JP2018008997A5 - - Google Patents
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- JP2018008997A5 JP2018008997A5 JP2017153176A JP2017153176A JP2018008997A5 JP 2018008997 A5 JP2018008997 A5 JP 2018008997A5 JP 2017153176 A JP2017153176 A JP 2017153176A JP 2017153176 A JP2017153176 A JP 2017153176A JP 2018008997 A5 JP2018008997 A5 JP 2018008997A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- formulation
- pharmaceutical composition
- sodium
- bisoxatin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000008194 pharmaceutical composition Substances 0.000 claims 66
- 239000000203 mixture Substances 0.000 claims 58
- 238000009472 formulation Methods 0.000 claims 35
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 9
- BPKUDUSVDVLOPY-UHFFFAOYSA-N bisoxatin Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C(=O)NC2=CC=CC=C2O1 BPKUDUSVDVLOPY-UHFFFAOYSA-N 0.000 claims 8
- ZCBJDQBSLZREAA-UHFFFAOYSA-N Bisoxatin acetate Chemical compound C1=CC(OC(=O)C)=CC=C1C1(C=2C=CC(OC(C)=O)=CC=2)C(=O)NC2=CC=CC=C2O1 ZCBJDQBSLZREAA-UHFFFAOYSA-N 0.000 claims 7
- 229960002875 bisoxatin Drugs 0.000 claims 7
- 229950009290 bisoxatin acetate Drugs 0.000 claims 7
- 159000000000 sodium salts Chemical class 0.000 claims 7
- YVPYQUNUQOZFHG-UHFFFAOYSA-N amidotrizoic acid Chemical compound CC(=O)NC1=C(I)C(NC(C)=O)=C(I)C(C(O)=O)=C1I YVPYQUNUQOZFHG-UHFFFAOYSA-N 0.000 claims 5
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims 4
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims 4
- 229910001425 magnesium ion Inorganic materials 0.000 claims 4
- 159000000003 magnesium salts Chemical class 0.000 claims 4
- 229910001415 sodium ion Inorganic materials 0.000 claims 4
- 229960005223 diatrizoic acid Drugs 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 2
- 239000002872 contrast media Substances 0.000 claims 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000008141 laxative Substances 0.000 claims 2
- 230000002475 laxative effect Effects 0.000 claims 2
- 229910052938 sodium sulfate Inorganic materials 0.000 claims 2
- 235000011152 sodium sulphate Nutrition 0.000 claims 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 1
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 claims 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 1
- KHOITXIGCFIULA-UHFFFAOYSA-N Alophen Chemical compound C1=CC(OC(=O)C)=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OC(C)=O)C=C1 KHOITXIGCFIULA-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims 1
- 239000004386 Erythritol Substances 0.000 claims 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims 1
- 229930003451 Vitamin B1 Natural products 0.000 claims 1
- 229930003268 Vitamin C Natural products 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 229940022663 acetate Drugs 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims 1
- 125000000129 anionic group Chemical group 0.000 claims 1
- 229910052788 barium Inorganic materials 0.000 claims 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- QEPMPXAUMUWNNO-UHFFFAOYSA-N bis(methylsulfanyl)methyl-trimethylsilane Chemical compound CSC(SC)[Si](C)(C)C QEPMPXAUMUWNNO-UHFFFAOYSA-N 0.000 claims 1
- 229960000503 bisacodyl Drugs 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229960005069 calcium Drugs 0.000 claims 1
- 235000001465 calcium Nutrition 0.000 claims 1
- 229940001468 citrate Drugs 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 230000000112 colonic effect Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000009748 deglutition Effects 0.000 claims 1
- 229960005423 diatrizoate Drugs 0.000 claims 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 1
- 229940009714 erythritol Drugs 0.000 claims 1
- 235000019414 erythritol Nutrition 0.000 claims 1
- 229960000304 folic acid Drugs 0.000 claims 1
- 235000019152 folic acid Nutrition 0.000 claims 1
- 239000011724 folic acid Substances 0.000 claims 1
- 235000011194 food seasoning agent Nutrition 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 239000011630 iodine Substances 0.000 claims 1
- 229910052740 iodine Inorganic materials 0.000 claims 1
- 229960004359 iodixanol Drugs 0.000 claims 1
- NBQNWMBBSKPBAY-UHFFFAOYSA-N iodixanol Chemical compound IC=1C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C(I)C=1N(C(=O)C)CC(O)CN(C(C)=O)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I NBQNWMBBSKPBAY-UHFFFAOYSA-N 0.000 claims 1
- 229960001025 iohexol Drugs 0.000 claims 1
- NTHXOOBQLCIOLC-UHFFFAOYSA-N iohexol Chemical compound OCC(O)CN(C(=O)C)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1I NTHXOOBQLCIOLC-UHFFFAOYSA-N 0.000 claims 1
- 229960004647 iopamidol Drugs 0.000 claims 1
- XQZXYNRDCRIARQ-LURJTMIESA-N iopamidol Chemical compound C[C@H](O)C(=O)NC1=C(I)C(C(=O)NC(CO)CO)=C(I)C(C(=O)NC(CO)CO)=C1I XQZXYNRDCRIARQ-LURJTMIESA-N 0.000 claims 1
- 229960002603 iopromide Drugs 0.000 claims 1
- DGAIEPBNLOQYER-UHFFFAOYSA-N iopromide Chemical compound COCC(=O)NC1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)N(C)CC(O)CO)=C1I DGAIEPBNLOQYER-UHFFFAOYSA-N 0.000 claims 1
- -1 ioxirane Chemical compound 0.000 claims 1
- 229940001447 lactate Drugs 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000004337 magnesium citrate Substances 0.000 claims 1
- 229960005336 magnesium citrate Drugs 0.000 claims 1
- 235000002538 magnesium citrate Nutrition 0.000 claims 1
- GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 claims 1
- 239000004137 magnesium phosphate Substances 0.000 claims 1
- 229960002261 magnesium phosphate Drugs 0.000 claims 1
- 229910000157 magnesium phosphate Inorganic materials 0.000 claims 1
- 235000010994 magnesium phosphates Nutrition 0.000 claims 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims 1
- 229960003390 magnesium sulfate Drugs 0.000 claims 1
- 235000019341 magnesium sulphate Nutrition 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229960004712 metrizoic acid Drugs 0.000 claims 1
- 235000015097 nutrients Nutrition 0.000 claims 1
- AVTYONGGKAJVTE-OLXYHTOASA-L potassium L-tartrate Chemical compound [K+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O AVTYONGGKAJVTE-OLXYHTOASA-L 0.000 claims 1
- 239000001103 potassium chloride Substances 0.000 claims 1
- 235000011164 potassium chloride Nutrition 0.000 claims 1
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 claims 1
- 229910052939 potassium sulfate Inorganic materials 0.000 claims 1
- 235000011151 potassium sulphates Nutrition 0.000 claims 1
- 239000001472 potassium tartrate Substances 0.000 claims 1
- 229940111695 potassium tartrate Drugs 0.000 claims 1
- 235000011005 potassium tartrates Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 235000002639 sodium chloride Nutrition 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 235000011083 sodium citrates Nutrition 0.000 claims 1
- 239000000176 sodium gluconate Substances 0.000 claims 1
- 235000012207 sodium gluconate Nutrition 0.000 claims 1
- 229940005574 sodium gluconate Drugs 0.000 claims 1
- GOZDTZWAMGHLDY-UHFFFAOYSA-L sodium picosulfate Chemical compound [Na+].[Na+].C1=CC(OS(=O)(=O)[O-])=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OS([O-])(=O)=O)C=C1 GOZDTZWAMGHLDY-UHFFFAOYSA-L 0.000 claims 1
- 229960005077 sodium picosulfate Drugs 0.000 claims 1
- 229960003010 sodium sulfate Drugs 0.000 claims 1
- WTWSHHITWMVLBX-DKWTVANSSA-M sodium;(2s)-2-aminobutanedioate;hydron Chemical compound [Na+].[O-]C(=O)[C@@H](N)CC(O)=O WTWSHHITWMVLBX-DKWTVANSSA-M 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 229960003495 thiamine Drugs 0.000 claims 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims 1
- 239000011573 trace mineral Substances 0.000 claims 1
- 235000013619 trace mineral Nutrition 0.000 claims 1
- PLSARIKBYIPYPF-UHFFFAOYSA-H trimagnesium dicitrate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O PLSARIKBYIPYPF-UHFFFAOYSA-H 0.000 claims 1
- 235000019155 vitamin A Nutrition 0.000 claims 1
- 239000011719 vitamin A Substances 0.000 claims 1
- 235000019156 vitamin B Nutrition 0.000 claims 1
- 239000011720 vitamin B Substances 0.000 claims 1
- 235000010374 vitamin B1 Nutrition 0.000 claims 1
- 239000011691 vitamin B1 Substances 0.000 claims 1
- 235000019154 vitamin C Nutrition 0.000 claims 1
- 239000011718 vitamin C Substances 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
- 229940045997 vitamin a Drugs 0.000 claims 1
- 229940046001 vitamin b complex Drugs 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
- 229910052725 zinc Inorganic materials 0.000 claims 1
- 235000016804 zinc Nutrition 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161552431P | 2011-10-27 | 2011-10-27 | |
| US61/552,431 | 2011-10-27 | ||
| US201261717599P | 2012-10-23 | 2012-10-23 | |
| US61/717,599 | 2012-10-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014537428A Division JP6240610B2 (ja) | 2011-10-27 | 2012-10-27 | 電解質下剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018008997A JP2018008997A (ja) | 2018-01-18 |
| JP2018008997A5 true JP2018008997A5 (enExample) | 2019-01-10 |
Family
ID=48166953
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014537428A Expired - Fee Related JP6240610B2 (ja) | 2011-10-27 | 2012-10-27 | 電解質下剤 |
| JP2017153176A Pending JP2018008997A (ja) | 2011-10-27 | 2017-08-08 | 電解質下剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014537428A Expired - Fee Related JP6240610B2 (ja) | 2011-10-27 | 2012-10-27 | 電解質下剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20150056140A1 (enExample) |
| EP (1) | EP2782581A4 (enExample) |
| JP (2) | JP6240610B2 (enExample) |
| KR (1) | KR20140090217A (enExample) |
| CN (1) | CN104010642B (enExample) |
| AU (2) | AU2012327212B2 (enExample) |
| BR (1) | BR112014009946A2 (enExample) |
| CA (1) | CA2853520C (enExample) |
| IL (1) | IL232218B (enExample) |
| IN (1) | IN2014DN03373A (enExample) |
| MX (1) | MX352891B (enExample) |
| PH (1) | PH12014500927B1 (enExample) |
| RU (1) | RU2640920C2 (enExample) |
| WO (1) | WO2013059881A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011342368B2 (en) | 2010-12-13 | 2016-11-17 | Rite-Prep Pty Ltd | Gastric and colonic formulations and methods for making and using them |
| TWI535461B (zh) | 2011-03-11 | 2016-06-01 | 諾金私人有限公司 | 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法 |
| US10166219B2 (en) | 2012-07-27 | 2019-01-01 | Redhill Bipharma Ltd. | Formulations and methods of manufacturing formulations for use in colonic evacuation |
| NZ743984A (en) | 2012-09-11 | 2019-10-25 | Norgine Bv | Compositions comprising polyethylene glycol, alkali metal or alkaline earth metal sulphates and electrolytes for use as colon cleansing compositions |
| JP6441890B2 (ja) | 2013-03-15 | 2018-12-19 | ブレインツリー・ラボラトリーズ，インコーポレイテッド | 硫酸塩の両用経口薬学的組成物錠剤およびその使用の方法 |
| CN103585173B (zh) * | 2013-10-28 | 2016-06-29 | 王显著 | 含硫酸钠和匹可硫酸的药物组合物 |
| WO2016040733A1 (en) * | 2014-09-12 | 2016-03-17 | Braintree Laboratories, Inc. | Sulfate salt solution laxative compositions and methods of use thereof |
| FR3049464B1 (fr) * | 2016-03-29 | 2021-08-06 | Marc Girard | Preparations coliques |
| US10143656B1 (en) | 2017-08-04 | 2018-12-04 | Braintree Laboratories, Inc. | Solid oral sulfate salt formulations for cleaning a colon and methods of using same |
| KR102127003B1 (ko) * | 2017-10-12 | 2020-06-25 | 주식회사 한국팜비오 | 황산염을 포함하는 대장 하제 조성물 |
| CN108244627A (zh) * | 2018-01-16 | 2018-07-06 | 广西天昌投资有限公司 | 一种具有润肠功能的香蕉口服液及其制备方法 |
| KR102111094B1 (ko) * | 2018-06-18 | 2020-05-14 | 주식회사 한국팜비오 | 무수황산나트륨, 황산칼륨, 무수황산마그네슘 및 시메티콘을 포함하는 장관하제 경구투여용 고형제제 조성물 |
| EP3813555A4 (en) * | 2018-06-29 | 2022-03-30 | Tets, Viktor, Veniaminovich | COMPOSITIONS FOR MODULATION OF INTESTINAL FLORA |
| RU2699222C1 (ru) * | 2019-04-29 | 2019-09-04 | Алексей Владимирович Воронов | Солевой электролитный раствор для проведения энтеральных инфузий |
| RU2709495C1 (ru) * | 2019-08-01 | 2019-12-18 | Общество с ограниченной ответственностью "Гелеспон" | Способ очищения кишечника и набор для его осуществления |
| KR20220122613A (ko) * | 2019-12-23 | 2022-09-02 | 주식회사 비보존 | 대장 하제 조성물 |
| KR20220033810A (ko) * | 2020-09-10 | 2022-03-17 | 강윤식 | 장 정결용 보조 음료 |
| US12239659B2 (en) | 2023-06-15 | 2025-03-04 | Braintree Laboratories, Inc. | Methods of administering safe colon cleansing compositions |
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| US6162464A (en) * | 1997-03-31 | 2000-12-19 | Inkine Pharmaceutical, Inc. | Non-aqueous colonic purgative formulations |
| JP2000060487A (ja) * | 1998-08-27 | 2000-02-29 | Kao Corp | 便秘改善剤 |
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| JP2008115085A (ja) * | 2006-11-01 | 2008-05-22 | Tendou Seiyaku Kk | 緩下剤 |
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| US20090258090A1 (en) * | 2008-04-11 | 2009-10-15 | Braintree Laboratories, Inc. | Colon cleansing solution |
| WO2011047178A1 (en) * | 2009-10-14 | 2011-04-21 | Gi Innovation, Pllc | Colon cleansing of residual stool and secretions during colonoscopy |
| JP2011135936A (ja) * | 2009-12-25 | 2011-07-14 | Toshiba Corp | 画像処理装置、医用画像診断装置および画像処理プログラム |
| AU2011342368B2 (en) * | 2010-12-13 | 2016-11-17 | Rite-Prep Pty Ltd | Gastric and colonic formulations and methods for making and using them |
| WO2012102799A2 (en) * | 2011-01-28 | 2012-08-02 | Shaver William A | Method, composition and package for bowel cleansing |
-
2012
- 2012-10-27 IN IN3373DEN2014 patent/IN2014DN03373A/en unknown
- 2012-10-27 WO PCT/AU2012/001315 patent/WO2013059881A1/en not_active Ceased
- 2012-10-27 EP EP12844538.4A patent/EP2782581A4/en not_active Withdrawn
- 2012-10-27 CA CA2853520A patent/CA2853520C/en active Active
- 2012-10-27 US US14/353,744 patent/US20150056140A1/en not_active Abandoned
- 2012-10-27 CN CN201280058877.5A patent/CN104010642B/zh not_active Expired - Fee Related
- 2012-10-27 MX MX2014004962A patent/MX352891B/es active IP Right Grant
- 2012-10-27 BR BR112014009946A patent/BR112014009946A2/pt active Search and Examination
- 2012-10-27 PH PH1/2014/500927A patent/PH12014500927B1/en unknown
- 2012-10-27 RU RU2014121255A patent/RU2640920C2/ru not_active IP Right Cessation
- 2012-10-27 JP JP2014537428A patent/JP6240610B2/ja not_active Expired - Fee Related
- 2012-10-27 KR KR1020147013786A patent/KR20140090217A/ko not_active Ceased
- 2012-10-27 AU AU2012327212A patent/AU2012327212B2/en active Active
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2014
- 2014-04-24 IL IL232218A patent/IL232218B/en active IP Right Grant
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2016
- 2016-08-12 AU AU2016213892A patent/AU2016213892B2/en active Active
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2017
- 2017-08-08 JP JP2017153176A patent/JP2018008997A/ja active Pending
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