JP2017518070A5 - - Google Patents

Download PDF

Info

Publication number
JP2017518070A5
JP2017518070A5 JP2017503766A JP2017503766A JP2017518070A5 JP 2017518070 A5 JP2017518070 A5 JP 2017518070A5 JP 2017503766 A JP2017503766 A JP 2017503766A JP 2017503766 A JP2017503766 A JP 2017503766A JP 2017518070 A5 JP2017518070 A5 JP 2017518070A5
Authority
JP
Japan
Prior art keywords
tumor
tissue
bioink
stromal
interstitial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2017503766A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017518070A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/041419 external-priority patent/WO2015152954A1/en
Publication of JP2017518070A publication Critical patent/JP2017518070A/ja
Publication of JP2017518070A5 publication Critical patent/JP2017518070A5/ja
Withdrawn legal-status Critical Current

Links

JP2017503766A 2014-04-04 2014-06-06 人工的な三次元の乳房組織、脂肪組織、および腫瘍疾患モデル Withdrawn JP2017518070A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461975640P 2014-04-04 2014-04-04
US61/975,640 2014-04-04
US201461976895P 2014-04-08 2014-04-08
US61/976,895 2014-04-08
PCT/US2014/041419 WO2015152954A1 (en) 2014-04-04 2014-06-06 Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model

Publications (2)

Publication Number Publication Date
JP2017518070A JP2017518070A (ja) 2017-07-06
JP2017518070A5 true JP2017518070A5 (enExample) 2017-08-17

Family

ID=54208710

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017503766A Withdrawn JP2017518070A (ja) 2014-04-04 2014-06-06 人工的な三次元の乳房組織、脂肪組織、および腫瘍疾患モデル

Country Status (10)

Country Link
US (5) US20170023550A1 (enExample)
EP (2) EP3126490B1 (enExample)
JP (1) JP2017518070A (enExample)
KR (1) KR20170013865A (enExample)
CN (1) CN106536720B (enExample)
AU (1) AU2014389440A1 (enExample)
CA (2) CA3177480A1 (enExample)
DK (1) DK3126490T3 (enExample)
IL (1) IL248164A0 (enExample)
WO (1) WO2015152954A1 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005081970A2 (en) 2004-02-24 2005-09-09 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
CA2729559C (en) 2008-06-24 2017-01-03 The Curators Of The University Of Missouri Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same
WO2011140441A2 (en) 2010-05-06 2011-11-10 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
WO2012054195A2 (en) 2010-10-21 2012-04-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
US20140099709A1 (en) * 2012-06-19 2014-04-10 Organovo, Inc. Engineered three-dimensional connective tissue constructs and methods of making the same
AU2014389440A1 (en) 2014-04-04 2016-10-20 Oregon Health & Science University Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model
EP3712254A1 (en) 2014-05-28 2020-09-23 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
EP3207123A1 (en) 2014-10-17 2017-08-23 Children's Hospital Center D/b/a Cincinnati Children's Hospital Medical Center In vivo model of human small intestine using pluripotent stem cells and methods of making and using same
US20160122723A1 (en) 2014-11-05 2016-05-05 Organovo, Inc. Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same
AU2016352873B2 (en) 2015-11-09 2023-01-05 Organovo, Inc. Improved methods for tissue fabrication
KR101803618B1 (ko) * 2015-12-10 2017-12-01 포항공과대학교 산학협력단 종양 조직 배양 장치 및 종양 조직 배양 방법
WO2017123722A1 (en) * 2016-01-12 2017-07-20 Cleveland State University 3d-printed miniature biological constructs
WO2017192997A1 (en) 2016-05-05 2017-11-09 Children's Hospital Medical Center Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
US10345208B2 (en) 2016-07-12 2019-07-09 Deka Products Limited Partnership System and method for applying force to a device
EP4478049A3 (en) * 2016-08-03 2024-12-25 Wake Forest University Health Sciences Cancer modeling platforms and methods of using the same
WO2018035138A1 (en) * 2016-08-15 2018-02-22 Organovo, Inc. Three dimensional bioprinted tumor models for drug testing
EP3534919A4 (en) 2016-11-04 2020-11-11 Children's Hospital Medical Center Liver organoid compositions and methods of making and using same
GB2555787A (en) 2016-11-07 2018-05-16 Landberg Goran Diagnostic methods
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
JP7300986B2 (ja) 2016-11-10 2023-06-30 オルガノボ インコーポレイテッド 人工腸組織およびその使用
CN110087772B (zh) 2016-11-17 2022-07-19 克利夫兰州立大学 用于微阵列3d生物打印的芯片平台
KR102807995B1 (ko) 2016-12-05 2025-05-16 칠드런즈 호스피탈 메디칼 센터 결장 유사장기 및 이를 제조 및 사용하는 방법
IL249977A0 (en) 2017-01-08 2017-04-30 Ramot At Tel-Aviv Univ Ltd 3D models of crops, methods for their preparation and their uses
US12281334B2 (en) 2017-04-14 2025-04-22 Children's Hospital Medical Center Multi donor stem cell compositions and methods of making same
WO2019002912A1 (en) * 2017-06-27 2019-01-03 ETH Zürich NANOCOMPOSITE MATERIALS COMPRISING CATIONIC NANOPARTICLES AND ANIONIC POLYMERS USEFUL IN METHODS FOR THEIR 3D PRINTING
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
US12297416B2 (en) 2017-07-12 2025-05-13 Deka Products Limited Partneship System and method for transferring tissue
CN110998320B (zh) * 2017-08-21 2024-04-09 凸版印刷株式会社 抗癌效果的评价方法及癌症免疫疗法的有效性预测方法
CN111051495A (zh) * 2017-08-21 2020-04-21 凸版印刷株式会社 原代培养方法
CA3077442A1 (en) 2017-10-10 2019-04-18 Children's Hospital Medical Center Esophageal tissue and/or organoid compositions and methods of making same
US11262349B2 (en) 2017-10-11 2022-03-01 Cleveland State University Multiplexed immune cell assays on a micropillar/microwell chip platform
WO2019126626A1 (en) 2017-12-21 2019-06-27 Children's Hospital Medical Center Digitalized human organoids and methods of using same
AU2019215096B2 (en) 2018-02-02 2025-04-10 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same
CN108396007B (zh) * 2018-03-15 2021-07-23 东北农业大学 体外构建奶牛血乳屏障三维模型的方法
SG11202100533VA (en) 2018-07-26 2021-02-25 Childrens Hospital Med Ct Hepato-biliary-pancreatic tissues and methods of making same
TWI732132B (zh) * 2018-09-05 2021-07-01 國立臺灣大學 製造模擬血管新生的細胞球的方法及其應用
WO2020056158A1 (en) 2018-09-12 2020-03-19 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
EP3873504B1 (en) * 2018-11-01 2023-12-13 North Carolina State University Adipocyte mediated delivery of anticancer therapeutics
CA3141807A1 (en) 2019-05-31 2020-12-03 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
US12019040B2 (en) 2019-09-30 2024-06-25 Cornell University System and devices for monitoring cell-containing materials and methods of their use
KR102214911B1 (ko) * 2019-11-18 2021-02-10 한국생산기술연구원 3d 프린터로 제작된 몰드를 이용한 유방 및 종양 모형 제조방법
KR102263745B1 (ko) * 2019-12-05 2021-06-09 포항공과대학교 산학협력단 흑색종 모델 및 이의 제조방법
DE102020004900A1 (de) 2020-08-12 2022-02-17 Universitätsmedizin Der Johannes Gutenberg-Universität Mainz Autologe prävaskulisierte 3D-Druckverfahren-erzeugte Brustgewebe-Konstrukte und Verfahren zu deren Herstellung
EP4255413A4 (en) * 2020-12-07 2024-10-02 The Regents of University of California TISSUE ORGANOID BIOPRINTING AND HIGH-THROUGHPUT SCREENING
EP4259659A4 (en) * 2020-12-08 2025-02-12 Cornell University METHODS FOR INDUCING AN IMMUNOMODULATORY TUMOR RESPONSE
WO2022225845A1 (en) * 2021-04-18 2022-10-27 Mary Hitchcock Memorial Hospital, For Itself And On Behalf Of Dartmouth-Hitchcock Clinic System and method for automation of surgical pathology processes using artificial intelligence
CN113444691A (zh) * 2021-06-21 2021-09-28 河南省人民医院 一种模拟乳腺癌放疗后血管再生的体外细胞模型及其制备方法和应用
TW202306575A (zh) * 2021-06-23 2023-02-16 日商Ａｄｅｋａ股份有限公司 去細胞化細胞結構體
WO2024188290A1 (en) * 2023-03-14 2024-09-19 The University Of Hong Kong 3d bioprinting of tumor tissue for mechanistic study and drug screening
WO2024203556A1 (ja) * 2023-03-30 2024-10-03 Ｔｏｐｐａｎホールディングス株式会社 三次元乳腺モデル及びその製造方法

Family Cites Families (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4759764A (en) 1985-05-24 1988-07-26 Clayton Foundation For Research Peripheral nerve regeneration
US4808435A (en) 1987-04-06 1989-02-28 International Business Machines Corporation Screen printing method for producing lines of uniform width and height
US5099090A (en) 1988-05-11 1992-03-24 Ariel Electronics, Inc. Circuit writer
EP2075015B1 (en) 1997-07-03 2015-03-11 Massachusetts Institute of Technology Tissue-engineered constructs
US6401795B1 (en) 1997-10-28 2002-06-11 Sandia Corporation Method for freeforming objects with low-binder slurry
CA2326322C (en) 1998-04-21 2011-03-01 University Of Connecticut Free-form nanofabrication using multi-photon excitation
US6697694B2 (en) 1998-08-26 2004-02-24 Electronic Materials, L.L.C. Apparatus and method for creating flexible circuits
US7338798B2 (en) 1998-09-15 2008-03-04 The Regents Of The University Of Michigan System and method for forming a cardiac muscle construct
EP1029692B9 (en) 1999-02-17 2003-12-03 Hewlett-Packard Company, A Delaware Corporation Printing apparatus
US6979670B1 (en) 1999-03-10 2005-12-27 Biora Bioex Ab Matrix protein compositions for grafting
US6642243B1 (en) 1999-07-22 2003-11-04 Ashkan Imanzahrai Migraine medicine and method for treating same
JP2001145956A (ja) 1999-11-19 2001-05-29 Meiko:Kk 光硬化性樹脂三次元造形物の積層造形装置及びその積層造形方法
US6503273B1 (en) 1999-11-22 2003-01-07 Cyograft Tissue Engineering, Inc. Tissue engineered blood vessels and methods and apparatus for their manufacture
US6454972B1 (en) 1999-11-24 2002-09-24 Sandia Corporation Solid freeform fabrication using chemically reactive suspensions
US6520997B1 (en) 1999-12-08 2003-02-18 Baxter International Inc. Porous three dimensional structure
US6315469B1 (en) 2000-01-19 2001-11-13 Hewlett-Packard Company Tool and method for adjustment of printhead to platen spacing in a printer
DE10013223C2 (de) 2000-03-13 2002-07-18 Co Don Ag Verfahren zur in vitro-Herstellung von dreidimensionalem, vitalem Knorpel- oder Knochengewebe und dessen Verwendung als Transplantationsmaterial
US20050091576A1 (en) 2003-10-24 2005-04-28 Microsoft Corporation Programming interface for a computer platform
DE10018987A1 (de) 2000-04-17 2001-10-31 Envision Technologies Gmbh Vorrichtung und Verfahren zum Herstellen von dreidimensionalen Objekten
US20020182633A1 (en) 2000-07-11 2002-12-05 Chen Christopher S. Methods of patterning protein and cell adhesivity
US7998735B2 (en) 2000-08-21 2011-08-16 Victorian Tissue Engineering Centre Pty. Ltd. Vascularized tissue graft
US6561607B1 (en) 2000-10-05 2003-05-13 Eastman Kodak Company Apparatus and method for maintaining a substantially constant closely spaced working distance between an inkjet printhead and a printing receiver
US6939489B2 (en) 2001-03-23 2005-09-06 Ivoclar Vivadent Ag Desktop process for producing dental products by means of 3-dimensional plotting
WO2002085246A2 (en) 2001-04-19 2002-10-31 Case Western Reserve University Fabrication of a polymeric prosthetic implant
DE10127225A1 (de) 2001-05-22 2002-11-28 Zeiss Carl Ultraviolettlicht-Abschwächungsfilter
US20030049839A1 (en) 2001-08-01 2003-03-13 The University Of Texas System Transparent multi-channel cell scaffold that creates a cellular and/or molecular gradient
WO2003017745A2 (en) 2001-08-23 2003-03-06 Sciperio, Inc. Architecture tool and methods of use
US6934600B2 (en) 2002-03-14 2005-08-23 Auburn University Nanotube fiber reinforced composite materials and method of producing fiber reinforced composites
US20030175410A1 (en) 2002-03-18 2003-09-18 Campbell Phil G. Method and apparatus for preparing biomimetic scaffold
US20100254900A1 (en) 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US6907307B2 (en) 2002-07-02 2005-06-14 3D Systems, Inc. Support volume calculation for a CAD model
AU2003251874A1 (en) 2002-07-12 2004-02-02 Dirk R. Albrecht Three dimensional cell patterned bioploymer scaffolds and method of making the same
US6998264B2 (en) 2002-11-19 2006-02-14 Huntington Medical Research Institutes Replication of biological tissue
US7641898B2 (en) 2003-03-21 2010-01-05 Materials Evolution And Development Usa, Inc. Keratinocyte-fibrocyte concomitant grafting for wound healing
US20040197375A1 (en) 2003-04-02 2004-10-07 Alireza Rezania Composite scaffolds seeded with mammalian cells
US7051654B2 (en) 2003-05-30 2006-05-30 Clemson University Ink-jet printing of viable cells
US7338517B2 (en) 2003-06-04 2008-03-04 University Of South Carolina Tissue scaffold having aligned fibrils and artificial tissue comprising the same
JP4474858B2 (ja) 2003-07-07 2010-06-09 セイコーエプソン株式会社 ギャップ調整装置、これに使用されるキャリブレーション用治具、およびギャップ調整装置を備えた液滴吐出装置、並びに電気光学装置の製造方法
US20050074877A1 (en) 2003-07-28 2005-04-07 Mao Jeremy Jian Biological engineering of articular structures containing both cartilage and bone
US8043614B2 (en) 2004-03-09 2011-10-25 Ahlfors Jan-Eric W Autogenic living scaffolds and living tissue matrices: methods and uses thereof
FR2859128B1 (fr) 2003-08-29 2006-03-10 Centre Nat Rech Scient Procede et dispositif de fabrication d'un composant multimateriaux tridimensionnel par impression du type jet d'encre
DE10353281A1 (de) 2003-11-14 2005-06-16 Bayer Cropscience Ag Wirkstoffkombination mit insektiziden und akariziden Eigenschaften
US20050276791A1 (en) 2004-02-20 2005-12-15 The Ohio State University Multi-layer polymer scaffolds
WO2005081970A2 (en) 2004-02-24 2005-09-09 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
US20090142307A1 (en) 2004-07-09 2009-06-04 Athanasiou Kyriacos A Shape-Based Approach for Scaffoldless Tissue Engineering
US7939003B2 (en) 2004-08-11 2011-05-10 Cornell Research Foundation, Inc. Modular fabrication systems and methods
US7651665B2 (en) 2004-09-07 2010-01-26 Hewlett-Packard Development Company, L.P. Microtray for handling biosubstances
US7767446B2 (en) 2004-09-16 2010-08-03 Becton, Dickinson And Company Perfusion bioreactors for culturing cells
KR100606457B1 (ko) 2004-11-11 2006-11-23 한국기계연구원 3차원 프린팅 조형시스템
JP4539316B2 (ja) 2004-12-08 2010-09-08 セイコーエプソン株式会社 ヘッド位置補正方法およびヘッド位置補正装置、並びに液滴吐出装置、電気光学装置の製造方法
US7568904B2 (en) 2005-03-03 2009-08-04 Laser Solutions Co., Ltd. Stereolithography apparatus
JP4729948B2 (ja) 2005-03-09 2011-07-20 ブラザー工業株式会社 液体供給装置、この液体供給装置を備えたインクジェット記録装置
US7780897B2 (en) 2005-04-22 2010-08-24 Board Of Regents, The University Of Texas System Hydrogel constructs using stereolithography
AU2006250079B2 (en) 2005-05-24 2012-05-31 The Regents Of The University Of California Microscale micropatterned engineered in vitor tissue
EP1934288A2 (en) 2005-07-28 2008-06-25 Carnegie Mellon University Biocompatible polymers and methods of use
US8690957B2 (en) 2005-12-21 2014-04-08 Warsaw Orthopedic, Inc. Bone graft composition, method and implant
US20070200276A1 (en) 2006-02-24 2007-08-30 Micron Technology, Inc. Method for rapid printing of near-field and imprint lithographic features
US7680555B2 (en) 2006-04-03 2010-03-16 Stratasys, Inc. Auto tip calibration in an extrusion apparatus
US20070231787A1 (en) 2006-04-04 2007-10-04 Voelker Mark A Methods and devices for imaging and manipulating biological samples
AU2007234366A1 (en) 2006-04-05 2007-10-11 William Marsh Rice University Chondrocyte differentiation from human embryonic stem cells and their use in tissue engineering
US20090208466A1 (en) 2006-04-21 2009-08-20 James Yoo Ink-jet printing of tissues
WO2007124481A2 (en) 2006-04-21 2007-11-01 Drexel University Bioprinting three-dimensional structures onto microscale tissue analog devices for pharmacokinetic study and other uses
JP4051077B2 (ja) 2006-04-28 2008-02-20 シャープ株式会社 液滴塗布装置、液滴吐出部のギャップ測定方法、および、液滴吐出部のギャップ調整方法
FR2901143B1 (fr) 2006-05-16 2008-10-03 Centre Nat Rech Scient "methode de construction de materiaux vivants fonctionnels, materiaux obtenus et applications"
US7959942B2 (en) 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
DE102006053121B3 (de) 2006-11-10 2007-12-27 Eos Gmbh Electro Optical Systems Vorrichtung und Verfahren zum Herstellen eines dreidimensionalen Objektes mittels eines Beschichters für pulverförmiges Aufbaumaterial
US8097455B2 (en) 2007-02-02 2012-01-17 The Regents Of The University Of Michigan System and method for forming skeletal muscle constructs having functional tissue interfaces
US8343740B2 (en) 2007-03-29 2013-01-01 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Micro-organ device
CA2688055C (en) 2007-06-07 2018-02-06 Wake Forest University Health Sciences Inkjet gene printing
WO2009013751A2 (en) 2007-07-25 2009-01-29 Objet Geometries Ltd. Solid freeform fabrication using a plurality of modeling materials
AU2008292089B2 (en) 2007-08-29 2011-09-29 Vito Nv Method for producing a three-dimensional macroporous filament construct based on phase inversion and construct thereby obtained
US20090076531A1 (en) 2007-09-18 2009-03-19 Richardson Charles L Method and apparatus for bypass graft
WO2009051701A2 (en) 2007-10-15 2009-04-23 Wake Forest University Health Sciences Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
KR100922232B1 (ko) 2008-02-13 2009-10-16 연세대학교 산학협력단 전기수력학 프린팅 기법을 이용한 살아있는 세포의 직접패터닝 방법 및 장치
EP2090584A1 (en) 2008-02-13 2009-08-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Identification of a novel cysteine-rich cell penetrating peptide
US8691274B2 (en) 2008-02-14 2014-04-08 Wake Forest University Health Sciences Inkjet printing of tissues and cells
US20090248145A1 (en) 2008-03-28 2009-10-01 Nanyang Technological University Method of forming a three-dimensional structure of unidirectionally aligned cells
US8876513B2 (en) 2008-04-25 2014-11-04 3D Systems, Inc. Selective deposition modeling using CW UV LED curing
SI2310491T1 (en) 2008-06-20 2018-07-31 Universiteit Maastricht Only composite tissue modules
CA2729559C (en) 2008-06-24 2017-01-03 The Curators Of The University Of Missouri Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same
US9097702B2 (en) * 2008-07-29 2015-08-04 Cornell University Pathologically relevant tumor microenvironments for high-throughput drug screening
WO2010030964A2 (en) 2008-09-12 2010-03-18 The Brigham And Women's Hospital, Inc. 3-dimensional multi-layered hydrogels and methods of making the same
WO2010060080A1 (en) 2008-11-24 2010-05-27 Immunotrex Corporation Three dimensional tissue generation
EP2384439A4 (en) * 2009-01-30 2013-06-05 Univ Utah Res Found CROSS-LINKED HYDROGELE WITH GOLD NANOPARTICLES
EP2450707B1 (en) * 2010-11-04 2016-04-27 University of Pécs Lung tissue model
WO2011038373A2 (en) 2009-09-28 2011-03-31 Virginia Tech Intellectual Properties, Inc. Three-dimensional bioprinting of biosynthetic cellulose (bc) implants and scaffolds for tissue engineering
US8409603B2 (en) 2009-10-01 2013-04-02 University Of South Carolina Compositions and methods for tissue engineering, tissue regeneration and wound healing
US20110177590A1 (en) 2009-12-11 2011-07-21 Drexel University Bioprinted Nanoparticles and Methods of Use
US10500384B2 (en) 2010-01-08 2019-12-10 Wake Forest University Health Sciences Delivery system
WO2011088213A1 (en) 2010-01-15 2011-07-21 University Of Utah Research Foundation Crosslinked hydrogels and methods of making and using thereof
KR20120125331A (ko) 2010-02-02 2012-11-14 더 큐레이터스 오브 더 유니버시티 오브 미주리 조작된 생물학적 신경 이식편 제조 및 그의 적용
ES2671594T3 (es) 2010-03-04 2018-06-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Puesto de bioimpresión, ensamblaje que comprende dicho puesto de bioimpresión y método de bioimpresión
GB2478801B (en) 2010-03-16 2012-05-30 Organovo Inc Multilayered vascular tubes
US9012415B2 (en) 2010-03-26 2015-04-21 Stemmatters, Biotecnologia E Medicina Regenerativa S.A. Photo-crosslinked gellan gum-based hydrogels: preparation methods and uses thereof
US9592255B2 (en) 2010-07-01 2017-03-14 The Regents Of The University Of Michigan Scaffold-free three dimensional nerve fibroblast constructs
US20120089238A1 (en) 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
WO2012054195A2 (en) * 2010-10-21 2012-04-26 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue
DE202011003443U1 (de) 2011-03-02 2011-12-23 Bego Medical Gmbh Vorrichtung zur generativen Herstellung dreidimensionaler Bauteile
CA2828705A1 (en) 2011-03-07 2012-09-13 Wake Forest University Health Sciences Delivery system
GB201105226D0 (en) * 2011-03-29 2011-05-11 Univ Leiden Methods
JP5599356B2 (ja) 2011-03-31 2014-10-01 富士フイルム株式会社 シミュレーション方法、プログラムおよびそれを記録した記録媒体、並びに、それらを利用した液滴配置パターンの作成方法、ナノインプリント方法、パターン化基板の製造方法およびインクジェット装置。
WO2013040087A2 (en) 2011-09-12 2013-03-21 Organovo, Inc. Platform for engineered implantable tissues and organs and methods of making the same
CA2848043C (en) * 2011-09-12 2022-07-12 Organovo, Inc. Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same
US10059056B2 (en) 2012-02-01 2018-08-28 Nscrypt, Inc. Micro-dispensing multi-layered 3D objects with curing steps
WO2013130823A1 (en) 2012-02-29 2013-09-06 Massachusetts Institute Of Technology Inverse patterning process for three-dimensional multi-compartmental micro-organization of multiple cell types
CA2866267A1 (en) * 2012-03-06 2013-09-12 The Uab Research Foundation Three-dimesional, prevascularized, engineered tissue constructs, methods of making and methods of using the tissue constructs
US9499779B2 (en) * 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
US20140099709A1 (en) * 2012-06-19 2014-04-10 Organovo, Inc. Engineered three-dimensional connective tissue constructs and methods of making the same
US9399322B2 (en) 2012-08-08 2016-07-26 Makerbot Industries, Llc Three dimensional printer with removable, replaceable print nozzle
US9442105B2 (en) 2013-03-15 2016-09-13 Organovo, Inc. Engineered liver tissues, arrays thereof, and methods of making the same
US20140265046A1 (en) 2013-03-15 2014-09-18 Matterfab Corp. Laser sintering apparatus and methods
US9802360B2 (en) 2013-06-04 2017-10-31 Stratsys, Inc. Platen planarizing process for additive manufacturing system
CA2919734C (en) 2013-07-31 2023-04-25 Organovo, Inc. Automated devices, systems, and methods for the fabrication of tissue
AU2014389440A1 (en) 2014-04-04 2016-10-20 Oregon Health & Science University Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model

Similar Documents

Publication Publication Date Title
JP2017518070A5 (enExample)
Lovett et al. Innovations in 3D tissue models of human brain physiology and diseases
Wang et al. Constructing tissuelike complex structures using cell-laden DNA hydrogel bricks
Ventre et al. Engineering cell instructive materials to control cell fate and functions through material cues and surface patterning
JP2015523142A5 (enExample)
Pampaloni et al. Three-dimensional tissue models for drug discovery and toxicology
JP2017529877A5 (enExample)
JP7026040B2 (ja) 連続的にバイオプリントされた多層組織構造体
RU2017110275A (ru) Сконструированные ткани почки, матрицы на их основе и способы их получения
JP2019530435A (ja) 薬物試験のための三次元バイオプリント腫瘍モデル
Xu et al. 3D bioprinting of multi-cellular tumor microenvironment for prostate cancer metastasis
WO2006075597A1 (ja) 伸展方向が制御された細胞の培養方法
KR101837293B1 (ko) 인간 타액선 세포 기반 3차원 체외 배양을 통한 선 조직 유사 오가노이드 형성 방법 및 이를 이용한 타액선 질환 모델의 용도
Wang et al. Nanostructured architectures promote the mesenchymal–epithelial transition for invasive cells
CN103898055B (zh) 不同基底硬度体外细胞培养平台的建立方法
JP6468714B2 (ja) 培養容器及びそれを利用した複数の積層細胞シートの作製方法
CN108699520A (zh) 细胞块、细胞结构体以及立体组织体
Huang et al. Generation of interconnected neural clusters in multiscale scaffolds from human-induced pluripotent stem cells
JP6837333B2 (ja) シート状細胞培養物を製造するための細胞培養器具およびそれを用いたシート状細胞培養物の製造方法
Hou et al. Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment
WO2024188290A1 (en) 3d bioprinting of tumor tissue for mechanistic study and drug screening
Liu et al. Functional Blood–Brain Barrier Model with Tight Connected Minitissue by Liquid Substrates Culture
US20150353894A1 (en) Engineered physical alignment of stem cell-derived cardiomyocytes
JP6674946B2 (ja) シート状細胞培養物の評価方法
JP6029102B2 (ja) 三次元培養弾性線維組織の製造方法