JP2017519519A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017519519A5 JP2017519519A5 JP2017510762A JP2017510762A JP2017519519A5 JP 2017519519 A5 JP2017519519 A5 JP 2017519519A5 JP 2017510762 A JP2017510762 A JP 2017510762A JP 2017510762 A JP2017510762 A JP 2017510762A JP 2017519519 A5 JP2017519519 A5 JP 2017519519A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nicotine demethylase
- mutations
- tobacco plant
- demethylase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14167598.3 | 2014-05-08 | ||
| EP14167598 | 2014-05-08 | ||
| EP14001645 | 2014-05-09 | ||
| EP14001645.2 | 2014-05-09 | ||
| PCT/EP2015/060124 WO2015169927A1 (en) | 2014-05-08 | 2015-05-07 | Reduction of nicotine to nornicotine conversion in plants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017519519A JP2017519519A (ja) | 2017-07-20 |
| JP2017519519A5 true JP2017519519A5 (enExample) | 2018-06-14 |
| JP6871158B2 JP6871158B2 (ja) | 2021-05-12 |
Family
ID=53276066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017510762A Expired - Fee Related JP6871158B2 (ja) | 2014-05-08 | 2015-05-07 | 植物体におけるニコチンからノルニコチンへの変換の低減 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10415050B2 (enExample) |
| EP (1) | EP3140404A1 (enExample) |
| JP (1) | JP6871158B2 (enExample) |
| KR (1) | KR102442802B1 (enExample) |
| CN (1) | CN106459923B (enExample) |
| BR (1) | BR112016025234A2 (enExample) |
| CA (1) | CA2944965A1 (enExample) |
| MX (1) | MX2016014635A (enExample) |
| PH (1) | PH12016501718A1 (enExample) |
| RU (1) | RU2733837C2 (enExample) |
| WO (1) | WO2015169927A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106636146B (zh) * | 2017-02-16 | 2019-09-13 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e5基因突变体及其应用 |
| US11046969B2 (en) * | 2017-05-24 | 2021-06-29 | Epiplanta Biotech Ltd. | Transgenic plant and the method for producing the same |
| WO2018222667A1 (en) * | 2017-05-31 | 2018-12-06 | 22Nd Century Limited, Llc | Genome editing methods for producing low-nicotine tobacco products |
| WO2019113360A1 (en) | 2017-12-07 | 2019-06-13 | University Of Kentucky Research Foundation | bZIP TRANSCRIPTION FACTORS REGULATE CONVERSION OF NICOTINE TO NORNICOTINE |
| CN108192900B (zh) * | 2018-01-16 | 2021-11-30 | 西南大学 | 烟草烟碱去甲基化酶基因cyp82e4的编辑失活载体及其应用 |
| KR102995073B1 (ko) | 2018-03-28 | 2026-07-24 | 필립모리스 프로덕츠 에스.에이. | 식물 내 아미노산 함량 조절 |
| WO2019185699A1 (en) | 2018-03-28 | 2019-10-03 | Philip Morris Products S.A. | Modulating reducing sugar content in a plant |
| CN108424921B (zh) * | 2018-04-20 | 2021-04-20 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e10基因错义突变体m594及其应用 |
| BR112021001364A2 (pt) | 2018-07-26 | 2021-04-20 | Altria Client Services Llc | composições e métodos à base de engenharia de pmt para produzir plantas de tabaco e produtos tendo níveis de alcaloides alterados |
| GB201812603D0 (en) | 2018-08-02 | 2018-09-19 | British American Tobacco Investments Ltd | Method |
| WO2020027970A1 (en) * | 2018-08-02 | 2020-02-06 | Antidote Therapeutics, Inc. | Novel nicotine degrading enzyme variants |
| EP3902390A1 (en) * | 2018-12-30 | 2021-11-03 | Philip Morris Products S.A. | Modulation of nitrate levels in plants via mutation of nitrate reductase |
| KR20220070305A (ko) | 2019-10-01 | 2022-05-30 | 필립모리스 프로덕츠 에스.에이. | 식물 내 환원당 (inv) 함량 조절 |
| WO2021063863A1 (en) | 2019-10-01 | 2021-04-08 | Philip Morris Products S.A. | Modulating sugar and amino acid content in a plant (sultr3) |
| WO2021113337A1 (en) * | 2019-12-03 | 2021-06-10 | Altria Client Services Llc | Compositions and methods for producing tobacco plants and products having altered alkaloid levels |
| WO2021221752A2 (en) | 2020-02-06 | 2021-11-04 | Trustees Of Boston University | High throughput assay for identifying microbial redox enzymes |
| WO2021158973A1 (en) | 2020-02-06 | 2021-08-12 | Trustees Of Boston University | Enzyme-based electrochemical nicotine biosensor |
| BR112022021066A2 (pt) * | 2020-04-17 | 2022-12-06 | Japan Tobacco Inc | Corpo de planta do gênero nicotiana com baixo teor de alcaloide e método de produção do mesmo |
| CN111505158B (zh) * | 2020-05-09 | 2022-09-23 | 云南省烟草农业科学研究院 | 一种基于孵化处理的尼古丁转化烟株色质快速筛查方法 |
| US20240368615A1 (en) | 2021-09-10 | 2024-11-07 | Philip Morris Products S.A. | Modulating alkaloid profiles in nicotiana tabacum |
| CN113980978B (zh) * | 2021-11-22 | 2023-12-26 | 云南中烟工业有限责任公司 | 一种烟草烟碱转运蛋白相关的基因及其应用 |
| WO2023117661A1 (en) | 2021-12-20 | 2023-06-29 | Philip Morris Products S.A. | Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase |
| US20250084427A1 (en) | 2021-12-21 | 2025-03-13 | Philip Morris Products S.A. | Modulation of nicotine production by alteration of nicotinamidase expression or function in plants |
| CN114540382B (zh) * | 2022-02-18 | 2023-07-18 | 贵州省烟草科学研究院 | 烟草镉转运基因NtPLA1及应用 |
| KR20250078994A (ko) | 2022-10-13 | 2025-06-04 | 필립모리스 프로덕츠 에스.에이. | Ntp2 조절에 의한 잎 바이오매스 및 질소 사용 효율 증가 |
| WO2024160860A1 (en) | 2023-02-02 | 2024-08-08 | Philip Morris Products S.A. | Modulation of genes coding for lysine ketoglutarate reductase |
| KR20250139371A (ko) | 2023-02-02 | 2025-09-23 | 필립모리스 프로덕츠 에스.에이. | 당 수송체의 조절 |
| WO2025003105A1 (en) | 2023-06-29 | 2025-01-02 | Philip Morris Products S.A. | Modulation of genes coding for glutamate dehydrogenase |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5810020A (en) | 1993-09-07 | 1998-09-22 | Osmotek, Inc. | Process for removing nitrogen-containing anions and tobacco-specific nitrosamines from tobacco products |
| US6202649B1 (en) | 1996-12-02 | 2001-03-20 | Regent Court Technologies | Method of treating tobacco to reduce nitrosamine content, and products produced thereby |
| EE9900590A (et) | 1997-06-20 | 2000-08-15 | Regent Court Technologies | Nitrosamiinide sisaldust vähendav tubaka töötlemise meetod ja seejuures saadavad tooted |
| US7700851B2 (en) * | 2001-11-13 | 2010-04-20 | U.S. Smokeless Tobacco Company | Tobacco nicotine demethylase genomic clone and uses thereof |
| ATE530656T1 (de) | 2005-02-23 | 2011-11-15 | Univ North Carolina State | Veränderung des alkaloidgehaltes in tabak durch modifikation spezifischer cytochrome p450 gene. |
| US7884263B2 (en) * | 2005-02-23 | 2011-02-08 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes |
| AU2007329776B2 (en) | 2006-10-13 | 2013-05-16 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes |
| RU2324737C1 (ru) * | 2006-10-18 | 2008-05-20 | Институт цитологии и генетики Сибирского отделения Российской академии наук (СО РАН) | Способ получения трансгенных растений табака с повышенным содержанием пролина |
| US8319011B2 (en) * | 2006-12-15 | 2012-11-27 | U.S. Smokeless Tobacco Company Llc | Tobacco plants having reduced nicotine demethylase activity |
| CN101939431B (zh) | 2007-11-12 | 2015-01-28 | 北卡罗来纳州立大学 | 通过修饰特定细胞色素p450基因改变烟草生物碱含量 |
| AP3226A (en) | 2007-12-13 | 2015-04-30 | Philip Morris Products Sa | Transgenic plants modifier for reducede cadmium transport, derivative products, and related methods |
| US7883371B1 (en) | 2009-07-22 | 2011-02-08 | Hon Hai Precision Ind. Co., Ltd. | Electrical connector with improved contact footprints |
| MX337123B (es) * | 2010-01-15 | 2016-02-12 | Univ North Carolina State | Composiciones y metodos para minimizar la sintesis de nornicotina en el tabaco. |
| ES2698154T3 (es) | 2010-09-03 | 2019-01-31 | Philip Morris Products Sa | Reducción de metales pesados en plantas |
-
2015
- 2015-05-07 CA CA2944965A patent/CA2944965A1/en not_active Abandoned
- 2015-05-07 KR KR1020167031693A patent/KR102442802B1/ko not_active Expired - Fee Related
- 2015-05-07 JP JP2017510762A patent/JP6871158B2/ja not_active Expired - Fee Related
- 2015-05-07 WO PCT/EP2015/060124 patent/WO2015169927A1/en not_active Ceased
- 2015-05-07 BR BR112016025234A patent/BR112016025234A2/pt not_active Application Discontinuation
- 2015-05-07 MX MX2016014635A patent/MX2016014635A/es unknown
- 2015-05-07 US US15/306,172 patent/US10415050B2/en active Active
- 2015-05-07 RU RU2016144409A patent/RU2733837C2/ru active
- 2015-05-07 CN CN201580023352.1A patent/CN106459923B/zh not_active Expired - Fee Related
- 2015-05-07 EP EP15726007.6A patent/EP3140404A1/en not_active Withdrawn
-
2016
- 2016-09-01 PH PH12016501718A patent/PH12016501718A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2016144409A (ru) | Снижение превращения никотина в норникотин в растениях | |
| JP7470139B2 (ja) | 方法 | |
| RU2017105148A (ru) | Гены протеаз табака | |
| JP2016508032A5 (enExample) | ||
| US10851384B2 (en) | Tobacco having altered leaf properties and methods of making and using | |
| JP6693747B2 (ja) | 植物体中のたばこ特異的ニトロソアミンの低減 | |
| CN113271768B (zh) | 经由硝酸盐还原酶的突变来调节植物中的硝酸盐水平 | |
| JP2017529850A5 (enExample) | ||
| RU2018112407A (ru) | Растения со сниженным содержанием аспарагина | |
| CN105960460A (zh) | 在叶中具有改变量的一种或多种生物碱的烟草植物及使用此类植物的方法 | |
| JP2022515435A5 (enExample) | ||
| EP3993611A1 (en) | Method for modulating the alkaloid content of a tobacco plant | |
| CN112840030B (zh) | 使用组成性高亲和力阳离子外排蛋白减少烟草中亚硝胺含量的方法 | |
| CN116096902A (zh) | 用于调节烟草中尼古丁水平的方法 | |
| JP7696368B2 (ja) | タバコ植物及びたばこ製品 | |
| JP6699832B2 (ja) | ステイグリーンキュウリ植物 | |
| EP4458140A1 (en) | Tobacco plant | |
| RU2815762C2 (ru) | Модулирование уровней нитратов в растениях посредством мутации нитратредуктазы | |
| JP2019503180A (ja) | 植物における側芽の発芽の改変方法及び該方法によって得られる植物 | |
| CN121335615A (zh) | 编码谷氨酸脱氢酶的基因的调节 | |
| CN120530195A (zh) | 糖转运蛋白的调节 | |
| CN115516098A (zh) | 与改进的氮利用效率有关的方法和组合物 | |
| JP2022538481A (ja) | タバコ植物のアルカロイド含有量を調節する方法 | |
| US20190017059A1 (en) | Method for modifying lateral budding | |
| JP2019503178A (ja) | 植物における側芽の発芽の改変方法及び該方法によって得られる植物 |