GB201416006D0 - Organotypic skin model - Google Patents

Organotypic skin model

Info

Publication number
GB201416006D0
GB201416006D0 GBGB1416006.3A GB201416006A GB201416006D0 GB 201416006 D0 GB201416006 D0 GB 201416006D0 GB 201416006 A GB201416006 A GB 201416006A GB 201416006 D0 GB201416006 D0 GB 201416006D0
Authority
GB
United Kingdom
Prior art keywords
skin model
organotypic skin
organotypic
model
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1416006.3A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National University of Singapore
Original Assignee
National University of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University of Singapore filed Critical National University of Singapore
Priority to GBGB1416006.3A priority Critical patent/GB201416006D0/en
Publication of GB201416006D0 publication Critical patent/GB201416006D0/en
Priority to PCT/SG2015/050302 priority patent/WO2016039687A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
GBGB1416006.3A 2014-09-10 2014-09-10 Organotypic skin model Ceased GB201416006D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1416006.3A GB201416006D0 (en) 2014-09-10 2014-09-10 Organotypic skin model
PCT/SG2015/050302 WO2016039687A1 (en) 2014-09-10 2015-09-04 Organotypic skin model

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1416006.3A GB201416006D0 (en) 2014-09-10 2014-09-10 Organotypic skin model

Publications (1)

Publication Number Publication Date
GB201416006D0 true GB201416006D0 (en) 2014-10-22

Family

ID=51796479

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1416006.3A Ceased GB201416006D0 (en) 2014-09-10 2014-09-10 Organotypic skin model

Country Status (2)

Country Link
GB (1) GB201416006D0 (en)
WO (1) WO2016039687A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201510913D0 (en) * 2015-06-22 2015-08-05 Nat University Of Singapore And Agency For Science Technology And Res Vascularized tissue, skin or mucosa quivalent
EA201792635A1 (en) * 2015-06-25 2018-06-29 Окленд Юнисервисиз Лимитед DEVICE AND METHOD FOR CULTIVATING TISSUES
KR102100608B1 (en) 2017-06-30 2020-04-14 주식회사 차바이오텍 Stem cell-derived epidermal progenitor cell conditioned medium and method for production thereof
CN113166694A (en) * 2018-11-30 2021-07-23 株式会社资生堂 Pigmentation skin model, method for producing same, and method for evaluating factor for treating or preventing skin pigmentation
EP3875580A1 (en) * 2020-03-02 2021-09-08 Centre d'Etude des Cellules Souches (CECS) Methods for preparing keratinocytes
EP3875124A1 (en) * 2020-03-02 2021-09-08 Urgo Recherche Innovation Et Developpement Method for obtaining a pre-vascularised dermo-epidermic tissue
EP3875581A1 (en) * 2020-03-02 2021-09-08 Centre d'Etude des Cellules Souches (CECS) Automated method for preparing keratinocytes
EP3875582A1 (en) * 2020-03-02 2021-09-08 Urgo Recherche Innovation Et Developpement Method for differentiating pluripotent stem cells in fibroblasts of underlying connective tissue of an epithelium
US20230392127A1 (en) * 2020-10-21 2023-12-07 Kangstem Biotech Co., Ltd. Method for construction of atopic dermatitis model by using pluripotent stem cell-derived skin organoid
CN113046300A (en) * 2021-03-19 2021-06-29 上海爱萨尔生物科技有限公司 Culture method for preparing keratinocytes based on differentiation of pluripotent stem cells
CN112980775B (en) * 2021-03-19 2024-01-23 上海爱萨尔生物科技有限公司 Culture solution for preparing keratinocyte based on differentiation of pluripotent stem cells
CN113881625A (en) * 2021-09-14 2022-01-04 广东省科学院健康医学研究所 Cell slice culture additive and application thereof
JP7315184B2 (en) * 2022-02-16 2023-07-26 株式会社コーセー Method for inducing differentiation from pluripotent stem cells to epidermal keratinocytes
CN115161258A (en) * 2022-06-23 2022-10-11 中国药科大学 3D (three-dimensional) horny layer model and construction method and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010048917A1 (en) * 1998-03-09 2001-12-06 Warren Hoeffler Skin equivalent and methods of forming and using same
FR2825370A1 (en) * 2001-05-31 2002-12-06 Inst Nat Sante Rech Med KERATINOCYTES OBTAINED FROM MAMMALIAN EMBRYONIC STEM CELLS
US20050054100A1 (en) * 2003-09-08 2005-03-10 Rennard Stephen I. Methods for fibroblast differentiation
US7413900B2 (en) * 2005-10-31 2008-08-19 President And Fellows Of Harvard College Immortalized fibroblasts
EP2371944A1 (en) * 2010-03-24 2011-10-05 Deutsches Krebsforschungszentrum Scaffold-based organotypic culture fort the long-term cultivation of human epidermal stem-cells

Also Published As

Publication number Publication date
WO2016039687A1 (en) 2016-03-17

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)