WO2019004800A3 - 줄기세포 유래 피부전구세포 배양액 및 이의 제조 방법 - Google Patents

줄기세포 유래 피부전구세포 배양액 및 이의 제조 방법 Download PDF

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WO2019004800A3
WO2019004800A3 PCT/KR2018/007470 KR2018007470W WO2019004800A3 WO 2019004800 A3 WO2019004800 A3 WO 2019004800A3 KR 2018007470 W KR2018007470 W KR 2018007470W WO 2019004800 A3 WO2019004800 A3 WO 2019004800A3
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stem cell
derived skin
skin precursor
culture medium
stem
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PCT/KR2018/007470
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English (en)
French (fr)
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WO2019004800A2 (ko
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유지민
김애리
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주식회사 차바이오텍
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Priority to US16/627,671 priority Critical patent/US11773370B2/en
Priority to SG11201913778VA priority patent/SG11201913778VA/en
Priority to RU2020103760A priority patent/RU2754043C2/ru
Priority to CN201880046020.9A priority patent/CN110869491A/zh
Priority to AU2018290634A priority patent/AU2018290634B2/en
Priority to JP2020500191A priority patent/JP2020525039A/ja
Publication of WO2019004800A2 publication Critical patent/WO2019004800A2/ko
Publication of WO2019004800A3 publication Critical patent/WO2019004800A3/ko

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells

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  • Health & Medical Sciences (AREA)
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  • Wood Science & Technology (AREA)
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  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

줄기세포를 아스코르브산 및 히드로코르티손을 포함하는 분화 배지에서 배양하여 줄기세포 유래 피부전구세포로 분화시키는 단계; 상기 분화된 줄기세포 유래 피부전구세포를 배지에서 배양하여 줄기세포 유래 피부전구세포의 배양물을 생성시키는 단계; 및 상기 줄기세포 유래 피부전구세포의 배양물로부터 줄기세포 유래 피부전구세포 배양액을 회수하는 단계;를 포함하는 줄기세포 유래 피부전구세포 배양액을 제조하는 방법, 상기 방법으로 생산된 줄기세포 유래 피부전구세포 배양액, 및 상기 방법을 포함하는 줄기세포 유래 피부전구세포로부터 단백질을 생산하는 방법을 제공한다.
PCT/KR2018/007470 2017-06-30 2018-07-02 줄기세포 유래 피부전구세포 배양액 및 이의 제조 방법 WO2019004800A2 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US16/627,671 US11773370B2 (en) 2017-06-30 2018-07-02 Stem cell-derived skin precursor cell culture medium and preparation method therefor
SG11201913778VA SG11201913778VA (en) 2017-06-30 2018-07-02 Stem cell-derived skin precursor cell culture medium and preparation method therefor
RU2020103760A RU2754043C2 (ru) 2017-06-30 2018-07-02 Культуральная среда клеток-предшественников кожи, происходящих из стволовых клеток, и способ ее получения
CN201880046020.9A CN110869491A (zh) 2017-06-30 2018-07-02 干细胞来源皮肤前体细胞培养液及其制备方法
AU2018290634A AU2018290634B2 (en) 2017-06-30 2018-07-02 Stem cell-derived skin precursor cell culture medium and preparation method therefor
JP2020500191A JP2020525039A (ja) 2017-06-30 2018-07-02 幹細胞由来の皮膚前駆細胞培養液及びその製造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0083861 2017-06-30
KR1020170083861A KR102100608B1 (ko) 2017-06-30 2017-06-30 줄기세포 유래 피부전구세포 배양액 및 이의 제조 방법

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WO2019004800A2 WO2019004800A2 (ko) 2019-01-03
WO2019004800A3 true WO2019004800A3 (ko) 2019-05-23

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PCT/KR2018/007470 WO2019004800A2 (ko) 2017-06-30 2018-07-02 줄기세포 유래 피부전구세포 배양액 및 이의 제조 방법

Country Status (8)

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US (1) US11773370B2 (ko)
JP (1) JP2020525039A (ko)
KR (1) KR102100608B1 (ko)
CN (1) CN110869491A (ko)
AU (1) AU2018290634B2 (ko)
RU (1) RU2754043C2 (ko)
SG (1) SG11201913778VA (ko)
WO (1) WO2019004800A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102325449B1 (ko) * 2018-09-07 2021-11-12 (주)차바이오텍 다능성 줄기세포 유래 중간엽 줄기세포 직접 분화용 배지, 그를 이용하여 중간엽 줄기세포를 제조하는 방법, 및 그에 의해 제조된 중간엽 줄기세포

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014003319A1 (ko) * 2012-06-26 2014-01-03 Ra Jeong-Chan 고농도의 줄기세포 제조방법
KR101830062B1 (ko) * 2017-06-30 2018-02-20 주식회사 차바이오텍 피부줄기세포 배양액을 포함하는 피부 노화 예방 또는 개선용 조성물 및 이의 용도

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EP2811015B1 (en) 2011-12-01 2020-09-02 R Bio Co., Ltd. Culture-medium composition for rejuvenating stem cells
GB201416006D0 (en) 2014-09-10 2014-10-22 Univ Singapore Organotypic skin model
WO2016061071A1 (en) 2014-10-14 2016-04-21 Cellular Dynamics International, Inc. Generation of keratinocytes from pluripotent stem cells and mantenance of keratinocyte cultures

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WO2014003319A1 (ko) * 2012-06-26 2014-01-03 Ra Jeong-Chan 고농도의 줄기세포 제조방법
KR101830062B1 (ko) * 2017-06-30 2018-02-20 주식회사 차바이오텍 피부줄기세포 배양액을 포함하는 피부 노화 예방 또는 개선용 조성물 및 이의 용도

Non-Patent Citations (6)

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Title
COUTEAUDIER, MATHILDE ET AL.: "Derivation of Keratinocytes from Chicken Embryonic Stem Cells: Establishment and Characterizatoin of Differentiated Proliferative Ceil Populations", STEM CELL RESEARCH, vol. 14, no. 2, 2015, pages 224 - 237, XP029204319 *
NAIR, RENJITH P. ET AL.: "Identification of p63+ Keratinocyte Progenitor Cells in Circulation and Their Matrix-directed Differentiation to Epithelial Cells", STEM CELL RESEARCH & THERAPY, vol. 4, no. 2, 2013, pages 1 - 13, XP021148976, DOI: doi:10.1186/scrt186 *
SHIM, JOONG HYUN ET AL.: "Human Dermal Stem/Progenitor Cell -derived Conditioned Medium Ameliorates Ultraviolet A-induced Damage of Normal Human Dermal Fibroblasts", PLOS ONE, vol. 8, no. 7, 2013, pages 1 - 9, XP055611791 *
SOHN, SU ET AL.: "Anti-aging Properties of Conditioned Media of Epidermal Progenitor Cells Derived from Mesenchymal Stem Cells", DERMATOLOGY AND THERAPY, vol. 8, 2 March 2018 (2018-03-02), pages 229 - 244, XP055611798 *
SOHN. S. ET AL.: "149) The Protective Effects of Stem Cell -derived Epidermal Progenitor Cell -conditioned Media against Oxidative Stress in Human Dermal Fibroblasts", EUROPE SOCIETY OF DERMAL RESEARCH (ESDR) PRESENTATION, 2016 *
YAVARI, K. ET AL.: "Human Umbilical Cord Blood Stem Cells Differentiate into Keratinocytes under in Vitro Conditions and Culturing Differentiated Cells on Bacterial Cellulose Film", INTERNATIONAL JOURNAL OF STEM CELL RESEARCH AND TRANSPLANTATION (SJST, vol. 04, no. 7, 2016, pages 216 - 219, XP055611793 *

Also Published As

Publication number Publication date
KR102100608B1 (ko) 2020-04-14
RU2754043C2 (ru) 2021-08-25
RU2020103760A (ru) 2021-07-30
WO2019004800A2 (ko) 2019-01-03
RU2020103760A3 (ko) 2021-07-30
JP2020525039A (ja) 2020-08-27
SG11201913778VA (en) 2020-01-30
KR20190003241A (ko) 2019-01-09
CN110869491A (zh) 2020-03-06
US20200157500A1 (en) 2020-05-21
US11773370B2 (en) 2023-10-03
AU2018290634A1 (en) 2020-02-06
AU2018290634B2 (en) 2022-02-03

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