CN106536720B - 工程化的三维乳腺组织,脂肪组织和肿瘤疾病模型 - Google Patents
工程化的三维乳腺组织,脂肪组织和肿瘤疾病模型 Download PDFInfo
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- CN106536720B CN106536720B CN201480079583.XA CN201480079583A CN106536720B CN 106536720 B CN106536720 B CN 106536720B CN 201480079583 A CN201480079583 A CN 201480079583A CN 106536720 B CN106536720 B CN 106536720B
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- B33—ADDITIVE MANUFACTURING TECHNOLOGY
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- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- G01N33/5082—Supracellular entities, e.g. tissue, organisms
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1305—Adipocytes
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1352—Mesenchymal stem cells
- C12N2502/1358—Bone marrow mesenchymal stem cells (BM-MSC)
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461975640P | 2014-04-04 | 2014-04-04 | |
| US61/975,640 | 2014-04-04 | ||
| US201461976895P | 2014-04-08 | 2014-04-08 | |
| US61/976,895 | 2014-04-08 | ||
| PCT/US2014/041419 WO2015152954A1 (en) | 2014-04-04 | 2014-06-06 | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106536720A CN106536720A (zh) | 2017-03-22 |
| CN106536720B true CN106536720B (zh) | 2021-04-30 |
Family
ID=54208710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480079583.XA Expired - Fee Related CN106536720B (zh) | 2014-04-04 | 2014-06-06 | 工程化的三维乳腺组织,脂肪组织和肿瘤疾病模型 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US20170023550A1 (enExample) |
| EP (2) | EP3808838B1 (enExample) |
| JP (1) | JP2017518070A (enExample) |
| KR (1) | KR20170013865A (enExample) |
| CN (1) | CN106536720B (enExample) |
| AU (1) | AU2014389440A1 (enExample) |
| CA (2) | CA3177480A1 (enExample) |
| DK (1) | DK3126490T3 (enExample) |
| IL (1) | IL248164A0 (enExample) |
| WO (1) | WO2015152954A1 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005081970A2 (en) | 2004-02-24 | 2005-09-09 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
| JP5624981B2 (ja) | 2008-06-24 | 2014-11-12 | ザ・キュレーターズ・オブ・ザ・ユニバーシティ・オブ・ミズーリThe Curators Ofthe University Of Missouri | 自己集合性多細胞体、および前記多細胞体を用いて3次元の生物構造体を作製する方法 |
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| KR20160125530A (ko) | 2010-10-21 | 2016-10-31 | 오가노보, 인크. | 조직의 제작을 위한 디바이스, 시스템 및 방법 |
| US20140099709A1 (en) * | 2012-06-19 | 2014-04-10 | Organovo, Inc. | Engineered three-dimensional connective tissue constructs and methods of making the same |
| EP3808838B1 (en) | 2014-04-04 | 2024-04-10 | Organovo, Inc. | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
| EP3149156B1 (en) | 2014-05-28 | 2021-02-17 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のin vivoモデル、並びにそれを作製、及び使用する方法 |
| US11529436B2 (en) | 2014-11-05 | 2022-12-20 | Organovo, Inc. | Engineered three-dimensional skin tissues, arrays thereof, and methods of making the same |
| AU2016352873B2 (en) | 2015-11-09 | 2023-01-05 | Organovo, Inc. | Improved methods for tissue fabrication |
| KR101803618B1 (ko) * | 2015-12-10 | 2017-12-01 | 포항공과대학교 산학협력단 | 종양 조직 배양 장치 및 종양 조직 배양 방법 |
| US10934538B2 (en) * | 2016-01-12 | 2021-03-02 | Cleveland State University | 3D-printed miniature biological constructs |
| EP4177335A1 (en) | 2016-05-05 | 2023-05-10 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| US11254901B2 (en) | 2016-07-12 | 2022-02-22 | Deka Products Limited Partnership | System and method for printing tissue |
| US10345208B2 (en) | 2016-07-12 | 2019-07-09 | Deka Products Limited Partnership | System and method for applying force to a device |
| AU2017306548B2 (en) * | 2016-08-03 | 2024-02-01 | Wake Forest University Health Sciences | Cancer modeling platforms and methods of using the same |
| JP2019530435A (ja) * | 2016-08-15 | 2019-10-24 | オルガノボ インコーポレイテッド | 薬物試験のための三次元バイオプリント腫瘍モデル |
| EP3534976A4 (en) | 2016-11-04 | 2020-09-16 | Children's Hospital Medical Center | PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE |
| GB2555787A (en) | 2016-11-07 | 2018-05-16 | Landberg Goran | Diagnostic methods |
| US11299705B2 (en) | 2016-11-07 | 2022-04-12 | Deka Products Limited Partnership | System and method for creating tissue |
| US11655456B2 (en) | 2016-11-10 | 2023-05-23 | Organovo, Inc. | Engineered intestinal tissue and uses thereof |
| EP3541518A4 (en) | 2016-11-17 | 2020-09-30 | Cleveland State University | CHIP PLATFORMS FOR MICRO-NETWORK 3D BIO-PRINTING |
| EP3548507A4 (en) | 2016-12-05 | 2020-07-15 | Children's Hospital Medical Center | COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| IL249977A0 (en) | 2017-01-08 | 2017-04-30 | Ramot At Tel-Aviv Univ Ltd | 3D models of crops, methods for their preparation and their uses |
| EP3609997A4 (en) | 2017-04-14 | 2021-03-03 | Children's Hospital Medical Center | COMPOSITIONS OF STEM CELLS FROM MULTIPLE DONOR CELLS AND THEIR PREPARATION PROCEDURES |
| WO2019002912A1 (en) * | 2017-06-27 | 2019-01-03 | ETH Zürich | NANOCOMPOSITE MATERIALS COMPRISING CATIONIC NANOPARTICLES AND ANIONIC POLYMERS USEFUL IN METHODS FOR THEIR 3D PRINTING |
| US10570362B2 (en) | 2017-07-12 | 2020-02-25 | Deka Products Limited Partnership | System and method for transferring tissue |
| US12297416B2 (en) | 2017-07-12 | 2025-05-13 | Deka Products Limited Partneship | System and method for transferring tissue |
| JP6915692B2 (ja) * | 2017-08-21 | 2021-08-04 | 凸版印刷株式会社 | 抗がん効果の評価方法、及びがん免疫療法の奏効性予測方法 |
| CN111051495A (zh) * | 2017-08-21 | 2020-04-21 | 凸版印刷株式会社 | 原代培养方法 |
| EP3694603A4 (en) | 2017-10-10 | 2021-07-14 | Children's Hospital Medical Center | ESOPHAGUS TISSUE AND / OR ORGANOID COMPOSITIONS AND METHOD FOR MANUFACTURING THEREOF |
| US11262349B2 (en) | 2017-10-11 | 2022-03-01 | Cleveland State University | Multiplexed immune cell assays on a micropillar/microwell chip platform |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| KR102820005B1 (ko) | 2018-02-02 | 2025-06-12 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | 면역요법 관련 오가노이드 및 그의 제조 및 사용 방법 |
| CN108396007B (zh) * | 2018-03-15 | 2021-07-23 | 东北农业大学 | 体外构建奶牛血乳屏障三维模型的方法 |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| TWI732132B (zh) * | 2018-09-05 | 2021-07-01 | 國立臺灣大學 | 製造模擬血管新生的細胞球的方法及其應用 |
| WO2020056158A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| US20210369787A1 (en) * | 2018-11-01 | 2021-12-02 | North Carolina State University | Adipocyte mediated delivery of anticancer therapeutics |
| US12019040B2 (en) | 2019-09-30 | 2024-06-25 | Cornell University | System and devices for monitoring cell-containing materials and methods of their use |
| KR102214911B1 (ko) * | 2019-11-18 | 2021-02-10 | 한국생산기술연구원 | 3d 프린터로 제작된 몰드를 이용한 유방 및 종양 모형 제조방법 |
| KR102263745B1 (ko) * | 2019-12-05 | 2021-06-09 | 포항공과대학교 산학협력단 | 흑색종 모델 및 이의 제조방법 |
| DE102020004900A1 (de) | 2020-08-12 | 2022-02-17 | Universitätsmedizin Der Johannes Gutenberg-Universität Mainz | Autologe prävaskulisierte 3D-Druckverfahren-erzeugte Brustgewebe-Konstrukte und Verfahren zu deren Herstellung |
| WO2022125585A1 (en) * | 2020-12-07 | 2022-06-16 | The Regents Of The University Of California | Tissue organoid bioprinting and high-throughput screening methodology |
| WO2022125652A1 (en) * | 2020-12-08 | 2022-06-16 | Cornell University | Methods of inducing an immunomodulatory tumor response |
| WO2022225845A1 (en) * | 2021-04-18 | 2022-10-27 | Mary Hitchcock Memorial Hospital, For Itself And On Behalf Of Dartmouth-Hitchcock Clinic | System and method for automation of surgical pathology processes using artificial intelligence |
| CN113444691A (zh) * | 2021-06-21 | 2021-09-28 | 河南省人民医院 | 一种模拟乳腺癌放疗后血管再生的体外细胞模型及其制备方法和应用 |
| TW202306575A (zh) * | 2021-06-23 | 2023-02-16 | 日商Adeka股份有限公司 | 去細胞化細胞結構體 |
| CN120936704A (zh) * | 2023-03-14 | 2025-11-11 | 香港大学 | 用于机制研究和药物筛选的肿瘤组织的3d生物打印 |
| CN120641555A (zh) * | 2023-03-30 | 2025-09-12 | 凸版控股株式会社 | 三维乳腺模型及其制造方法 |
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| WO2013192290A1 (en) * | 2012-06-19 | 2013-12-27 | Organovo, Inc. | Engineered three-dimensional connective tissue constructs and methods of making the same |
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| CA2944723C (en) | 2023-03-14 |
| US20180196034A1 (en) | 2018-07-12 |
| EP3808838A1 (en) | 2021-04-21 |
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| US20170023550A1 (en) | 2017-01-26 |
| EP3126490A1 (en) | 2017-02-08 |
| CN106536720A (zh) | 2017-03-22 |
| EP3808838B1 (en) | 2024-04-10 |
| EP3126490A4 (en) | 2017-09-13 |
| US9983195B2 (en) | 2018-05-29 |
| JP2017518070A (ja) | 2017-07-06 |
| US20200116702A1 (en) | 2020-04-16 |
| WO2015152954A1 (en) | 2015-10-08 |
| US11789011B2 (en) | 2023-10-17 |
| DK3126490T3 (da) | 2021-01-04 |
| US20150282885A1 (en) | 2015-10-08 |
| US20240168010A1 (en) | 2024-05-23 |
| KR20170013865A (ko) | 2017-02-07 |
| IL248164A0 (en) | 2016-11-30 |
| AU2014389440A1 (en) | 2016-10-20 |
| CA3177480A1 (en) | 2015-10-08 |
| CA2944723A1 (en) | 2015-10-08 |
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