CN104010642B - 电解质泻药 - Google Patents

电解质泻药 Download PDF

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Publication number
CN104010642B
CN104010642B CN201280058877.5A CN201280058877A CN104010642B CN 104010642 B CN104010642 B CN 104010642B CN 201280058877 A CN201280058877 A CN 201280058877A CN 104010642 B CN104010642 B CN 104010642B
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CN
China
Prior art keywords
composition
sodium
salt
water
soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280058877.5A
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English (en)
Chinese (zh)
Other versions
CN104010642A (zh
Inventor
托马斯·朱利叶斯·波洛迪
桑佳伊·莱姆拉克哈
约翰·撒克逊
安东尼·外特斯坦
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Salix Pharmaceuticals Ltd
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Salix Pharmaceuticals Ltd
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Filing date
Publication date
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Publication of CN104010642A publication Critical patent/CN104010642A/zh
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Publication of CN104010642B publication Critical patent/CN104010642B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201280058877.5A 2011-10-27 2012-10-27 电解质泻药 Expired - Fee Related CN104010642B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161552431P 2011-10-27 2011-10-27
US61/552,431 2011-10-27
US201261717599P 2012-10-23 2012-10-23
US61/717,599 2012-10-23
PCT/AU2012/001315 WO2013059881A1 (en) 2011-10-27 2012-10-27 Electrolyte purgatives

Publications (2)

Publication Number Publication Date
CN104010642A CN104010642A (zh) 2014-08-27
CN104010642B true CN104010642B (zh) 2018-08-17

Family

ID=48166953

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280058877.5A Expired - Fee Related CN104010642B (zh) 2011-10-27 2012-10-27 电解质泻药

Country Status (14)

Country Link
US (1) US20150056140A1 (enExample)
EP (1) EP2782581A4 (enExample)
JP (2) JP6240610B2 (enExample)
KR (1) KR20140090217A (enExample)
CN (1) CN104010642B (enExample)
AU (2) AU2012327212B2 (enExample)
BR (1) BR112014009946A2 (enExample)
CA (1) CA2853520C (enExample)
IL (1) IL232218B (enExample)
IN (1) IN2014DN03373A (enExample)
MX (1) MX352891B (enExample)
PH (1) PH12014500927B1 (enExample)
RU (1) RU2640920C2 (enExample)
WO (1) WO2013059881A1 (enExample)

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CA2821196C (en) 2010-12-13 2022-11-22 Thomas Julius Borody Gastric and colonic formulations and methods for making and using them
TWI535461B (zh) 2011-03-11 2016-06-01 諾金私人有限公司 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法
PT2877163T (pt) 2012-07-27 2019-05-24 Redhill Biopharma Ltd Formulações e métodos de fabrico de formulações para utilização na evacuação colónica
KR20170098980A (ko) 2012-09-11 2017-08-30 노어긴 비.브이. Peg 및 아스코르베이트를 포함하는 조성물
EP3563838A1 (en) 2013-03-15 2019-11-06 Braintree Laboratories, Inc. Dual use oral pharmaceutical composition tablets of suflate salts and methods of use thereof
CN103585173B (zh) * 2013-10-28 2016-06-29 王显著 含硫酸钠和匹可硫酸的药物组合物
EP3191105A4 (en) * 2014-09-12 2018-05-02 Braintree Laboratories, Inc. Sulfate salt solution laxative compositions and methods of use thereof
FR3049464B1 (fr) * 2016-03-29 2021-08-06 Marc Girard Preparations coliques
US10143656B1 (en) 2017-08-04 2018-12-04 Braintree Laboratories, Inc. Solid oral sulfate salt formulations for cleaning a colon and methods of using same
KR102127003B1 (ko) * 2017-10-12 2020-06-25 주식회사 한국팜비오 황산염을 포함하는 대장 하제 조성물
CN108244627A (zh) * 2018-01-16 2018-07-06 广西天昌投资有限公司 一种具有润肠功能的香蕉口服液及其制备方法
KR102111094B1 (ko) * 2018-06-18 2020-05-14 주식회사 한국팜비오 무수황산나트륨, 황산칼륨, 무수황산마그네슘 및 시메티콘을 포함하는 장관하제 경구투여용 고형제제 조성물
WO2020006389A1 (en) * 2018-06-29 2020-01-02 Viktor Veniaminovich Tets Compositions for modulating gut microbiota
RU2699222C1 (ru) * 2019-04-29 2019-09-04 Алексей Владимирович Воронов Солевой электролитный раствор для проведения энтеральных инфузий
RU2709495C1 (ru) * 2019-08-01 2019-12-18 Общество с ограниченной ответственностью "Гелеспон" Способ очищения кишечника и набор для его осуществления
WO2021133017A1 (ko) * 2019-12-23 2021-07-01 주식회사 비보존 대장 하제 조성물
KR20220033810A (ko) * 2020-09-10 2022-03-17 강윤식 장 정결용 보조 음료
WO2024256873A1 (en) 2023-06-15 2024-12-19 Sebela Ireland Limited Methods of administering safe colon cleansing compositions
KR20250176963A (ko) * 2024-06-13 2025-12-22 주식회사태준제약 장정결을 위한 고형제제

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2012079118A1 (en) * 2010-12-13 2012-06-21 Borody Thomas J Gastric and colonic formulations and methods for making and using them

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US6162464A (en) * 1997-03-31 2000-12-19 Inkine Pharmaceutical, Inc. Non-aqueous colonic purgative formulations
JP2000060487A (ja) * 1998-08-27 2000-02-29 Kao Corp 便秘改善剤
EE04580B1 (et) * 2001-06-29 2006-02-15 Tartu �likool Mikroorganismi tüvi Lactobacillus fermentum ME-3 kui antimikroobne ja antioksüdantne probiootikum
US7101573B2 (en) * 2001-09-28 2006-09-05 Mcneil-Pcc, Inc. Simethicone solid oral dosage form
AUPS088702A0 (en) * 2002-03-04 2002-03-28 Borody, Thomas Julius Electrolyte purgative
JP4458761B2 (ja) * 2003-03-27 2010-04-28 ロート製薬株式会社 瀉下用製剤
US7687075B2 (en) * 2003-11-19 2010-03-30 Salix Pharmaceuticals, Ltd. Colonic purgative composition with soluble binding agent
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US9125833B2 (en) * 2005-11-02 2015-09-08 Relmada Therapeutics, Inc. Multimodal abuse resistant and extended release opioid formulations
WO2007057924A1 (en) * 2005-11-21 2007-05-24 Panacea Biotec Ltd Laxative composition on the basis of triphala
WO2008021394A2 (en) * 2006-08-15 2008-02-21 Theraquest Biosciences, Llc Pharmaceutical formulations of cannabinoids and method of use
JP2008115085A (ja) * 2006-11-01 2008-05-22 Tendou Seiyaku Kk 緩下剤
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BR112013019360A2 (pt) * 2011-01-28 2017-03-28 A Shaver William ingredientes, componente seco de formulação oral de baixo teor de cloreto farmaceuticamente aceitável para limpeza de cólon, solução de base de reposição de eletrólito aquosa para uso em lavagem colônica, métodos para limpar os intestinos de paciente, para preparar solução aquosa para limpeza do cólon e para aumentar substancialmente o paladar de limpador de cólon e kits para evacuação do cólon.

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Also Published As

Publication number Publication date
EP2782581A4 (en) 2015-05-20
JP2018008997A (ja) 2018-01-18
NZ723576A (en) 2018-07-27
WO2013059881A1 (en) 2013-05-02
KR20140090217A (ko) 2014-07-16
BR112014009946A2 (pt) 2017-04-25
CA2853520A1 (en) 2013-05-02
AU2016213892A1 (en) 2016-09-01
IL232218B (en) 2018-10-31
IL232218A0 (en) 2014-06-30
AU2012327212A1 (en) 2013-05-23
EP2782581A1 (en) 2014-10-01
AU2012327212B2 (en) 2016-05-12
IN2014DN03373A (enExample) 2015-06-05
PH12014500927A1 (en) 2014-06-16
JP2015510491A (ja) 2015-04-09
MX352891B (es) 2017-12-13
CA2853520C (en) 2021-11-16
AU2016213892B2 (en) 2018-04-05
CN104010642A (zh) 2014-08-27
RU2640920C2 (ru) 2018-01-12
MX2014004962A (es) 2015-01-16
NZ624088A (en) 2016-09-30
PH12014500927B1 (en) 2017-09-06
US20150056140A1 (en) 2015-02-26
RU2014121255A (ru) 2015-12-10
JP6240610B2 (ja) 2017-11-29

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Granted publication date: 20180817

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CF01 Termination of patent right due to non-payment of annual fee