BR112022021066A2 - Corpo de planta do gênero nicotiana com baixo teor de alcaloide e método de produção do mesmo - Google Patents
Corpo de planta do gênero nicotiana com baixo teor de alcaloide e método de produção do mesmoInfo
- Publication number
- BR112022021066A2 BR112022021066A2 BR112022021066A BR112022021066A BR112022021066A2 BR 112022021066 A2 BR112022021066 A2 BR 112022021066A2 BR 112022021066 A BR112022021066 A BR 112022021066A BR 112022021066 A BR112022021066 A BR 112022021066A BR 112022021066 A2 BR112022021066 A2 BR 112022021066A2
- Authority
- BR
- Brazil
- Prior art keywords
- plant
- alkaloid content
- production method
- low alkaloid
- genus nicotiana
- Prior art date
Links
- 241000208125 Nicotiana Species 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 244000061176 Nicotiana tabacum Species 0.000 abstract 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 abstract 2
- 241000196324 Embryophyta Species 0.000 abstract 1
- 102000004316 Oxidoreductases Human genes 0.000 abstract 1
- 108090000854 Oxidoreductases Proteins 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- 229940009098 aspartate Drugs 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
- A01H1/10—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits
- A01H1/101—Processes for modifying non-agronomic quality output traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine or caffeine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/82—Solanaceae, e.g. pepper, tobacco, potato, tomato or eggplant
- A01H6/823—Nicotiana, e.g. tobacco
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
- A01H5/12—Leaves
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12Y104/03016—L-Aspartate oxidase (1.4.3.16)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Botany (AREA)
- Biochemistry (AREA)
- Physiology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Nutrition Science (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
CORPO DE PLANTA DO GÊNERO NICOTIANA COM BAIXO TEOR DE ALCALOIDE E MÉTODO DE PRODUÇÃO DO MESMO. Uma modalidade da presente invenção fornece uma planta de tabaco tendo um baixo teor de alcaloide. Na planta de tabaco, uma função de um gene que codifica a aspartato oxidase AO2 é suprimida.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2020074233 | 2020-04-17 | ||
PCT/JP2021/015920 WO2021210688A1 (ja) | 2020-04-17 | 2021-04-19 | 低アルカロイド含量のタバコ属植物体およびその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022021066A2 true BR112022021066A2 (pt) | 2022-12-06 |
Family
ID=78085131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022021066A BR112022021066A2 (pt) | 2020-04-17 | 2021-04-19 | Corpo de planta do gênero nicotiana com baixo teor de alcaloide e método de produção do mesmo |
Country Status (6)
Country | Link |
---|---|
US (1) | US20230120622A1 (pt) |
EP (1) | EP4136964A4 (pt) |
JP (1) | JP7210806B2 (pt) |
CN (1) | CN115485386B (pt) |
BR (1) | BR112022021066A2 (pt) |
WO (1) | WO2021210688A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115426874A (zh) * | 2020-04-21 | 2022-12-02 | 日本烟草产业株式会社 | 烟草植物体及其制备方法 |
CN113528537A (zh) * | 2021-08-11 | 2021-10-22 | 云南省烟草农业科学研究院 | 一种降低烟叶烟碱含量的NtQPT2基因突变体及其应用 |
WO2023127723A1 (ja) * | 2021-12-27 | 2023-07-06 | 日本たばこ産業株式会社 | タバコ植物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101672423B1 (ko) | 2005-02-28 | 2016-11-03 | 22엔디 센츄리 리미티드, 엘엘씨 | 식물의 니코틴 알칼로이드 수준의 감소 |
WO2011102394A1 (ja) | 2010-02-17 | 2011-08-25 | 日本たばこ産業株式会社 | 植物内容成分の調節因子、およびその利用 |
EP3140404A1 (en) * | 2014-05-08 | 2017-03-15 | Philip Morris Products S.A. | Reduction of nicotine to nornicotine conversion in plants |
AU2016362578B2 (en) * | 2015-12-04 | 2022-08-04 | North Carolina State University | Targeted mutagenesis of tobacco berberine bridge enzyme-like nucleic acids |
CN116058286A (zh) * | 2016-03-30 | 2023-05-05 | 日本烟草产业株式会社 | 烟草植物体及其制备方法 |
US20180340180A1 (en) * | 2017-05-19 | 2018-11-29 | 22Nd Century Limited, Llc | Dominant-negative genetic manipulation to make low-nicotine tobacco products |
US20200140875A1 (en) * | 2017-05-31 | 2020-05-07 | 22Nd Century Limited, Llc | Genome editing methods for producing low-nicotine tobacco products |
WO2021113337A1 (en) * | 2019-12-03 | 2021-06-10 | Altria Client Services Llc | Compositions and methods for producing tobacco plants and products having altered alkaloid levels |
CN115927216A (zh) * | 2021-08-10 | 2023-04-07 | 深圳瑞德林生物技术有限公司 | 一种s-尼古丁的制备方法 |
-
2021
- 2021-04-19 WO PCT/JP2021/015920 patent/WO2021210688A1/ja unknown
- 2021-04-19 JP JP2022515456A patent/JP7210806B2/ja active Active
- 2021-04-19 EP EP21789517.6A patent/EP4136964A4/en active Pending
- 2021-04-19 BR BR112022021066A patent/BR112022021066A2/pt not_active Application Discontinuation
- 2021-04-19 CN CN202180028659.6A patent/CN115485386B/zh active Active
-
2022
- 2022-10-13 US US17/965,450 patent/US20230120622A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4136964A4 (en) | 2024-05-22 |
JPWO2021210688A1 (pt) | 2021-10-21 |
CN115485386A (zh) | 2022-12-16 |
WO2021210688A1 (ja) | 2021-10-21 |
CN115485386B (zh) | 2024-03-29 |
JP7210806B2 (ja) | 2023-01-23 |
EP4136964A1 (en) | 2023-02-22 |
US20230120622A1 (en) | 2023-04-20 |
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Legal Events
Date | Code | Title | Description |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |