JP2017524140A5 - - Google Patents
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- JP2017524140A5 JP2017524140A5 JP2017507701A JP2017507701A JP2017524140A5 JP 2017524140 A5 JP2017524140 A5 JP 2017524140A5 JP 2017507701 A JP2017507701 A JP 2017507701A JP 2017507701 A JP2017507701 A JP 2017507701A JP 2017524140 A5 JP2017524140 A5 JP 2017524140A5
- Authority
- JP
- Japan
- Prior art keywords
- metal
- analyte
- gold
- target analyte
- nanostructures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229910052751 metal Inorganic materials 0.000 claims description 108
- 239000002184 metal Substances 0.000 claims description 108
- 239000012491 analyte Substances 0.000 claims description 72
- 239000002086 nanomaterial Substances 0.000 claims description 69
- 238000001514 detection method Methods 0.000 claims description 49
- 239000002131 composite material Substances 0.000 claims description 46
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 34
- 229910052737 gold Inorganic materials 0.000 claims description 34
- 239000010931 gold Substances 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 28
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 26
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 26
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 26
- 239000002052 molecular layer Substances 0.000 claims description 21
- 229910052709 silver Inorganic materials 0.000 claims description 21
- 239000004332 silver Substances 0.000 claims description 21
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 19
- 239000010949 copper Substances 0.000 claims description 19
- 229910052802 copper Inorganic materials 0.000 claims description 19
- 239000000427 antigen Substances 0.000 claims description 15
- 108091007433 antigens Proteins 0.000 claims description 15
- 102000036639 antigens Human genes 0.000 claims description 15
- 238000003556 assay Methods 0.000 claims description 14
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 13
- 229910052793 cadmium Inorganic materials 0.000 claims description 13
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 claims description 13
- 229910052763 palladium Inorganic materials 0.000 claims description 13
- 229910052697 platinum Inorganic materials 0.000 claims description 13
- 229910052725 zinc Inorganic materials 0.000 claims description 13
- 239000011701 zinc Substances 0.000 claims description 13
- 239000002105 nanoparticle Substances 0.000 claims description 12
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 10
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 10
- 239000011324 bead Substances 0.000 claims description 10
- 239000011248 coating agent Substances 0.000 claims description 10
- 238000000576 coating method Methods 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 8
- 229920000642 polymer Polymers 0.000 claims description 7
- 239000000956 alloy Substances 0.000 claims description 5
- 229910045601 alloy Inorganic materials 0.000 claims description 5
- 229910052742 iron Inorganic materials 0.000 claims description 5
- 229910052759 nickel Inorganic materials 0.000 claims description 5
- 239000003550 marker Substances 0.000 claims description 4
- 150000002739 metals Chemical class 0.000 claims description 4
- 108091023037 Aptamer Proteins 0.000 claims description 3
- 102000011931 Nucleoproteins Human genes 0.000 claims description 3
- 108010061100 Nucleoproteins Proteins 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 239000003446 ligand Substances 0.000 claims description 3
- 239000002073 nanorod Substances 0.000 claims description 3
- 239000002078 nanoshell Substances 0.000 claims description 3
- 239000002071 nanotube Substances 0.000 claims description 3
- 239000002070 nanowire Substances 0.000 claims description 3
- 108091033319 polynucleotide Proteins 0.000 claims description 3
- 102000040430 polynucleotide Human genes 0.000 claims description 3
- 239000002157 polynucleotide Substances 0.000 claims description 3
- 229920001184 polypeptide Polymers 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 3
- 241000606646 Anaplasma Species 0.000 claims description 2
- 241000589968 Borrelia Species 0.000 claims description 2
- 101800000407 Brain natriuretic peptide 32 Proteins 0.000 claims description 2
- 102400000667 Brain natriuretic peptide 32 Human genes 0.000 claims description 2
- 101800002247 Brain natriuretic peptide 45 Proteins 0.000 claims description 2
- 108010074051 C-Reactive Protein Proteins 0.000 claims description 2
- 102100032752 C-reactive protein Human genes 0.000 claims description 2
- 241000701931 Canine parvovirus Species 0.000 claims description 2
- 241000282465 Canis Species 0.000 claims description 2
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical group IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 claims description 2
- 241000714165 Feline leukemia virus Species 0.000 claims description 2
- 208000016604 Lyme disease Diseases 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 229920002873 Polyethylenimine Polymers 0.000 claims description 2
- 102000011923 Thyrotropin Human genes 0.000 claims description 2
- 108010061174 Thyrotropin Proteins 0.000 claims description 2
- 238000002835 absorbance Methods 0.000 claims description 2
- 238000000862 absorption spectrum Methods 0.000 claims description 2
- 201000011510 cancer Diseases 0.000 claims description 2
- 238000000295 emission spectrum Methods 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 claims description 2
- 238000002329 infrared spectrum Methods 0.000 claims description 2
- 239000002055 nanoplate Substances 0.000 claims description 2
- HPNRHPKXQZSDFX-OAQDCNSJSA-N nesiritide Chemical compound C([C@H]1C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1N=CNC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 HPNRHPKXQZSDFX-OAQDCNSJSA-N 0.000 claims description 2
- 230000003287 optical effect Effects 0.000 claims description 2
- 230000001575 pathological effect Effects 0.000 claims description 2
- 239000008188 pellet Substances 0.000 claims description 2
- 230000004962 physiological condition Effects 0.000 claims description 2
- 229920000058 polyacrylate Polymers 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 230000003595 spectral effect Effects 0.000 claims description 2
- 229940034208 thyroxine Drugs 0.000 claims description 2
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 claims description 2
- 241000605314 Ehrlichia Species 0.000 claims 1
- 241000224467 Giardia intestinalis Species 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 229940085435 giardia lamblia Drugs 0.000 claims 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000224466 Giardia Species 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021149078A JP7240460B2 (ja) | 2014-08-13 | 2021-09-14 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462037071P | 2014-08-13 | 2014-08-13 | |
| US62/037,071 | 2014-08-13 | ||
| US201462082468P | 2014-11-20 | 2014-11-20 | |
| US62/082,468 | 2014-11-20 | ||
| PCT/US2015/045041 WO2016025703A2 (en) | 2014-08-13 | 2015-08-13 | Signal amplification in plasmonic specific-binding partner assays |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021149078A Division JP7240460B2 (ja) | 2014-08-13 | 2021-09-14 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524140A JP2017524140A (ja) | 2017-08-24 |
| JP2017524140A5 true JP2017524140A5 (cg-RX-API-DMAC7.html) | 2018-09-20 |
| JP6945445B2 JP6945445B2 (ja) | 2021-10-06 |
Family
ID=55302002
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017507701A Active JP6945445B2 (ja) | 2014-08-13 | 2015-08-13 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2021149078A Active JP7240460B2 (ja) | 2014-08-13 | 2021-09-14 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2023032372A Pending JP2023067953A (ja) | 2014-08-13 | 2023-03-03 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021149078A Active JP7240460B2 (ja) | 2014-08-13 | 2021-09-14 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
| JP2023032372A Pending JP2023067953A (ja) | 2014-08-13 | 2023-03-03 | プラズモン特異的結合パートナーアッセイにおけるシグナル増幅 |
Country Status (18)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102065387B1 (ko) | 2011-11-21 | 2020-01-13 | 아박시스, 인크. | 측방 유동 및 관련된 면역검정에서의 신호 증폭 |
| TWI691716B (zh) | 2014-08-13 | 2020-04-21 | 美商艾巴希斯公司 | 電漿特異性結合搭配物檢定中之信號放大 |
| WO2016187588A1 (en) * | 2015-05-21 | 2016-11-24 | Lamdagen Corporation | Plasmonic nanoparticles and lspr-based assays |
| HUE067974T2 (hu) | 2015-08-04 | 2024-11-28 | Zoetis Services Llc | Jelamplifikáció oldatalapú plazmonspecifikus kötõpartner-vizsgálatokban |
| JP2017150865A (ja) * | 2016-02-23 | 2017-08-31 | コニカミノルタ株式会社 | ガス検知方法及びガス検知装置 |
| KR101842763B1 (ko) * | 2016-03-11 | 2018-05-14 | 경희대학교 산학협력단 | 구리 나노구조물의 제조방법 |
| MX2019008970A (es) | 2017-01-30 | 2019-12-19 | Abay Sa | Ensayos de socio de unión específico de plasmón basados en solución y nanoestructuras metálicas. |
| JP6926731B2 (ja) * | 2017-06-30 | 2021-08-25 | コニカミノルタ株式会社 | 検出チップ、検出キット、検出システムおよび被検出物質の検出方法 |
| JP2021520484A (ja) * | 2018-04-03 | 2021-08-19 | サノフイＳａｎｏｆｉ | ラテラルフロー免疫アッセイストリップ装置 |
| CN111024942B (zh) * | 2019-11-27 | 2023-06-02 | 北京农业智能装备技术研究中心 | 一种免疫层析试纸条的高灵敏检测方法 |
| CA3215851A1 (en) * | 2021-04-21 | 2022-10-27 | Udayan Kanade | System and method for simulating a localized surface plasmon resonance (lspr) spectrometer |
| WO2024196805A1 (en) | 2023-03-17 | 2024-09-26 | Beckman Coulter, Inc. | Benzothienopyrrole cyanine dyes |
| WO2025014842A1 (en) * | 2023-07-07 | 2025-01-16 | Ohio University | Test strips and methods of testing for bio-analytes using titanium nitride nanoparticles and gold coated copper nanoparticles |
| EP4567426A1 (en) * | 2023-12-05 | 2025-06-11 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | A nanoparticle, a suspension comprising nanoparticles, and related method |
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