6602711B1 (en) * | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| US20030084471A1 (en) * | 2000-03-16 | 2003-05-01 | David Beach | Methods and compositions for RNA interference |
| US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
| US20040053869A1 (en) | 2000-08-19 | 2004-03-18 | Peter Andrews | Stem cell differentiation |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| US6699493B2 (en) | 2000-11-29 | 2004-03-02 | Oculex Pharmaceuticals, Inc. | Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor |
| DE10108412B4 (de) * | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| EP1393066A4 (en) | 2001-05-15 | 2006-01-25 | Rappaport Family Inst For Res | INSULIN-PRODUCING CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS |
| IL159580A0 (en) | 2001-07-12 | 2004-06-01 | Geron Corp | Cells of the cardiomyocyte lineage produced from human pluripotent stem cells |
| WO2003046141A2 (en) * | 2001-11-26 | 2003-06-05 | Advanced Cell Technology, Inc. | Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells |
| AU2002366641A1 (en) | 2001-12-11 | 2003-06-23 | Fibrogen, Inc. | Methods for inhibiting ocular processes |
| CA2482904A1 (en) | 2002-04-18 | 2003-10-23 | Lynkeus Biotech Gmbh | Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification |
| US7422736B2 (en) | 2002-07-26 | 2008-09-09 | Food Industry Research And Development Institute | Somatic pluripotent cells |
| US7824671B2 (en) * | 2002-10-04 | 2010-11-02 | Tissuetech, Inc. | Retinal pigment epithelial cell cultures on amniotic membrane and transplantation |
| JP4348706B2 (ja) * | 2002-10-08 | 2009-10-21 | 日本電気株式会社 | アレイ装置および携帯端末 |
| AU2003302020B2 (en) * | 2002-11-14 | 2008-01-31 | Ethicon Endo-Surgery, Inc. | Methods and devices for detecting tissue cells |
| EP1599730A2 (en) * | 2003-03-03 | 2005-11-30 | Kouyama, Yoshihisa | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
| US7794704B2 (en) * | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| SG188122A1 (en) | 2004-01-23 | 2013-03-28 | Advanced Cell Tech Inc | Improved modalities for the treatment of degenerative diseases of the retina |
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| CN102220280A (zh) | 2005-02-11 | 2011-10-19 | 新加坡科技研究局 | 增殖干细胞的方法 |
| KR100832592B1 (ko) | 2006-08-17 | 2008-05-27 | 박현숙 | 폴리머 막을 이용한 줄기세포와 피더세포의 공배양방법 |
| ES2530370T5 (es) * | 2007-04-18 | 2018-05-28 | Hadasit Medical Research Services & Development Limited | Células del epitelio pigmentario de la retina derivadas de células madre |
| JP2008307007A (ja) * | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| ES2764473T3 (es) | 2007-10-12 | 2020-06-03 | Astellas Inst For Regenerative Medicine | Métodos mejorados para producir células RPE y composiciones de células RPE |
| HU0700675D0 (en) | 2007-10-15 | 2007-12-28 | Mta Tamogatott Kutatohelyek Ir | Method for monitoring stem cell differentiation |
| US20090233324A1 (en) * | 2008-03-11 | 2009-09-17 | Kopf-Sill Anne R | Methods for Diagnosing Cancer Using Samples Collected From A Central Vein Location or an Arterial Location |
| US8652123B2 (en) * | 2008-09-02 | 2014-02-18 | Geoffrey C. GURTNER | Methods and devices for improving the appearance of tissue |
| WO2011063005A2 (en) * | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| ES2874953T3 (es) | 2010-07-23 | 2021-11-05 | Astellas Inst For Regenerative Medicine | Métodos para la detección de subpoblaciones raras de células y composiciones muy purificadas de células |
| EP2702135B1 (en) | 2011-04-29 | 2019-04-17 | University of Southern California | Method of cryopreservation of stem cell-derived retinal pigment epithelial cells on polymeric substrate |
| CA2855941A1 (en) * | 2011-11-14 | 2013-05-23 | Advanced Cell Technology, Inc. | Pharmaceutical preparations of human rpe cells and uses thereof |
| US9850463B2 (en) | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
| ES2688019T3 (es) | 2012-06-05 | 2018-10-30 | The Regents Of The University Of California | Métodos y composiciones para la producción acelerada de células epiteliales pigmentadas retinianas a partir de células pluripotentes |
-
2005
- 2005-01-24 SG SG2013009170A patent/SG188122A1/en unknown
- 2005-01-24 KR KR1020127008183A patent/KR101398356B1/ko not_active Expired - Lifetime
- 2005-01-24 CN CN2005800073590A patent/CN1968608B/zh not_active Expired - Lifetime
- 2005-01-24 CA CA2937099A patent/CA2937099A1/en active Pending
- 2005-01-24 SG SG10201606441SA patent/SG10201606441SA/en unknown
- 2005-01-24 SG SG200905546-8A patent/SG155236A1/en unknown
- 2005-01-24 EP EP23176538.9A patent/EP4248752A3/en not_active Withdrawn
- 2005-01-24 NZ NZ548929A patent/NZ548929A/en not_active IP Right Cessation
- 2005-01-24 EP EP11183611A patent/EP2438815A3/en not_active Withdrawn
- 2005-01-24 EP EP22188897.7A patent/EP4248751A3/en active Pending
- 2005-01-24 MX MX2015009311A patent/MX375061B/es unknown
- 2005-01-24 SG SG10201912182UA patent/SG10201912182UA/en unknown
- 2005-01-24 CN CN201110132307.3A patent/CN102204930B/zh not_active Expired - Lifetime
- 2005-01-24 EP EP23176537.1A patent/EP4269561A3/en not_active Withdrawn
- 2005-01-24 EP EP11183610A patent/EP2438814A3/en not_active Withdrawn
- 2005-01-24 CN CN201410645051.XA patent/CN104434979A/zh active Pending
- 2005-01-24 JP JP2006551392A patent/JP2007522131A/ja active Pending
- 2005-01-24 BR BRPI0507074-0A patent/BRPI0507074A/pt not_active Application Discontinuation
- 2005-01-24 WO PCT/US2005/002273 patent/WO2005070011A2/en not_active Ceased
- 2005-01-24 EP EP05711960A patent/EP1708575A4/en not_active Withdrawn
- 2005-01-24 KR KR1020067016837A patent/KR101258292B1/ko not_active Expired - Lifetime
- 2005-01-24 ES ES11183613T patent/ES2721174T3/es not_active Expired - Lifetime
- 2005-01-24 AU AU2005207042A patent/AU2005207042B2/en not_active Expired
- 2005-01-24 EP EP15248003.4A patent/EP2929782A1/en not_active Ceased
- 2005-01-24 MX MX2014001634A patent/MX375065B/es unknown
- 2005-01-24 CA CA2555370A patent/CA2555370C/en not_active Expired - Lifetime
- 2005-01-24 KR KR1020137002345A patent/KR20130025953A/ko not_active Ceased
- 2005-01-24 EP EP11183613.6A patent/EP2438816B1/en not_active Expired - Lifetime
- 2005-07-20 US US11/186,720 patent/US7736896B2/en active Active
-
2006
- 2006-07-20 IL IL177015A patent/IL177015B/en active IP Right Grant
- 2006-07-21 MX MX2011006096A patent/MX343606B/es unknown
- 2006-07-21 US US11/490,953 patent/US7795025B2/en active Active
- 2006-07-21 MX MX2020009456A patent/MX2020009456A/es unknown
-
2007
- 2007-04-04 HK HK16104134.1A patent/HK1216068A1/en unknown
-
2010
- 2010-05-18 US US12/781,929 patent/US9040770B2/en active Active
- 2010-08-17 US US12/857,866 patent/US9649340B2/en not_active Expired - Lifetime
- 2010-12-09 AU AU2010249263A patent/AU2010249263B2/en not_active Expired
-
2012
- 2012-02-27 JP JP2012040491A patent/JP2012148085A/ja active Pending
-
2013
- 2013-03-21 AU AU2013201791A patent/AU2013201791B2/en not_active Expired
-
2014
- 2014-01-30 JP JP2014016135A patent/JP2014079650A/ja not_active Ceased
-
2015
- 2015-02-12 JP JP2015025500A patent/JP2015096556A/ja not_active Ceased
- 2015-04-21 US US14/692,191 patent/US9730962B2/en not_active Expired - Fee Related
- 2015-08-31 HK HK15108469.8A patent/HK1207821A1/xx unknown
-
2016
- 2016-08-02 JP JP2016152133A patent/JP2016195862A/ja not_active Withdrawn
- 2016-11-15 AU AU2016259323A patent/AU2016259323B2/en not_active Expired
-
2017
- 2017-07-18 US US15/653,472 patent/US20180064761A1/en not_active Abandoned
- 2017-12-28 JP JP2017254812A patent/JP2018086274A/ja not_active Ceased
-
2019
- 2019-01-25 AU AU2019200513A patent/AU2019200513A1/en not_active Abandoned
- 2019-06-05 IL IL267126A patent/IL267126B/en unknown
- 2019-09-19 JP JP2019170249A patent/JP2019217356A/ja active Pending
-
2020
- 2020-06-18 JP JP2020105536A patent/JP2020146575A/ja not_active Ceased
-
2021
- 2021-01-29 AU AU2021200601A patent/AU2021200601A1/en not_active Abandoned
-
2022
- 2022-03-07 IL IL291162A patent/IL291162A/en unknown
- 2022-08-03 JP JP2022124147A patent/JP2022153630A/ja active Pending
-
2024
- 2024-01-22 JP JP2024007584A patent/JP2024038460A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018086274A5 (enExample) | ||
| JP2015096556A5 (enExample) | ||
| JP2022153630A5 (enExample) | ||
| JP2020146575A5 (enExample) | ||
| Chichagova et al. | Cellular regeneration strategies for macular degeneration: past, present and future | |
| Wang et al. | Stem/progenitor cell-based transplantation for retinal degeneration: a review of clinical trials | |
| Seiler et al. | Cell replacement and visual restoration by retinal sheet transplants | |
| Carr et al. | Development of human embryonic stem cell therapies for age-related macular degeneration | |
| JP2014239904A5 (enExample) | ||
| JP2018522593A5 (enExample) | ||
| JP2014000094A5 (ja) | 臍帯由来細胞を用いた局部的または散在的脳外傷の改善 | |
| WO2016162747A3 (en) | Methods and compositions for producing stem cell derived dopaminergic cells for use in treatment of neurodegenerative diseases | |
| JP2017035113A5 (enExample) | ||
| FI2780022T4 (fi) | Pharmaceutical preparations of human rpe cells and uses thereof | |
| EP4495133A3 (en) | Methods of isolating t cells having antigenic specificity for a p53 cancer-specific mutation | |
| JP2015521054A5 (enExample) | ||
| Li et al. | Human induced pluripotent stem cells in Parkinson's disease: A novel cell source of cell therapy and disease modeling | |
| JP2016515382A5 (enExample) | ||
| MY184796A (en) | Method for manufacturing ciliary marginal zone-like structure | |
| PH12014502508B1 (en) | hUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS | |
| EP3492597A3 (en) | Capsid-modified, raav3 vector compositions and methods of use in gene therapy of human liver cancer | |
| JP2015159895A5 (enExample) | ||
| AR087471A1 (es) | Metodos de tratamiento de enfermedades degenerativas de la retina | |
| JP2018502576A5 (enExample) | ||
| JP2016501013A5 (enExample) |